Basic Information

Insect: Drosophila ustulata
Gene Symbol: ham
Assembly: GCA_035047365.1
Location: JAWNPT010000118.1:306845-328626[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.59 40 5.0 0.0 2 21 361 380 360 383 0.87

2 9 0.0012 0.078 13.5 0.8 1 23 390 413 390 413 0.91

3 9 1.9e-07 1.3e-05 25.4 1.7 1 23 419 442 419 442 0.96

4 9 3.6e-07 2.4e-05 24.5 1.5 1 23 448 470 448 470 0.97

5 9 4.3e-05 0.0029 18.0 3.7 1 23 476 498 476 498 0.97

6 9 0.013 0.87 10.2 1.6 3 21 507 525 505 526 0.93

7 9 7e-09 4.7e-07 29.9 1.3 1 23 1020 1042 1020 1042 0.99

8 9 1.5e-07 1e-05 25.7 1.1 1 23 1048 1071 1048 1071 0.97

9 9 6.9e-06 0.00047 20.5 3.1 1 23 1077 1099 1077 1099 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.59	40	5.0	0.0	2	21	361	380	360	383	0.87
2	9	0.0012	0.078	13.5	0.8	1	23	390	413	390	413	0.91
3	9	1.9e-07	1.3e-05	25.4	1.7	1	23	419	442	419	442	0.96
4	9	3.6e-07	2.4e-05	24.5	1.5	1	23	448	470	448	470	0.97
5	9	4.3e-05	0.0029	18.0	3.7	1	23	476	498	476	498	0.97
6	9	0.013	0.87	10.2	1.6	3	21	507	525	505	526	0.93
7	9	7e-09	4.7e-07	29.9	1.3	1	23	1020	1042	1020	1042	0.99
8	9	1.5e-07	1e-05	25.7	1.1	1	23	1048	1071	1048	1071	0.97
9	9	6.9e-06	0.00047	20.5	3.1	1	23	1077	1099	1077	1099	0.98

