Dust005204.1
Basic Information
- Insect
- Drosophila ustulata
- Gene Symbol
- Hivep2
- Assembly
- GCA_035047365.1
- Location
- JAWNPT010000057.1:36896820-36905581[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 4.1e-05 0.0028 18.1 0.5 1 23 222 244 222 244 0.98 2 8 0.00031 0.021 15.3 2.9 1 21 250 270 250 274 0.89 3 8 0.028 1.9 9.1 0.1 1 19 922 940 922 943 0.93 4 8 2.8e-06 0.00019 21.7 2.0 1 23 1654 1676 1654 1676 0.99 5 8 1.2e-05 0.00079 19.8 5.3 1 23 1682 1706 1682 1706 0.92 6 8 2.2e-05 0.0015 18.9 3.5 2 23 2165 2186 2165 2186 0.97 7 8 0.0008 0.054 14.0 1.2 1 23 2192 2216 2192 2216 0.91 8 8 0.0026 0.17 12.4 2.7 1 23 2237 2261 2237 2261 0.92
Sequence Information
- Coding Sequence
- ATGACGCTTCagcatgtggcaagcagcgcagcagcagctgtggaCACGACCACAAATCATGTGGTTGCCGGCAACGGtgcagcaatggcaacgggTGTTGCCAGCAGCGACGAGGCAACCACGGCGGCAACAATTGCCGATTGGACGAACACAACCAATTTGCGCTATCTGCACAAGAAATTCAAACGCGTGGCCAGCACCACCGAGGCAGAGGCGGCAGCCGATGCGGTGCGCACCACATCGTTGTCATCCAACAGTTCCCTTTCGCCACCaccgccaacagcagcagcgccaacagTGGTGACAGTGTCAGTGCCATTGCTCAATGGGCATGAATTCagtgccagcagcaacaacaacaacaataacaacagccatgaggagagcaacaacaacagcagcagcaagcatgttgctgctgcgcccAGAACGCGCACTCCTCTCaccaatagcaacagcaacaacaacagcaccagcaactATGCCAGCAATGCAACATTGTCGCCAGCAACATTCgcacagcatcagcaatcgacacagccaacagccacagcaacaaccgctgctGTGGCCACGGCAACAATTGCCCCAGCCAcagtgcagcaacagcaagcgattgcagctgcagccacaAGCAACTCACCTGCCGAGAAGCCAGGGCGCTACGTGTGTCCCTACTGCAACATGAGCTGTGCCAAGCCATCGGTGCTGCAGAAGCACATTCGTGCGCACACCAACGAGCGTCCGTATCCCTGCGACACCTGCGGCATTGCCTTCAAGACCAAGAGCAATCTCTACAAGCACTGCCGTTCCCGCTCCCATGCGGCGCGCCTGCGCGGCTTCGACGTGCCCGCCAACGAGGCGGACGGCCTGTCCGATCAGGACGGCGACGGCGAGCTGAGCAACAGCAGTTCCGAGCTCCTAAGCGTCGAAGTTCTGAGCCGTGCAGAGTCGCCCTACGACGAGCCGATGGCGTCGCCAACGCCATCGCCCTCAACGCTGTCGGCGGCAAAGAGCGCCTACCTGCAACAGCCGCCGTTGCCGCAGCACATGCAACAGTTGCCGCTGGGCTCGCCGGCAGCCGGCACGCTGCCGCCGCCAACAGCCGACACGCTGCACTCGGCGACGGCGCAGCATCGTCAGTCGATTGATTACAAGCCGTACAAGCCCAAGTTTCACAATGCCGCGCTCTACGCgcctggcagcagcagcaaggagcagcaagtgcagctgcaagtgctgcaacagcagcagcagcaacaacaccagcagcagcaacaggcattgcaacaccagcaacaacaacagcagcagcaacaaaagttattgtcacagcagcagcaacaacaaccgacGTTGGCGCATCCAACGCTGTCGCCCAGCacgcagctgaagctgaacaATCACATCAACTCGCATCagatgcaactgcagctgcagcatcagcaccagcagcaacaacagcagctgcacgCACAGCAATCATTGCTGCTGGCCGCAGCCGCCAATCCAGCGGCATTAACTGGATTGCCGCCACCGCCGGCGATGCCCACGAGCGTCTACTTCTTGGGCCAGCCGCAGTATTTCAATCCAGCGACGGCCGCAATGCATCAACAGGCGCTCGCCTTTCACCAGATGCAGTTCCAGCAGCACCTGCAgctccagcaacaacagcagcagcagcaacaacaacagcagcagcagcaacaacattcgCCGCTGTTGAAGGCGCCAACGCATCAGCCGCCACCGCAGCCGCAACCGCAGCCCATGCAACAGCCGCCAAtgccgcagccacagcagCTGATGCGCTCAAACAGCCAACagacgccagcagcagcagcagcggcgtcgCTGCCAgcccctgccacgcccacgccagCAGCCAATCTGAGCAGCTTTGCCAGCGCCAGCGGCGGCATGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCGAAACTGATCTCACAGAACGAGGCCATAGTGGAGAACAAGGAGATTCTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGCTCGCGCAGCTTcaacaatgccaacaacagcaacagcaatgccaacagcagcagcaacctcaacagcagcagcgtcatcaacgtcaacagcaacaacagcagcagcagcaacaatgcagCGCAGCTGGGCGAGGCGAAGGTGAATCTGGCGCAGGCCATAGtccaaaagcagcagcaacagcagctgcaacaacagcagcagcagcagcaacagttgctgcaacagcagcaataccATCAGtacatgcagcagcagcaacaacagcagccgcattTGGAGCCCGTCAATGGTCTGCtgaagcgcagcagcagctccaacgGACCCTACGCTCTCAAGGTGTTGCCCACACCGACGGCCACGCCTCTGTCCACTGccaagctgcagcaacagctgccgccgcctcccTCGCCATTGCCGCTGCAGACGTTGCAGTATCGCCAGGATCCAGCAACGCCGGTGCCcaagctggagcagcagccacagcaggcGACGCCCAATCATGTGCAGCCACTGAATCTATCCGCCAAACCCAAGCCTGCGGCGCCATCGAAGCCAGCGCCAACGGCCGCcaatgtggcagcaacagcagcagcgccaagtGCTGCAGCCGTAGCGAAGAGCGCAGCGAACGCGATGCAGCAGTCGAACAACTCAATCATCAAGAATCTGCTGCTGAATGCACGCGGTCTGGCGGTGCCCATTGGCGAGGGCGACGATGCCGTCTACTCGTGTCCCATCTGTGCCAACGAATTCCGCAGCGCCGACGAGCTGAAGCTGCACAACAGCACCTACTGCCAGGATGCGAGCAGCAGTGCCCCAATGAGTCCCGCCTCGTCGCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTCAGTTTGCCGGAGCTCAAGTCGCACATGGCCAACTCGAAGAATCCGCTGTCGCTGGCCAAGCTCGCCTGGTCGCAGCTCAAGACGAAGCCCAGCAGCCTGGTGCTGAGTCGCCTCAGCGCCGCCCAATCTCCGGCTCGCACCTCCACAGTCACCgccagcagcagtagcagcagcagcagcaacaacagcaatctggttaatgttgctgctgtgcagcCGCCCAGCATTGATGCCAGCAATGTTGCCTTGAGATTTGTGGATGCGCCGTTGCCGTCGCCAGGTCCGCTGCTGGGCAAGACGCCGCTGGTGGACTATGCGGCGCCGCGCAAGACGCAGGACACTCAGGTGGTCATCACCAAAATGCACGAGGATCGCGTGGAGAACATTATCGTCGAGGCGCCCGCCAAGCGTGCCAAGCTGAGCAATGATCTGGGCAGCAGCGGCACCGCCTTCGCCTTGCCCTCCACTGTGCAGCTGCAGATGTTTGGCGGCAACCAGGAGCTgcagccgagcagcagcagcagctacagcgCCAAGGAGGAGCGTCTGCGTCGCTTCACCTCCTCCGGCGGCACCATGATACCCATCTCCGAGTGCCCCGAGCTCAACAACAGTCCCAAGATGATACGCACGCCGCTGCTCTCCGGCGGCAGCTTCCAGGAAATGTCGCCACGACTCGCCGAGGCCAAGGAACGCAAACTGTCGTCCAATCCAAACAATGGCTTTCTACTCAACACTGCAGCCTCGACGACTCCGCAGCACTTTCAGTTTCCGCCCATCAACTCGATCACCGCCTTCAACCCCTTGACGCTGCCGCccatgagcagcagcagcagcagcaacctgGCGGAGTCCAACAAGGCCATTCCCTATGTGCCGGGCATTCCGGGACCCGGCAGCctgtcgctgttgccgccgccgcagcagctgcagctgcccagCGTGGCACGTGGCCGCAGTCCCAATCGCAAGCAGCCGAGTCCCAATCTGCTGCTGGATGTGCCGCTCAAGGCCTTGTCGCCGTTCGGTGGCGTGCAGAATCTGCCCAGCGAGTTCAGTCGCCAGCCACCGACGCCCGCGCAACGCAATGCGCTGCACtggagcagcggcagcagcagcagcaaggcggcaacagcagcatcgacAGTTGCCCCCGCTGCCGCAAAGCAGCCATTCAATTTCCTGCGCATGGCGGACAACGTGAAGGCAACGCCGGATCAAACGCCgcccgctgtcgctgccgttgccgttgcggTGCCGGAGGTGCGACACTTTAACTTCGACAATGTGCACAAGACGCAGCAGGAGGCGCTGGCGCCTCTGCACGTGGAAACACCAGAGGAGGCAACCACAACGACGACCGCGACCACAGCCAGCGGGAATGCGGCGAAGTCCAAGTTTCTGCGCCCCACCAGCCTGCCCCTCAAGCCGGGCACGTTCACGCCCAAGCGTCATCACGGCATCACGCCGACAGCGAACACgctgcccctgatctcaccgGAAACCCCGCGGCCCTCGAAGTCGTGCGTGCAGCTCTATCTCAATGGGCACGCCTACACCTATCTGGGTCTCAAGTGCAGCACCAAGATGTTCTACTGCACCGTCAACTGTCCGCAGCCCTCGTACGTCGCCGGCATGCACAAGCTGTCCATGTACAGCGTGTGGCAGGTCTGCGAGGAGAACCAGCCGCATCCGCTGGGCTTCAAGCCCAAGCAGGTGATGGCCCTCTATGATTCGCGCCAGAAGCTGCTGGGCAGCGGCTCCTCCATGGCCATGGCTGGCGCCGGCAAGATGCTCTACTCGGTGGTCAGCTCTCAGCAGACGGTGAGCACCTGTTCCACGGTGGCCAATGGCCAGAACAAGTTCTATCAGCATCAGCCGAAGCAGGCGACGCCGGCGATTGCCGCGCTCAGCGAGGCGAATGTCGCTGCCAAGGCGAgcgaggaggcggcggccaaGAAGCTGGAGACGGGTCAACTGCTTGTCGGCGGCTACGAGTCGCATGAGGATTACACCTACATCCGGGGACGTGGACGCGGACGCTACGTGTGCTCCGAGTGCGGCATTCGCTGCAAGAAGCCCTCGATGCTCAAGAAGCACATTCGCACGCACACCGACGTGCGTCCCTTCACCTGCAGCCACTGCAACTTCAGCTTCAAGACAAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAGTGCATCGAACTGGGCATCAATCCGGGTCCCATGCCCGCCGATGGCGAATTCCTCGACGTCGACGTGGAGTTCGATCAGCAATCCTCGACGTCAGCGGGCGGACGCACTTCCTCCATGGCCGGCGAGTCGGACTCCGATGACTACAGCGACAACGAGTCCGAGAGCAGCGACACAGACGAATCGAAGTCGCGCCAGAAGGAGCACGAGGCGGCGCGTGgcctgctgtcgctgtcgatgACGCCGCCCATACCGCAAAGCGTTTCGCCGTATCCGGCGCAGCTGCAGGAGACGCCCGTGCCGGCCGCCAGTCCGGCCAACAGCATCGGCTCCTCggcgggcagcagcagcgccgctGGCGGCTCGCAGCCCAAGCGTCTGATCTGCTCGTTCACATCGCCCAAGCCGCCGTTCGACTACCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCGAAGCCCAAGCGTGGCGTACCCAGCGACGAGAGCAGCGCACCCATGGACCTGACCAAGCCACGCTCCTCGGCCGCTCCCATTGCTGCCGTGCTGGCGTCGCCGCCCGTGGAGCAAGTGCTGCCCAAGTCGCAGGCCCAGCAGATGCGTGACGTGATCTTTGGCACGGGCAACAACGAGTGCGGCTTCATGAAGACGCTGATCTCGGTGTCGGACAAGGTGCGCATCTCCGCCGAGATGGAGGAGCAGGCGAAGCGCGACAACGAGGGCGGCGACGATGTGCTGCTGCAGACCTACATCAAGGAGCAGGCGCTGCAGTACGCCAAGATGAAGCAGAGCCAGTTCAGCCGCAGCTACCTGACCACAACGAGTGCCTGTGGCAGCATCATCAccaccagcagctgcagcagctccacCACCATTGTCAGCAGCAGTCTGCACAAGCCCATCATCATCACAGAGCTGCCCAGCATTGAGGTGCACGAGGTGAAGACCCCCGAACCGGAGGCAGCCCCATTGCCAGTCAAGACAGTGGTCGAGGAGCCGAAGGAAGCAGAGCCAACGCCAGAGCAGGAGCAGCCAgcggcaacagttgctgtCAGCACAACTGTGGTTGTGTCGCAGCCAGAGCCACAGCCACACAACGCCAATCTGCCGGCTGCAGTGCAGCAGCCAGATGCCAACGACTTCAGCGGCGTGCTCAGCGGCAGCAAtgcgacgccagcagcagctgctgcgccaGCGGCACGCACCGTCATCGTGGGCGAGGAGGGCTTCAAGACGACGCCGCCAACGAGCAGCGCCGCAACGGCGGAACTGCCGCCAGCTGCCGTCTCCGTGGCCGCCTCCAGCAGCTTTGCGGGACGCGTGgggccgccaccgccgccgccgatcGCCAGCGATGCGCGTCCCACGTGCAGCATCTGCAACAAGACGTTCCAGCGACAGCATCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTTCGCACCCAGGGCCATCTGCAGAAGCACGAACGCTCCGAGGCGCACAAGAACAAGGTGATGATGACGTCCACGTTTGGCGTGCCGACCACCTCGAATCCGCGCCCCTTCGAGTGCACCGACTGCAAGATCGCCTTTCGCATCCACGGTCATCTGGCCAAGCATTTGCGCTCCAAGACGCATGTGCAGAAGCTGGAGTGCCTGCAGAAGCTGCCGTTCGGCACCTATGCGGAGATCGAACGCGCCGGCATCAGTCTGACCGAGATCGATACCAGCGACTGCGACAATTCGCTGATCTCGCTCAAGTTGCTGGCGCAAAAGCTGCTCGAAAAAGATCCCAACAAGCTGAGCAGCTACACAACGCCGTCGGGCATGCTGCAGCTGGGCTCGGATGCCCCGGCTGCGGGTCAAGACAGCGCCTCCGAGGATGGCTTCAGTGCAGCGAACAGCGCGGCAGCCTCAGCGATTGCCTCGCTGGACAACGACAGTGCCGGCAACACGCCACAGCGTGCCAGCTCCATGAGCGAGGATGAGACGCTGGCCAACGGACTGAGTCACAGCCTGAAGCGTCGCCTGCCCGGCAGCAGTTTCAGCAGCAACGGTGACGAGAGCGACAATCCGCTCGAGGGCGCCGAGAAGCGGGCGCGCAGCAACACCAACGAACTCAATCTGccgTACATGTACATGCTGCAGCCCACCTGA
- Protein Sequence
- MTLQHVASSAAAAVDTTTNHVVAGNGAAMATGVASSDEATTAATIADWTNTTNLRYLHKKFKRVASTTEAEAAADAVRTTSLSSNSSLSPPPPTAAAPTVVTVSVPLLNGHEFSASSNNNNNNNSHEESNNNSSSKHVAAAPRTRTPLTNSNSNNNSTSNYASNATLSPATFAQHQQSTQPTATATTAAVATATIAPATVQQQQAIAAAATSNSPAEKPGRYVCPYCNMSCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARLRGFDVPANEADGLSDQDGDGELSNSSSELLSVEVLSRAESPYDEPMASPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPPTADTLHSATAQHRQSIDYKPYKPKFHNAALYAPGSSSKEQQVQLQVLQQQQQQQHQQQQQALQHQQQQQQQQQKLLSQQQQQQPTLAHPTLSPSTQLKLNNHINSHQMQLQLQHQHQQQQQQLHAQQSLLLAAAANPAALTGLPPPPAMPTSVYFLGQPQYFNPATAAMHQQALAFHQMQFQQHLQLQQQQQQQQQQQQQQQQHSPLLKAPTHQPPPQPQPQPMQQPPMPQPQQLMRSNSQQTPAAAAAASLPAPATPTPAANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNSNSNANSSSNLNSSSVINVNSNNSSSSNNAAQLGEAKVNLAQAIVQKQQQQQLQQQQQQQQQLLQQQQYHQYMQQQQQQQPHLEPVNGLLKRSSSSNGPYALKVLPTPTATPLSTAKLQQQLPPPPSPLPLQTLQYRQDPATPVPKLEQQPQQATPNHVQPLNLSAKPKPAAPSKPAPTAANVAATAAAPSAAAVAKSAANAMQQSNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKLHNSTYCQDASSSAPMSPASSPSSKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTVTASSSSSSSSNNSNLVNVAAVQPPSIDASNVALRFVDAPLPSPGPLLGKTPLVDYAAPRKTQDTQVVITKMHEDRVENIIVEAPAKRAKLSNDLGSSGTAFALPSTVQLQMFGGNQELQPSSSSSYSAKEERLRRFTSSGGTMIPISECPELNNSPKMIRTPLLSGGSFQEMSPRLAEAKERKLSSNPNNGFLLNTAASTTPQHFQFPPINSITAFNPLTLPPMSSSSSSNLAESNKAIPYVPGIPGPGSLSLLPPPQQLQLPSVARGRSPNRKQPSPNLLLDVPLKALSPFGGVQNLPSEFSRQPPTPAQRNALHWSSGSSSSKAATAASTVAPAAAKQPFNFLRMADNVKATPDQTPPAVAAVAVAVPEVRHFNFDNVHKTQQEALAPLHVETPEEATTTTTATTASGNAAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKLLGSGSSMAMAGAGKMLYSVVSSQQTVSTCSTVANGQNKFYQHQPKQATPAIAALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYPAQLQETPVPAASPANSIGSSAGSSSAAGGSQPKRLICSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPSDESSAPMDLTKPRSSAAPIAAVLASPPVEQVLPKSQAQQMRDVIFGTGNNECGFMKTLISVSDKVRISAEMEEQAKRDNEGGDDVLLQTYIKEQALQYAKMKQSQFSRSYLTTTSACGSIITTSSCSSSTTIVSSSLHKPIIITELPSIEVHEVKTPEPEAAPLPVKTVVEEPKEAEPTPEQEQPAATVAVSTTVVVSQPEPQPHNANLPAAVQQPDANDFSGVLSGSNATPAAAAAPAARTVIVGEEGFKTTPPTSSAATAELPPAAVSVAASSSFAGRVGPPPPPPIASDARPTCSICNKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCDNSLISLKLLAQKLLEKDPNKLSSYTTPSGMLQLGSDAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLANGLSHSLKRRLPGSSFSSNGDESDNPLEGAEKRARSNTNELNLPYMYMLQPT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00509296;
- 90% Identity
- iTF_00520831;
- 80% Identity
- -