Basic Information

Insect: Drosophila villosipedis
Gene Symbol: -
Assembly: GCA_035043025.1
Location: JAWNNF010000023.1:8963712-8976879[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.7 1.7e+02 2.8 2.3 3 23 305 327 303 327 0.92

2 14 3.1 2e+02 2.6 0.1 3 21 468 486 467 490 0.91

3 14 0.11 7.1 7.2 0.3 2 23 512 534 511 534 0.94

4 14 0.047 3 8.3 0.6 1 23 551 574 551 574 0.95

5 14 0.16 10 6.7 0.2 1 21 579 599 579 603 0.91

6 14 0.0069 0.44 11.0 0.1 2 23 661 683 660 683 0.95

7 14 0.68 44 4.7 0.2 1 21 688 708 688 708 0.92

8 14 0.013 0.82 10.1 1.6 2 23 771 791 770 791 0.91

9 14 3.3e-05 0.0021 18.3 0.8 1 23 797 820 797 820 0.97

10 14 0.00028 0.018 15.3 0.4 1 23 846 868 846 868 0.98

11 14 1.2 75 4.0 0.4 1 23 875 899 875 899 0.95

12 14 0.5 32 5.1 5.9 1 23 904 928 904 928 0.97

13 14 0.0017 0.11 12.9 2.2 2 23 942 963 941 963 0.96

14 14 0.0012 0.079 13.3 3.4 1 20 969 988 969 990 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.7	1.7e+02	2.8	2.3	3	23	305	327	303	327	0.92
2	14	3.1	2e+02	2.6	0.1	3	21	468	486	467	490	0.91
3	14	0.11	7.1	7.2	0.3	2	23	512	534	511	534	0.94
4	14	0.047	3	8.3	0.6	1	23	551	574	551	574	0.95
5	14	0.16	10	6.7	0.2	1	21	579	599	579	603	0.91
6	14	0.0069	0.44	11.0	0.1	2	23	661	683	660	683	0.95
7	14	0.68	44	4.7	0.2	1	21	688	708	688	708	0.92
8	14	0.013	0.82	10.1	1.6	2	23	771	791	770	791	0.91
9	14	3.3e-05	0.0021	18.3	0.8	1	23	797	820	797	820	0.97
10	14	0.00028	0.018	15.3	0.4	1	23	846	868	846	868	0.98
11	14	1.2	75	4.0	0.4	1	23	875	899	875	899	0.95
12	14	0.5	32	5.1	5.9	1	23	904	928	904	928	0.97
13	14	0.0017	0.11	12.9	2.2	2	23	942	963	941	963	0.96
14	14	0.0012	0.079	13.3	3.4	1	20	969	988	969	990	0.95

