Basic Information

Insect: Drosophila tsacasi
Gene Symbol: Znf516
Assembly: GCA_018904565.1
Location: JAEIHY010014283.1:833-2455[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.6e-05 0.0016 19.1 0.2 1 23 208 231 208 231 0.90

2 8 4.2e-07 4.2e-05 24.1 2.5 2 23 253 275 252 275 0.94

3 8 9.8e-05 0.0098 16.6 0.1 3 23 297 316 296 316 0.97

4 8 1.8e-06 0.00018 22.1 0.7 1 23 322 344 322 344 0.99

5 8 1.9e-06 0.00019 22.0 1.8 2 23 351 372 350 372 0.97

6 8 1.2e-06 0.00012 22.6 0.4 1 23 378 400 378 400 0.99

7 8 2.1 2.1e+02 3.0 1.0 1 21 406 426 406 430 0.85

8 8 0.0036 0.36 11.7 0.1 1 22 495 516 495 519 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.6e-05	0.0016	19.1	0.2	1	23	208	231	208	231	0.90
2	8	4.2e-07	4.2e-05	24.1	2.5	2	23	253	275	252	275	0.94
3	8	9.8e-05	0.0098	16.6	0.1	3	23	297	316	296	316	0.97
4	8	1.8e-06	0.00018	22.1	0.7	1	23	322	344	322	344	0.99
5	8	1.9e-06	0.00019	22.0	1.8	2	23	351	372	350	372	0.97
6	8	1.2e-06	0.00012	22.6	0.4	1	23	378	400	378	400	0.99
7	8	2.1	2.1e+02	3.0	1.0	1	21	406	426	406	430	0.85
8	8	0.0036	0.36	11.7	0.1	1	22	495	516	495	519	0.91

Sequence Information

Coding Sequence: ATGGACTCCGCCGGCATAAACCATAATATTAAGACCTGTCGCGTCTGTCTGGAGGCAGACGAGGCCAACACAAGCCTGTGCCTGTTCGACGAAATCGAGTACAACGAGCTGAGCGTGGAGCTGGGGCAGCTTTTGCAGTTTGTGTCCAAAGTGAAGATGGCCGGGGATCCGAATCTCCCATCCCAGATCTGCCAGACCTGCACCCAGCGGCTAATCAGCGCCTACGAGTTCATCCTGGAAGTGGAAAGCGCCGAGAAGAAGCTGCAGAGTCTGTGCCTGCAACAGGCGGAATCGGCAGCGACCAAGCAGGACGAGTGCGATGTGGAGGTGCTGGAGCTGATTAACCAGGAGGAAGTAGTTGATGTGGACGACTTCCTGCCTGATGGTTACGAGGAGCAGCAGGCAACCCTGGGGGCGGTGCAGGAGGCTCCAAAATCTGATGTGGAGGATGACCAGCTGTTCGCCGCAGATGATCCAGAAATAATCATTAAAGAGGACGAAGACGACGCTGAGGAGGTTTGTAGGCTAGAAGTTCCGCCAAATGAAGATGAGATTACTCTCCCGCAACAATGTGGCTCCTCCCGGCTGGGCAGTCGTCTGACCCACTCGAATAACTTCACGTACAAGTGTGCCATTTGTCCACGAGTCTTCGCCAAGAGCGAGTCTCTCAAACGACACTTTGACCTGGCCCACAGAAAGACGGCGGACATGGCTGCCCAGGAGTTGGCCAACGAGAGCAGTGGCACCGGCCTGCTGACCTGCGAGCACTGTCCGCGCACGTTCAAGCGCCAGGACACGCTCCGGCGGCATATGCTGGCCTTCCACCCGGACGCACCGCTGGCTGCAAGGGATCACTCGCCCCGTAAACGTGTTGCCAAGCGTCGAGACTGTCCCTATTGCGGCCTAAGCTTTCCCACCTCCAGCCTCACCATCCACATCCGCCGCCACACCGGTGACAATCCGTACAAATGCACCCTGTGCGAGAAGGCCTACCCCCGCAGCCAGGATCTCACCCTGCACATGAGGCAGCACACGGGCGAGCGGCCCAGCCAGTGCAAGATCTGTTCTAAGAAGTTCATCTCTCAAAACAAACTGGCGCGCCACATGCGTCTTCACACGGGCCAGCGGCCATATGTCTGCGGCACATGTAATAAGGGCTTCGTGCAATCCAACGACCTCAAGATCCACTTGCGACGCCACACTGGTGAGCGGCCGTACCACTGCGGAGTGTGCGGCGACAGCTTTGTGTGCGGCTCCCTGCTGAATATCCACCGCAACCAGATGGGTCATCACGAAGTTAAGCACAGGGGCGACGGCGCAGAAGACTCCGTCTCGGAGGACGATCCATATGTTAATGCCCGGGTGAAAGGGCGACGGGCAGAGGACATAGAACGGTTGCGCCTGCTGAGGGCTCCCGAGGATCGATTCGAACAGCCACTGGAGGTTTCTCAACAGAAGCAGCAGTCGCCACCAATTCTCTCCTACAAATGCGGAGTCTGTGAGATGAATTTCAAAAGCGGTGCCCTGCTGACCATCCATCGCAATAACATGGGTCATTACGAGCTGGGAAAGGTGGACTACGGCGATCCCTTTGGGCAGAAGCAGAAAAGACTTAAATATTAA
Protein Sequence: MDSAGINHNIKTCRVCLEADEANTSLCLFDEIEYNELSVELGQLLQFVSKVKMAGDPNLPSQICQTCTQRLISAYEFILEVESAEKKLQSLCLQQAESAATKQDECDVEVLELINQEEVVDVDDFLPDGYEEQQATLGAVQEAPKSDVEDDQLFAADDPEIIIKEDEDDAEEVCRLEVPPNEDEITLPQQCGSSRLGSRLTHSNNFTYKCAICPRVFAKSESLKRHFDLAHRKTADMAAQELANESSGTGLLTCEHCPRTFKRQDTLRRHMLAFHPDAPLAARDHSPRKRVAKRRDCPYCGLSFPTSSLTIHIRRHTGDNPYKCTLCEKAYPRSQDLTLHMRQHTGERPSQCKICSKKFISQNKLARHMRLHTGQRPYVCGTCNKGFVQSNDLKIHLRRHTGERPYHCGVCGDSFVCGSLLNIHRNQMGHHEVKHRGDGAEDSVSEDDPYVNARVKGRRAEDIERLRLLRAPEDRFEQPLEVSQQKQQSPPILSYKCGVCEMNFKSGALLTIHRNNMGHYELGKVDYGDPFGQKQKRLKY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490224;
90% Identity: iTF_00485300;
80% Identity: -