Basic Information

Insect: Drosophila vallismaia
Gene Symbol: ZNF526
Assembly: GCA_035047325.1
Location: JAWNPU010000037.1:1552341-1554351[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.15 13 6.7 0.2 1 21 314 334 314 335 0.95

2 10 1.5e-06 0.00013 22.4 0.2 1 23 343 365 343 365 0.99

3 10 0.0003 0.026 15.1 0.3 1 23 368 391 368 391 0.93

4 10 6.3e-07 5.5e-05 23.5 0.8 2 23 398 419 397 419 0.98

5 10 3e-08 2.6e-06 27.7 1.0 1 23 425 447 425 447 0.98

6 10 4.3e-06 0.00037 20.9 0.7 1 23 453 475 453 475 0.99

7 10 0.001 0.087 13.5 3.0 3 23 483 503 481 503 0.98

8 10 0.0009 0.079 13.6 0.3 1 23 509 531 509 531 0.98

9 10 0.00024 0.021 15.4 5.8 1 23 537 559 537 560 0.96

10 10 0.0011 0.097 13.3 0.1 1 23 565 587 565 587 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.15	13	6.7	0.2	1	21	314	334	314	335	0.95
2	10	1.5e-06	0.00013	22.4	0.2	1	23	343	365	343	365	0.99
3	10	0.0003	0.026	15.1	0.3	1	23	368	391	368	391	0.93
4	10	6.3e-07	5.5e-05	23.5	0.8	2	23	398	419	397	419	0.98
5	10	3e-08	2.6e-06	27.7	1.0	1	23	425	447	425	447	0.98
6	10	4.3e-06	0.00037	20.9	0.7	1	23	453	475	453	475	0.99
7	10	0.001	0.087	13.5	3.0	3	23	483	503	481	503	0.98
8	10	0.0009	0.079	13.6	0.3	1	23	509	531	509	531	0.98
9	10	0.00024	0.021	15.4	5.8	1	23	537	559	537	560	0.96
10	10	0.0011	0.097	13.3	0.1	1	23	565	587	565	587	0.96

Sequence Information

Coding Sequence: ATGGATGTTGACAAAATTTGCCTCACATGTCTCAGCTCCTCGGGTCCTCTGGTGTCCATTTACGATGGGAGCTCTGGGGGCTGCTTGGCGGATATGCTGCGCGAATTCACAAAAACAAAGCCTCGAAAGAACGATAACCTGCCTGAGAGGGTGTGCCTGGGCTGCCTGAGCGAAATAAACCACTGCTATACGTTCAAGATTAAATGCGAAAACTCCAGCCGGACCCTGAGGCAACTGTTACCCAACGCTTTGCCGGAGGAGCCCGAACAAAAGATCTTTAATGATGCAGCAATAAACACCGTGGAACAGGGTGTGCAAACGATAGACTGGGCACCCCACCAATGCAGCGCATCCGTGCAAACGGACGCACTGTCCACCGCGGATGCCGAACAGAATACGAGTCTGGAGAAGCAGGATATACCAGAAGATCTGGAGGAGGACGAGGGAGAGGTTTTCGACTATGAACTAACTGAAGCCCCAGAGGATAAGACACAGAACATTATCCTTCACCTGCAGGACAGTTTAAAGGACGACAAAGATGTTTTGTTTACCCAAACCGATGTCATTTATGATGGCGACGACAATGAACTGGACCAGCAGATTCGAGAGTGCAACATGGCCATATTCGAGACGGCTGACGGTGAGGCGGAGATTGTGCAATTGCCCTCTCCACAGGTAACCACCAGAAAAAGCGCCAAACTAGCCAAAGAAACGCCGGAAACTAAGCCAGAAGTTCAAGAGGAGGAACAGCTCCAGACGGCCAAAAGGGCCTCACGTCGCAGAACCGCAGTAAAGCTGGAAGAGAAAACGCAGCCACCAATAGAAGCAACAGCTACTCCAGCAAAACAACTCCGTTTGGGAAGCACTCGGAAATCCCAGAACTCAGTCTCCGTCGCCACACCGGCAGCCACTGCATCAACCTTAACAGCTGAACTGAAGTACCATTGCGATAGATGCAATGCGGGCTTTGCGCTGGAAAAATCGCTGATCATTCACAAGCGCCAGAAAGGCTGCACCAATCGCAATTTCAAGTGCGACGAGTGCGAGAGGGTCTTTGTATCGCCGGAACACTTGGCCGAGCATCAGGCCACTCATGGAATACATACCTGCGCGGAGTGCGGCCTGCAGTTCGAGTCCAAAGAGCAGCTAGGCAAGCACATGGTGCAGGGTCACAAGCGAAACCTCCGTAATCAGTGCAACATCTGCCAAAAGGTCTTTACGATGCTTTCCACCTTACGTGACCACATGCGAATACATACCGGCGAGAAGCCGTTTGTGTGCAATATTTGCGGCAAGAGCTTCACCCAGAATGCCAATTTAAGGCAGCACAAACTCCGCCACTCGGAGACCAAGAGCTTTAAATGTGAGCTGTGCCCGCACACGTTCGTCACCAAGGCGGAGTTGGCCTCTCATGCCCGCACCCACACTGGCGATAAGCCTTTTGGATGCGAGGTCTGCCAGGCAAAATTCACCACCAGCTGTTCGCTGGCCAAGCACAAAAGAAAACACACGGGAGAGCGTCCTTATGCCTGCGACCTTTGCCCGATGAGGTTTACTGCCCTCAATGTGCTCAAGAATCACAGGAGGACGCACACTGGCGAGCGGCCGTACGTGTGTCCATTCTGCTCCAAGACCTTCACTCAAAGAGGCGATTGTCAGATGCACCAGCGCACCCACCACGGCGAACGCATCTACATCTGTCCGGTGTGCAACGAAGAGTTCAAGTCCATGCCGGATATGCGTTCCCATTTGTCGGCGCACGAACAGCACGACAAGCGACTGGTGCACTTCGCTCTGCTAAGCAACAAGGAGAATGGCAGTGGAAGTGGTGGCCTCGAAGAGGACCTAAACGAAATGGCAGAAACGACGTTGATGCTCtaa
Protein Sequence: MDVDKICLTCLSSSGPLVSIYDGSSGGCLADMLREFTKTKPRKNDNLPERVCLGCLSEINHCYTFKIKCENSSRTLRQLLPNALPEEPEQKIFNDAAINTVEQGVQTIDWAPHQCSASVQTDALSTADAEQNTSLEKQDIPEDLEEDEGEVFDYELTEAPEDKTQNIILHLQDSLKDDKDVLFTQTDVIYDGDDNELDQQIRECNMAIFETADGEAEIVQLPSPQVTTRKSAKLAKETPETKPEVQEEEQLQTAKRASRRRTAVKLEEKTQPPIEATATPAKQLRLGSTRKSQNSVSVATPAATASTLTAELKYHCDRCNAGFALEKSLIIHKRQKGCTNRNFKCDECERVFVSPEHLAEHQATHGIHTCAECGLQFESKEQLGKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHTFVTKAELASHARTHTGDKPFGCEVCQAKFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHHGERIYICPVCNEEFKSMPDMRSHLSAHEQHDKRLVHFALLSNKENGSGSGGLEEDLNEMAETTLML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476066;
90% Identity: iTF_00546099;
80% Identity: -