Basic Information

Insect: Drosophila varians
Gene Symbol: -
Assembly: GCA_018150405.1
Location: JAECWK010000015.1:21290671-21295196[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.067 6.3 7.2 2.7 1 21 202 222 202 224 0.89

2 18 0.02 1.9 8.9 1.4 1 23 230 252 230 252 0.97

3 18 0.11 11 6.6 1.9 2 23 284 305 283 305 0.95

4 18 2.3e-05 0.0022 18.1 0.3 1 23 378 401 378 401 0.94

5 18 2.3 2.2e+02 2.4 0.2 3 23 474 494 472 494 0.92

6 18 1.2 1.2e+02 3.3 1.9 1 23 572 595 572 595 0.92

7 18 0.13 12 6.4 0.3 1 21 604 624 604 625 0.90

8 18 0.00022 0.021 15.0 2.4 2 23 680 701 679 701 0.97

9 18 3.4e-06 0.00032 20.8 6.7 1 23 707 729 707 729 0.99

10 18 2.3 2.1e+02 2.4 4.9 1 23 870 893 870 893 0.93

11 18 0.18 17 5.9 0.9 1 21 900 920 900 921 0.92

12 18 0.004 0.38 11.1 1.3 1 23 930 953 930 953 0.97

13 18 0.0027 0.26 11.6 1.2 2 19 974 991 973 995 0.94

14 18 0.0001 0.0098 16.1 0.5 1 23 1002 1024 1002 1024 0.98

15 18 4.5 4.2e+02 1.5 0.1 2 21 1051 1070 1050 1071 0.90

16 18 0.025 2.4 8.6 5.0 1 23 1116 1139 1116 1139 0.96

17 18 0.0064 0.6 10.5 0.3 1 23 1176 1199 1176 1199 0.97

18 18 0.00016 0.015 15.5 1.5 1 23 1227 1250 1227 1250 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.067	6.3	7.2	2.7	1	21	202	222	202	224	0.89
2	18	0.02	1.9	8.9	1.4	1	23	230	252	230	252	0.97
3	18	0.11	11	6.6	1.9	2	23	284	305	283	305	0.95
4	18	2.3e-05	0.0022	18.1	0.3	1	23	378	401	378	401	0.94
5	18	2.3	2.2e+02	2.4	0.2	3	23	474	494	472	494	0.92
6	18	1.2	1.2e+02	3.3	1.9	1	23	572	595	572	595	0.92
7	18	0.13	12	6.4	0.3	1	21	604	624	604	625	0.90
8	18	0.00022	0.021	15.0	2.4	2	23	680	701	679	701	0.97
9	18	3.4e-06	0.00032	20.8	6.7	1	23	707	729	707	729	0.99
10	18	2.3	2.1e+02	2.4	4.9	1	23	870	893	870	893	0.93
11	18	0.18	17	5.9	0.9	1	21	900	920	900	921	0.92
12	18	0.004	0.38	11.1	1.3	1	23	930	953	930	953	0.97
13	18	0.0027	0.26	11.6	1.2	2	19	974	991	973	995	0.94
14	18	0.0001	0.0098	16.1	0.5	1	23	1002	1024	1002	1024	0.98
15	18	4.5	4.2e+02	1.5	0.1	2	21	1051	1070	1050	1071	0.90
16	18	0.025	2.4	8.6	5.0	1	23	1116	1139	1116	1139	0.96
17	18	0.0064	0.6	10.5	0.3	1	23	1176	1199	1176	1199	0.97
18	18	0.00016	0.015	15.5	1.5	1	23	1227	1250	1227	1250	0.97

Sequence Information

Coding Sequence: ATGCTACCACCAAACACTTGCCGAACTTGCGCGGAGCAAAATGCCGACTTGCAGCCGCTTTCCGCTTGTTTGGAAAAAGAAACCAATAAGAGCTTCTACGAGATTCTCCACGAGTTGACGCAAATCGATGAGAGCTTGGACGCCAGCCTACCTCAGCATTTGTGCACCGATTGCTTGAAGAGATTGGAGAACGCCTATGCCTTTGTTCAGCAGGCCAGAAAAGTTAATGGAGAACTTTTGGTGCGGCTGAGAGAATGCCTTGATGAGACGCCCATAGACATACCCCAGGAACAGCAAATAAAAACGGAAATAGAAGCTGATGCAGATAACGATAATGTGGTTGAAGAGTCACTGGGCATTTCTTCTGTTGAGTGCAAGTGGAATGAGGAAAGCGACAGCGATACGAAACATCCTGAGGCTGCCACCGAAGCGGAGGAAGTCGATGAAAAGCCGTATCAACTAAGAAGAAGCGCCCGGAAAGTAAAGCCGCAAACAGACAGTGAAATCGAGGAACTCAGCCTCGGTGAGCTATCGCCTTTAAAACGACGGCGTGGGCGACCTCCAGGTCGGGCGAAGAGCCAATCTTTGACCCCCGACGGCCGGTATGCCTGTCGAGTATGCGGCAAAAGCTTCTCCTGGTACCGCGACATGCAGCGGCACTCACGGTGTCATTTTGACAAAAATGCCTATGTGTGCAAATCTTGTGGAAAGGGATTTCTACGTAGGGACAACTATTTGTTTCATCTCCGCAGTCATGACAAAAAATTGGCCAAACAAGAGGCCCTAAAGCTGAGAAATGAATGGCTCTTTGCCGACCGTTTGTACTCCTCCGGGAAGCTTAAAAAAATACAATGCAAACTATGCAATCAAAAGTTTCAACGCACTGAGGATCTCATATGTCATATTGACAGTCACATGGCCTTAGATAGTTTAAGCACCATTACTCTGGATAACGACGTGGTCCGAGAGCATTATCATGCACAGTCTGGTGACTTGGACAGCATCAAGCATATGATTATAACTGATATAGCCCAGGGAATTGTGGAAAAGTTTGCTTCCGTTGTCAACTTCCATGGTTACGAGATGGATATCAATGACTCGGAAGAGGAATCCCCCCCTGACACTTCGAAATACGTTTGCGATATGTGCGATGAGGGATTCGCTCGCCAACACCAGCTGGTGAGGCACACGCTGGAGGAACATGCGCGGGGATCGACGGATGAGCTTCCCTGGCAACGTTGCAGCTTCTGCAAAATCGGATTTCTGTGCTCGGCTGTCTACAATCGGCATTTGCAACACCACTGCCACAACAAGTTAAAGAAATATCACTGTCGAAAATGTCCTGGGAAGTTCATGTGGTTGGATAATCTCGACTCTCACGCCTGCTCACATCGAACTAGCCAAGGTCGTCAAATATTCTGCACTTTGTGCGACGCTCACATGCCTACCTTAGTGGAGCTGCGCAATCACCTGGTTGAGCACCAAAAGGATTTAAAAAACTTCAATCCGGATCCCCGGTCTACTTTCTTCCAAACTTTCTATTCCAATGGCTTGGAATGCACTCCCTCGGAACTAAGTGCTCGTATTATTGAAGATTTTGAGGTTCAAGATATGGAACGCTATTATAATGCTGCCACCTTCAGTGGTCGCGAGCTAGACATTTTCGACTCTGAAACTGAAGTATCTCAAGCAGAAGATGGCTGTGCTCCACAGCATACTTGTATACTTTGTGGGAAAATGTCAAAACGGCTTTTAGTCCTGCTGCAGCACCAGAAAAGCTTTCATTCCGAAGAACTTAGCGCCGTGCCTTTCGTTTGCGAAGACTGTGATGAAGGATTTGTTTGCGAGGCGTTGGTCCAAAAGCACCGTAGGCGATGTGCCGCAAGAAAAAAATCAATGTTCCTTTGCCGCAGCTGCAATCTACACTTTTTATGGCAAAACAATTACGAAAACCACATAAAAGCACACCACGACCAGGAGCAGAGCCCGGAATCGGTAGAAAGTCCTTCCAGACCATGTTCCTCGTCAAGCAAGCTGCAGTGTGATGAGTGTGATAAGACTTTTATTTGGCACAAGGACCTCACCCGCCACAAGCGCATGCACCAGACAGAAGTAAAGTTTAAGTGTAATCACTGTGATCGCAAATTTCACCGCAAGGATGGCCTTAAGTCGCACATGCGGGTGCATGCGGCAGTTGAGCAACAAGCGGATCAAACATCAAAGCATTCACTAAATTGCGGTGAAGTTGCTCCTGACATTTTGGTGCAGCTGAGTCGCCCACATGGCTGCAAACAGATCCAATGCATGATCTGCCTGTCCCGTCACACAAAAATTTCAGATCTTCGGGCGCACCTTGCATCCCACAAGTATGATGTGACTTTTTCCGAAAATAGAGATATTACTAGCGTATCAAAAGGTGTTTATCCAGAGCTATCTACGCCTTTGGACAGACACGAACTGGCGAAGAAAATAATGATTGATGTGGAAAAAGGATGCGACCTAGACAGATTCACTTCTATAACAAACGAAGCTGGTTTAGAATTGACTCTAGAAAGCAGTGAGACGGATACGGAGTCCGAACAAGAAGAAGAACATTCCACGCGTATCTATAACTGTCACATCTGTGCAATACAGGTGAAGCGAAAACACAGGTTGTATGCCCACCACTTGGAAAAGCATAAGAAGGAAGATGGTGCCTTTGCTTGCTCCCAATGCCAGACAAGGTTTCTTGATAAAGCCCTTCTGGAACACCACAACAAAACTATTTGCAACAATTCCCAGAAACGCTTCCAGTGCCGCAAGTGTCCGTTACGCTTTCGCTGGCGCGAGAACCTAAAGCTGCATACCAATGTGAACCATCAGCAGGTGGAGAGCATAGCTGAGGGAGAAAATGCTCCGACACAGAGCGATGGAGATCTACACTGTGGAGTTTGCCAGCGTAGCTTTAAAATGCAGAAGGATCTTACGCGACACAACTGGATGCACACCCAAGAATCTAATATATACAGGTGCCGATGGTGTGCCCGCCGCTTCTACCGTTGGGCTAACCTCCTTCAGCATATTGTACGACATGGAATTCGGGCCAATCAATTGCCCTATGCAGAGGCTCTTCTTGACTCGTACGGACATCCCGGAGGTACCAAGGTCATCGAATGTCGCGTGTGCTGCGCAACTTTTCCTACGATTGCGGCCCTGCGTTCCCATCTTGAAAGTAGCCCAGCAGGCAGTCACCACGAGCTTTCGTCGCTCCAGAACTACTCCATAACCAATCAGATGGGCTATGAGCTAACTCTGGAGGATTCTGAGACGGATGAGGACTGTAAGCCACCAGGAGTTCCAGCTTATTACACATGCAGCATGTGCCACCTGCGGTGTGTTCGTAAATTCGAAATGCAGCAGCATCAGCAGGCCATGCACCGCCTTGAAAAGATTTCCGAAGGCTGCAATCACTGCATATTTAAGAGTGTATGCCCGGAGCTAATTGCCCACCATGTACGGACACAGTGTGGCAATCTGGAGAAGCATTTTACTTGTGCACGTTGCGGGTACAAGTTTATGTGGGAGTCAAATTTGTTGCTCCACATGCAGATTCAGCACCAGAAGCAGGAGGATACGGAACTGGATTCTGCCATTCTGGAATCCCCCGATGAACCGACGAACAAAGCTACCTGCCAAATTTTTCAGTGTGGCCTTTGCCCGAGAAAGTACAATCGAAAGGATCGACTGACGGCGCACGTCAAAAAGTTCCACGGACCGAATGTGGAGAAGACACCCAACCGGCCACCTGGGACCGCTTTAAAGAATCACCGCCTGCAACAAGGCCACCATGAAGAAAGCGACACTATCCAGGGCTCGGCACCTGGAGAACCCATTAGACGTACAGTCCTAGAAAACTTTACAGCCTAA
Protein Sequence: MLPPNTCRTCAEQNADLQPLSACLEKETNKSFYEILHELTQIDESLDASLPQHLCTDCLKRLENAYAFVQQARKVNGELLVRLRECLDETPIDIPQEQQIKTEIEADADNDNVVEESLGISSVECKWNEESDSDTKHPEAATEAEEVDEKPYQLRRSARKVKPQTDSEIEELSLGELSPLKRRRGRPPGRAKSQSLTPDGRYACRVCGKSFSWYRDMQRHSRCHFDKNAYVCKSCGKGFLRRDNYLFHLRSHDKKLAKQEALKLRNEWLFADRLYSSGKLKKIQCKLCNQKFQRTEDLICHIDSHMALDSLSTITLDNDVVREHYHAQSGDLDSIKHMIITDIAQGIVEKFASVVNFHGYEMDINDSEEESPPDTSKYVCDMCDEGFARQHQLVRHTLEEHARGSTDELPWQRCSFCKIGFLCSAVYNRHLQHHCHNKLKKYHCRKCPGKFMWLDNLDSHACSHRTSQGRQIFCTLCDAHMPTLVELRNHLVEHQKDLKNFNPDPRSTFFQTFYSNGLECTPSELSARIIEDFEVQDMERYYNAATFSGRELDIFDSETEVSQAEDGCAPQHTCILCGKMSKRLLVLLQHQKSFHSEELSAVPFVCEDCDEGFVCEALVQKHRRRCAARKKSMFLCRSCNLHFLWQNNYENHIKAHHDQEQSPESVESPSRPCSSSSKLQCDECDKTFIWHKDLTRHKRMHQTEVKFKCNHCDRKFHRKDGLKSHMRVHAAVEQQADQTSKHSLNCGEVAPDILVQLSRPHGCKQIQCMICLSRHTKISDLRAHLASHKYDVTFSENRDITSVSKGVYPELSTPLDRHELAKKIMIDVEKGCDLDRFTSITNEAGLELTLESSETDTESEQEEEHSTRIYNCHICAIQVKRKHRLYAHHLEKHKKEDGAFACSQCQTRFLDKALLEHHNKTICNNSQKRFQCRKCPLRFRWRENLKLHTNVNHQQVESIAEGENAPTQSDGDLHCGVCQRSFKMQKDLTRHNWMHTQESNIYRCRWCARRFYRWANLLQHIVRHGIRANQLPYAEALLDSYGHPGGTKVIECRVCCATFPTIAALRSHLESSPAGSHHELSSLQNYSITNQMGYELTLEDSETDEDCKPPGVPAYYTCSMCHLRCVRKFEMQQHQQAMHRLEKISEGCNHCIFKSVCPELIAHHVRTQCGNLEKHFTCARCGYKFMWESNLLLHMQIQHQKQEDTELDSAILESPDEPTNKATCQIFQCGLCPRKYNRKDRLTAHVKKFHGPNVEKTPNRPPGTALKNHRLQQGHHEESDTIQGSAPGEPIRRTVLENFTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -