Basic Information

Insect: Drosophila tsacasi
Gene Symbol: zfh1
Assembly: GCA_018904565.1
Location: JAEIHY010016964.1:1-4237[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.4e-05 0.0024 18.5 1.0 1 23 153 175 153 175 0.97

2 14 0.00074 0.074 13.8 1.2 3 23 183 203 181 203 0.94

3 14 0.00024 0.024 15.4 0.2 1 23 367 389 367 389 0.98

4 14 0.00021 0.021 15.6 0.6 1 23 395 417 395 417 0.98

5 14 1.3e-05 0.0013 19.4 2.3 1 23 449 471 449 471 0.97

6 14 0.00046 0.046 14.5 1.4 1 23 506 528 506 528 0.94

7 14 0.13 13 6.7 1.4 1 23 534 557 534 557 0.96

8 14 0.024 2.4 9.1 0.4 3 19 566 582 565 583 0.95

9 14 0.00014 0.014 16.1 5.6 1 23 592 614 592 614 0.97

10 14 0.042 4.2 8.3 0.4 2 23 620 641 619 641 0.96

11 14 8.2e-06 0.00082 20.0 1.0 1 23 650 672 650 672 0.98

12 14 0.00093 0.093 13.5 0.1 3 23 680 700 678 700 0.97

13 14 5e-05 0.005 17.5 0.5 1 23 706 728 706 729 0.95

14 14 0.14 14 6.7 0.1 1 23 739 761 739 761 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.4e-05	0.0024	18.5	1.0	1	23	153	175	153	175	0.97
2	14	0.00074	0.074	13.8	1.2	3	23	183	203	181	203	0.94
3	14	0.00024	0.024	15.4	0.2	1	23	367	389	367	389	0.98
4	14	0.00021	0.021	15.6	0.6	1	23	395	417	395	417	0.98
5	14	1.3e-05	0.0013	19.4	2.3	1	23	449	471	449	471	0.97
6	14	0.00046	0.046	14.5	1.4	1	23	506	528	506	528	0.94
7	14	0.13	13	6.7	1.4	1	23	534	557	534	557	0.96
8	14	0.024	2.4	9.1	0.4	3	19	566	582	565	583	0.95
9	14	0.00014	0.014	16.1	5.6	1	23	592	614	592	614	0.97
10	14	0.042	4.2	8.3	0.4	2	23	620	641	619	641	0.96
11	14	8.2e-06	0.00082	20.0	1.0	1	23	650	672	650	672	0.98
12	14	0.00093	0.093	13.5	0.1	3	23	680	700	678	700	0.97
13	14	5e-05	0.005	17.5	0.5	1	23	706	728	706	729	0.95
14	14	0.14	14	6.7	0.1	1	23	739	761	739	761	0.96

