Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010016526.1:6300-8434[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.6e-06 0.00026 21.6 0.5 1 23 403 425 403 425 0.98

2 7 7.1e-05 0.0071 17.0 0.4 1 23 431 454 431 454 0.98

3 7 0.076 7.6 7.5 0.8 1 23 460 483 460 483 0.89

4 7 7.8e-05 0.0078 16.9 2.1 1 23 506 528 506 528 0.98

5 7 5.7e-07 5.7e-05 23.6 0.8 1 23 534 556 534 556 0.99

6 7 0.0012 0.12 13.2 0.3 2 23 563 584 562 584 0.96

7 7 0.00023 0.023 15.4 2.2 1 22 590 611 590 614 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.6e-06	0.00026	21.6	0.5	1	23	403	425	403	425	0.98
2	7	7.1e-05	0.0071	17.0	0.4	1	23	431	454	431	454	0.98
3	7	0.076	7.6	7.5	0.8	1	23	460	483	460	483	0.89
4	7	7.8e-05	0.0078	16.9	2.1	1	23	506	528	506	528	0.98
5	7	5.7e-07	5.7e-05	23.6	0.8	1	23	534	556	534	556	0.99
6	7	0.0012	0.12	13.2	0.3	2	23	563	584	562	584	0.96
7	7	0.00023	0.023	15.4	2.2	1	22	590	611	590	614	0.91

Sequence Information

Coding Sequence: ATGAGATGTGCCGTGCCCAATTGTAGGAATGCTTCCATACGCAGATCCAATAGGGACGCGGATCAGCAGAAGCCGGTTTCCTTCTTCCAGTTCCCCAAATCCCCGGAGTTATTCAACAGATGGCTGTCGTTCTGCCGCGGCTCAGAGAATGGCCTAAAAGTAAAGAATCCGTGCATCTGCATCGAGCACTTCCGAGACGAGGACATAGAGGGGTCCATAAAATTCGAAATGGGACTTGCTAAGAAGAGAACGTTACGCCCGGGTGCGGTTCCCTGCATTAACAAGAGCCAGGAAAGCCCCTCGGAAAAGGCACGCTTAGAGCGCTCCAAGCGACGCAGTAACCATAAACTGGTGGCCGAACTACTCTTAGAGGATGAAGTGAGGTCTAATGCTACCGCAGAGGTGGTTCCCACGCCCAATTATGTCCGGTTAAACACGGGAATTGCTTCGGCTCCTCCATTCGTTAGTCCCAGGCCGGCAGAAGATGACTTAGCTTCTGTAATCGTGGAATATGATCCTGATCCCCTTGTTGCCGCAGCAGAGGCAGAAACGAGGGACAAGTGCCGTATCTGCTACAAGGATTTTATTGTCGATGAAAATGCCAAATATCTCTTCGACCCGGAAAACAGTGTGCTAATTTTCCACATTGAAGTCATTAGCGGTGTTTGGATACAAAATATCGAAGACGAACCGCAGCTCATGTGCCCCGCATGTCAGCTGTCCCTCCAGATGGCGATTGAGTTCCGGGAGATGTGCATAGGCGTTGAGCTGAAGCTCACCCAGCCCAAGGTTGAAATTGATGAAGAACCCGATCTGGAGTCGGGCCAGGAGGAAGCATTAGAACTTGATATTTATTCGGACTCTGAATATTCCTATCTCGACGAATATCCGCCGGACGAGTCTGTGGTAAACGAAGCCCTCCCCAATACTGACCTAACACTAGATTCGATGGCAGAAGCTCCCGAGCTGGGTTCATCCGATCCCCTCAGTGTGGCCCCTGGAGCCACGATTGTCAAGGATTTAATCCGCCAGTACACGGGAAAGTCCACAACCAAAATAAAAAAGGAGGCTACTGTGGCAAAGGCGACCGAACCCAAGTCTACTGCTGTGGATTGCGAAGAAAACCCGAAGAGAAACGCTAACCCTAGAACCAAAGAAGAGAGAAACTTTATCCGTCGTGCTCAGATTCGAGCCAGGCCAACGAACTTCGTGTGCGATCAGTGCGGCCAGGCCTTCCGCATGGCTCACAATCTGCAAATTCACATCCTCCGGCACACCCGGACCAAGAACTACCAGTGCACCGAATGCCCCATGACTTTCTACGACGCCTACATGCGCAACATCCACATCCGAATCAAGCATCGCGGAGAGACGCCATTTAACTGCCGACACTGCAAGGCCACGTTCGCCTATGCGGGAGCTCGTCAGAAACACGAAAGCGGGGTCCATGGAGCACCGCCCCGCCGGATCGTGAAACGAATCAATCCCCAGCCCATGCCCCGCTCCAAAACGCGCTATCATTGTGAGCTCTGCGATAAACACTACGCGTCCAAGTACGCCCTGGCCTGGCACGTCAAGTCGCACACTGATGCGGGAGCCTACAAGTGCCAGTTGTGCGACAAGAGCTACTCAGACCCGGCCAAGCTCAAGCGCCACGAACTTACCCACGACGACAAGAGGCCGCTTCAGTGTGAGGTGTGCCTGAAGGGATTCTACCAACAAACGAAGCTCAGGGAGCACGAGCTCATCCACACCGGCGAGCGTCCCTATCGGTGCGAGATCTGCGATGTCCACTTCCGCTACAAGTACAACATGAAGGTACATGCCAACAGCAAAATGCACCAGGAGAACCTGTCGAAAGCGCAGTCCAATCAAATTGTAGAAATTTAA
Protein Sequence: MRCAVPNCRNASIRRSNRDADQQKPVSFFQFPKSPELFNRWLSFCRGSENGLKVKNPCICIEHFRDEDIEGSIKFEMGLAKKRTLRPGAVPCINKSQESPSEKARLERSKRRSNHKLVAELLLEDEVRSNATAEVVPTPNYVRLNTGIASAPPFVSPRPAEDDLASVIVEYDPDPLVAAAEAETRDKCRICYKDFIVDENAKYLFDPENSVLIFHIEVISGVWIQNIEDEPQLMCPACQLSLQMAIEFREMCIGVELKLTQPKVEIDEEPDLESGQEEALELDIYSDSEYSYLDEYPPDESVVNEALPNTDLTLDSMAEAPELGSSDPLSVAPGATIVKDLIRQYTGKSTTKIKKEATVAKATEPKSTAVDCEENPKRNANPRTKEERNFIRRAQIRARPTNFVCDQCGQAFRMAHNLQIHILRHTRTKNYQCTECPMTFYDAYMRNIHIRIKHRGETPFNCRHCKATFAYAGARQKHESGVHGAPPRRIVKRINPQPMPRSKTRYHCELCDKHYASKYALAWHVKSHTDAGAYKCQLCDKSYSDPAKLKRHELTHDDKRPLQCEVCLKGFYQQTKLREHELIHTGERPYRCEICDVHFRYKYNMKVHANSKMHQENLSKAQSNQIVEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00524598;
90% Identity: iTF_00524598;
80% Identity: iTF_00613543;