Sequence Information

Coding Sequence: ATGAACACCGAGTCGACAGATTTGGAGGACACGCATTTGTGCATCAAGTGCAATGCGACAATTGTGGGTCTGAGCAAGTATATTGAGCACCGTAAACGGAGTTGCCTCAGCACTGGCGGCAATGAGCACCTGTCGAAGCAGGTGGTGACTCCGGCAACGACGTCGGCTGCCACCGAACAAGTATCGCACTCAGGCATGCGTCGCAGCAACTTGGACCATACCTATGACGGCTTCCACTTTGCAGAGCCGGAGGCACCCAGCAGTTATCTGCGCAAAACGGCCTCCAGTCATGGCGGAAAGACGTCCAAGTCCCTAACGGATTCCTATGATCCGACGTACGAGCTGGGTGCCGATCTGTTCTTCTcatcgctgcagctgcaaagtGTATCAACTGGCGGCAAGACAGGTGCACGGCCCGAGCGTGGCGCTAAGGAGGAGCAGAGCTGGCATACGTCCAGCAACTGCTCCGATCCGCTACTGAAATTGGTCCGGGAACACGAAGTAACCCACTTTAAGTCACTCAAATTTGTGCACTCGCCGGAGGCAAGCGAGgatgaagacgacgacgaggactTCGagggcgatgatgatgagcatgAGCATGAACAGGAACATGATCCCGATCCTGATCCTGATCCTGAGCCTGATGAGGATTACGATGGGCGTCGCCATTCGCCACCGACGGTGCCAGCCACGCACACTGGTGGCAAATGGAAGCCAGAGCATCGTCCGCAAATGCAACACACTCACCTCGAACGCATCTCGCCCAGCTGGGATGAGCCGCCCGAGGAACAACACGATCATCCGCCGGCGGAGCACACGCACGGCAAATGGGTGccaggcagcaagcagctgGAGTATCGCGAGAACATCGATCTGACCAAGTTGCAGCAGCCAGACGCCAGCTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCGCCTCAACTACGAGCAGCATCTGCGCAGCGCCTACCATCAGCGACGCGCCGATGCCGAGCGCCAACTGGAGCAGGCCAATCTCGCAAGCGCCAATCTAACACTAACCACCAAGGACTTTCCACAGATGCCGTCGACGGAGCAGCTGCCGcggcgtcgccgtcgtcgtgcCCACTTTCTGCGCTGCGATCTGTGCCGGCACAGCATGGCCCGTCATCTGATGGGCAAGCATCTCATCTCGCACTATCACTATcgccggctgcagcagcagcaaccgaaCCAACTGCGCCGACAGAGCGCCCTGCATGACATCCTGGAGCACATGGGCAGCATTGTGAGACAGGCGCCATTCCAGTGTCTGCCCTGTCGCTTCTATGCCAACACTGAGCAATCTTTTCAGCTCCATTGGCGCTCCTCGACGCACGTGACGCTGACGGAGCGACTTGGTGGCAGCTTCTGGTGCAGCTACTGCCAGTTCGAGAGTGCCAGCAATGAGGAGAtgtggcaacatttgctgGGCTCCACGCACAAGGAGGTGCTCTTTGCGATCAATCGTTCGGTGCCCGTTTGCATTGCCCAGCGTCGTCCACTGAGCTGTTCCAGCTGCAGCGCCAGTTTCCTGTACAATGCGCAGCTGCGTCGTCACCTCGCCTCGGAGCATGTGGAATTGGTGGTAGCGGGCAGCGCTGCCGATGATTATCAGTGTCGCTTTCGCTGTGGCATTTGTGGCGTTGCGCAGAGATCTCGAGTGGCGCTGCAGCGGCACGAGAAGCACCAGCATCGATTGGCCAAATACTATTGTGCCGTTTGTCGGCTGGAGTTTGAGACGCCGCAGGAGGCGCGACGCCATCGCAGCCTAATGCAGCACAAGCGGCGAGCTTCCCGCCAACTGAGccgcaaatgcagcagcagcagcagcagtaatcaGCCGGATCGCGAGATTCAACACATGCTGCACGAGGTgctggaggagcagcagccagcagcagcaggagaacaGCCATCAACACTGAGTTCCAATAGGCGACGCCTGACCAGCCAGTGTGTCAGCTGTCCGCTCAGCTTTGAGACGCCTCAGGCACTCGTCCAGCATCGTCGCGAGTTGCATCCGGTGGACAATCATGCCTGTCTCAGCTGTGGCAGTAGCTTTCAATCCGCCCAGGCTCTGGGAAGACACACACGCTGCTGCCAGCCCACAGCGTCCACCTcgacagctgttgctgcttctgctccagctccagctgcaacCTCTGAATCAAAGTCCTGGAACTGTGCGCAGTGCAGTTTCACAGCTCAATATGAATCGGATTTGCTCTATCATCGCTTCTTTCACACCCAGGGCTCGGCAATTGACAAGAATGAGCTGCTCCAGTGTCCGCTGTGCCCCAAACAGTTTCGCAAGCACTCGCTGCTTCCCCATCTGCGCAATCATACGGACGAAAGGATCTTCGAGTGCGTCGAGTGCTCGGCCAAGTTTGCCCGCAGACACAACCTCAAGAATCACATCGCAACAGTGCATGGCCAAAAGGAGAAACCATCGCCAGCTGCTGATAAGTCAACAGTCCAGCAATCGAAAGTGGTTGCAAAGCAGAAATATCAATGTGGCACCTGTGGCAAAATACTGGCTAAAAAATACTCACTGAAACTACACGAAATGAGCCACGCTGAGGTGGAGCGTCAACATCGTTGCCACATCGAGGATTGTCAATATGCTGGTCTCACGCCGGAGGCACTCAAAATCCATCTAATCTCACATGCGAATGGAAGTCACAAATGTGAACACGACAACTGCCAATATGTGGGCAAAAGTGAGCTGCATTTGAAGAGGCACCTCAAGTCGCATGTGCCCGAAAAGGAGCTGATCGAGGATGGCAAATGGTTGCCGTGCGATCAGTGCGAGTTCAGGACCCGCATCAGGGGACATCTGAGGCGGCACATGCGTAGTCACACTGGCGAGAAACCCCATCAGTGTCCGCACTGTGACTTCCAGTGCAGCAGCATGGATAATCTTCGCAAGCACATCGTCAAAACGGGCAAGCATCCGGGCAAGTTCATCTACGAGTGTTCGTCCTGCGACACCTTCAAGAGCAACAGTTTCAAGGATCACCGACTACATTTGGCcacgcataaaaataaattgccctAA
Protein Sequence: MNTESTDLEDTHLCIKCNATIVGLSKYIEHRKRSCLSTGGNEHLSKQVVTPATTSAATEQVSHSGMRRSNLDHTYDGFHFAEPEAPSSYLRKTASSHGGKTSKSLTDSYDPTYELGADLFFSSLQLQSVSTGGKTGARPERGAKEEQSWHTSSNCSDPLLKLVREHEVTHFKSLKFVHSPEASEDEDDDEDFEGDDDEHEHEQEHDPDPDPDPEPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQMQHTHLERISPSWDEPPEEQHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPDASYWCNICCRRLKTRLNYEQHLRSAYHQRRADAERQLEQANLASANLTLTTKDFPQMPSTEQLPRRRRRRAHFLRCDLCRHSMARHLMGKHLISHYHYRRLQQQQPNQLRRQSALHDILEHMGSIVRQAPFQCLPCRFYANTEQSFQLHWRSSTHVTLTERLGGSFWCSYCQFESASNEEMWQHLLGSTHKEVLFAINRSVPVCIAQRRPLSCSSCSASFLYNAQLRRHLASEHVELVVAGSAADDYQCRFRCGICGVAQRSRVALQRHEKHQHRLAKYYCAVCRLEFETPQEARRHRSLMQHKRRASRQLSRKCSSSSSSNQPDREIQHMLHEVLEEQQPAAAGEQPSTLSSNRRRLTSQCVSCPLSFETPQALVQHRRELHPVDNHACLSCGSSFQSAQALGRHTRCCQPTASTSTAVAASAPAPAATSESKSWNCAQCSFTAQYESDLLYHRFFHTQGSAIDKNELLQCPLCPKQFRKHSLLPHLRNHTDERIFECVECSAKFARRHNLKNHIATVHGQKEKPSPAADKSTVQQSKVVAKQKYQCGTCGKILAKKYSLKLHEMSHAEVERQHRCHIEDCQYAGLTPEALKIHLISHANGSHKCEHDNCQYVGKSELHLKRHLKSHVPEKELIEDGKWLPCDQCEFRTRIRGHLRRHMRSHTGEKPHQCPHCDFQCSSMDNLRKHIVKTGKHPGKFIYECSSCDTFKSNSFKDHRLHLATHKNKLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528388;
90% Identity: iTF_00482583;
80% Identity: -