Basic Information

Insect: Drosophila ustulata
Gene Symbol: zfh1
Assembly: GCA_035047365.1
Location: JAWNPT010000094.1:25902864-25930865[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0063 0.42 11.2 2.1 2 23 76 98 75 98 0.96

2 9 0.00061 0.041 14.4 0.1 1 23 300 322 300 322 0.97

3 9 1.6e-05 0.0011 19.4 0.6 2 23 336 357 335 357 0.97

4 9 5.9e-05 0.004 17.6 4.9 1 23 366 388 366 388 0.99

5 9 0.00024 0.016 15.6 1.4 3 21 396 414 394 415 0.94

6 9 0.03 2 9.0 0.4 2 21 656 675 655 676 0.92

7 9 1.5e-05 0.001 19.4 0.5 1 23 1028 1050 1028 1050 0.94

8 9 5.6e-05 0.0038 17.6 7.4 1 23 1056 1078 1056 1078 0.98

9 9 0.0028 0.19 12.3 4.3 1 21 1084 1104 1084 1105 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0063	0.42	11.2	2.1	2	23	76	98	75	98	0.96
2	9	0.00061	0.041	14.4	0.1	1	23	300	322	300	322	0.97
3	9	1.6e-05	0.0011	19.4	0.6	2	23	336	357	335	357	0.97
4	9	5.9e-05	0.004	17.6	4.9	1	23	366	388	366	388	0.99
5	9	0.00024	0.016	15.6	1.4	3	21	396	414	394	415	0.94
6	9	0.03	2	9.0	0.4	2	21	656	675	655	676	0.92
7	9	1.5e-05	0.001	19.4	0.5	1	23	1028	1050	1028	1050	0.94
8	9	5.6e-05	0.0038	17.6	7.4	1	23	1056	1078	1056	1078	0.98
9	9	0.0028	0.19	12.3	4.3	1	21	1084	1104	1084	1105	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTTCACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCGTCCAGTCTGCATCACCATCAAGCACACAGCAAGCCCAGCAATGTGGCTGCCAGTGAAGAGCTTGCCACGCATGCAAGCAGCGCCGCAGCGAATGCGGCAGACGACTATTTGGTCAAGTGCACGCAGTGCCACAAGCGCTTCAATGAGTTTCAGTCCCTCAGCGAGCACATTGCCCGCGAGCATCCGCACGACAAGCTCAATTACGAGCCCCTGCGTCAAGCTGGCGCTGCGCAGCCGGAAAGCGATGCCGAGGAGGATGAGCAGAGCAatttgagcagcagcagtcgacgCTACAACAAATCGCCctcgaacaacaacaacaacaacaacatcgaaacagccaaaaatcaaaacaacaacagccagcaacagcagcaactaaaTTCGCCGCTCTGCTCACCTGTTGCCcaagcacagcagcaacagcagcagcaacaaccgccTCCCAGCGATCTCTTTGCCCATCTGCCGCATCCTCCGCCCCAGCTGCCCGCCCATCTGCACGCTCAGTTCATGGCAGCCGCAGCGTTGGCCATGCAATCCGCACGCTCCGCCAGCTCGCCCAGCCACCCGCTACATcatcaccagcaacagcaacagcagcagcagcagcaacaacagcagcagcagcaacagttgccgcaaCAAGGCGgacagctgttgttgccaccgcCGCAGacgggcagcaacagcagcgtggGCAGCAATTCGGCCTACGAATTGGATCTGAGTGCTCCACGTTCCACATCGAGTCCGGGCTCCACGACGGGCGATCTCAGCGCTGCCTTTCCCTGCATGCAATGCACGGCGGCGTTTGCCACACGCGACCAACTCGAGCAGCATCAGCTGCTGCACTCGCCCACAGGACAGCAGACGACACAGAATGTGGCACAGACTTGCAAGATTTGCAACAAGGCGTTCGCGAATGTTTATCGACTGCAGCGTCACATGATCAGCCACGACGAGTCGGCGCTGCTGCGAAAGTTCAAGTGCGGCCTCTGCGAGAAGGCCTTCAAGTTCAAGCACCATCTGAAGGAGCACGTGCGCATTCATTCCGGCGAGAAGCCTTTCGGCTGCGACAAGTGCGGCAAGCGATTCTCGCATTCCGGCAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAGCagaacaacagcaatcacaacagcagcagcaacaacaactccaacTCGAATTCGCGACAATTGCTCAAGAGCATGGATAAAAACGGACGCTCGCCAACGGAACAATTGCAGAACAAACGCGGCTGCAAATTGCCCATCGAGGCCACAAATCCTTTGGTGCCCAATCCGATGAACTACTTTGCGGGCGAGGCACAAAATCCACCAACAACTGGAGTAGCAGCTGCTGTCAATCCAGCCTCGTTCTATCCCAACTACAGTGCGATGAGCACGGCGCTGTTGGCGTTTCCCAATGCCTTCATGGCTGCGGCGCTCGATCCGCGCATGCATCCCTACAGCATACAGCGACTGCTCGAACTGTCGGCggcccaacagcagcagcagcaacaacagctggagcagcaacagcagctggagcagcagcaacagttggaGCGACAGCCGCTCTATGAGGCCAGCAAGCAGGAGGAGGAAACGCCCGATGAGCCCAAGTTGGTCATGGATCTGGAGGATGCCGAGCTGAAGCCAGCGACGCCCGAGTTGCCGCCCATCGAGTCCAGCGTGCCGCTGAAGCAGGAACCAAGTCGCGAGGCGACGCCAGCGCTGCTGGAAAGCGCGCCCGCCACGCCGCAGAACATCAAGCAGGAGCAGCCAGAGCCGCAGGAGCCGGAAGCGGAGCTGGAGCCGCAAGAGCTGCGCTGCAGTCGCTGTGCCAAGCAGTTCAATCATCCCACAGAGCTGGTGCAGCACGAGAAGGTTCTCTGCGGCCTCATCAAAGAGGAACTCGAGCAACAttaccagcaacaacagcagcagcaacaacagcaacagcagcagcaacaatcgaGTTTTGTGCTGCCCAGCGATGCGGatgaggacgaggaggaggactGCGAGGAGCCGCGTTCGATGCAGGATTACAAcgccggcggcagcagcgacagcggcgaGCGTAAAGTTCGCGTTCGCACCGCCATCaacgaggagcagcagcagcagctgaagcaacATTACGCGCACAATGCGCGTCCCAGTCGCGATGACTTTCGCCTGATTGCCACTCGGCTGCAGCTCGACGCACGCGTGGTTCAAGTCTGGTTCCAGAACAACCGTTCGCGCGAGCGCAAGCTGCAAAGTTATTCCGGCGAGCCACAAGTGGCAGCCAACGCAACGGCAGCcaatgcaacaacagcggcagctgcgCCGGCCGCCGATCAGCCGCTGGATTTGTCTGTGAAGCGCGACGCTTCGCCGCTTTACGGCTTGGCGCCGCAGCCCAGTGGTTTGGGTTCGACGCCCGCTGATTTTCAAGACAGCATCGCCATCAATTTGAGCCGCAAACTGTCCAGCTCGGCCTCGATGTCGCCGGCCTCGTTGTcgccctgctcgggcgcctcCTCGTTGCAACAAACTGCAGCCGCTGCGGCCGCTGCAGCTTTGTACTTTGCACCGCCCTCGCCGCCCAGCCTGCACGAGGCAGTGCCGCCTTTGGCGCCTCGTGGCCAACCCTTTGCCCAGCTGCCGTCCTACTTGATGCCACGCCTGCCCATGGAGGCCTTGTTTCAGATGCGTCCCGGCGGCGACTATGCGCCCAATCCGCTGATGAACAGTATTAAGCTGCCCGACTTCCGCGGCACGAGCCTGAGTCCCGGTGGCAGCGAGAAGCGTTCGTGGCGCGACGACGATTCGCGCATCTCCCACGAGGACGATTACGTCCTGGCTGCTGCAGCGGGCAACGGCGGTTTGTTGCCGCCCAAACCGAAGCGCGCCAAGGCGGAGACACACGGACATGCCGGCGATCCGGACTTGCCGTTCGTCTGCGATCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCGCTGGCGCGCCACAAATACGAGCATTCCGGTCAACGACCCTACCAGTGCATGGACTGCCCGAAGGCCTTCAAGCACAAGCACCATCTGACGGAGCACAAGCGTCTGCATTCCGGCGAGAAGCCCTTTCAGTGCTCGAAGTGCCTGAAGCGCTTCTCGCACTCGGGCAGCTACAGCCAGCATATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQAHSKPSNVAASEELATHASSAAANAADDYLVKCTQCHKRFNEFQSLSEHIAREHPHDKLNYEPLRQAGAAQPESDAEEDEQSNLSSSSRRYNKSPSNNNNNNNIETAKNQNNNSQQQQQLNSPLCSPVAQAQQQQQQQQPPPSDLFAHLPHPPPQLPAHLHAQFMAAAALAMQSARSASSPSHPLHHHQQQQQQQQQQQQQQQQQLPQQGGQLLLPPPQTGSNSSVGSNSAYELDLSAPRSTSSPGSTTGDLSAAFPCMQCTAAFATRDQLEQHQLLHSPTGQQTTQNVAQTCKICNKAFANVYRLQRHMISHDESALLRKFKCGLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQNNSNHNSSSNNNSNSNSRQLLKSMDKNGRSPTEQLQNKRGCKLPIEATNPLVPNPMNYFAGEAQNPPTTGVAAAVNPASFYPNYSAMSTALLAFPNAFMAAALDPRMHPYSIQRLLELSAAQQQQQQQQLEQQQQLEQQQQLERQPLYEASKQEEETPDEPKLVMDLEDAELKPATPELPPIESSVPLKQEPSREATPALLESAPATPQNIKQEQPEPQEPEAELEPQELRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQQQQSSFVLPSDADEDEEEDCEEPRSMQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDDFRLIATRLQLDARVVQVWFQNNRSRERKLQSYSGEPQVAANATAANATTAAAAPAADQPLDLSVKRDASPLYGLAPQPSGLGSTPADFQDSIAINLSRKLSSSASMSPASLSPCSGASSLQQTAAAAAAAALYFAPPSPPSLHEAVPPLAPRGQPFAQLPSYLMPRLPMEALFQMRPGGDYAPNPLMNSIKLPDFRGTSLSPGGSEKRSWRDDDSRISHEDDYVLAAAAGNGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589739;
90% Identity: iTF_00520532;
80% Identity: iTF_00614091;