Dvil013222.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila villosipedis
Gene Symbol
Hivep2
Assembly
GCA_035043025.1
Location
JAWNNF010000032.1:10908305-10916817[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0015 0.096 13.1 0.4 2 23 269 290 269 290 0.98
2 8 0.00023 0.015 15.6 3.2 1 21 296 316 296 320 0.90
3 8 0.0091 0.58 10.6 0.4 1 19 980 998 980 1001 0.93
4 8 2.8e-06 0.00018 21.6 2.0 1 23 1754 1776 1754 1776 0.99
5 8 3.1e-05 0.002 18.4 5.3 1 23 1782 1806 1782 1806 0.92
6 8 0.00048 0.03 14.6 2.7 3 23 2279 2299 2278 2299 0.97
7 8 0.00081 0.052 13.9 1.2 1 23 2305 2329 2305 2329 0.91
8 8 0.0026 0.17 12.3 2.7 1 23 2350 2374 2350 2374 0.92

Sequence Information

Coding Sequence
ATGACGCTACAGAAGGTGGCAAGCAGCGCAGCGAgcaatgtggcagcaacaacaacaacagcaacaacaataccagcCACAGccaacaccaccagcaacaataacaacaaccagaacagcagcagcagcaacaacaacaacaacagcagcaacaaccacaacaacaacagcagcagtgaggatccaacaacagcgacagcaacaattgtcGATGGCTGGACGAGCTCAACCAATTTGcgttatttgcacaaaaagttTAAGCGGCTGGCGAGCACCACCGAACCAGAGTCGGTGGATGCAATGGCAGCGGTGCGCACCACATCGCTGTCATCAAACAGCTCGTTATCGCCACCGTTGCCAGTGGCCGCAGCACCGCTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATGTAGAATTCAGTGCCAATTTCGTAAATGCcaacgacaacatcaacaacaacaacaacaataacaataacaacagtcATGatgagagcaacaacagcagcagcaacaagcatggcaatgttgctggtgttgctggtgcgCCTCGAACACGCACGCCCCTCAGCAACagtaatagcaacagcaatattaaCTATGCCAGCAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagtagccgcaataacaacaacaacagcagcagtaacagcagcaacaataatacaaacagcaccagcaacagttgcagtcgcaggaTTGGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCATCGGTGCTGGAGAAGCACATTCGTGCCCATACCAATGAGCGACCGTATCCGTGCAACAACTGTGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGccgttcccgttcccattTGGCGCGCATGCGTGGCATCGATGTGCCAGCCAATGAGACGGACGGCCTGTCCGACCAGGACGGCGATGGGGAgctgagcaacagcagctccgAGCTACTAAGCGTCGAAGTTTTGAGTCGCACAGATTCGCCTTATGATGAGGCAATGGCCTCGCCGACGCCATCACCATCGACGCTGTCGGCGGCGAAGAGTACGTatttgcagcagccgcaactgcaacagcatatgctgcaacagttgccgctgGGCTCACCAGCAGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTACACTCGGCGACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCATCCCTCTATGCGCCCGGCACTCtcaaggagcaacagcagcaacaacaacagcaacagcagcagcagcaggtactgcaacagcaacagcagcaggcgttgctgcaaccacaacagcagcaacacaaactatcagcgcagcaacagcagcagcagcagcaaccatcGCTGGCGCATCCAACGCTCTCGCCCAGCACCCAGTTGAAGCTCAACAATCACATCAATTCGCatcagttgcaactgcagctgcagcaccagcaccaacagcagcagcagcaacagcatttgcACGCCCAGCAATCCTTGCTGCTGGCGGCTGCAGCAACCAATCCGGTTGCATTGTCTGCattgccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAGCATGCGTTGGCCATTCAgcagatgcagttgcagcagcactttcagctgcaacaacagcagcagcaacaacagcagcagcaacagcagcagcagcatcaccaacagcagcaacagcaacagcagcagcagcagcatcaccaacagcagcagcagcaacactcgcCGTTGCTGAAggcgccacagcagcaacagcagcagCTGTTGCGCTCCACTAGccaacaacaggcagcagtgattgcaacaacagcagcgctgCCAGCACCAGCCACACCCAACCCGCCAACCAATCTGAGCAGCTTTGCCAGCTCAAGCGGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTTATCTCACAGAACGAGGCGATTGTGGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaacagcaacaacaacaatagcagcaacagcaacatcaacagcagcagcagtatacCAACAACAGCGcacgccaacagcaacagtaacaacaacaacagcaatcagcaGCTGGGCGAGACTAAAGTGAACCTAGCACAGGCCATAgtacaaaaacagcagcaacagcaacaacagcagcatatgcaacaacagttgcagcagcaacagtaccAATTatacttgcaacagcaacaacaactggatcCGCCTGTGAATGGTCTGCtgaagcgcagcagcagcagctctgcAAGCAGTACAGCCAGCAGCGGCTATGTCAGCCTTAAGGGCACAGGGACCCCAACACTAACCGCCGCAGCCactgtaaatataaaacagttgcaacagttgccgccgccgccatcgccgttgccgttgcaacagttgcagtatCGCCAGGATCCGTCAACGCCAGTGCCcaagctggagcagcagcagcagcagcagttgcagcaacccTTGCCGCTGAATTTGTCTGCCAAGCCCAAGCCGTCGCTAGCAATGCCAGCAAAACcaacgccaacagcaacagcagccgcagccgcatcagcaacaacaactgttgttgccaagagcacaacaacaacagcgccagCGGCTGTATCGAATATATCCATAATCAAGAATCTGCTGTTGAATGCACGTGGCCTGGCAGTTCCAATTGGCGAGGGCGATGATGCCGTCTACTCCTGCCCCATTTGCGCCAGTAAGTTTCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTACTGCCAGGATGCGAACAGCAGTGCACCGATCAGTCCAGCCTCATCGCCGAGCACCAAATACTTTCGCTCCAATTCCATATCGTTTAGCCTGCCAGAGCTCCAATCGCACATGGCCAACTCGAAAAATCCGTTGTCGCTGGCCAAGCTCGCCAAGGTTGCCTGGTCGCAGCTAAAAACCAAGCCGAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCGCAATCTCCCGCACGCACCTCAACCGTCACAGCGgctatcaacagcagcagcagcagcagtagcagcagcaaccacataaacagcagcagcagcatcaataacaacaacagcagcaatcacataccagcaacagctgttgtaATCCCGCCCAGCATTGATGCCACCAGCGTTTCTTTGCGTTTTGTGGACGCACCGCTGCCGTCGCCGGGTCCGCTGCTCGGCAAGACACCGTTGGTGGATTATGCGGCGCCACGTAAAGCGCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCCTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAGATGAGCAGTGGCGAGACATCGTTCACGCTGCCATCTGTCGTCGATATGTTCTTTGTTGGCAATCCAGAGTTGCAGTTCAGTGGCAAGGATGAGCGTTTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCGGAGTGTCCCGAGCTGGACAAGAGTCCCAAAATGATACGCACTCCTCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCACGTCTCAGCGACATCAAGGAGCGCAAACTACtcgctgccaacaacaataacaacaaccacaacaacaacaataagaacaataataataataatggtttCCTGCTCAGCGGCTCCAACACGCCGCATCATTTCCAATTCCCACCAATCAATTCGATAACCGCCTTCAATCCGCTCACCCTGCCACCCATGAGCAACAGCAtcggcaccagcagcagcagcaacattgtgGATAAAGCGATACCCCATGTGCCGGGCATACCCGGTCCGGGCAGCTTATCGTTGTTGCCACCgccactgcagctgcagcgtgGGCGCAGCCCCAATCGCAAACAGCCCAGTCCCAATACGAATGCCAATCTCAATATCAATCTCAATCCGCTGCTGGCAGCTGAGGGCCCACTCAAGGCACTCTCACCCTTCGGTGGCGTACAGAATTTGCCCAGCGAATTCAGTCGCCAACCACCAACGCCAGCGCAACGCAATGCGCTCCAATggacgaacagcagcagcaataagctGCCAGTGATTGTGGCTGACGGCACGCTGGCCAAGAAGCCACCATTCAATTTTCTACGCATGGCGGATAATGTGAAGAGCTCCGCTgtgcaggagcaacagcaacaggcccAGCCACCGGCAATGGGTATGCTGGAGGTGCGTCACTTCAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCACGTCGACACGCCCGatgaggcagcagcagtagcagcagcagcaatcaaaacaataacagcaaccaCTGCAATTCTAGTAGCTGCAACAAGCGCAACGAGCAGTGCCAAGTCGAAATTCTTGCGACCCACCAGTCTGCCCCTAAAGCCGGGCACCTTTACCCCAAAGCGACATCATGGCATCACACCGACTGCCAATACACTGCCCCTCATCTCGCCGGAAACCCCGAGACCCTCCAAGTCGTGCGTGCAACTCTATCTGAATGGCCATGCGTACACCTATCTGGGACTCAAGTGCAGCACGAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGTTTCAAGCCCAAACAGGTGATGGCTCTCTACGATTCCAGGCAAAAGATGCTCGGCTCTGGTTATACCACAGCAATGGCGGGTGCCGGCAAACTGCAGTATTCTGTCTTCAGTTCACAGGAAACGGTTAGCACGTGCTCAACGACGGCCAATGGACAGAGCAAGTTCTACCAGCACCAGTTGAAACAGCCGCCGGCAATTGGCGCGCTCAGCGAAGCGAATGTGGCAGCCAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAAACGGGTCAACTATTGGTCGGTGGCTACGAGTCGCACGAGGATTACACGTACATTCGTGGACGGGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCATCCATGCTCAAGAAGCATATACGCACCCACACCGATGTCCGTCCATTTACCTGCAGTCACTGCAGTTTCAGCTTCAAGACCAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAATGCCAAGAGCTGGGCATCAATCCGGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGTATGAAGGAACATGAGGCGGCACGGGgtctgctgtcgctgtcgatGACGCCGCCGATACCGCAGAGTATTTCTCCGTATCCGGCACTGGTTCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCCTCGGCTGGCAGCGCAGCTGGCAGCGGCTCGCAGCCGAAGCGACAGGTTTGCTCGTTTACGTCGCCCAAGCCGCCGTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAACCTAAGCGCGGTGTGCCCAACGATGAGAGCAGCGCACCCATGGATCTGACCAAGCCACGTCCAATGCCCAGCATTTCAGTGGCGGCCTCGTCGCCTGTAGCTGACCAGATGCTGGCCCAGACACCCAAATCGCAGGCACAGCAGATGCGTGACGTAATCTTTGGCACGGGCAACAACGAGTGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGACAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCAAAGCGCGAAAGCGAGGGCGAAGATGTCCTCCTGCAGGCGTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGTCGCAGCTACCTGGTCACTTCCACCACCAACTCCAACGCGAactgcatcagcagctgcagctccaacTCGACCACGAGCAGCGTTAGCATTAGCTGTGCTGTGACCACGCCCATTGTTAATAGCAAGCCACAGTTGAACATCGCTGAATTGCCCAGCATTGAGGTGCACGAGGTGAAGACACCAGAGTCGCCAACGCCATCGCCGGCACTTGTCAAATCCGCCGAGGAGAGTGAGGAAAGTGAAACACAATCGGATCAGGAGAAGCCGAGCCTAACAACATCCATCCCTGTACCAGTAACCGTCTCTGTCTCAGCCTCTGTACCCGTTTCTAGCTCCAAGTCGAGTGCAGATATTCAGCAGCCGCACAATGCCAATTTGCCtgctgcagtgcagcagcCAGATGCCACCGATTTTAGTGGTgtactcagcagcagcaacagcaacagcaatagcaacaaaaatagcaacagcagcagcggcagcagtggATCAAGTGCACCCACGCGTATTGTGGTCGTCGGTGAGGATGGCTTCAAAACGACACAAACCAGCGGCAGCAACGAATTGCAGTCTGCTGGCGgcgcaacaacagctgcaacagcagcggcaacagcaggtGCAACGTATACGAATCGTGTggtgccaccgccaccgccgccaatAGCGAGTGATGCACGACCCATTTGTACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGTTGTCGCTGCACATGAACATCCACTACATGGAACGGAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACCCAGGGTCACCTGCAGAAGCACGAGAGGAGCGAGGCGCACCGCAACAAAGTGATGATGACATCAACGTTTGGTGTGCCAACCACATCCAATCCGCGTCCGTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACACACGTGCAGAAGTTGGAGTGCCTGCAGAAGTTGCCATTTGGCACCTATGCCGAGATCGAACGGGCTGGCATCAGTCTGACGGAGATCGATACCAGCGACTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCACAGAAGCTGCTCGAGAAGGATCCGAACAAGTTGAGTGGCTACACAACGCCATCGGGCATGCTGCAGCTATCGGCGGATGCACCGGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCAAACAGTGCCGCTGCTTCGGCCATTGCCTCGCTGGACAACGACAGTGCTGGCAACACACCGAAGCGTGCCAGCTCCATGTCCGAGGATGAGACGCTCACCAACGGAGTCGGCctcagtcacagtcacagccatGGCCACAGTCTGAAGCGGCGTCTACAGAAcagcagcttcagcagcaATGGCGATGAGAGCGACAATCCAACGGATACCActggcagcggcagtggcagtggcagcagcgagAAGCGTGCCAGAAGCAACACCAATGAAATCATCACACTGCCAACGCCGGTGGCTGTGTCGACGGCAACGGCCAGCAACTGa
