Dtsa014400.1
Basic Information
- Insect
- Drosophila tsacasi
- Gene Symbol
- -
- Assembly
- GCA_018904565.1
- Location
- JAEIHY010020023.1:40841-42259[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 6.2e-06 0.00062 20.4 5.0 1 23 195 217 195 217 0.98 2 9 4e-07 4e-05 24.1 0.5 1 23 223 245 223 245 0.99 3 9 1.2e-05 0.0012 19.5 1.6 1 23 251 273 251 273 0.98 4 9 2.8e-05 0.0028 18.3 2.0 1 23 279 301 279 301 0.98 5 9 7.8e-05 0.0078 16.9 1.5 1 23 307 329 307 329 0.98 6 9 0.00027 0.027 15.2 1.9 1 21 345 365 345 366 0.96 7 9 1.8e-07 1.8e-05 25.2 1.8 1 23 373 395 373 395 0.98 8 9 1.4e-05 0.0014 19.3 0.7 1 23 401 423 401 423 0.95 9 9 3.5e-05 0.0035 18.0 5.8 1 23 429 451 429 451 0.97
Sequence Information
- Coding Sequence
- ATGGAGGACACTTGCCGAATTTGCAGGGGAAAGCCGGAAACCTTGGTTAATATATTTAATGGGACGCCTTCTCAATCGGAGGTTTCCATTGCTGATATGATTTCCAAATATACGGGCTCTTCCGTTTCCAAGGGGGATTCCCAGCCAGAAAGCATTTGCTCGCCGTGCCTACAGGATGTCCGAAATACGTATCAGATAAAACAATCGTATGAGGAGAGCCGGGAGCACCAGAACCATTTAACGGATGAGGACCCCACGCAGATTGAATTTTTTACCATAACTGAATTCAAATGTGAGAGCGACGAGGAAGAAATCCAAAATTTTAATTCTGAAAATCACAACGAAGGTGTCGACCCGCAGAATTTGGAGCTATATGGAGACTATAATGACTTCCAGGTAAAGAATGAGCCGCTTGAAGAAAATTCTGTCGAAGAAGAGGACTGCCATGTCGAACAAACCGAATTGCAAGTGAAAAGCGAAGAAGTGGAATATGATGAAGTAGAGGATGATAATGATAACGATAAGGATTATACCGACGAAAGTGAGGTCCTCAGCAAAGGACATGCGGGGGAAGAGCTGCCCTTCAAGTGTTCCCACTGCTCAAAGTCCTTTCCAGACCGACGCAAACTCAAGAAGCACATCCTGTATCACAACAGTAAAAAGACATACCAGTGCTCGCAATGTCCAAAGTCTTTTCTGTCTCCATCTAACCTTGAGAACCACGTGCGCACACACACCGGAGAAAGGCCGCATAAGTGCTCCCAGTGCCCAAAGTCGTACGCCCAACTATCTGCTCTTAATACACACTACCTCAGTCACACCGGTGAAAGGCCACACAAGTGTCCTCACTGCCCGAAGGCCTTTCTAACGTCACCTAGTCTGAAAGTTCACGTGCGAAGTCACACCGGAGAAAGGCCCTACCAGTGCACACTATGCCCGAAGACTTTCCTGAGACGCTCCTACCTGGACAACCATTACAACGTCCACACCGATGCAATAAAAGACAGTGAGAGTCTCGCGGGAATGGAGGTCTTCAAGTGTTCCCACTGCCCGAAGACTTTCTTGAAAGAAACCTGGCTCAAGAAACACATTCGCAATTATAGCAGCGAGAAGGCGCACAAGTGCTCCCTCTGCCCGAAGTCCTTTATTTCCCGAAACAATCTGGAAGACCACATCCGCACTCACACGGGCGAACGACCCTTTCTGTGTACCACATGTCCCAAATCGTTTTCAAGTACCATAGGACTCAGGCGGCACGTCCTTACGCACTCTACGGAGAAAGCACACCACTGTCCCCATTGCTCCAGCTCGTTTGCCGTGCGGGAGAATCTGACGAGACATATGCGCTCACACTCGCCGTCCCTCAAGGGGCCGATGGGGAGTGAGCAAGTTTTGGATGAGGAACTACTAGGGCAGTAA
- Protein Sequence
- MEDTCRICRGKPETLVNIFNGTPSQSEVSIADMISKYTGSSVSKGDSQPESICSPCLQDVRNTYQIKQSYEESREHQNHLTDEDPTQIEFFTITEFKCESDEEEIQNFNSENHNEGVDPQNLELYGDYNDFQVKNEPLEENSVEEEDCHVEQTELQVKSEEVEYDEVEDDNDNDKDYTDESEVLSKGHAGEELPFKCSHCSKSFPDRRKLKKHILYHNSKKTYQCSQCPKSFLSPSNLENHVRTHTGERPHKCSQCPKSYAQLSALNTHYLSHTGERPHKCPHCPKAFLTSPSLKVHVRSHTGERPYQCTLCPKTFLRRSYLDNHYNVHTDAIKDSESLAGMEVFKCSHCPKTFLKETWLKKHIRNYSSEKAHKCSLCPKSFISRNNLEDHIRTHTGERPFLCTTCPKSFSSTIGLRRHVLTHSTEKAHHCPHCSSSFAVRENLTRHMRSHSPSLKGPMGSEQVLDEELLGQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00612945;
- 90% Identity
- iTF_00485285; iTF_00617780;
- 80% Identity
- -