Dust003553.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ustulata
Gene Symbol
-
Assembly
GCA_035047365.1
Location
JAWNPT010000057.1:22347328-22350234[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 1.6 1.1e+02 3.6 0.2 1 23 288 311 288 311 0.95
2 9 0.27 18 6.0 0.7 2 23 360 382 359 382 0.92
3 9 0.0025 0.17 12.4 5.5 1 23 606 628 606 628 0.97
4 9 0.0009 0.061 13.8 0.5 1 23 634 656 634 656 0.97
5 9 0.001 0.07 13.6 1.3 1 23 662 684 662 684 0.98
6 9 3.7e-07 2.5e-05 24.5 0.1 1 23 690 712 690 712 0.99
7 9 2.7e-06 0.00018 21.8 0.4 1 23 718 740 718 740 0.99
8 9 1.3e-06 8.9e-05 22.8 1.1 2 23 747 768 746 768 0.97
9 9 7.6e-05 0.0051 17.2 1.0 1 23 774 797 774 797 0.97

Sequence Information

Coding Sequence
ATGCTAAAAATGACAAAtgtgccgatgccgatgccgacaATGCTTAAGCTAGGCAGCAGCGCAGGCACAAACACAACCAGCAGAGGccgaggcagaggcagcggcaacaacggcgcagcagcggcagcagcgaaaacaacaaaaaacgcaCAGCATAATGGAGTAGCAGCTGCGTCGCTGCGCAGCGcagccgacaacaacaacgataacgaCAACGACACGGACGAATCCGATGACTCCGAGTCGGAGCTGGATATCGAAGAGGAAGACGATATTTTGCttgacgatggcgatgacgatgatgttgTGCTCGACAGCGAGGATGAGGCTGAGTTGGAGGCGCAGCGCATACGCTTAGATGATTTGAAggccgccgccgcagctgcAAAGTCGCAGGTCAGTAACGGTAAAGacgcaactgcgactgcgacgcagccgaagcaaaaacaacaacaacaagaacaacaaggaaaacagaaacagcaggCGCCGCAGAAAACAGAGACCCGAAAGCCGCGTGGGCGGCCGCCCGGcagcacaaataaaaacaacaacaaaaaccagcgaaataaaaacaaacgcaaaaacacaaacagcGCCTGCGTCGGCGCaagcgtcgcagtcgccgcaGCAGGCGCAGTTGAGGCAACTGTTCCCGTTCCCTCGCCAGCTGCTGTTCCCACTGCTGTTACAGCTGCTGTTCCCTCGCCTGTTACAGCTGCTGTTCACACTACTGTTATTGCTACGGTTCCCACTCCCGCTGCTGTTCCCTCGCCTGTTACAGCAACTGTTCCCTCGCCTGTTCCCACTCCCATTGTTCTCGGCCAAATTCACGCAGATGAGAAGGCGCATCGCTTTATCTACAGCTGCGTCAGCTGCCCGCTGCTCTATGGCGATGCGGAGTCGCTCTCCCAGCACTGGCACAAGGAGCATCAGCAGCTGGAACGTCTAGAAGGCAAAGCTGAGCAAGAAGTGAAGTTGGAGCCGCCGCTGGAGCTCAACGATGGTCTCAAAGTGAGCGACTTGAAGTGCTGTGCTCATCTTTGGCTGACGGACGAGACGTCCAAGCAGCAGTTGCGCTGCGCCAGCTGCGATGCCAACTTCAAGCTGAGCAAGgagctgcatctgcatctgagCGAGGAGCATGGCATCTGCAAGCTGCTCGTGCCCAAGCGGGAGCCCAGCGAGCCCATGGTGAGCATACCATGCGAGGTGGGACGCAGCAAGTCCAGTTCGTTGCAGCCAGTGGAGCTGCCGGAGACGCCGCCGCCCGAGAAGGAGGTTGCGGACAAAGATGATCTCGCTATGATCTCCGCTATGGTGGCGGAGATAGCGGCAGAGCGCAGTCCCAAGGTCAGCAAGATGATCATTAAGCTGCCCGCGGTGGGCAAGCAGCGCGGACGCAAGCGCAAGAAGGGAGAACAACcaaagcagcagaagcagccgcaggaggaggcggaggagaaggaggaggagcaggatgCCAAACGCAAGCGAGCACGCAAGGTGCAAAAGGTGCCGGAGAAGGAAGAGAAGCAGGAAAAGCAGGCGAAGCAGCTGGAGAAGCTGGCGAAGGAGCTGCAGCCAGAGATCAAAGAGGAATTGGAGCCAAGACGTGCGCGCAAGTCGCGTGCTTTTGTGGACTACGTGGTGGATGTGAAGGACGAGGaggacaacgacgacgaagacgaggaggaggacaaAGACAGCGATTCGGATGTGGAGTCGCCACAGAACAGTTCCACAGACGACAGTCATGCCACCCCCTCGATCAAGCGCGAATCCTCCGAGGAATCGCAGCGCCACGGCACAACGCACACCTGCAACTTCTGCAGCAAAACCTTCCAGCGCTTCTCGCGGCTGCAGGATCATCTGCGTCTGCACACGGGCGAGAAGCCGCACGTCTGCGGGGAATGTGGACGCGCGTTTCGGCTAAAGATGCGTCTGGCCGAGCATCAGTTGCGCCATCGCACCGAGAAGGCGTTCAAGTGCGAGCTGTGCGATCGCCCGCTGGCCACCAAGCAGGACATGTCGCTGCACATGCGGCACCACAAGAACGATCGACGCTACAAGTGCGATCGCTGCGGAAAGGGATTCGTGCGCAGCTCCGATCTGGCCATCCATGTGCGTGTCCACACCGGCGAGAAGCCCTACAGCTGCGATCTGTGCGGCAAGGCGTTTCGCGCCCGCCAGAATCTCGTGGTGCATCGACGCACCCATCTGGGCGACAAGCCCATTCAATGCGAGCTCTGCGACAAGCGTTTTTCCCGCAAGATCGACATGCGCGTTCACATGCGTCGCCACACAGGGGAGAAACCGTTCAGCTGCAACGCCTGCCAACGTGGTTACTCATCGCGCGTCAATCTGCAGCGACATCAGCAGCGGGAGCATGGCGGCGAGACAAAGGCGGAGCAGCCCGCTGCGGAAGAGGTCAAGGCAAAGCCGGAGACACGTCGTCCGCGTCGCGAGAAGCTGCAGGAGAAGATTGCCGAGCAGGAGAAGCTGCTGGACGAGCTGAAGCGCAGTCTGAGCACGATGCCCGACATTGCCGAGGAacaaagcgaagcgaagccGGAAAGCAAAGGGAATATGACGGAGCTGGCTGCGGATGCGGGAGCAGGTGCAGGCCCGGCAGCGAGTGTCAGCTTGGCACAGGTGTCGGTGACGGTGTCGATGCAAGTGGAGCCAGCCAAGCcggatgacgatgacgaggaGATCACGCCGGAGAAGGAGAATGCGCGTCAGAGCGGCTCGACGGCGGACGCCGTGTCCGGCAGCGGCAAGACGAAGACTAATCGCAAGATAACGAGCTACTTTACGGTCGTTGGCCAGCAGGCGGAAATCTAA
Protein Sequence
MLKMTNVPMPMPTMLKLGSSAGTNTTSRGRGRGSGNNGAAAAAAKTTKNAQHNGVAAASLRSAADNNNDNDNDTDESDDSESELDIEEEDDILLDDGDDDDVVLDSEDEAELEAQRIRLDDLKAAAAAAKSQVSNGKDATATATQPKQKQQQQEQQGKQKQQAPQKTETRKPRGRPPGSTNKNNNKNQRNKNKRKNTNSACVGASVAVAAAGAVEATVPVPSPAAVPTAVTAAVPSPVTAAVHTTVIATVPTPAAVPSPVTATVPSPVPTPIVLGQIHADEKAHRFIYSCVSCPLLYGDAESLSQHWHKEHQQLERLEGKAEQEVKLEPPLELNDGLKVSDLKCCAHLWLTDETSKQQLRCASCDANFKLSKELHLHLSEEHGICKLLVPKREPSEPMVSIPCEVGRSKSSSLQPVELPETPPPEKEVADKDDLAMISAMVAEIAAERSPKVSKMIIKLPAVGKQRGRKRKKGEQPKQQKQPQEEAEEKEEEQDAKRKRARKVQKVPEKEEKQEKQAKQLEKLAKELQPEIKEELEPRRARKSRAFVDYVVDVKDEEDNDDEDEEEDKDSDSDVESPQNSSTDDSHATPSIKRESSEESQRHGTTHTCNFCSKTFQRFSRLQDHLRLHTGEKPHVCGECGRAFRLKMRLAEHQLRHRTEKAFKCELCDRPLATKQDMSLHMRHHKNDRRYKCDRCGKGFVRSSDLAIHVRVHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFSRKIDMRVHMRRHTGEKPFSCNACQRGYSSRVNLQRHQQREHGGETKAEQPAAEEVKAKPETRRPRREKLQEKIAEQEKLLDELKRSLSTMPDIAEEQSEAKPESKGNMTELAADAGAGAGPAASVSLAQVSVTVSMQVEPAKPDDDDEEITPEKENARQSGSTADAVSGSGKTKTNRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00520816;
90% Identity
iTF_00520816;
80% Identity
-