Basic Information

Insect: Drosophila vallismaia
Gene Symbol: PRDM5
Assembly: GCA_035047325.1
Location: JAWNPU010000025.1:7708110-7710088[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.085 7.4 7.4 0.2 3 23 268 289 267 289 0.92

2 10 4.8e-05 0.0041 17.6 0.1 6 23 298 315 298 315 0.99

3 10 5.4e-06 0.00047 20.6 0.4 1 23 321 344 321 344 0.98

4 10 9.3e-05 0.0081 16.7 0.4 1 23 353 375 353 375 0.97

5 10 0.013 1.1 10.0 5.5 1 23 382 405 382 405 0.97

6 10 6.3e-05 0.0055 17.3 1.9 1 23 411 433 411 433 0.96

7 10 0.27 24 5.8 0.9 2 23 442 463 441 463 0.96

8 10 2.1e-05 0.0018 18.8 2.4 2 23 469 491 468 491 0.95

9 10 1.1e-06 9.3e-05 22.8 0.7 2 23 498 519 497 519 0.96

10 10 0.00016 0.014 16.0 4.4 1 23 525 548 525 548 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.085	7.4	7.4	0.2	3	23	268	289	267	289	0.92
2	10	4.8e-05	0.0041	17.6	0.1	6	23	298	315	298	315	0.99
3	10	5.4e-06	0.00047	20.6	0.4	1	23	321	344	321	344	0.98
4	10	9.3e-05	0.0081	16.7	0.4	1	23	353	375	353	375	0.97
5	10	0.013	1.1	10.0	5.5	1	23	382	405	382	405	0.97
6	10	6.3e-05	0.0055	17.3	1.9	1	23	411	433	411	433	0.96
7	10	0.27	24	5.8	0.9	2	23	442	463	441	463	0.96
8	10	2.1e-05	0.0018	18.8	2.4	2	23	469	491	468	491	0.95
9	10	1.1e-06	9.3e-05	22.8	0.7	2	23	498	519	497	519	0.96
10	10	0.00016	0.014	16.0	4.4	1	23	525	548	525	548	0.96

Sequence Information

Coding Sequence: ATGATTTGCCGCCTCTGCCTGCGCAGCCTGAGTCCCGGCACAGCCGTTTTTCTTTTCGAAACGAACGAGACTCTGGCGGAGACGCGCCTGGTTAAGATAATCGCCAAGTTCCTGCAAATGGAAATCCTTCCCGACGATGCAATCTCGACCAGCGTGTGCACAGAGTGCTGCGAGCACCTGGAGGACTTCCACAGCTTCTGGCAGCTGGTGGAGCAGAAACAGAGCACGATCATGAATGAGGAGTTTATTTCCGTGGACGTCGATTGCGGCGACCTCAAATGGACAGGCGGCGTGGACGTGAACCTCGACGAACTGGCGCTGCCCGCGGGCGACGTCGACGAGAAGCCTCTGGACATGAACAACCTAAGTTTGTTGGGAAGCGTACTCGATGTGAATGTGGACAGTGTGGAAGTAAGCCCCTCCAAGAAGCAGTCCGAGGATGGAGAGAAACCTTTGATACAGAAAAGTGATAATAGCGATTCGGAGCCCGAGCCGACATCGTTCCCCGCCGAAGATTCATCTTCTGATGACGAACCACTGGTCCGGCTGAAGGGAAAGATAAAGTCGAAGCGCAAGGTAGGCACCCGCTCAGCTAGGCTTAAGCGATCGATTACCCTTCAGCAGGAGCTCAAGGAATTGGTTACCGGTGGCAGCCGGCGGCGCACCAAGCAGTCCACTGAGACCTCCGAGCTGCAGGAGACGGAGCTGCAGGCGGTGCTTGAGCGCAAACCCAAGGGCTGTTCCCGCGCCCAGCTGGCCAAGCGGTATGAGGAAGCCATCGCCAGTTACATGAGCGCCAATTGCGATCTGTGCGACTTTAGCGCCCCGTACCTGTCCGACCTAAAGAATCATTTCCAGGAGGTGCACCAGCGCGAATACTACATTAAATGCTGTGGCAAGGTCTTTGCCCGAGCCTCCAAGCTAATGGATCATATCCGTAAGCATGTCAACCCCAAACTCTtcacATGCACCATCTGCCAGAAATCGCTCAATTCCCAAGACTACCTGGCCACCCACATGGAGACGGTGCACAACAAGGTGGCCCAGGTTCTGAAGTTTCCCTGCGCCAAGTGTGATCGCACCTTCAGCAGCGAGCGCCGATTGGCCAATCATTTGGCCAAGCATGACTCTGACCAGTTGGAACACACCTGCGAGATCTGCTGCAAGAGCTTTGCCAATGTGCATCGTCTGCGGCGACACATTCAATCTATCCACGAGGATCTGCACCGGCACGTGTGCGATATCTGTGGAAAGAAGTTCAAGTTCAAGCCCTCCTTTGATCGTCACCTGCTGGAGCACCAGGGCGTGGTGGCGCCCGCCATGGAGTGCTCGGTATGCGGAGTATGGCTGAAGAACGAGCACAGCTTGCGCCTGCATCGATTCACCCACGATAGCACGGACACTGAGTGTCCGCACTGCGGCAAGACTTGTTCGTCGCGCACCGCTCTGCGGGGTCACATCAAGTATGCCCACAAGCTGACAACGAACCTGCAGTGCACCTACTGTGAGAAGACGTTCAAGCAGCAGCGCAATCTGGACGAGCACATGGCCATTCACACGGGCCTGCAGCTCTACAACTGCCCGCACTGCCCCAAGGAGTGTCGTTCTCGTTCCAACATGTACGTGCACATCAAACAGCGCCACGCGGATGAATGGCTGCGTGCCAAGATGGCCCGCTCTCACAATCCGCAATTCAAGCCTGGTTCAGAGGCGACTGCCGCGCAATCCTGA
Protein Sequence: MICRLCLRSLSPGTAVFLFETNETLAETRLVKIIAKFLQMEILPDDAISTSVCTECCEHLEDFHSFWQLVEQKQSTIMNEEFISVDVDCGDLKWTGGVDVNLDELALPAGDVDEKPLDMNNLSLLGSVLDVNVDSVEVSPSKKQSEDGEKPLIQKSDNSDSEPEPTSFPAEDSSSDDEPLVRLKGKIKSKRKVGTRSARLKRSITLQQELKELVTGGSRRRTKQSTETSELQETELQAVLERKPKGCSRAQLAKRYEEAIASYMSANCDLCDFSAPYLSDLKNHFQEVHQREYYIKCCGKVFARASKLMDHIRKHVNPKLFTCTICQKSLNSQDYLATHMETVHNKVAQVLKFPCAKCDRTFSSERRLANHLAKHDSDQLEHTCEICCKSFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFDRHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTECPHCGKTCSSRTALRGHIKYAHKLTTNLQCTYCEKTFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLRAKMARSHNPQFKPGSEATAAQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492388;
90% Identity: iTF_00481701;
80% Identity: -