Basic Information

Insect: Drosophila vallismaia
Gene Symbol: ush
Assembly: GCA_035047325.1
Location: JAWNPU010000090.1:5782671-5788350[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0064 0.55 11.0 0.0 1 20 249 268 249 270 0.90

2 9 0.00031 0.027 15.1 0.7 1 23 325 347 325 347 0.98

3 9 0.049 4.2 8.2 1.0 2 21 391 410 391 411 0.92

4 9 0.047 4.1 8.2 2.9 2 21 820 839 819 840 0.93

5 9 0.0088 0.76 10.5 0.0 3 21 893 911 891 912 0.91

6 9 0.0063 0.55 11.0 0.0 2 23 980 1001 979 1001 0.98

7 9 0.0037 0.32 11.7 1.3 1 23 1007 1029 1007 1029 0.99

8 9 0.0013 0.12 13.1 0.9 1 23 1078 1101 1078 1101 0.96

9 9 0.26 22 5.9 0.3 2 20 1218 1236 1217 1238 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0064	0.55	11.0	0.0	1	20	249	268	249	270	0.90
2	9	0.00031	0.027	15.1	0.7	1	23	325	347	325	347	0.98
3	9	0.049	4.2	8.2	1.0	2	21	391	410	391	411	0.92
4	9	0.047	4.1	8.2	2.9	2	21	820	839	819	840	0.93
5	9	0.0088	0.76	10.5	0.0	3	21	893	911	891	912	0.91
6	9	0.0063	0.55	11.0	0.0	2	23	980	1001	979	1001	0.98
7	9	0.0037	0.32	11.7	1.3	1	23	1007	1029	1007	1029	0.99
8	9	0.0013	0.12	13.1	0.9	1	23	1078	1101	1078	1101	0.96
9	9	0.26	22	5.9	0.3	2	20	1218	1236	1217	1238	0.91

Sequence Information

Coding Sequence: ATGAGGAGAGGGTGTTGTGATGGCACTCGCTTGAGACAATCGCTGGAGAAGATCTGCTGCACCAGCACCATCGCCATCACCATTGGGGCTAATCCTCGGCGGTGGTGCAGAGGCAGCTGTCGCTGGGGGCTTCGAGCTGGGAGACTGCAGATCGGAGCTGAAGGCAAAGCCATTGTTAGCTATTCCAAAGATTTAACCGCACAGGAGCTAGGCGAAGAGAAGCAGCTCCATCAGCTGGAAGATCAGCTATCAGATCAGATGGACGACTCCACTGACAACCACGAAAatagcaacaataacaataatgaGGCGGAGGAGGACACGGTGTCCGACCAGCCGGAAGAGACTAATGCCGAGGATTTGATGGAAACTGAGATGATGGATCAGGATCATGAGCCCCAGCCggccgaggaggaggacggACTTGACCTGCCTCGCAATAGTCCCAGCACACCACCAAGAAGCGCCACCGGATCTCCACGGTTGATTCCAAAGCTGGAGCAGCCTTGTACACCACCCTCAGAGCCAGAGGCCGAGGCGGAACCATCGCCGTGTCCCTCCCCATCTCCCATTGCTCCCAAATTGCCCAAACTGCGGTTGAACGCCCTCCTGGCCTCAGATCCTGCCCTCAAGCCGGATGCCAAGGAGCTGAATCTGTCGGAGCCACGTCTGCTGGCTCCTCCGCCGCTGATCAAACCGGAAGTACAGCCGGAGATCGTGGAGCCACTCCTGAAACCGGCCCGGTTCATGTGTCTGCCCTGCGGTATTGCCTTCAGCTCACCCTCGACGCTGGAGGCCCATCAGGCCTACTACTGTTCGCACCGGAATAAGGACACGGAGGAGGACCAAGGAGCGGGCACTGGTGACAAATCGGCAGGCGGCGTTGGCGGAGCATCCTCGGGAGCGGCTGGATCCGGCTCGGGAAGCGGTTCCTCGGAACCACCGGCCAAAATGGCCAGGACTGGCAAGCAGTACGCCTGCTCCCAGTGCTCCTACAGCGCCGACAAGAAGGTGTCCCTCAACCGACACATGCGAATGCATCAGACATCGCCGGCTACTCCCAGCCTGGTGGTGGCCAGTTTGCCGAATCTCGTCCAGAACGGCTTGCCATCGACCGGAGTGCCGACGAATTCCCTCGAGGAGAGCCCTAGTCAACAGCAAACGGATCGCTATTGCAGCGACTGTGATATCCggtttaataatataaaaacctACCGGGCTCACAAGCAGCACTACTGCAGTTCCCGCCGGACAGAAGGTCAGCTAACACCCAAGCCGGATGCATCGCCCGGCGCCGGCGGAGGATCGAGTGCATCGGGATCCGTTGCCTCGGCCGTGGGAGTGCCTGGCCAGGGAACAGCTCCCGGCAAACTGAGTCCCCAGACCCGGAACAAGACACCCACGCCGGCCATGGTGgctgcagcggcggcggcggcagcggcagcagctgcGGCAGCTGCCTCGTTGCAAGCCCCACCACCCCAACCGTTTCTGGCTCTGCCCACACACCCCATCATCATTGTGCCCTGCTCCCTGATTCGGGCAGCCAGCATCATTCCAGGGCCATTgCCCACACCCTCGTCGGGAATCGTGAATCCGGAATCCACCTGCTTTACAGTGGAGAATGGTACCATCAAGCCCTTGGCCACCGCCTTGCTGGGAAGTGCTCTGGCCGGTACCAGCAGCCAGCTGAACAATTCCACCGTCAACCTGCACAACCTGCCCATTCCCAACCTGGAGCCAGAGCGTCCTTCTGCCCCCTCATCCGCTGCAGAAGCCATAGAGCCCAAGAGCAGTCCACCGGAGCCGAAACGCAAGGAAGCAGGAAGCACTCGAGAATCTGCCCCTTTGGATCTTTCGTTGCGTCGCTCCCCAATCTCCCTTAACTCCTTGAGCCTGCGGCAGCGGCAGTTGCAGCACCTACTGGACATGGAGGAAGTGCTTGGCCTGGGTACCGTGGGAGGAGGCATTACTGGCAAGGAGAATATAAACACAGCTGCTACCGGtggcggaggaggtggaggaaatggaggaggaggaggcggaaaTGTCACTCCCGAGCAAATCGTGTGTGCCCCTTCCCTGCCGAGCAGTCCCTCGATGAGTCCTTCACCCAAAAGGCGAGCCATCAGCCCGAGGAGCTCAGGGCCAGGAAGTGCGGCCTCCATGTCGCCGCCCGGCCTGAATGTGGCTGTTCCTCATCGTCTAGAGATGCTCTCGGCCATGTTGCCGGCCGACTTTGGTCTCTCCGAGTCGctgttggccaaaaccaaTCCGGAATTGGCCCTGAAACTAGCAGCAgctgcggcggcggctgcaGTGGCCGGTGGGGCAAGTGGCGCTACACCCGCCTTTCCTCCCGTGCCGCCTGCTCAAACGGGAGGCAACAACTCCTCGGGTGGTGGATCAGTCGGTGGCGGCCAGCAGCCACAGATCTATGTAAAACAGGGCGTATCGAAGTGTAAGGAGTGCAATATCGTTTTCTGCAAATACGAGAATTATCTGGCGCACAAGCAGCACTACTGCTCGGCCAGGAACCAAGAGGGATCGGGCGATAGCGATTCCAAGTCGGCCGTTTCGCCCTCTAATCCCGGCGGAGCTGGTGGCTCTGGAGGCGGTGGAGCAGGGGCAGCAGCTGCGGTTGAAACATCGCCGGTGGCCTATCAACAGCTTATCTGCGCCGCTTGTGGCATTAAGTACACTTCTTTGGATAACTTGCGGGCCCACCAGAACTACTATTGCCCCAAGGGTGGGGCAGCTGCTGCCGCTCCAGCTGGGACACCCGCAGATCCTGGACAGTTGGCTATCGTGAAGGAGAAGTGCGGCAAGTGCAAAACCCTTCACGAGATAGGACTTCCCTGCCCAGCTCCCGCCTCCAGTCCACTGACAGCTCCCACCAATTCCAACTCCCAATCGAGCGCCTCGAATAGCGTCAACAAGTGCCCCGTTTGCGGTGTGGTCAGTCCCACGGCGGCTCTGGCCAGGAAGCACATGGAGATGCATGGAACGGTCAAGGCCTTTCGTTGCAGCATCTGCCAATACAAGGGCAACACGCTCCGTGGCATGCGCACTCACATCCGGACGCATTTCGACAAGAAGACTAGCGATGTGAACGAAGAGCACTACATGACCTGCATCTTCGAGGAGGAGAGTGCCAATGTGGCCCAGGAGCTGCCATCATCGGGAGCTGCCGTGGCACCATTAGAGACCATGGAGCATCCGCCACAGCTGTTCAATTGCGATTACTGCAACTATGGTTCCACCTACAAGGGCAATGTGCTGCGTCATATGAAACTTTTGCATCCCCATGTGGCCATCACTTCCCCTTCGATTTCACCCGAGTCCCGGGAACAGGAGGTCATTGCCAactccacacctaatcaacactCGAATGATGGCTCCAACGGCGAAGCCACAAGCTTCCACATCAAATCAGAGCCCTTGGATGCACCTGCCACACTGAGTCTGGTGCATGAAAACAACAACTCACCGATACCCACGCCACACATCAAAGCCGAACCCCTGGACATTGGCATTGACGTGGCACTGGCACCCCCGCCGGTGGCTTCTCCGCTGGGCAACAGCAGTGTGGCAGCTGctactgcagcagcagccgctgcagctgccgccgctgccgaGGCAATGAAGAAATACTGCTCCGTCTGCGACATATCCTTCAACTATGTGAAAACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGCCCATTCGCCCGGAGGCCAACGACAGTCCCAGTCCGAATCATCTAGCGGCCGGAGGAGGAGTGGGTCTGGGATTGGGGGTGGGGATGGTGGGTGGCGGCCAACAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MRRGCCDGTRLRQSLEKICCTSTIAITIGANPRRWCRGSCRWGLRAGRLQIGAEGKAIVSYSKDLTAQELGEEKQLHQLEDQLSDQMDDSTDNHENSNNNNNEAEEDTVSDQPEETNAEDLMETEMMDQDHEPQPAEEEDGLDLPRNSPSTPPRSATGSPRLIPKLEQPCTPPSEPEAEAEPSPCPSPSPIAPKLPKLRLNALLASDPALKPDAKELNLSEPRLLAPPPLIKPEVQPEIVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDTEEDQGAGTGDKSAGGVGGASSGAAGSGSGSGSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPATPSLVVASLPNLVQNGLPSTGVPTNSLEESPSQQQTDRYCSDCDIRFNNIKTYRAHKQHYCSSRRTEGQLTPKPDASPGAGGGSSASGSVASAVGVPGQGTAPGKLSPQTRNKTPTPAMVAAAAAAAAAAAAAAASLQAPPPQPFLALPTHPIIIVPCSLIRAASIIPGPLPTPSSGIVNPESTCFTVENGTIKPLATALLGSALAGTSSQLNNSTVNLHNLPIPNLEPERPSAPSSAAEAIEPKSSPPEPKRKEAGSTRESAPLDLSLRRSPISLNSLSLRQRQLQHLLDMEEVLGLGTVGGGITGKENINTAATGGGGGGGNGGGGGGNVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGPGSAASMSPPGLNVAVPHRLEMLSAMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGGASGATPAFPPVPPAQTGGNNSSGGGSVGGGQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSGDSDSKSAVSPSNPGGAGGSGGGGAGAAAAVETSPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAAAAPAGTPADPGQLAIVKEKCGKCKTLHEIGLPCPAPASSPLTAPTNSNSQSSASNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEESANVAQELPSSGAAVAPLETMEHPPQLFNCDYCNYGSTYKGNVLRHMKLLHPHVAITSPSISPESREQEVIANSTPNQHSNDGSNGEATSFHIKSEPLDAPATLSLVHENNNSPIPTPHIKAEPLDIGIDVALAPPPVASPLGNSSVAAATAAAAAAAAAAAEAMKKYCSVCDISFNYVKTYLAHKQFYCKSKPIRPEANDSPSPNHLAAGGGVGLGLGVGMVGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00488262;
90% Identity: iTF_00550504;
80% Identity: -