Dtsa018370.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tsacasi
Gene Symbol
Paris
Assembly
GCA_018904565.1
Location
JAEIHY010019604.1:9372-12216[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.11 11 6.9 0.6 5 23 122 140 120 140 0.96
2 14 0.001 0.1 13.4 0.5 1 23 144 166 144 166 0.98
3 14 1.1e-06 0.00011 22.7 2.9 1 23 172 194 172 194 0.99
4 14 2.1e-08 2.1e-06 28.2 2.2 1 23 200 222 200 222 0.99
5 14 2.8e-07 2.8e-05 24.6 5.5 1 23 228 250 228 250 0.98
6 14 4.2e-06 0.00042 20.9 3.7 1 23 256 278 256 278 0.99
7 14 7.4e-06 0.00074 20.1 1.5 1 23 423 445 423 445 0.99
8 14 2.1e-06 0.00021 21.8 1.5 1 23 453 475 453 475 0.98
9 14 0.00013 0.013 16.2 8.2 1 23 481 503 481 503 0.99
10 14 5e-08 5e-06 27.0 2.6 1 23 509 531 509 531 0.99
11 14 0.00041 0.041 14.6 9.3 1 23 537 559 537 559 0.98
12 14 0.003 0.3 11.9 12.8 1 23 565 587 565 587 0.99
13 14 2.2e-06 0.00022 21.8 2.2 1 23 593 615 593 615 0.99
14 14 0.00065 0.065 14.0 1.9 1 23 621 643 621 643 0.98

Sequence Information

Coding Sequence
ATGGAGGGGATCTGCCGTGTTTGCCTGGGAAACCCCACCGGAGACTTGGTTAACATATTTGATTGCAAGCCTCGGACTCGAAGCCCCTGCATTGCCGATATGATCGCGCAATGCACTGGCTTTGAGGTTCAACGCGGCGACTCCTATCCGGAAACCATTTGCCCAACTTGCCTGAAGGATGCACAAAATGCATTTGAGATACGGGAAATCAGCCAGCGGAGCCATCAGTTCTTTTGCCAAGTGCGGGATGAGGGCATTGAAGAAGCCTTGTGTGCCTTGCTTGAGGAAGAAGATTGGGATATATCGGAAAATGAATCAAAAGATTCGAAAACGCATGACAAGAAACCAAAATTCAAGTCCCGAAAGTGCAGCGAAACCTTCAACTTAAAGGCGGAGTGGCTGAGGCACAAGAGATCGCATTATAAAAACTTTCCCTGCGTTCTCTGCCCGAAGGTGTTTGCAACTAAATTGGAGCACCAGGTACATATGAACACCCACACGGGCAAGCGTCCGTACAAGTGCACACACTGCTCGAAGGGCTTCGCACAAGACTCCACTCTGCAGTCGCACATTCGGACGCACACCGGCGAGAAGCCGTACAAATGTGACCAGTGTTCCAAATCCTTTGTCAAGTCATCGGATCTTCGCCGGCATATCCGCACCCACGAGGGAATCAGGCCGCACAAGTGCTCTGATTGCTCGAAATCGTTTACGAGGAAAGCGCATCTGCAGGATCACATGAAGATTCACACGGGCGTGCGACCGTACAAGTGCTCCAAGTGCTACAAGTCCTTTAGTACGGGCACCACGCTCAAGGATCACATGAAAACTCACAGTCGGACAAAGACCATGGAGCGGATCTGCCGCGTTTGCATGGGAAACCCCACCGGAGAATTGGTTAACATATTTGATTGCAAGCCTCGGACTCGAAACCCCTGTATTGCCGACATGATCGCGAAGTGCACAGGCTTTGAAGTTCGACCAGGCGATTCTTATCCAGAAACAATTTGCCCTCCATGCCTGAAGGATGCACAAAATGCATTTGAAATACTGCAAACTAGCAAGCGGAGCCATCAGTTCTTCTGCCAAGTGCGGGATGAGGGCATTGAAGAAGCCCTGTGTGCCTTGCTCGAGGAGGAGGATTGGGATGTATCTGACAATGAGGACGAATGGAAGAATGTAAAGCGGGTTGTTGGCGAAAACAATGAGGAAGATGAAAACAATAATGAGGACCATCAAGCAGAAAGTCTTAAAGCTGAAACTTCCTTTGAATGTAACGAGTGCCGGAAGACCTACAAGCGGAGAGTTCCCTGGCTGAGGCATATGCGGACGCATTTGGTGGGTGGACCAGAACCATTCTCCTGCAGTCACTGCCCAAGGGTATTCCGAGCTAAAATTCAGCTACAGGTACACATGAACACACATACGGGCGAGCGGCCCTACAGTTGTTGCCACTGTACGAAGAAATTTGCCCAGCATGCTACGCTGCAGTCCCACATCCGGACGCACACTGGAGAGCGTCCGTTCAAGTGTTCCCAATGCAACAAGAACTTCGTTAAGTCTTCTGATTTGCAGCGACACATCCGCACTCACTCAGGTCTGAAGCCACACAAGTGTTCCCAGTGCTCGAATTGCTATTCAAGGAAGTCTCATTTGGAAAATCACCTCCGTTCTCACACGGGCGAAAGACCGTTTAAGTGTTCTCACTGCTCGAAGTCCTTTCAGCAGAAGCATCATCTGCACGAGCACAACCGAACGCACACCGGTGAAAGGCCGTTCAAGTGCTCCAAGTGCCCTAAATCCTTTAGTCTGAGCAACACCCTGAAAAATCACTTGCTCACGCACAGCTCAAAGAGATCATTTAAGTGTAGCCGCTGTTCTAGTGCATTCAAGCAAAGAAGATCGCTAGTAAAGCATGCCCTCACTCATAGTTGA
Protein Sequence
MEGICRVCLGNPTGDLVNIFDCKPRTRSPCIADMIAQCTGFEVQRGDSYPETICPTCLKDAQNAFEIREISQRSHQFFCQVRDEGIEEALCALLEEEDWDISENESKDSKTHDKKPKFKSRKCSETFNLKAEWLRHKRSHYKNFPCVLCPKVFATKLEHQVHMNTHTGKRPYKCTHCSKGFAQDSTLQSHIRTHTGEKPYKCDQCSKSFVKSSDLRRHIRTHEGIRPHKCSDCSKSFTRKAHLQDHMKIHTGVRPYKCSKCYKSFSTGTTLKDHMKTHSRTKTMERICRVCMGNPTGELVNIFDCKPRTRNPCIADMIAKCTGFEVRPGDSYPETICPPCLKDAQNAFEILQTSKRSHQFFCQVRDEGIEEALCALLEEEDWDVSDNEDEWKNVKRVVGENNEEDENNNEDHQAESLKAETSFECNECRKTYKRRVPWLRHMRTHLVGGPEPFSCSHCPRVFRAKIQLQVHMNTHTGERPYSCCHCTKKFAQHATLQSHIRTHTGERPFKCSQCNKNFVKSSDLQRHIRTHSGLKPHKCSQCSNCYSRKSHLENHLRSHTGERPFKCSHCSKSFQQKHHLHEHNRTHTGERPFKCSKCPKSFSLSNTLKNHLLTHSSKRSFKCSRCSSAFKQRRSLVKHALTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00524534;
90% Identity
-
80% Identity
-