Sequence Information

Coding Sequence: ATGCGATCCACAGGCTccaacggcgacggcgactacGATCCGAGCGTGGTCCGGCATcatcaccaccaccaccatcacCTGGATCTCAGTGCGGCGCACGGCACGCCAGGATTCGCCGCTCTGCCGCCGGCGCATTTAGCTGCCACTCTGGGCAGCCCAACGGCCTCGAGTCGCCCCGACTCGGATTCTTTTGGTCGCCACCTGCCGCCGACGATATCGCCGCCCTCGCCCACGTCccccggcagcagcagcggcatgcaacgccagcaacagcaacagcaacagcaacagcagtccTCGCAGCGTCACTTGCGTCCCACCGCtgccgcctccgccgccgctgccgctgcctccgCCTCCCTCTCCGCGTCCATTGCGAACGGCACAAGAGCCGGCCTGGAGCATCTGCTGAGCGACGAGCATGCGGAGCGTCTGCTGCTCGACATGGCGCGGCTGCGAGAGCCCGTCTCCAATCTGGACATCCGTGATAACGGCGTCTTCGCCAAGACGTATCTGCCCCGCGGCACCCGCTACGGCCCCTTCCCCATGCGGCTCTGCCAGCAGCCCAGCGAGCGACACCTGGCCTGGGAGGTAATTGCCGGACCGCTGTTCCATGGCTGGCTGGAGCCCTCATCGGACGTGGCCACATGGCTGAAAAAGATACGCGCCGTGCAAGTCGAAGAAATCGAAGAGGCTAATTTGAGGAACTTTATCATCGCCGGCTACTTGTGGTACGAGACGAAGCGGGACGTGAATGCAGGCGCTGAAATTGTGGTCGATGCGCGGCCCAAAACTCCCTACGACATCAGCGACAGTTTCGCGGGCGCTGCGGCGGCGGGCGGCGGGGCAGCGGCGTCGACTGCGGCGGccgcggcggcggcagcagcagcagcagccgtagCAACAgtagccaacaacaacaacaacagcagcaacaacaataacaacaataacaatagcttATTAGCCAGCGATGATCGCAGCGATCGAGATAATGGTTCCCATTATAGCGGCGACGAGTACATCAAGGAGAAGAAGGGCGATAACGATTTCACAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGATGATCATTTAGTTGGTGCCCATCACTTCAAGCGCGGAGAATTCGCCTGCGAGCTTTGTGGCCAACGGTTCTGCCATCGTCCGCTGCTGATCAAACACGGGGCTATCGCTCACAACAACATCCGCAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGAGCTCGCAGTCACCCGTGTCCGGAGTGCGGCAAGACATTCGCCACCTCGTCGGGTCTGAAGCAGCATCAGCACATCCACTCGTCGGTGAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCCTACACCCAGTTCTCCAATCTCTGTCGCCACCGTCGCATGCACGCCGACTGTCGCGTCCAAATCAACTGCAAGAAGTGCAACACCAGCTTCAACTCCGTCACGTCGCTCTCGAAGCACAAGAAGTTCTGCGACACCACCGACAGCTTTCGCAGCCACCATCACTCGCAGAGTCgcctccaccaccaccaccaccaccatcatcaccagcagcagcagcagcagcagcagcagcagcagcaacaacagcagcaacagcagcagcagcgacagcagcagcagcagcaacagacgcagcagctgccaccgTTGATCTTGCCACCGGGCGCCCATCAGCGTCTGGCCGAGTCCAACTCCAATCCGAACAACAGCTCGAGCAGCGAGTCCGTCGGCTCAGCGGCCATGGCCACGCCCCCCAACCACCTGTTCATGATGCGGCCGAGCACCTCGTTCTTCGCCGGCTTCCCGCACTACGGCCTGCCCAACTTCTTCACACCCGGGCTGCAGCAGGCGGGCAACTTCCCGCTGCCGCACATGTTCCCCAACCATCCGCAGCTGGCCGAGATGGGACGCGGCCTCGGGCCGCTCGTCTTTCCCAACGCCGccttccagcagcagctgcaggcggCCATGAACATCAAGTccgagtcggagtcggagctGAAGCGCGAGTCGAGTTCGCCGGAGCAGCAGCGGAAGGCGATCAAGCGCGAGGCGCGGCAcagcgacgaggaggaggaggaggccgaggaggaggagcagccagaggaggaggaggagcagcagacgGCGTACAAGCTGAAAATCAAAAGGGAATCCAGCGCCAAGgcggacgaggaggaggaggaaaaCGATCCCGACAACGATAGAAAATCCATAGACATTGTGAGCACGCCGCCGCCTGCCGAAGGCGACTCCGAGCCCGAAGcggagccggagccggagAAGAGCAGCGCTGAGCTGCCGCTGGATCTGTCCATCAGCCGCAAGCGTCGCAGCTCGGCGCCGCGCTCCATCTCGCTGTCCAGCCGCACGCCCACGCCGGAgctggaggcggaggcggaggggGACGAGCCGCCGCCGTCGAAGCTGGCCAAGCACAACGCCAGCTCGGGCGAATCCTCGTCGACGTCGCGCCTCTCCTACAAGGGCAGCAGCCCGACGCACAGCGCCAGCGCCTCGCCCGCTCCCCACAGCTCGCCCTCGCCCCCCATCAGCACGGGCGGCGAGCTGAGCAGCATGTCGGAGAgcgccgccgtcgtcgcctCGGCCTCGGCGTCGACGTCGgcggccgccgctgccgccgtctCGGCCATGGCCTGTCCGCGGCCGCTGCatccgcagctgctgctcgaggAACTCTATCGCAGCCGCTTCTCCACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCGCCTGTCGCTGGAGCGCACgcgcccagcagcagcgcctCGCGTCATCTGCCGTTTCCGCCCGAGCACAATTTCCGCGAGGCGCTGCGGGCCGCCGGCCTGTCCGCCGCCCGGCCCACCATCGCCGCcagccacaaccacaaccacagtCAGAGCGGAGGACGCTTGAAGGATCGCTACACCTGCAAGTTCTGTGGCAAGGTGTTTCCGCGATCCGCGAACCTGACGCGCCATCTGCGGACGCACACCGGGGAGCAGCCGTACAAGTGCGAGTACTGCGACCGCTCGTTCAGCATCTCGTCGAATCTGCAGCGCCACGTGCGCAACATCCACAACAAGGAGCGGCCGTTTCGCTGCCCCATGTGCGATCGCTGCTTCGGCCAGCAGACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGACGCGGGCGGCTTCGAGTATCACGACTCGCCCAGCTCGAACGAGGCCAAGGATCGCGACGAGGCCTGCTTCGACGACATCCGCTCGTTCATGAAGGGCGTCTACACGCCCACAAGTCTGGGCGGGGCGGACGGGGACACCGAGGAGTATGCGGGCAGCGACGATCAGTTGTCGGTGTCGACGCGGCAGTCCGTCAACTTCGACAAggacaaccacaacaacaacaacaacaacaacactgacaacaacaacagcaacagcagcagcagcagcaacaacaacaacaaccacagcaacaaccacagcaacaacagcaacaacaatgccacagCGCTGAGCGAGACGATCGCTGTGAGCACCTAA
Protein Sequence: MRSTGSNGDGDYDPSVVRHHHHHHHHLDLSAAHGTPGFAALPPAHLAATLGSPTASSRPDSDSFGRHLPPTISPPSPTSPGSSSGMQRQQQQQQQQQQSSQRHLRPTAAASAAAAAASASLSASIANGTRAGLEHLLSDEHAERLLLDMARLREPVSNLDIRDNGVFAKTYLPRGTRYGPFPMRLCQQPSERHLAWEVIAGPLFHGWLEPSSDVATWLKKIRAVQVEEIEEANLRNFIIAGYLWYETKRDVNAGAEIVVDARPKTPYDISDSFAGAAAAGGGAAASTAAAAAAAAAAAAVATVANNNNNSSNNNNNNNNSLLASDDRSDRDNGSHYSGDEYIKEKKGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCGQRFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHRRMHADCRVQINCKKCNTSFNSVTSLSKHKKFCDTTDSFRSHHHSQSRLHHHHHHHHHQQQQQQQQQQQQQQQQQQQQRQQQQQQQTQQLPPLILPPGAHQRLAESNSNPNNSSSSESVGSAAMATPPNHLFMMRPSTSFFAGFPHYGLPNFFTPGLQQAGNFPLPHMFPNHPQLAEMGRGLGPLVFPNAAFQQQLQAAMNIKSESESELKRESSSPEQQRKAIKREARHSDEEEEEAEEEEQPEEEEEQQTAYKLKIKRESSAKADEEEEENDPDNDRKSIDIVSTPPPAEGDSEPEAEPEPEKSSAELPLDLSISRKRRSSAPRSISLSSRTPTPELEAEAEGDEPPPSKLAKHNASSGESSSTSRLSYKGSSPTHSASASPAPHSSPSPPISTGGELSSMSESAAVVASASASTSAAAAAAVSAMACPRPLHPQLLLEELYRSRFSTPPFHFLGQMGGRPGFESPVAGAHAPSSSASRHLPFPPEHNFREALRAAGLSAARPTIAASHNHNHSQSGGRLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCEYCDRSFSISSNLQRHVRNIHNKERPFRCPMCDRCFGQQTNLDRHVKKHEADAGGFEYHDSPSSNEAKDRDEACFDDIRSFMKGVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSVNFDKDNHNNNNNNNTDNNNSNSSSSSNNNNNHSNNHSNNSNNNATALSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00562615;
90% Identity: iTF_00509265; iTF_00520791;
80% Identity: -