Basic Information

Insect: Drosophila virilis
Gene Symbol: su(Hw)
Assembly: GCA_007989325.2
Location: CM017605.2:933375-941786[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00062 0.037 14.2 2.2 1 20 291 310 291 312 0.94

2 12 2.6e-06 0.00015 21.7 0.4 3 23 363 384 361 384 0.93

3 12 0.094 5.6 7.3 0.1 1 23 390 412 390 412 0.96

4 12 7e-07 4.2e-05 23.4 2.5 1 21 419 439 419 440 0.95

5 12 3e-06 0.00018 21.4 0.6 2 23 452 473 451 473 0.96

6 12 9.8e-05 0.0058 16.7 5.3 1 23 484 506 484 506 0.99

7 12 7.6e-05 0.0045 17.0 0.9 1 23 512 534 512 534 0.97

8 12 1.5e-05 0.0009 19.2 0.8 1 23 540 562 540 562 0.99

9 12 1.4e-06 8.3e-05 22.5 3.0 1 23 568 590 568 590 0.98

10 12 0.0059 0.35 11.1 0.8 1 23 594 616 594 616 0.96

11 12 9.6e-05 0.0057 16.7 0.2 1 20 624 643 624 648 0.92

12 12 3.4e-05 0.002 18.2 0.3 3 23 668 689 666 689 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00062	0.037	14.2	2.2	1	20	291	310	291	312	0.94
2	12	2.6e-06	0.00015	21.7	0.4	3	23	363	384	361	384	0.93
3	12	0.094	5.6	7.3	0.1	1	23	390	412	390	412	0.96
4	12	7e-07	4.2e-05	23.4	2.5	1	21	419	439	419	440	0.95
5	12	3e-06	0.00018	21.4	0.6	2	23	452	473	451	473	0.96
6	12	9.8e-05	0.0058	16.7	5.3	1	23	484	506	484	506	0.99
7	12	7.6e-05	0.0045	17.0	0.9	1	23	512	534	512	534	0.97
8	12	1.5e-05	0.0009	19.2	0.8	1	23	540	562	540	562	0.99
9	12	1.4e-06	8.3e-05	22.5	3.0	1	23	568	590	568	590	0.98
10	12	0.0059	0.35	11.1	0.8	1	23	594	616	594	616	0.96
11	12	9.6e-05	0.0057	16.7	0.2	1	20	624	643	624	648	0.92
12	12	3.4e-05	0.002	18.2	0.3	3	23	668	689	666	689	0.96

