Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010020074.1:29571-33206[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.011 1.1 10.2 0.0 3 23 217 238 216 238 0.93

2 8 9.6 9.6e+02 0.9 1.2 2 21 827 848 827 850 0.87

3 8 1.4e-06 0.00014 22.4 2.8 1 23 920 942 920 942 0.98

4 8 0.00024 0.024 15.4 2.2 1 21 976 996 976 997 0.94

5 8 1.3e-05 0.0013 19.3 0.4 2 23 1004 1025 1003 1025 0.97

6 8 0.017 1.7 9.6 3.9 1 23 1031 1053 1031 1053 0.98

7 8 0.0085 0.85 10.5 2.0 1 23 1059 1082 1059 1082 0.97

8 8 0.0011 0.11 13.4 0.5 1 23 1092 1114 1092 1114 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.011	1.1	10.2	0.0	3	23	217	238	216	238	0.93
2	8	9.6	9.6e+02	0.9	1.2	2	21	827	848	827	850	0.87
3	8	1.4e-06	0.00014	22.4	2.8	1	23	920	942	920	942	0.98
4	8	0.00024	0.024	15.4	2.2	1	21	976	996	976	997	0.94
5	8	1.3e-05	0.0013	19.3	0.4	2	23	1004	1025	1003	1025	0.97
6	8	0.017	1.7	9.6	3.9	1	23	1031	1053	1031	1053	0.98
7	8	0.0085	0.85	10.5	2.0	1	23	1059	1082	1059	1082	0.97
8	8	0.0011	0.11	13.4	0.5	1	23	1092	1114	1092	1114	0.98