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACGGCACCACCCCGCTGCAGGCGACTCTTCCGAGACGGACCTTCTGGAGCAAGAAGACGCCGACGGCGATGGTATGGTGAGCGGAGGGGACGGCGACCCAGATGGGGATGGGGATGCGGATGCTGACTTGGACCATATGGCTGCCGAGAACCTCATCTTTATGGCGCGCGACGGTCAGCTGGGAGAGATTATCGCCGCCAGTGAGGGAGCTGTCCTGGTCACCGCCGATGGCACGACGGTGGCTTATGCGGAATCCTTTGACGACGATGCCCAGGTGGTGACCGAGGAGGTCATCACCGACGACTGGGTGGAGCACCAAGGAGCCGAGCGCGTGGAAATCGCCGCTGAGCAGATAGCTGGCATCAGCAGTTCGCAGGAACTGTTGGACATGGAGCAGGATGAGTACACGGCTTTGCGTCCCTACCCCTGCGACTTTTGCAGCCGGCGCTTTCGGAAGAAGGCCAGCTTGAACAACCACATGCTGGCACACCAGAACGACCGGCCTCATCTCTGCAAGCTGTGCGGAGCGCGCTTCTCACGCCGGGCCGAGCTCATTAGCCACTTCAAGGCCCACGCCGAAGCCCAGGATGCTGCGGATGCCGAGGCAGCCGCCGCCGCTGCCGTTCCGGTCTCTTCCATAAAATTCGAGCATCAGGGCCACAGGCAGATGGATGATCACTACTACGAGCAGGAGTGGCCGCTGTATCAACAGCAACAGCAGCACGAGCAGGAGCAGGAACAGGAGCAAGTGCAACATGAGCAAATGCTGCAACAGGAACAACAGCAACTAGTTTGCAACAGCGAGGTCCAGTTTGTGGCCAGTTACACAGCAACGGTAGCTCCTCCGCCTGCTCCGTCGCGTGGAAGGATAAGCAGGCTGAAGCCCAAGGAGGAAAGCAGCCAGTTCATCGTAATTACCGATAAGTCGACGTCCAGCGAGTTGCAGGACTACATGGCCAGTGAGCCGGTGCCTCAGCCTATGGTGCCCACGTCGCAGCCCATGGCCATTGATCCGCCGCCTGCGCCTGCGCCAAATTTCCCTGTGCTAGACGACAGCAAACCCTTCGTGTGTCAACAATGCGGATTGGCTTTTGCACGGGAAAAGGCTCTAGTCTCGCACACAAAGAACCATCGCGTGGACTCTCCTTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGATGCATCAGTTTGAGGAGAGCAACTCTGAGTATGATCCCGCCTCTGGCGATGATAGCGCCAGCGAAACATCGGAGCCGGAGGAGCAGCTCTACGGGGAGTTCTACTGCAACGAATGCGGCATCTCCTTTCACCGCCAGGATCTACTGCGTCGCCACGCCAAGCAGCATTTCAAGCAGCAGGATCATAATTCAACGGTGGCGGCAGGAGACGGAAGCTCCTCGGACATCATAGCTAACGGGGATCAGGCCAAAGATGGTAACGGGGGCGGCCACTGTTGTCAAACGTGCGGCAAATCATTTCCCAGTGCCTCGGAGATGCTTTCCCATGCCGAAATTCATGCGAGGTTTCCGCCTTTCAAGTGCGTCCTTTGCGGCGTAAGTTTCTACGAGGAGCAGGTCATCAAGCGGCATCTGCACACTCGCCATCCCAACGAACTGAAGGCCAACTCCTGCGTGCTGTGTGGTAAGGAGTGTCGCGATCGCAAGGCACTGATCAAGCACGCCTGGGATCACTCCCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCATAATAAAGCGCGACTGAAGCGGCACATGGCCTCGCATCGTGACAAGTCCGTGGTGTGCGAGGTCTGCCAGGAGGAGTTTCCCGACGGCCGTACGCTGTCCAACCACCGGCACTCGCACAGCACCACGTCGCCGGGAAAGCTATTCCCCTGCCACGAATGCGGTAAGACTTTCGGGTCACGCAGCTCCCAGCAGATCCACGTGCGTATCCACACGGGCGAGCGACCCTACGGCTGCCGTTACTGCTGGAAGGCCTTCGCCGATGGCGGAACGTTGCGCAAGCACGAACGCATCCACACGGGCGAAAAGCCCTACGCCTGCTCTGTCTGTCCGCGCGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGTTCCCACCACTCGGGGCTGGATGCGTCGACAAATACATACCACTGCACGGTCTGCGCCGAGGATCTGGCCTCGTCCAATGACCTCATACAGCACCTCATCCAGCACAGCGATTCGAACACCGCCAAGCAGCGTCAGCCAGTGACGGGACCGCGAAAGTACAAGCGTCGACGCAAGCTGCAGCCCCACGAGATAGCGAACATGCGGGCAGAACACAAGGATGCTAACGGCGGCGGCGGCGACGAGGAAGAGATTCTGGGAGGCGAAGGTGATGGCGATGCCGATGGCGATGGCGATGGAGAGGAGTATGCCAGCGACATCGACCTTTGCGACTTTGACGTGGAGAATGTGGACGATCTCTTTGAAATGGCCGAGTCGCCGCCCAAAAAGGAGAAGCGCAAGAGGACATCGGCAGTGGCAGCCACAAAGACAGAACCTAAACCTGTTTCCAATGGCGGCGGATCGTCGGTGAAGCCTGTCCAGGAAAAAAATAAGGCCAAGCTGCGCTATGACTCTACCTGCAGTCAGCAATCAGATCGCATTTGGGAGGAGAAGTTTCTGCAGGACAGTCATGTGGCGCTCTTCCAAATCGATTCGCTGGTGGTGGTCAACGACACACACCTCCAACCCGCGAGCTCAGCATCCATGCCCAAGACGAGAGGTGGTACCAGGCAGCACCAGCAGCAACAGCAGGCCAAGCAGCCCGTTGAGAGAGCCGGAAGCTCCAATCCCTCGGCTGCAAGCTCAGTTGCCACATCCCTAGCCTCCGCCTCCGCCTCTACATCCACTTCCAGCAATCGTAGCAGGAAGAAGGCGGCCGCTGCAAAGACAGCTGCTGCCCCACGACCACGTATGATTCACACGGAAAAGGCCAAGGTGACGGCCAAGGGAAATGCCGGTGGAGATTCGGCCAAGAAGACACGCTCCAAGACGTACATCACCCGCACGGAGACGAGCAATCTGAGCAGTCTGGACAAGTCGCGAAGCAGAGCGTCTAACATCGTGGATGACTACGAAATCATTTCACCGGCCACCCATCCGCCCAATCAGATCAGCTCCAGTCCGCTGCATATCAAGCAGGAGCAGGAGCAGCAGCACCGCGTCCAGATGATGTACGATGACAACCTCCTGATAGACGCTGCCCTGCTGCGGGAGAAGACTTACGAGAAGTTCAACCCGAGCATTGTGAACGATCTGGAGGAGATCCTGCGCTCGCCGCTCAAACACGAACGCAACACCCGCCTGCGATTCACCAGCGAATCCTCGACCACGCCACAGTTTCTACCCGAAGAAGAGCAGAATCTGATTAAGATCGAGCCCACGTCTCCGGACTTGCGGGAGATGCTGGAGAGTCAGAGTCAAAGGGTTAGAGTACCAAGCGGCAATACACCGTCGCCCTCGTTTTCCTCCGCCAGAACTTCCCGTCATCGTATGATCACTGCCAGTGGACCAAGGGCAGGGAACAAGAGATCCGCAGGAGGAGGAGGAAGCGGTAGCACATCCTCACCTGCCCCAGAAGTGCCGGCAAGGAAAGTGAGCACTGCGGCCAGTAAGGTCGGTAGCTCGTCCTCATACCTCAATTACGGGGTGGATGCCTACAATGTGAACGTACCTGCCAGCACCAGCACTGCCGATGTGGGCAGCGGATTCTTCTCCATCTCGGAGGTCGTGTCGGCCGCCGATGCAGCTGATGCGGCGGCCAAGGCGGCGGCGGCCGGGAAAACGGAGCGGAAAACGCGAAGTTTCGAGTGCGAAATGTGTTCGGCCATCTTTTAT
Protein Sequence: MNNQDYGGIQWIRHHPAAGDSSETDLLEQEDADGDGMVSGGDGDPDGDGDADADLDHMAAENLIFMARDGQLGEIIAASEGAVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVEHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAVPVSSIKFEHQGHRQMDDHYYEQEWPLYQQQQQHEQEQEQEQVQHEQMLQQEQQQLVCNSEVQFVASYTATVAPPPAPSRGRISRLKPKEESSQFIVITDKSTSSELQDYMASEPVPQPMVPTSQPMAIDPPPAPAPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKMHQFEESNSEYDPASGDDSASETSEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDHNSTVAAGDGSSSDIIANGDQAKDGNGGGHCCQTCGKSFPSASEMLSHAEIHARFPPFKCVLCGVSFYEEQVIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDASTNTYHCTVCAEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIANMRAEHKDANGGGGDEEEILGGEGDGDADGDGDGEEYASDIDLCDFDVENVDDLFEMAESPPKKEKRKRTSAVAATKTEPKPVSNGGGSSVKPVQEKNKAKLRYDSTCSQQSDRIWEEKFLQDSHVALFQIDSLVVVNDTHLQPASSASMPKTRGGTRQHQQQQQAKQPVERAGSSNPSAASSVATSLASASASTSTSSNRSRKKAAAAKTAAAPRPRMIHTEKAKVTAKGNAGGDSAKKTRSKTYITRTETSNLSSLDKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVPSGNTPSPSFSSARTSRHRMITASGPRAGNKRSAGGGGSGSTSSPAPEVPARKVSTAASKVGSSSSYLNYGVDAYNVNVPASTSTADVGSGFFSISEVVSAADAADAAAKAAAAGKTERKTRSFECEMCSAIFY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -