Dvar011928.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila varians
Gene Symbol
RREB1
Assembly
GCA_018150405.1
Location
JAECWK010000126.1:10306073-10312505[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0035 0.33 11.3 0.6 1 21 252 272 252 274 0.96
2 11 0.0002 0.019 15.2 0.2 1 23 284 306 284 306 0.98
3 11 4.8e-05 0.0045 17.2 7.3 1 23 312 334 312 334 0.98
4 11 1.2 1.2e+02 3.3 3.7 2 19 519 536 519 538 0.97
5 11 0.014 1.3 9.4 0.1 1 23 686 708 686 708 0.97
6 11 0.0018 0.17 12.2 2.0 1 23 1055 1078 1055 1078 0.95
7 11 5.1e-05 0.0048 17.1 0.3 2 23 1400 1421 1399 1421 0.97
8 11 0.086 8.1 6.9 6.3 1 23 1427 1450 1427 1450 0.97
9 11 0.98 93 3.6 2.1 1 23 1577 1600 1577 1600 0.91
10 11 0.005 0.47 10.8 0.5 3 23 1661 1681 1659 1681 0.96
11 11 0.00082 0.078 13.3 4.8 1 23 1687 1709 1687 1709 0.99

Sequence Information

Coding Sequence
ATGCTGGCAGCACAGCAACAGCACAACCCCACAACCAGCACCCCAAACACAAACAGCACAGAAAAGGAGATGGAGCGCCAGAGGCGGGACTCCACCACCTCGGAGTCCTCGCTGGAGCATTTGGATTTGGGGCGCACGCCCAAAAAGCTCAGCGCCGGCAGCGGCAGCGGCGGCTCTCTGCTGCAGCCGACGTCGACGCCGCACGAAGCGACAACAGCGACGGCGGCGGCGGCGTCGCGCAAACGCAAGCTGCGCCAGCTGCACCATCACCATCAGGACATGCTGAGCGATGAGGATGAGGAGGAGGACGAGACATCCTTGACGGGGCCACGCCCACACGGTCGGCAAAAGCAGCGACGCAACGCCTCTGCCACGGCCTCGGCCTCGGCCAGCATCGTGGTCGATTACAGCGGCAGCGACGCCAGTTCGCTGCGCAAAAAGTTCCGTTTGAATCGGTCGGCGGCAGCGGCGGTAGCGGTGGCGGCGGCGGCTGCTGCCTCCAGTCTCTCGGAGTCGGGATTTGTGGACACCACCGCCCACAGCGGCTACCTGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGATCCGGGGGATCATCGCCGCAAGGCGGCCTGTGCCTGTCCAGCGGCGAGTCCGGCATCGGGGCGGGGGACGAGCACATGAAGTACGTCTGCCCCATCTGCGAGGTGGTCAGTGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTACGCCAACGGGGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCGTCGTCCCTGGACAGGCACGTGCTGGTGCACACGGGGGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGGCCAACCAGTCCCACCTTAATCCCGCCCAGCAGCAATCGATGACGGGCCGGGCGGAGAGCTACGAGAGCGACGCCAGCTGCTCCACAGACGCCTCCAGTGGCCATAGCCGGAGTCGCAGCAGCAGCTCCCTCACCCACAACAACAATAACAACAACAACAATTCCCAGAAAGCCAACCACAACCTGGAGATGGAGATGGAACTGGAGGAGGAGGTGAAGCATCACCTGAACCGTCGCGCCTTCAAGAAGACCATCAACAACAATGTCATCGAGAGCGAGCAGGTGGAGGAGGACGAGGAGGAGCACGGGGACGAGGATGTGGACGAGGAGGCGGACGTGGCCATGCTGACGTCTACACCGGATGTGGCCACATTGCTGGCGGGAGCCAGTGCCTCGGGAGCAGCCTCCCGCTCCGTCTCCCCCTCGTCGGCCGTCTCTGCGCCGATCCTGCTCAGCTGTCCCGCCTGCGGCGCCTCCGACTTCGAGACGCTGCCCTCGCTGTGCGACCATTTGGACGCCAGCCACTCGGATATTCCGGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGTCGCGGGGTCGGAGGACGCGCGGTGGGTGGTCTGCCGCCGCTCCTGGGCGCCAGCAGCTCGCCGCTCCACGGCGACGACGATGCCGAGGACGAGGACGAGGGCGAGGATGAGGAGGATGCGGAACGCAGGCGCCTGGAGAAGCAGCGACTGGCCGACCAGCGGGAGGACTTCTTCCAGCAGCTCTACCTCAAGGGCAAGACCGCCGGGGAGCATCCGCCGTCACCGATCAAACACGAGGCGGCGGACAGCAAGGATCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCAGCAGCTTCCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCATGGATGGCCGCGACCAGGAGGAGGAGGCCCAGGATGCCTTCACCTCGGAGTTCCGCCGGATGAAGTTGCGCGGCGAGTTCCCCTGCAAGCTCTGCACCGCCATATTCCCGAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATTTGGGTGCAGTGGGTCCGGCCGGACCCTTCCGCTGCAACATGTGCCCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGAGGATGTCAAGCGCGCCATCATCTACCATCCGGCGGAGGATGCCGGCTGCGGCGAGGATGGGAAGTCCCGTCTGGGCGAGGATCTGGACTTGAGCTTCCGATCCATTAGTCCGACACCTCCGCAGCTGCCGCTGCCGCCGCCGGCGCCGCTGCCGCACCAGGAGAGCAGCTCCCAGCTGAAGCACATGCTCCTGGGCGAGAATCAGTCGCCGGGTGGCGGAGTCGGAGTCGGAGTCGGAGGAGCAGCCGCCCCCAACCAGCAGCAGCAGCCGCCGTTGAAGATCCAGGTGAAGAGCCTGGACCAGTTGGTGGACAAGAAGCCCAGCCAGGAGAAGAGCTCTGCGCCCATCGCCGCCCTCGACTTCAGCATGGATGTGCTGGACCTGAGCAAGAAGCCATCGACCGGATCGGCGGCCATCACCCCCAGCCCCAACCCGACCCCTGCCCCGGCTCCGCCGGCGCCGCCTCAGGGAGTGCCCGGTGCCCCGGACCTGGCCGCCGCTCTGGAACAGCACCAACTGCTCCTGGCCCAGCAGCAGCTCTTCGCTGGAGCCGCCGGCGATGCCGCCTCCCAGTACGTCCAGCAGCTGTTCCGCAGCCTCATGTTCCAGTCGCAGAGCCCCGGCTTTCCCTACTTCTCCTTCATGGCGCCGCCACCGCCCCAGGCTAACCCGGAGAAGCCTCCGCCGTTGGTGAGTCCGCCCAACCGCGGCCTGACTCCCCTGCCCATGGGCGGAGTGGGTGTACCCGTGCCGCCCGGTGGCCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCCGAAACAGAAGCAGCGTCGCTACCGCACCGAGCGCCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACCCTCCGCTCCAACATGGAGCGCCACGTTAAGCAGCAGCATCCCCAGTTCTATGCCCAGCGCCAGCGCAGTGGCCACCACGTGATGCGCGGACGCGGCGCCTCCAATGCCGCTGCCGCCGCCGCCGCCGCTGCTGCTGCTGCCGCCGGCATGGCAGGAGCTGGCTCCGGTGCTGGCTCCGGATCTCATCACCATCCCGGCCATGGCCACGGCCATGGACACGCACCCATCTCCGAGCAGGTCAAGTACGCCATCCTGGCCCAGCAACTGAAGGCGCACAAGAACACGGATCTGCTGCAGCAGGCCCTGGCCCATGGATCGAGCAGCGTGGCCGGCAATCCCCTCCTGCACTTTGGCTATCCCCTGGCCACGCCCCCGCCCAACTCTGGGCTGCACAACGGCGCCGGGGGTCAGGCGGGAAACGGGCTGCCCATGGTCGGCATGGACGATGACGAGCCCAAGCTGATCATCGACGAGGACGACAACGAAGTGGAGGAGCTGGACAAGATCGAGGAGCTGGAGCTGGAGCTGCCGAAGCCTTTGGAGGCGGCCCAAAAGACCGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCGGTGACGGGCACGCCACCGCCGCCCCCGAAGGAGCAGCATCGGGAGGAGCAGCAGCAGATTGCCCCGCCGGCACCCAGCACCCTGAAGACGATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCTCTGAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGACCATGAGCTTCAACAGCTATTTCCGGCCGAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGTAGCGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTGACCAGCAGCTCCTCCGGCAGCGAACCGAAAAAGAAGTCCGCCTACAGCCTGGCACCCAACCGGGTGTCCTGCCCCTACTGCCAGCGGATGTTCCCGTGGAGCAGCTCCTTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTGGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCGGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCCAGGAGGCGGAGCGCGAGCGGGAGCGGGAGCTGGAGCGCGCCCGAGAGCGGGAGATGGAGCGGGAGCGGGAGCGCGAACTGGAGCTGGAGCGAGAGCGGGAGCTGGCCGAGAAGGAGAAGGAGCGCGAGCGCCAGCAGCTCATCCAAAAGCTGGCTGCCCAGATGGCCGCCGCCGCCGCTGCGGCTGCCTCTGCTCCCGGAGCCGGAGCCGGAGGTGTCGCCCCCGTATCCGGCATACTGGACGCCCAGGCTGGCGGGGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCCGACCGGCTGCAGTGTCTCGAGCACATCAAGCAGGCCCACGCCCACGAGTTCGCCCTGCTCCTGGCCAAGGGCGCCATCGAGAACGAGTCCGTGCTGGGCGAGTCCCAGCCACCACCAGCCAGCCAGCAGTCGCACTCCGACGACGAGGCCACCAACGGTGTGGCCGGCGGGGCAGGAGGACGCGGCAAGTATCCGGATTACAGCAACCGGAAGGTGATCTGCGCCTTTTGCGTGCGCCGCTTCTGGTCTACGGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGGCCCTTCCAGTGCGACATCTGCCTGAGGAAGTTCACCCTGAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGCGGACGCGCCCACAACGGTGATGGGCCCGGGTCCGATTGCTCCGACGACGAGCAGATTAGCTCCTCCCCGCCCGGCACCCCAGCCCCGCCGATGGCCAGCCCAGCCTCCACTGCCACCGCCACCGCCACCGCCACCGCCAGCGCCAACAACAACAATAGCTGCCACACCAACAACAACAATGTGAGCGCCGCCAAGCTGGGCCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGACGGAGTGGCGGGCCAGCCGGCTGGTGGGGGAGCACAAGGAGAACCTGGGCGAGGCCACCACCCCCTCGGGCTCCGGCACGGATCTGATCGGCAATCTGTTGGGCATCAGCGACCAGGGAATCCTCAACAAGCTGCTCTCCTCCGCCGACGAGGCAGCCAAGCTCCTGGGCGTGGATAACAAATAA
Protein Sequence
MLAAQQQHNPTTSTPNTNSTEKEMERQRRDSTTSESSLEHLDLGRTPKKLSAGSGSGGSLLQPTSTPHEATTATAAAASRKRKLRQLHHHHQDMLSDEDEEEDETSLTGPRPHGRQKQRRNASATASASASIVVDYSGSDASSLRKKFRLNRSAAAAVAVAAAAAASSLSESGFVDTTAHSGYLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSGGSSPQGGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQANQSHLNPAQQQSMTGRAESYESDASCSTDASSGHSRSRSSSSLTHNNNNNNNNSQKANHNLEMEMELEEEVKHHLNRRAFKKTINNNVIESEQVEEDEEEHGDEDVDEEADVAMLTSTPDVATLLAGASASGAASRSVSPSSAVSAPILLSCPACGASDFETLPSLCDHLDASHSDIPAKCRDCEVIFASHRQLQAHCCRGVGGRAVGGLPPLLGASSSPLHGDDDAEDEDEGEDEEDAERRRLEKQRLADQREDFFQQLYLKGKTAGEHPPSPIKHEAADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSMDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAIFPNLRALKGHNRVHLGAVGPAGPFRCNMCPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEDVKRAIIYHPAEDAGCGEDGKSRLGEDLDLSFRSISPTPPQLPLPPPAPLPHQESSSQLKHMLLGENQSPGGGVGVGVGGAAAPNQQQQPPLKIQVKSLDQLVDKKPSQEKSSAPIAALDFSMDVLDLSKKPSTGSAAITPSPNPTPAPAPPAPPQGVPGAPDLAAALEQHQLLLAQQQLFAGAAGDAASQYVQQLFRSLMFQSQSPGFPYFSFMAPPPPQANPEKPPPLVSPPNRGLTPLPMGGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAGMAGAGSGAGSGSHHHPGHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLATPPPNSGLHNGAGGQAGNGLPMVGMDDDEPKLIIDEDDNEVEELDKIEELELELPKPLEAAQKTAETILEQAIKAGKPVTGTPPPPPKEQHREEQQQIAPPAPSTLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQTMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERAREREMERERERELELERERELAEKEKERERQQLIQKLAAQMAAAAAAAASAPGAGAGGVAPVSGILDAQAGGDLPYKCHLCEGSFADRLQCLEHIKQAHAHEFALLLAKGAIENESVLGESQPPPASQQSHSDDEATNGVAGGAGGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDGPGSDCSDDEQISSSPPGTPAPPMASPASTATATATATASANNNNSCHTNNNNVSAAKLGLKLPKLHELLDKATEWRASRLVGEHKENLGEATTPSGSGTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504177;
90% Identity
-
80% Identity
-