Basic Information

Insect: Drosophila vallismaia
Gene Symbol: Znf574
Assembly: GCA_035047325.1
Location: JAWNPU010000066.1:13025146-13027377[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 9.8 8.5e+02 0.9 0.1 3 16 55 68 54 70 0.85

2 11 2.4 2.1e+02 2.8 2.6 2 23 348 370 347 370 0.94

3 11 0.053 4.6 8.1 0.1 6 23 380 397 380 397 0.98

4 11 5e-06 0.00043 20.7 3.1 1 23 403 425 403 425 0.98

5 11 0.25 22 5.9 0.8 1 14 434 447 434 457 0.73

6 11 0.00048 0.042 14.5 2.6 1 23 465 488 465 488 0.97

7 11 0.14 12 6.7 0.4 3 23 496 517 494 517 0.92

8 11 0.45 39 5.1 0.2 2 23 529 551 528 551 0.93

9 11 0.0014 0.12 13.0 4.1 1 23 558 581 558 581 0.93

10 11 1.7e-06 0.00014 22.2 1.4 1 23 587 609 587 609 0.98

11 11 0.036 3.2 8.6 3.3 1 23 615 638 615 638 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	9.8	8.5e+02	0.9	0.1	3	16	55	68	54	70	0.85
2	11	2.4	2.1e+02	2.8	2.6	2	23	348	370	347	370	0.94
3	11	0.053	4.6	8.1	0.1	6	23	380	397	380	397	0.98
4	11	5e-06	0.00043	20.7	3.1	1	23	403	425	403	425	0.98
5	11	0.25	22	5.9	0.8	1	14	434	447	434	457	0.73
6	11	0.00048	0.042	14.5	2.6	1	23	465	488	465	488	0.97
7	11	0.14	12	6.7	0.4	3	23	496	517	494	517	0.92
8	11	0.45	39	5.1	0.2	2	23	529	551	528	551	0.93
9	11	0.0014	0.12	13.0	4.1	1	23	558	581	558	581	0.93
10	11	1.7e-06	0.00014	22.2	1.4	1	23	587	609	587	609	0.98
11	11	0.036	3.2	8.6	3.3	1	23	615	638	615	638	0.97

Sequence Information

Coding Sequence: ATGGATACCTCTGTTTGCTGTTTACTCTGCATGTGCGAGTATCAGGCGATGATGGGCGACTACATAGATGTGCATTCGAACAGGGGATCGCAACTGGAAGTTGCCCGAATTGTTTCCCAGCACTTTCCGTTGCAGATATGCCAGGAAAGTCAGGACAGGATCTGCGGACGCTGCTGGAAAACAGTCTCCGACTTTCATTCACTCCACGAATTCGTCAGCGCTGCTCAAAACTCATTACAGGAAACCAAGGTGTTGTTTATGGAAGATGATCCTCTTACCCAGGCTGCCCCCGCCTACACGGACGTTCCTAAATTGGCAATTGAACAGGTAGAACAGGTGCCGGCGCCATCAGAAGTAGCTGGGCGTAACTTCTTCTATCCGGAAATCAAAATAGAGGCGCACGAGCTGGACCATTTACCTAGAATAGAGATCCTTGAGAGCACGAGCACGACCACCTCGCAGGCTAACCAAGATCAATCTGATGGAACAACCAGACGTCTTAGGAAACGCGTGAAAGCCGAAGAAGGATCACTTGCACTGATCAATGAGCAAGGAAAAGATGAGCCTTTAGAAACGATGGAGTTGGAGCCAGCTCCACCAAAAAAACGGCGAGGGCGTCCCCGAAAGGCAGACAGCGCCAGTGGTACACTCTCGGCCACAGTCATTGCATCGGCAATTACAGATAAACCGAAAGAAGATGCTGAAGTAGCTCTGAAATCAGAAGAGATCGAGGAATTTATGGATGACGACCCAGAATTCACTTACAATTTTGAAGATGGCCTGGTGCCAAGTGATAATTCTTCTGACGATAACTTTGAAAGTAacgattttgatacagattcgGACTTTGAGGTGGACGGCCACGACAAGCAGGAGTTCGCGGTGCTGCCCAAGCGAACTGTGGTGCGACCCAAGAAGTACAAGAAGCGCACGAAACCGGCGGCGCCAAAGGTGCGCATGCCCCGTGAGATGCTGGAGCAGCGCAAAAAGCATCAAGAGGAATACGACAGCATTATAGCAAAGTTCTTTACCGACGTACTCCCATGTTCCATTTGCAACTTGCTGGTGCATAACTTCACTGAGATGCAACGCCATCACCGACTGACCCATCAGGTGGATCCTGGATACATGATGTGCTGCGGCCGAAAGTTTACACAGCGTAAAGTTCTGGCGGAGCATGTGCTGGTCCACTGGAATCCGGATCACTTCAAGTGTTCCGTATGCGAAAAGTCTTTCCAGAACTCGCGACACCTCGAGTCGCACCAGCAAGTGCATATGGATCCGGCCATTAAATTGACCTTTAGCTGCGACATTTGCACAAAAACCTTCCTCAGTAAAACGGCCATCGACTACCACAAGCTTAACAAGCATGTGCCCAAGTCGGAATTCAAATTTACCTGTTCCGAGTGCAATAAAAAATTCCTCACTGAGCGGAAGCTGAAAAACCACATGAGCTCGATGCACGACCCGGAAAGTACTATCATCTGCGACAAGTGCGGGAAGCAGATGCGAACCAAGATCATTCTGAAAAAGCACCAGGAACTGATGCACTCCGACAAGCCACGTCCGGAACCAGAGCTCAAGCAGTGTCAAATCTGCGGCGCTTGGCTGAAGGGAATGACTGGCCTCAAGCAACACATGAAGAGCATTCACGTGGAAAGCGCAGGCGAGCATCGCTGTCACATTTGCAGTAAGGTCTCGCCGAATGCTCGGGCCTTGAGGCGCCACATATACCATAACCATGAGTGCGAGCGCAAGTTTAAGTGCACCATGTGCGAAAAGGCCTTTAAGCGGCCGCAGGAACTGAAGGAACACACGTCCACACACACTGGCGAGGTGCTGTACACCTGCCCCAATTGCCCGATGACCTTCTTCTGCAGCGCCAATATGTACAAACATCGCCAGCGGTTGCATCGCGCACAATACGAAGCGGATAAGAACCAGCCAAAGCCGCCAAACATTTTGAAGATCTCGCGCATCGCTTCATCCCAGAACAAACCCAAACAGGACATTTAG
Protein Sequence: MDTSVCCLLCMCEYQAMMGDYIDVHSNRGSQLEVARIVSQHFPLQICQESQDRICGRCWKTVSDFHSLHEFVSAAQNSLQETKVLFMEDDPLTQAAPAYTDVPKLAIEQVEQVPAPSEVAGRNFFYPEIKIEAHELDHLPRIEILESTSTTTSQANQDQSDGTTRRLRKRVKAEEGSLALINEQGKDEPLETMELEPAPPKKRRGRPRKADSASGTLSATVIASAITDKPKEDAEVALKSEEIEEFMDDDPEFTYNFEDGLVPSDNSSDDNFESNDFDTDSDFEVDGHDKQEFAVLPKRTVVRPKKYKKRTKPAAPKVRMPREMLEQRKKHQEEYDSIIAKFFTDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAIKLTFSCDICTKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICSKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRIASSQNKPKQDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494659;
90% Identity: iTF_00504239;
80% Identity: -