Basic Information

Insect: Drosophila varians
Gene Symbol: prg
Assembly: GCA_018150405.1
Location: JAECWK010000125.1:1292792-1294563[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.072 6.8 7.1 0.7 1 23 212 235 212 235 0.90

2 9 0.00071 0.067 13.5 0.1 1 23 241 264 241 264 0.98

3 9 2.3e-06 0.00022 21.3 1.6 1 23 270 292 270 292 0.98

4 9 6.6e-09 6.2e-07 29.3 1.2 1 23 298 320 298 320 0.99

5 9 6.2e-05 0.0059 16.8 0.7 1 23 326 348 326 348 0.98

6 9 4.7e-06 0.00044 20.3 0.7 1 23 354 376 354 376 0.98

7 9 2.9e-05 0.0028 17.8 1.5 1 23 424 446 424 446 0.96

8 9 1.7e-05 0.0016 18.5 0.3 1 23 451 474 451 474 0.91

9 9 0.042 4 7.9 1.8 1 23 478 500 478 500 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.072	6.8	7.1	0.7	1	23	212	235	212	235	0.90
2	9	0.00071	0.067	13.5	0.1	1	23	241	264	241	264	0.98
3	9	2.3e-06	0.00022	21.3	1.6	1	23	270	292	270	292	0.98
4	9	6.6e-09	6.2e-07	29.3	1.2	1	23	298	320	298	320	0.99
5	9	6.2e-05	0.0059	16.8	0.7	1	23	326	348	326	348	0.98
6	9	4.7e-06	0.00044	20.3	0.7	1	23	354	376	354	376	0.98
7	9	2.9e-05	0.0028	17.8	1.5	1	23	424	446	424	446	0.96
8	9	1.7e-05	0.0016	18.5	0.3	1	23	451	474	451	474	0.91
9	9	0.042	4	7.9	1.8	1	23	478	500	478	500	0.98

Sequence Information

Coding Sequence: ATGTTTATCTCCGAGCCTGAAGTCTACTTGCGATCGACTGCGATCACGTGCCGTCTCTGTCACCGTGAAGCAAGCGTTGATTCGCCAAACATGTTTGACAACTCCGCGGAGTTCTGCAAGGATTCGAGCATTGCCGACGTTTGCCAGAGCCTTTGGGATGTCCAGTATGAACGCCACGAGTTTTTGTCTGAGCTCATTTGCCTCAATTGTGTTGAAATATTGGAGGACGCCTACGAGCAACGTCGGGGTATGCAGGAGCGAGAGCAAGTACTAAGGCAGCAACTAAAGATTCAGCTTAGAGAAGACGCTAAATATCGTCCAGGCTTGAATGGGAATCCTGGGGAATTCGACTCGGAAGAGGGATGTGTTATAGTTGACGTTGATCCTGAAAAGCTAGCAGAGACTAGCGAGGATGAGTTTCTGCTTGGATCCGACGGCGATTATGATGAGGACGATGAAGAGGAGGAGGAGGAGGACTTTGATGAGGATGATGATGATGACGGCCAACAAGGCGACGATGTGGACATGCCCTTGGGTATGGATGCAGCTCAAATGGCTCTGTTAGAGGCTAATATGAAGACAGCCAGATCCCATACCGATGCCAACTCTGCAGCGCCACGTCCTAAGAGAGCTTTCCTTTGCCAGTACTGCGATCTGGGTTTTACTTTGCCGTCAGAGTGCCAACAACATGAACTTAGCGCCCACGATCCAAACGCTCCATATTCGTGCGCCTACTGTAATCTGCGTCTGATCACGCGACCCGCTCTGATCTCACACATCAAGACCCTCCACGATCCGGATCGTCCTTACGTGTGTGCCCATTGCCGTAAAGGATTCGTCCGGCGTTCAGACCTAAAGAAACACACGATTGTACACACCGGCGTACGTCCTTACACCTGCCCCGTGTGCTCTAAGAGCTTTTCTCGTAATACGAACTTGACAAAGCACGTACGCATTCACAGCGGGGTGAAGCCTTTCGTCTGCCAACAATGTCCGCGTTCCTTCCAGACGGCAGTTGAAATGACGAAGCACTCACGCTCTCACTCCGAAGTAAAGCCTTTCCAATGTGGCCGTTGTCCGAACTCGTTCTCTCGAAAGGATAAGTTGATGGCTCACCAACAGATCCACACACGGCGGGATGTGGAACAACAACAGCAGCAACTGGGAGGGCTGCCGGCGATGGAGGGCGATTTGTCTCAGTACCAAGTGCAGCAGCAGCAAGTCCAAGTGAAGCCAAAGCCTCCGTCGCAGCCTAAATCTTCTCGAAATTTCCACTGCGATGTCTGCGATCGGGTGTTCCAGCGAGAGCGGGACTTGCAGCGTCACAGGGCCCTCCATATGGATTCGCTCTTTGCTTGCAAGATTTGCAATATGGGATTCAACCGACGCGAGCAGCTGCAGCGTCACGAATTGGAAGCCCATGGGCCCAGCTACACATGTGGTATTTGCTGCATAAGTTTCCTACACCAGGTGGAGTTGGAGAATCACTTGAAGGTACATCAGCTACAGCACAAAATGGCCCAGAGTGCACAAGAAGCCATTAATGCCGCCGCAATCATGCCGCTCAAAGTAATGGATCAAGCCCCAGTGCCAATGATGGCCCCTATAGTGCAGGAGCCAGTGCCAATGCGTCCCTCGGCAGCCGAACTCTCATTCTATAGCAACATGATACCGACTATGAACTTGGGATTCTACAGCGAAACGCGTCCCGATGAGTAA
Protein Sequence: MFISEPEVYLRSTAITCRLCHREASVDSPNMFDNSAEFCKDSSIADVCQSLWDVQYERHEFLSELICLNCVEILEDAYEQRRGMQEREQVLRQQLKIQLREDAKYRPGLNGNPGEFDSEEGCVIVDVDPEKLAETSEDEFLLGSDGDYDEDDEEEEEEDFDEDDDDDGQQGDDVDMPLGMDAAQMALLEANMKTARSHTDANSAAPRPKRAFLCQYCDLGFTLPSECQQHELSAHDPNAPYSCAYCNLRLITRPALISHIKTLHDPDRPYVCAHCRKGFVRRSDLKKHTIVHTGVRPYTCPVCSKSFSRNTNLTKHVRIHSGVKPFVCQQCPRSFQTAVEMTKHSRSHSEVKPFQCGRCPNSFSRKDKLMAHQQIHTRRDVEQQQQQLGGLPAMEGDLSQYQVQQQQVQVKPKPPSQPKSSRNFHCDVCDRVFQRERDLQRHRALHMDSLFACKICNMGFNRREQLQRHELEAHGPSYTCGICCISFLHQVELENHLKVHQLQHKMAQSAQEAINAAAIMPLKVMDQAPVPMMAPIVQEPVPMRPSAAELSFYSNMIPTMNLGFYSETRPDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550398;
90% Identity: -
80% Identity: -