Protein Sequence
MTLQKVASSAASNVAATTTTATTIPATANTTSNNNNNQNSSSSNNNNNSSNNHNNNSSSEDPTTATATIVDGWTSSTNLRYLHKKFKRLASTTEPESVDAMAAVRTTSLSSNSSLSPPLPVAAAPLLNGHVTVKVAPLLPARNVEFSANFVNANDNINNNNNNNNNNSHDESNNSSSNKHGNVAGVAGAPRTRTPLSNSNSNSNINYASNATLSPATFAQHQQQTQPTPAATVAAITTTTAAVTAATIIQTAPATVAVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGIDVPANETDGLSDQDGDGELSNSSSELLSVEVLSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQHRQSLDYKPYKPKFHNASLYAPGTLKEQQQQQQQQQQQQQVLQQQQQQALLQPQQQQHKLSAQQQQQQQQPSLAHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQQQQQQQQQQHHQQQQQQQQQQQHHQQQQQQHSPLLKAPQQQQQQLLRSTSQQQAAVIATTAALPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNSNNNNSSNSNINSSSSIPTTAHANSNSNNNNSNQQLGETKVNLAQAIVQKQQQQQQQQHMQQQLQQQQYQLYLQQQQQLDPPVNGLLKRSSSSSASSTASSGYVSLKGTGTPTLTAAATVNIKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQQQQQLQQPLPLNLSAKPKPSLAMPAKPTPTATAAAAASATTTVVAKSTTTTAPAAVSNISIIKNLLLNARGLAVPIGEGDDAVYSCPICASKFRSADELKHHNSTYCQDANSSAPISPASSPSTKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAAINSSSSSSSSSNHINSSSSINNNNSSNHIPATAVVIPPSIDATSVSLRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKMSSGETSFTLPSVVDMFFVGNPELQFSGKDERLRRFTSSGGTMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSDIKERKLLAANNNNNNHNNNNKNNNNNNGFLLSGSNTPHHFQFPPINSITAFNPLTLPPMSNSIGTSSSSNIVDKAIPHVPGIPGPGSLSLLPPPLQLQRGRSPNRKQPSPNTNANLNINLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNSSSNKLPVIVADGTLAKKPPFNFLRMADNVKSSAVQEQQQQAQPPAMGMLEVRHFNFDNVNKSQEALAPLHVDTPDEAAAVAAAAIKTITATTAILVAATSATSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGSGYTTAMAGAGKLQYSVFSSQETVSTCSTTANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCSFSFKTKGNLTKHMQSKTHFKKCQELGINPGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSISPYPALVQDTPAASPANSIGSSAGSAAGSGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVADQMLAQTPKSQAQQMRDVIFGTGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQAYIKEQALQHAKMKQSQFSRSYLVTSTTNSNANCISSCSSNSTTSSVSISCAVTTPIVNSKPQLNIAELPSIEVHEVKTPESPTPSPALVKSAEESEESETQSDQEKPSLTTSIPVPVTVSVSASVPVSSSKSSADIQQPHNANLPAAVQQPDATDFSGVLSSSNSNSNSNKNSNSSSGSSGSSAPTRIVVVGEDGFKTTQTSGSNELQSAGGATTAATAAATAGATYTNRVVPPPPPPIASDARPICTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGVGLSHSHSHGHSLKRRLQNSSFSSNGDESDNPTDTTGSGSGSGSSEKRARSNTNEIITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00513682;
90% Identity
iTF_00499804;
80% Identity
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