Dust010295.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ustulata
Gene Symbol
-
Assembly
GCA_035047365.1
Location
JAWNPT010000094.1:8885120-8891566[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0019 0.13 12.8 3.0 1 23 969 991 969 992 0.95
2 8 0.18 12 6.6 1.0 1 23 997 1020 997 1020 0.96
3 8 8.9e-05 0.006 17.0 0.8 1 23 1212 1235 1212 1235 0.96
4 8 0.0025 0.17 12.5 0.8 2 23 1244 1265 1243 1265 0.97
5 8 0.039 2.6 8.7 0.3 1 23 1272 1295 1272 1295 0.96
6 8 1.5e-05 0.001 19.4 1.4 1 23 1301 1323 1301 1323 0.97
7 8 8.2e-07 5.5e-05 23.4 2.2 1 23 1328 1350 1328 1350 0.99
8 8 0.0008 0.054 14.0 4.4 1 23 1356 1378 1356 1378 0.99

Sequence Information

Coding Sequence
ATGGTGGCCAAGTTCCGACGGCGTTGTGTTCGCGTGCAGCAGCGACTTCAGGAGTACGCCCAGCAGATTGCCCAACGCCAAGCACGACTCGACAAGGAAACAAATAACCAAGCAATAACCAATCTGCCTGAATCGCAACCGGAGCGCAAGCGTCGCCTGGAGGAGTCGCCAACAGTTCAGAGCGAAGCATCATCGCCCAAGCTGAAACGACGCAATGTACCCCACCTTGCAACGACAATGACGACTAGAAACTCCAAGTCGAGATCGCCATGCAAGAGAATCAACAAGCCCTGGCGAACGAAGGCGGCGCGAAAGCAACTGTCGGAAACGTGGTCCACAAGCTCCTCGTCGTGTCTGACCACAGAGCGctctgcagcaacaacagcaccagtTTCCAATTGCTCTTCGTCCACATCTTCATCGTCGGGTCAGACAACACCGGAGCACCTCAGCGACTTGTCTGTAAATCCGTGTCGTGGCTTCCCCAGCGATGGCAATTCCTCGACCTCATTGACCAACTCCGACGGTCAAACGACGTCGCCCTCGAAAGCCAAACTCCAGTTTCCGCCCAAACGCGCCCAAATAGTTATGCGGCGCAGGCGAAGATTGAGCACGCCCGTTAAGCGAGCAAAGCGCATCGTGCGGAAGACGTCGGAAATGACAAAAGATGCGCCAATAAAAGAGCTAAATATAAAACCGGAAGCGGAGCTGTCCAATGAACATACGAAACTCGCAGATGAAGCGCATTTAAACAACAACTCGGAGGAGGCACTATCGAGCAGCACAGATGAATCCTCGACCGCCAGCTGTGGCACTGAAGGGGCAGAGGAAGATGACAGCAAGATGACTGAAATAGAAAAAGATCCCAAAGCAGAAAATAACACTGAGGAGGAAACAATGCCAAATGAGCAATTGCAGAGCCCAGCCAAAGTAATAAATGAAACGACTGAAACATTGAGAGAGGAAGCAACtgaaacaacagcagctgaggAAGAGATCGAGCAAGCTGTGACTCCagtgcagtttgaggagttgACCTCGTCCACAGAGCAAATGGCTCCTGGAGTGCCGTCGCCCGAATGCGAGGTGGAGGTGAGCATGACATCAGCGAATGAGTTGATTGTGAGCATTCCACTGGAGGCGCTCGACGATGAGCTGCAGCACAAACTGTGCAATGCCGAGCCAGAGGCAGAGACTGAGCCGGAGCGTGAGGAGGGAGAGAagggagcagcagctggcaagGAGAACGGTGAGATCGACGATGTGAATAACAATGCGAATGTCGAGCATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCGAAACCAAAGAAATTGAAGCAGAACCCGATGGAGGAGGAGTTGatggtggaggaggaggaggcggcgtGGATGATGACATGGCATCACTAGAAAGTCTAGTGGAGCTACCAAAGCAAACAGTTGAGGAGCCACTGCCTACTCGCCCAGCTGCCAGCTCGATGGACTTTTTGGCCGAGTTCGAGAAGCACTGCGAGAAGACGCTGAAGCAGCAGGCGGCGCCATGCGAACTCGAACTGGAGGAGGCCAAGCAGCAGATGCAGGTGGAGATGAACGATGTGGAGAGCACGCTGCATGGCATTCTCAACGAGATGCAGGATCAGCATCTCTACACGCCCGTCTGCACGCCTATCGATGAGTTCCTGACACCCGCCGACTATGCGCCGCTCGGTGCAGACTCGGAGTCGGCGCCGCCAACGCCAGCGAATGCCACCGATCTCTACCACGAGGCGGGCGTGgtgaagcagcaacaacagcagcagcagcagcaggtgaaGGAGGGCAATCTGTTCGACAGCAGCAACTTTAGCAATGAGCTGATTGGCTTCCAAAACGATATGCCCTGCTTCGAGAACATTGAGGCCTCGCCTGAGTCGATGGCGGCGCAGCAGAgtctgcagctggagctgacGCAGCTGCTGGACGATTTGCAGCCGCCCATcggcaccagcaacaacagcagcagcagcagcagcagccagcaacagcagcagcaaccgcaatTGCTGCAACCGGAGACTATCAGCTATGACGCACTGTATCCCacagcgccagcagcaacgCCAGTAACGACACCCGGGTCGCCGCTTTCCGACAATGGTTCGAGCAAGCTGCAGCTCATCCAAATGCAGCCGCAAGAGCCGCTGTGGCAAGCACAAGCTGCCGCTGCAGTCGCCGCTGCAGCAACTCACCAGACGACACATTTGCAATGGTCAACGGTGGGTGGCCTCGAGGCCGTCAAGACGCTGCCGCCCGCCAATTTGGACAGCGCGgcgacaactacaacgacgTACTACATCAATGCCAGTGATCTCTACCAGCAGTCGGGCAACTTGGCCAGCGACGGCTACGCATTGCTGGACAACAATGAGAACTACATAatggagcaacagcagcagcaacagcagcagcaacatcagcagcagcagcaacatcagcagcagcagcagcagcaacccaTTATGATACTCATACAGCAGCcagagctgcagcagccggTGGCATCAGCGAGCAACCCGCAGCAGGCGCCGTTGCACATCACCTATGGCCCAACGCTGGCCAACGAGCTGCACGGCTatcagccacagcaacagcaacagtcccaacagcagcaacagcaggcggtgcaacaacagcagccgccaccacaacgccagcagctgcagcagcagcaacaagtacaaaatcaaaatcaaacaGTATTAGGCTTGCCAGCACTTGTGGCGCCACCGCCACCTCGGGGCAGGCCGCCAATGTTGAAGTGCCGCTTCTGTCAGAACGGTCCGCGCTTCTCGAACAGCTTGGAATACAGTCGTCACATCATCGAGCTGCATCCCGCGGTGGCGCCCTTCAACTGTCCGCACTGCCCGCAATCGTTTGCCGGCCGTAGCAAACGCAACCAGCACATCTTAAGCCATCATGTGGTGCAGCAATTCCATTGCGGCCAGTGCTCCCAGATGTTTCCCGCTCAGCGAGCGCTCGACTTGCATCTGCAGCGCTTCCACATGCCACTCACAACAGACGCAGCCGGCGACGGTGTGCGGCTAGAGGAGGTGCAGCTCCAGATAGCAAGccaggagcagctgcagcaacagccacaatcGTTGCAACCATCGGCACTACTGGCAGCACTTCAACAGCAGAAGAGTCCGTCTCCGCCTCAGCCACGCAGGACTCGCATCCTTTGCTGCCCCGACTGCGAAGAATGCACGTCTGCAGCTAGCCATCAGCATCGCAAGGAGCAGCCTTATGAGGAGCTCAGCAATTTGCAGCCGCCGCCCACAGTGCTGACGCCACCCTCGACAATTGCGTCGCTGCCCTCGCCGCAGCCTGTGTGCCAAACGCCCCACATCACGCTGCCCTCGCCAGAGCAATCGGAGCCGGATTCGACAACGGCGACACTGCGACAATTCCGTAAACGCTGCGTGCCCACAGGCAGTGTCATTGCGATGCCTACGACGACAACAGCGGCCCCCACAATGCTAATCACGgcagcgtcgccgtcgccctcctcgtcgccgtcgtcatcGACGATGGAGAACAGTGCAACGCTGCAGATGAGCAAACTACGCGGCAGCCATCAGTGTGTGGTCTGCGACAAGCGGTTCACCAACATCATTGCGCTGCGCAAGCATCAGCAGCTGGCCCACGACTCGCAGACTACAATGCCGTGGGTCTGCTCGATCTGCAAGCGGGGCTATAGGAAGCGCACCGACATGGACAATCACATGAAGTCGCACGAGCCAAAGGGACGACCTTACGAGTGCAATGAGTGCTGGGTGCGATTCCCCGAGTTTAAGCAGCTGGCGATGCACAAGTTCACCGTCCACGAGCTGATCAAGCCGCATACGTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAATTTCATGGTGAGCGAGGCTTCCAGTGCGAAGAATGCGACGAGTCATTCTCAAATCTCAAAGAGTTTCGCAAGCATCGACGCACCCACAACAGAGAACTGTTTTACAAGTGCGAATACTGCCCACGTACTTTTCTGCATTTTACGAGCTTTCGTGCTCACATGAACACACACTTGCCGCTGGGCGTATTTCTTAACGATAAATCAACGGCTCAGCTGCCCAGCTGCCCCAAGTTGGAGTCTCCCGGCAACGAGGAGTTGATGCCACTGACGCCGCTGAGCAACGTCCACAGCGGAGGCAGCATCAGCGAAGACTGCCCCGGTTCAGTTGAGATGGTTGAGAGCAGCGTGGGCCAATCGCTGGAGATGATCATCGATACGCCGTAA
Protein Sequence
MVAKFRRRCVRVQQRLQEYAQQIAQRQARLDKETNNQAITNLPESQPERKRRLEESPTVQSEASSPKLKRRNVPHLATTMTTRNSKSRSPCKRINKPWRTKAARKQLSETWSTSSSSCLTTERSAATTAPVSNCSSSTSSSSGQTTPEHLSDLSVNPCRGFPSDGNSSTSLTNSDGQTTSPSKAKLQFPPKRAQIVMRRRRRLSTPVKRAKRIVRKTSEMTKDAPIKELNIKPEAELSNEHTKLADEAHLNNNSEEALSSSTDESSTASCGTEGAEEDDSKMTEIEKDPKAENNTEEETMPNEQLQSPAKVINETTETLREEATETTAAEEEIEQAVTPVQFEELTSSTEQMAPGVPSPECEVEVSMTSANELIVSIPLEALDDELQHKLCNAEPEAETEPEREEGEKGAAAGKENGEIDDVNNNANVEHFCQSATADSFNSAVALETKEIEAEPDGGGVDGGGGGGGVDDDMASLESLVELPKQTVEEPLPTRPAASSMDFLAEFEKHCEKTLKQQAAPCELELEEAKQQMQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYAPLGADSESAPPTPANATDLYHEAGVVKQQQQQQQQQVKEGNLFDSSNFSNELIGFQNDMPCFENIEASPESMAAQQSLQLELTQLLDDLQPPIGTSNNSSSSSSSQQQQQQPQLLQPETISYDALYPTAPAATPVTTPGSPLSDNGSSKLQLIQMQPQEPLWQAQAAAAVAAAATHQTTHLQWSTVGGLEAVKTLPPANLDSAATTTTTYYINASDLYQQSGNLASDGYALLDNNENYIMEQQQQQQQQQHQQQQQHQQQQQQQPIMILIQQPELQQPVASASNPQQAPLHITYGPTLANELHGYQPQQQQQSQQQQQQAVQQQQPPPQRQQLQQQQQVQNQNQTVLGLPALVAPPPPRGRPPMLKCRFCQNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPQSFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRFHMPLTTDAAGDGVRLEEVQLQIASQEQLQQQPQSLQPSALLAALQQQKSPSPPQPRRTRILCCPDCEECTSAASHQHRKEQPYEELSNLQPPPTVLTPPSTIASLPSPQPVCQTPHITLPSPEQSEPDSTTATLRQFRKRCVPTGSVIAMPTTTTAAPTMLITAASPSPSSSPSSSTMENSATLQMSKLRGSHQCVVCDKRFTNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFQCEECDESFSNLKEFRKHRRTHNRELFYKCEYCPRTFLHFTSFRAHMNTHLPLGVFLNDKSTAQLPSCPKLESPGNEELMPLTPLSNVHSGGSISEDCPGSVEMVESSVGQSLEMIIDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509359;
90% Identity
iTF_00509359;
80% Identity
-