Sequence Information

Coding Sequence: ATGAGCGATGCGGCCTACCCAGGCTTTTTCGGCGGCAGTAGCAGCAGCCAGCTGCACTTGCTCTCGCTGTCGCACCCCCCGCACCCGCCGCACCAGCACCATTACCAGCTGCACCCGGACCTTTCGCTCTCCACGCCGGTTCACGCCCAGGAGCACGACTCCACGATCTTCAACGGCTTCTTCGACGACGAGCTGGGCATCGTAGGGAACGCTTCCGCCTCCTGTGCGGCACCTGGGAACACAGCCGCTACAGCCGTCTGGCTGCCCGATGGAGACGCAACGGCAGCGCCGCCCCCACCACCGACAGAGGGCATTCCCTTTGTCCAGATCCACACGACGGATCTGCAGCAGCAGCCGGAGAAGAGCTACCGCAACGGGTTTCGCCGGCGCACCGCCGAGATCAAGTCGGAGGCGGAGCTTATCAAGTCGGAGCTGGCGGAGGCCGCCGCCAAGGAGCGTCTGAATGCCACGCCCACGCCGCCTACCCGCAACTCCAGCTGTCAGAGTGTGGAGGGCAAGGCTAATGGCTCTGGCCCGCTTCTAATCCTTCGCTGCCCCAACTGTCCGTTCCTCAGTCTTTGTCAAGCGCGCTTGCAGCAGCACCTGCAGCTGGCTAGCTGTTATTCATTGAGCGAGCAGAGGAGACCGTGTCCGGGCTGCTCTAACGTATTCTACAGCAGCGATGCTCTTAGCCTGCACCTGAGCCTGGATCACCAAATGGAGGACGACGAGATACCTGCGCTGCTCAGCGAGAAGCCCAGCGAAGTGCATGCCAAGAAGCAGGCGCAGAACCCAAGCCAAAACCAGCCCAAGAGCCGCATCTTCATCAAGAGCGTGGACTGCCTACGGGAGCCGCAGCAGCAACAGGTGAACGTGAACTCCATGCCGGATTTCCCACCACTGATGTCAGACAGCGGCTGCACTGGCAACATCCTCGACCTGCTGGATGACGTGGCGGTGGGTGCTTCGCCCAGCGAACAGACCATGCCGCCGGCACCTGAGAGTGCGTCAGCACCGCCGCCGAAACCCAGTCAAAAAATATCTATTAAAAGCGTCGACGTGCTCAGGGAGCCAGCGCTGCTGCCCTTCGACTTCCACTTGTCAAATCAGCCGCTTATCACGGCCAACAGCCTGCTTGACGTCCCAGTCGTAGGTGTGGTGCCCGAGAAGCCGCGGCATCCAAAGATTTACATCCGCAACGTTGACATCCTCAAGGAGCCAATGGTTTTGCCATCCGCCCTGCCCGGAATGGGTTTCAACGGCAGTCTTCCGGCTGCAGTGACTGCGGGGAATCCGGGAACAGTAGCAGGCGACGGAGGAGGAGGAGGTGACGTCTTCCAAGCAGATCCCCTGCTCACGCCCACTTGCCCGCTGCCGGGATTTGAGCCTAGCCTCGCGCCCTTGGCCCAAATGTGCTCCGAGGTCTTTCCCTTTGACTCGGTACTGAGTGGGAATGGAGGAGCGGTTTCCGGACTAGACAACACTCGATTCAGCGCTCTGGACCTTGACTTTGGCGTGGATTTTGTTTCGGACGAGACTCCGCCGCCTCCTCCGCTACCGCTACCTCTCAATGGCCAGATGGAGCCTCCAATGCCTAGCATTGGGCCGCAGCCCGTTCAGTTGGAGCACTACCTGGCTCCCACGGCTGCTGCTCCAATCACGACCAAGCAGAAGATCTTCATCAAGAACGTAGACATCCTCAAGGCCCCGCAGAGAGGAACGCTGCATCTGCGCACCGTGGACGAGCTGAACCTGATGAACCGCACCGAGGTCGAGCACCTGATAGTGCCCAATCTGGAGCCTATGGCAGCCATGTCGATGATGGAGCTGCCGGCCGTGGAGCCGCATCAACAACAGCCGCTGGAGCTGGATCCCCAGTCGCTGGGCGACTTTCAGCCATCCATTAGTGGGAGTTGGCCCAGCGAGGATGGCTACGACCTGGCCGAGGACCTCGAGGGCTGGCCCTGGATGGAAGAACCTGTGCCAGATGCCGGAGTTTCTTCACTCGCCACTCCTAATGAGGTGGCAGGTGGAGAAGGTGTGGACGCACCGCCACTCGAGGGCTTCTCACACGCTGCCGAGGATCTACTGGTCAAGGACTTTCCGCAGCTGTACGTCTCGCCTCCGGAGGAGTTTCAAGGCACAGGGGCTGAAGTAGAAGCTGGAGGAGGTGCAGTTGTGACACCTCTGGTGCCCGTTACAACATCTGGAGGGACGCCTGCGACGGCTCAAAGCGCAACTCTGAGCGGCTTGCCGGTTCCACCGCTCGTGCCTTTGGCGGCGGAAGCCACACCAACGCCGGCGGAAAAGCCCGCCCGCATATATGTGGCCAGCAATCTTCTGCCCGCTGCTGTAGAGCCACCAATGCCCGGAGGTACTTCTGTCCGCGGGCGACCCTACGGAGCCAAGCACTCAGGCGGCAGCGCAGCTTCAAAGAGGAGGCCACCGCAGGGCTCCAGCCAGGTGTCCGAGGGCGGCAAGTGCCAGGTGGAGGGCTGCATGTTCAGGTTCAAGTCGCCCGCCACCCTGGAGTATCACGGAAGGTGCCACAACGGGCTGCCCAACTCCAGCCAGCCGATGGTCTGCCCGGAGTGTAAGTCGAGCGACTTCAGCAACTGGAACTGCCTGCACACGCACCTGTGGCGCACCCACCAGATCGACATGGAGCTGTACTGCTGCAAGCTGTGCAGCTTCAAGACGCCCATCTACTCGCGCCTGGTTAACACGCACGCCAAGATCCACTCGGAGGAGCGGAACTACAAGTGCGAGCAGTGCGGCAAGGGCTTCAAGAACACCAAACAGCTGAAGAACCACCGACGGCTGCATCGCACCCAGGGGCTGGGTATGGGCAAACATGGCCAGGCAGATCAGGACCAGCAGCAGCAGGGGGGCTCCCTCCCCGGTACAGAGGCCGCCGTGATGATGCATCGCTGCGAGGATTGTGGTGCGGCGTTCAAGCAGCGGAAGACCCTGAGGGAGCACCTGTGCAAGGAGCGCAATGAGCAACTCGAGTGTCCTGAGTGCCAGCGCCTCTTTGGTTCAAAGAGCAGCCTACGACTGCACCTACGGACGCATCAGGAGCGAAAGCGGTTCCGCTGCGACACCTGTGACCACGAGACGAGCGATCACAATGCATTTCGGCGGCATCTGGGTACGCACAAGGAGAACAAGCGCTACTACTGTCCCCACTGCGACTTCAAAGCCATCCAGAGCACCGCCTTTCGGATACACCTCCAGAAGCGCCATCCCGAGCAAGAGCTGTCCTCGATCATTTACAAGTGCGACCAGTGCAGCTTCACGAGCATCAATCAGGGCCTGCTGCAGGTTCACCAGGCCAAGCACGAAGCATCAGCAGCAGCTCCAGCTCAAGCCCCCGCCACAAACTCCTCACAGATCAAGGTAAAAAGCCAGGTGGTGCGCGCGCATTCCAGTACAAAGGTGGACCGGCAGGCTGCTTCCTAA
Protein Sequence: MSDAAYPGFFGGSSSSQLHLLSLSHPPHPPHQHHYQLHPDLSLSTPVHAQEHDSTIFNGFFDDELGIVGNASASCAAPGNTAATAVWLPDGDATAAPPPPPTEGIPFVQIHTTDLQQQPEKSYRNGFRRRTAEIKSEAELIKSELAEAAAKERLNATPTPPTRNSSCQSVEGKANGSGPLLILRCPNCPFLSLCQARLQQHLQLASCYSLSEQRRPCPGCSNVFYSSDALSLHLSLDHQMEDDEIPALLSEKPSEVHAKKQAQNPSQNQPKSRIFIKSVDCLREPQQQQVNVNSMPDFPPLMSDSGCTGNILDLLDDVAVGASPSEQTMPPAPESASAPPPKPSQKISIKSVDVLREPALLPFDFHLSNQPLITANSLLDVPVVGVVPEKPRHPKIYIRNVDILKEPMVLPSALPGMGFNGSLPAAVTAGNPGTVAGDGGGGGDVFQADPLLTPTCPLPGFEPSLAPLAQMCSEVFPFDSVLSGNGGAVSGLDNTRFSALDLDFGVDFVSDETPPPPPLPLPLNGQMEPPMPSIGPQPVQLEHYLAPTAAAPITTKQKIFIKNVDILKAPQRGTLHLRTVDELNLMNRTEVEHLIVPNLEPMAAMSMMELPAVEPHQQQPLELDPQSLGDFQPSISGSWPSEDGYDLAEDLEGWPWMEEPVPDAGVSSLATPNEVAGGEGVDAPPLEGFSHAAEDLLVKDFPQLYVSPPEEFQGTGAEVEAGGGAVVTPLVPVTTSGGTPATAQSATLSGLPVPPLVPLAAEATPTPAEKPARIYVASNLLPAAVEPPMPGGTSVRGRPYGAKHSGGSAASKRRPPQGSSQVSEGGKCQVEGCMFRFKSPATLEYHGRCHNGLPNSSQPMVCPECKSSDFSNWNCLHTHLWRTHQIDMELYCCKLCSFKTPIYSRLVNTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMGKHGQADQDQQQQGGSLPGTEAAVMMHRCEDCGAAFKQRKTLREHLCKERNEQLECPECQRLFGSKSSLRLHLRTHQERKRFRCDTCDHETSDHNAFRRHLGTHKENKRYYCPHCDFKAIQSTAFRIHLQKRHPEQELSSIIYKCDQCSFTSINQGLLQVHQAKHEASAAAPAQAPATNSSQIKVKSQVVRAHSSTKVDRQAAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00485428;
90% Identity: iTF_00562018;
80% Identity: -