Sequence Information

Coding Sequence: atgattCAAATCGTTCAGTTAaagaatttattgaattttaagtCTCGAACGAGTAACGAGATTAGGAATGCGAGCGACAAAACAACGCCTGGTCACACCAATGTCAGCACAGCTGATTGTTTGTCTACGAAAAGTGTGAATAGTCCGACGCTAACGCCATTGTGTACGCTTACGTGCCTTTGCTCGAGCTGTGAATTTATTCTCGCAAGGCATTCAATGAGCGCCAGCAAGGACGCCCTACCGGCAACTCCCCCCGCCTCCAGCAGCATCAAAATTTCTGACGGCGACAAACCCAAGGAAAAACGCACTGGCACACGCATGAAGCTGCTCAACGATGTAGCAGCAAAGGCTGCAGTTGCCAGTAAAGGCGCCTCCGTATCGCCGCGCCTCAAGCCGGAGAAACGCACAAGCATTAAAatactcaacaacaacaacaacgatgaaGCTCAGACAAGTACAAAGGGCGGTGACAGGCGTGCCACGCCCAAAGCCGCCAGCACCAGCGTCAAGATATTGAACGAGAAGCGCTCGGCGCCGGCCAGCTCAGCTGTGGAAACAGCCAAGATAAAGACATCGCCcagcaagaagaaaaaaatggaTCACTATGTGCTGCAGGCCATCAAAAGTGAGAACAACAAGGCGGAGAACACGACCAGCGTCGTGGTCGTCGAGGACGAGGACACCATAGACTTTATACTGGCCGATGATGAAGTCGAGCTGGGTGCTGGAGCAAAGGAGAATGGTGAAGAATTTGTGGTATCTGGCGTggatgaggatgatgatgacgatgacgatgacgaggaTGAAGGTGTGGTGGAAGGTGGTGCCAAGCGCAGAAGCGGCAATAATGAACTCAAGGAAATGGTCGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGGCGCGTCAAAAGCCTAAAGAAACACCTGGAGTTCTGTCGCTACGACAGCGGCTATCATTTGCGCAAGGCGGACATGCTCAAGAATCTGGAGAAGATCGAGAAGGACGCCGTGGTCATGGAGAAGAAGGACAtctgcttctgctgcagcGAGAGCTACGACACCTTTCATCTGGGTCACATCAACTGCCCCGATTGCCCGAAGTCGTTCAAGACGCAGACTAGCTATGAGCGTCATATTTTCATAACACACTCGGAGTTCAATGATTATCCGTGCTCCATTTGCAATGCCAAGCTGAGGAGCGGCGCGCTGCTTAAGCTGcacgagcagcagcatcaattgCGCGGCAAGCCGTTTGCCTGCAAAATCTGTGGCAAGGACTTTACGCGCTCGTATCACCTGAAGCGCCATCAGAAATACTCGTCCTGCTCGGCCAATGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCCTCGACAATTTGCGCGCTCATCTCAAACAGCATCTGGGCACCCAGGTGGTCAAGAAACCCGAGTACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTCTCTCCACACTCAACATTCACATACGCACCCATACGGGCGAGAAGCCCTTTGATTGTGATCTATGCGACAAAAAGTTTTCAGCTCTGGTCGCGCTCAAGAAGCATCGACGTTATCATACGGGCGAGAAACCATACACCTGCACTGTGTGTAGCCAATCTTTTGCCGTCAAGGAGGTGCTTAATCGTCACATGAAGCGGCACACGGGCGAGCGTCCGCACAAGTGCAACGAGTGCGGCAAGAGCTTTATACAGGCCACACAGCTGCGCACCCATTCCAAGACGCATCTGCGTCCCTATGCGTGCTCCTTGTGCATCCAAAAGTTCAAAACAGAGAAGCAACTCGAGCGCCACGTGAAGGATCATACGCGCCAGAAACGCGCCTCCTTTGCCTGCACGGAGTGCACACGAAGTTTCCGCACCAGCGCGCTGCTCAAGGAGCACCTGGATGCTGGCGATCATTCGCCTGTTAAATCGACACGAGCCAAGCGCTCGGCCAAAATGATCGAGCGCACGGACTGCGCCATTTGCGACAAGAACTTCGACACAACCGAGACACTCCGGAATCATATACGCAGCGTGCACGAGTGCGATCCGGATGACATCTTTGGCACGGAGCCGCCAGCCAAGCGTAAGGCTAAAAAGACCGTCGTGGCCGCGGTAGCGGAGGAGCAGAAAGAGCAGGAGGATGACGTGCCGGCGGCCAACACGTCTGCGGGCTCGCTCATCTCCAGCAAAACGGATGGCAACGGAGTCGTGGTGCGCGAGTTTCTGGTGGATGAGGGCGATGGCAACGCGCAGACCATTGTCCTCGAAAACGAGGTCTACACCATTTTGCCGCTGGAGGGTGACAAGGCAACCGAGTCCACGGCCGAGACCGACGTCAAGGCCGAGTCGTCTAAGGAGAAGCCATCTGTGTCGCCGGTGGTCAAGAAGGAGCAGCGAAAATCACTGGCCGCCAGCTTGGCCGCTGCCATTGCGGATAATCTGGAGGAGCCGTCGAGCGATGATGAGTTCAGTGGCGAGGTGCTGACCGAGGAGGATCTGAAGCTCAAGGAGAACATTGCCAAGTTAATCGACATGCTGGTCGATCCGCAAACCCTCAAGAAATACGGCTGGCCCAACAGCTCCGAGGAGTCGGTACTGTGCAAGGTCATTGAGAACTGTGGCCACGATCTGGCCAAGGGCAGCGAAGCCTACGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGCAAACTGCTCTTCACCGTGGTGATTCACAATGATTCGATAAAGGCGCTGCTCAATAATTTCCCGATCGACGATGTTATTGAGTATGTGCTGGGCGATGAGGATCAGGACCAGGATCAGGAGACAGACAAGGGCAAAGACAGGGAGGCCGAcaacacggacacggacaccaGAGAGGATGCTGTTGAGTCCGAGGCTTAA
Protein Sequence: MIQIVQLKNLLNFKSRTSNEIRNASDKTTPGHTNVSTADCLSTKSVNSPTLTPLCTLTCLCSSCEFILARHSMSASKDALPATPPASSSIKISDGDKPKEKRTGTRMKLLNDVAAKAAVASKGASVSPRLKPEKRTSIKILNNNNNDEAQTSTKGGDRRATPKAASTSVKILNEKRSAPASSAVETAKIKTSPSKKKKMDHYVLQAIKSENNKAENTTSVVVVEDEDTIDFILADDEVELGAGAKENGEEFVVSGVDEDDDDDDDDEDEGVVEGGAKRRSGNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSGALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYACSLCIQKFKTEKQLERHVKDHTRQKRASFACTECTRSFRTSALLKEHLDAGDHSPVKSTRAKRSAKMIERTDCAICDKNFDTTETLRNHIRSVHECDPDDIFGTEPPAKRKAKKTVVAAVAEEQKEQEDDVPAANTSAGSLISSKTDGNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGDKATESTAETDVKAESSKEKPSVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDEFSGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDQETDKGKDREADNTDTDTREDAVESEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00495995;
90% Identity: iTF_00506253;
80% Identity: -