Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010018076.1:22822-26760[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.7e-05 0.0077 16.9 0.4 1 23 172 195 172 195 0.96

2 14 0.0015 0.15 12.9 3.1 2 23 244 266 240 266 0.90

3 14 0.0066 0.66 10.9 0.8 1 23 363 386 363 386 0.93

4 14 0.15 15 6.6 3.7 2 23 435 457 434 458 0.95

5 14 0.00059 0.059 14.1 0.4 1 23 528 551 528 551 0.92

6 14 1.7 1.7e+02 3.2 0.1 2 14 570 582 569 594 0.85

7 14 0.00085 0.085 13.7 4.2 2 23 602 624 602 624 0.97

8 14 0.076 7.6 7.5 0.9 1 23 720 743 720 743 0.94

9 14 4.4e-05 0.0044 17.7 0.3 1 23 777 800 777 800 0.93

10 14 0.0037 0.37 11.6 1.5 2 23 850 872 849 872 0.95

11 14 0.016 1.6 9.6 1.8 1 23 971 994 971 994 0.91

12 14 0.0018 0.18 12.6 1.4 1 21 1046 1066 1046 1067 0.95

13 14 3 3e+02 2.5 0.1 3 23 1100 1123 1098 1123 0.80

14 14 3.7 3.7e+02 2.2 0.3 1 11 1143 1153 1143 1167 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.7e-05	0.0077	16.9	0.4	1	23	172	195	172	195	0.96
2	14	0.0015	0.15	12.9	3.1	2	23	244	266	240	266	0.90
3	14	0.0066	0.66	10.9	0.8	1	23	363	386	363	386	0.93
4	14	0.15	15	6.6	3.7	2	23	435	457	434	458	0.95
5	14	0.00059	0.059	14.1	0.4	1	23	528	551	528	551	0.92
6	14	1.7	1.7e+02	3.2	0.1	2	14	570	582	569	594	0.85
7	14	0.00085	0.085	13.7	4.2	2	23	602	624	602	624	0.97
8	14	0.076	7.6	7.5	0.9	1	23	720	743	720	743	0.94
9	14	4.4e-05	0.0044	17.7	0.3	1	23	777	800	777	800	0.93
10	14	0.0037	0.37	11.6	1.5	2	23	850	872	849	872	0.95
11	14	0.016	1.6	9.6	1.8	1	23	971	994	971	994	0.91
12	14	0.0018	0.18	12.6	1.4	1	21	1046	1066	1046	1067	0.95
13	14	3	3e+02	2.5	0.1	3	23	1100	1123	1098	1123	0.80
14	14	3.7	3.7e+02	2.2	0.3	1	11	1143	1153	1143	1167	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCGATGTTCTCATCGGAGTTCGAGGACGGTGAGCCGGAGGGGGGTGGCGAGGGAGAGCTGCTGGAGGGTGGCGAGGATGGGGCGCAGTACGGCAACGGAAATGGGGACCTTCTCGACGATACGGCGATCCTGGAGGCTGGAGATGGTGTTGATGACCTGCTAGATGGGGAGGACGATGAGCGAGAGGAGGACGACGAGGGTGGCATGGAGAAGGTATCGAAGGGACCGGAACCGGACGACGATGCGCTCTTCGACTTCGAGCTGGAGCCGATTGTGAGTATTGGGGAGCCGTCGCCGGCGTCGGTTCTGGCGCCCGCCGGTCCGATGGGCGCCCAAGTGCGCCCAGCTCTGCAGCGTCATTCACTGCCACCCCTGAGTCGGCCGCGGTCCGATACGCGACCGATGGGGTTTCCCGTGCGTCCCACCACCTCACAGATCAATGCCACCGACGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTTGTGTACATCTGCCCAGCCTGCGGAGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAATCAAATCCACAGATACAACACCCTTCGGGGCCTCAACTTTGCGCCGCTGGACAAGCTCTATCAGCGCTGCAAAGAGTGCCACAAGCGCATCGCTATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACGCACCTGCCGTTCCGGTGCACCAAGTGCTACATTTGCAAGCGGGAGTATAAGTACAGACAAGATCTAATGGTGCACCTGCGTATGGTCCACTGCGACGAAGTGGTGGCCATGATGCGGGAAGGTTACAATGCTGCCGGACGCAAAACCCGTGTCCGAGAGTCTCGCACTGAGCAAATGCAGCGCGAGAAGAGTTTCCTAGAGGACGAGGACCTAGATCACATCGAGGTGCGAAACGAGCTGCTCGAACCGGATTTGGATGAGTCTGGCGGCATCATGGAGCATCATGCGTCGCTGCTGGTGGAGGAGACGCCCCATAAGAAGCGACCCGGCGGCGGCAGTGGCGGAGAAGCCGCTGAGCTGTGCGAGGACTACATCCACTACATGTGCCCCGACTGCGGCACCGAGTGCGACACCCACGCCCAGTGGAGCCAGCACATTGAGTTCGTCCACGACTATGTCAGCCGGCGTGGCCTCAACTTTCGGAGCGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTGACACCCAACACCATCAAGTCGCTGCGCGCCCACAAATTCAGTCACTTGTCGCACCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGAGCATCCGAAACTGGTTAGGCATCTGCTGAAAAATCATCACCTGGAGACGCTGATGTCGGAGGACGCTGGCCAGGAGGAGGAGGATGCCCCGCTGGTCGTAGAGGCGGGGAATGAATGCGAAGACAATGGCAATGGCAATGGCGAGGGAAACGGCGCCGCCTTGGACGAGGATTCGCCGTACTTCGAAGACGCCCCCCGACGCGGCGGTCGCATTAGCAGCGACGACATTTTCGAGCCGCACATCGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATAGAGAAGAAGCACTGGCGCACCCACGTGGTCATGGCACACAGCATGAACGACCTGTCCAAGCTGAACTTCGAGATGATCAACGAGCGGCAGCTGAAGTGCACGGAGTGCGACAAGATCATCACGAACGCCTATGGCATACAGAATGCCCAGCAGCACAGGATCACTCATCTGCCATTCAAGGCGTACGCCAGATGCCGCAAGTGCCATAAGTCTTACACTGACCGAAAGGGTCTCGTCAAGCATCTGTCTACCTATCACCGCATCGGCTGTGAACCCAGGAAGTCTGGCGGGGGTGCAGCAGCAGCAGCACCTTTGCCCATGCCAACGGCCCCCAAGCAGCCCCGCAAGCAGATCGTCACAGTGGCCAACGAGACGTACGAGATTATCTACCTGGACGATGTGGAGCAGAGCAGCCTGGACGAGGAGAACGACTTTGGGGAGCAGATGCTCGCCGACGAGGACGATTACCCGGTTGTTCAGCCCCCGCAACAGCGTCAGAGGCCGCCTGCACCACGACCCTTGCCGCAGAACTCTCAGCAACGCTACAAGTGTGTCCACTGCAGCACCCTCTTCCCCACCCAGATGGCCGTGCGGCTGCACATCAGCGAGAAGCATTGCCGGAAGCCGCATCAGACGGGCCGAAGGCATCGCCATTTGATCGCGCATTCCGGTGGGGCAGACTCGGGCCTCACCACCGTGGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAACTTCGACAAGCGCAACTACCTGAACATGCGGCAGTTGGACAAGTACCGCTACCAGTGCACGCAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTGCAGGACCACCACTTCCGTCACCTGCCCTACCGCCTGTATCTCAAGTGCTTGGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCAGCCCATCTCAGGGCTCGCCACAACATCTGCGACAAAGAGCCGACCCTGGTGGTCACCAAGCCGATTAAAACCTACAGTCGGTTCAAGGATGCGGACAAAGAGAAGATCTCGCTACCCACTCCGACGCCGGCAGCATTATCTCCCCCCGGCTGCTCCTCCTCCTCTTCCTACTCAACAGCTGTTGTTGCTGCCGGGCCCGCGGTCAGTCGAACTCTTAAGCCCCAACCCGGTGACCTGCCCACGCGACCCGCTGGCCTAAACACCCTGGAGGACAGCATCTCGTACCACAATGCCGTAGACATGGACTTCATCACCTACTTCTGCCCGAAGTGCAACCAGAACTTCGACTCGCATGCCTTCTGGCGGAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGTCTGAACTTCCGGCAGATCGACAACCACCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTGACCCACACCAAGGGCGCCATAGGGCAGCTGCAGTCGCACAAGTTCCGGCACCTTCCCCACCGCTCCTTCAAGTGTCTGACCTGCGACGCCTCCTTCGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACCAACCGGTGTGACAATCGTCCGCAACGCGAGTTGGACGACGAAGAGCCCAGCCCGGAGGACTCTCAGCTGACCACCATTTACCACCTGGCGTGTCCGCAGTGCGGCGATGACTTCAACACCGCCAGTCGGAAGCAGTGGCGCGATCACATCAACGTCTTTCACGGCCTCACCGCGCTCGAACTGCTGCACATGAAGAAGGTGGATGGCGCGGAGGATCTCTATCGTTGCCAGGACTGCAACGAGGAGCTGCAGACGAACCGGCAGTGGGTGCTGCAATACCACCGCTTTCAGCATCTGCCTCAGCCGGCCTACATCCGCTGCCAGCTGTGCGAGCAGAACGGTGAGCGAGATGCGGCCGTGGGATCCGGGATGCATAGTCTGCGCGAGCTGCAGCAGCATCTCCGCAAGCATCATCCCACAACGGTGGGCGAGAACGAGCTGCAGATGCTGCGCGAACAGATTGCCCTGGAGGAGAAGGAGCAGGAACAGGCAGTGGGCCTGGCTGCGGATGAAGAGATGGGCCAGGACTCCGGACCCTACATGCCGCTTCCGCCCCATTTACTGGACGACGGAGACGTCGAGTTCGAGGACCAGTATCTGCTGGGGTAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEPEGGGEGELLEGGEDGAQYGNGNGDLLDDTAILEAGDGVDDLLDGEDDEREEDDEGGMEKVSKGPEPDDDALFDFELEPIVSIGEPSPASVLAPAGPMGAQVRPALQRHSLPPLSRPRSDTRPMGFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMQREKSFLEDEDLDHIEVRNELLEPDLDESGGIMEHHASLLVEETPHKKRPGGGSGGEAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTEHPKLVRHLLKNHHLETLMSEDAGQEEEDAPLVVEAGNECEDNGNGNGEGNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLSTYHRIGCEPRKSGGGAAAAAPLPMPTAPKQPRKQIVTVANETYEIIYLDDVEQSSLDEENDFGEQMLADEDDYPVVQPPQQRQRPPAPRPLPQNSQQRYKCVHCSTLFPTQMAVRLHISEKHCRKPHQTGRRHRHLIAHSGGADSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNICDKEPTLVVTKPIKTYSRFKDADKEKISLPTPTPAALSPPGCSSSSSYSTAVVAAGPAVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSPEDSQLTTIYHLACPQCGDDFNTASRKQWRDHINVFHGLTALELLHMKKVDGAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQNGERDAAVGSGMHSLRELQQHLRKHHPTTVGENELQMLREQIALEEKEQEQAVGLAADEEMGQDSGPYMPLPPHLLDDGDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492530;
90% Identity: iTF_00492530;
80% Identity: -