Basic Information

Insect: Drosophila truncata
Gene Symbol: ZNF541
Assembly: GCA_008042515.1
Location: VNJQ01003259.1:70959-80800[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.032 2.8 8.6 1.7 2 23 179 200 178 200 0.97

2 6 3e-06 0.00026 21.3 1.3 1 23 206 228 206 228 0.98

3 6 0.0003 0.026 15.0 2.5 1 23 234 258 234 259 0.94

4 6 0.0005 0.044 14.3 0.8 2 23 539 560 538 560 0.97

5 6 0.14 12 6.6 0.0 1 19 1695 1715 1695 1717 0.94

6 6 6.7e-05 0.0058 17.1 0.8 1 23 1732 1754 1732 1754 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.032	2.8	8.6	1.7	2	23	179	200	178	200	0.97
2	6	3e-06	0.00026	21.3	1.3	1	23	206	228	206	228	0.98
3	6	0.0003	0.026	15.0	2.5	1	23	234	258	234	259	0.94
4	6	0.0005	0.044	14.3	0.8	2	23	539	560	538	560	0.97
5	6	0.14	12	6.6	0.0	1	19	1695	1715	1695	1717	0.94
6	6	6.7e-05	0.0058	17.1	0.8	1	23	1732	1754	1732	1754	0.98

Sequence Information

Coding Sequence: ATGTGCAGCGCCTCCGTGGGCACCGAGGGATCCGTGACTCTGCAACTGAGGGATGCCAACGCCTTGGAGGCAGCCTCAGCCTCTACGAAGACAGCGGGAACAGCATCTAGCGGAGCAGCGACAACGTCCACGAATGGCGCTGCAACTGCGTCAGCGACGACGCTAGACAATGCGCTGACCATCGGCTATCCGGATCCGGAAATGTTGGCAGATGTCTTGGGCACCATTCAGACAGCCTCACTTAAAAACCACAACAGCAACTCAATCACAGCAGTAACTTCAAGCAATAGCTCGGCCAAATCGAATGTCGGCAATCATCTGAGTAATCCCAATAAGATAACCATAACCAGGCGAAGTAGCTCCGGACACGGTCATAGCAGACATGTGCCCGCTTCCGGCGGAGTAAGCACTGCGGCAGCAGTCACCAGCACCAACTCGTCAGGGATTGGGATTGGCATTGGCGGGATCATCAGCGTTGAAGCACCACGCAAGAATCGCCCGAAATTATCCTCACCGACGCGACACGGTCCGCAGCAGTGTCAGACTTGTTGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAGCGGAAATACATCTGTGCGCTTTGCTCAAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACTCATCGGAACAAGAAGCCTTACGAGTGTAAGGCGGATGGCTGTGGCAAATCCTACTGCGACGCTCGCTCCCTGCGGCGGCACTCGGAGAACCATCATGCCGGTGGAGCGACCACGCCCACAACCACCAGCCAGCAATCGCTCTCGCCCACCGCCAGCTCGAGCGgagcgagcagcagcagcagcagcggcgtgGGAGTAGCCACCAGCTCGCTGAGTCTCTCGCCGGCCACAGCCAGCGGGGATGCCAGCTCCCCGGACGGAGCCACCTGCATACGCACCTACATCTCCACAGGCAGCTCGGTGGTGGATGCGGCCACCGGCATCGCATTGTCGGACGAGCAGATCAAGGCCATGAACCTGCCCATCAAGACGGGTGTGACCCTGCTTTCGCCCACCACTTCGACATCTTCAAATGCCTCTTCTACggcctcctcgtcctcgtcctcagCCTCCACCTCCGCCTCCATCTCATCGCTCTCCTCGGCGACATCTGGCATAGGTTTGACGGCAAGCTCTTCGCCCTCTGGCAGCGGCACCGTGATAGCCACCAGCTCGCCAGCGCCGACCATCACGCTCAGCGATGGGATGAGCCTCGAGGGCGAGGGTCTGACCAGGGAGCAGCTGGACCTCATCAGCAAGATCATGCAGCAGACAAAGCAGACGAGCGCCCAGGTCACCGTCTCCTCGCCCACCAGCGTCAGCTCCTACAAGATCAACACGAACTCGGCGCCGTCGCAGGCCAGGCCGAGGACTTGGAACATGCAGTtgCTCAATAATGCCCAGAATGTGACGGTCACTGTTGAGGACAACACCGATTTGGTGGCTCCTTCCTCTAGCTCCCCCGTGGAGGTCAAGGAGGAGGAACTAAGTCCCCAGCTAGTGGCCGCCATCAATCCCCACCTGCTCAACATTGTGAAGCTCGACAAGCCCGTCGAGTGCAATCTGTGTCACCGAAAGTTCAAAAACATACCCGCCCTCAATGGGCACATGCGTCTCCATGGTGGTTACTACAAGAAGGATCCGGAAACCAAGCGCAGCGAGAAGAAGGACTCCAGTGGTCCGCCCCTGCAGACGGCCAGCATTGGAGTAAGAGCCCTCATCGAGGAGAAGATCATTAGCAAGCGCAAGGATATGACAAAGGGCTCATTTGTGGTTCCTGCACCGCCTCACAGCagcggcaccaccaccaccctgCGGCGATCCATCAGCGACCTGGAGAGTTTCCTTAATCCCAAAAGCAGCTCCAGTGGTCACACCCAGACCTTGACCACCGGCACTGGCACCACCACGGCGGTGCTTCCGGCGGCCACCACCATTAAGAGCAGCAACGGGCTCAGCATTCAGCAGATCGGTTTGCCACAGAGCATTGAGATCTTCAGCGGTGGCCAGAAGCAGGCAAAGACTCTGAGTCTGGGCAGTGGCACCAATACCATCACTATAACCACCAATAATGtgcccaccaccaccacaatgAGTGCTCTAACTGCCTTGAAGGCTGGCGGCACCATTAGCGGCATTTCCACGGCCACCAACACGGATCCCAAGGATTCCACGCTGATAGAGCTTCTCAAGCGGGGCACACGCATTGCAGTGACCTCAAAGAAGGCCCAAGCCCAGTGCCAAACTACATCCGGTGTGCTGATGACATCCAGTTCCACGGCCACGCAATCGATGGGAACCCTCACCGAGCTGACCACCATTGGCGGGAGCAGTGTCCAGACAGTGGGCCGTCAGATCATCACGAACAACAATCGCACCGTGATCATACCCTCCGACGTTCAGGTGGTGTCCACCAAGAGCAAACTGAGCAGCCTGAGCAGTCTGGTGAAGAGCACTAGCACCAGCTCCAGTGTCACCAATACCAGCTGCTCCTCGAGCAATATCTCGCTGGCAGACGGTACTCCACTCTCGCTCACCATAGCGCCCAGTCAGGAAGGTTCCAGTGGCGGAGTTCCAAGTGGCACTGAGGGCGTGATCACGAGCGGGGGCGGCGGTGTCTACACAGTAACCTACACCAGCGATGGCACCGATCTCTTCGACGACGCCGAGGTTTACAACGTATCCGACACAGAGATGCTGCTGCAGACAGTGGACTCGATGGAGTTGCTGAACGATGACGAGGAGGAGCCGCAAATTAAGAGCGAACATTCCGAGGACTTTGCCCTGCTGAGCGAGGCCGGTGAGAGTGAGCACCCTCAGCTGGTGAAGCTGGAGACGGAGAGCGGGCAGAGCGGCTGCAGCTCCGTAGGAGGTGCGGGAGCGGCAGCCAATACCACGCCGCTGCCCACCTTCCAGCAATTCCATTCCAAGGAGCTGATCATGCAGAACAGTTCGCAGATCCAGGCCATAGCCAGCATGCGGGCCAGCGGAAATGGTGCTGCAAGTGGCGTCCTGGCCTCGCCGCTCCACTCACCGCTGGCTTATCCCACGCCGCCATCGAGCCACGAAAATATGGCCCAGAGTTCGCCTTTCATTGAAGATGCGGCCGCCCAGTTTGTAGATGCCAGCAACACCTTCTTCGGTGACAAGACGGACTTCTCGCACATCTACTTCAAGACGGACGAGGGTCAGGCCACCATCGAACAGATGAACGAGCACGACAACGAGAAGATCCTTAAGCTGAAGTCGGTGCTGGAGGAGAGCAGCTTCGATCCCTCCATCAAGGTGGAGGATCTGCTCAATGGCACCGACGACGACACTGAATGCGATCTGCGTGAGTTTGCCGAGACGAATCTGTCGTTTCTGGACGAAGACCAGGAGTTCCTTAACGACTCCCGTAATGCCACCTCACCACTCTCGGAATCCTTCTTCACCAGCGGCATTGGCTCGGCGGAGGATGTGAAGCAGGTACTGCGAGAAGTTCTGCCAGATGAGAACATGCAGCTGCAGTTGACCAGCGAGCAGCAGGGCGAGAATATCATCGATCTCTATTACCTGCCTGGCCTGGGTTTGCAGTCCCAAATGATGCCCAACTCTGAAGATCCCTTGTTGTCCTCATCGCCCAGGGAGTTTggtcagcagcggcagcagatgAGCAGCATGCAGCCcctggagcagcagctccagcaaaATGGCAACCTgtatcagcaacagcagcagcagcagcagcagcagcaggagcagccacagcagcagctccaagaACAGCCGCAGCAAGAGCaaccacaacagcagcagcagcaacaataccAGCAAATCATTCTCCCCCAGCAAGCGTCAAATCAGGGAGAATCCCTGCCAGCGGTGGTGCAGCAGCAAACCGATTTCATGCTGCCCCTGGTGGGAGGACATGGATTCACCCATGTCACCTCCGGTCAGACCCAGTACGTGGACAATGGCCAGGGTAACATGCAGGAAATGCAGCCACTCAATAGCCTGCTGCAGCCGCTGCTCTACCAGGGAGCCGTCACTTCCAATGGCATAGCCGCCGGCGGACACGAGAGTCTCTTGCCCACCGATTGCCAAATGAATGCCAATCAGGGGCAGACAACGACTACTTTGGATGCCGGTTTGCTGTTCGCCTGCggcaacaccaccaccatcaccaacAGTACAGCCACGACAATGGGTAATAAATCCCTGCTAGCCTCGGGGCCCTTGCCCGGTACTGTGGCCAATCTGCAGCCGCTGTCGAACCAAACCAATTCCATTCTGAAGCGCCGCCTGCGCTCCACTGCGCCCCAGGAGACGCACAAGTTCTCCAAGTTCCACACGCTCTCGCCGCACCGCTCCAAGCTGCGTAAGCCCTCCCGCACCCATTATACGCCGGCTCCGATCCTGAATCCGGACCGCAAGGGCACCGGCCTCTACTGCAGCGTCCGCAAGCAGTTGGGCCTGAGCCAGGGTCTCTTCGATGGCTTCGACGATGACTTTGGGGATCCGGTGGGCCTGGTCGACTTCTCCGACGAATCGAAGGTGAATCTGGGTTCCACTTACCAGGCACAGATACCCAGCTGCCGGCCGCCGGAGGAGGCTGCCCAGGATCCACTTCTCGCCGAGTTGATGTGGAATCCGGAGGTGCAGGAGGACGAGAAAATCCTGATGCGCTACATTGATCTCAGCAAGTCATCGGCCGTGCCCATGGGCAGTCATTCCGAGGAGGTGGCGCTCCAAACGCTGCTCAAGGCCAGGGGCAACTCGGCGGCTGCGGTGCTCACCCTGCTTCAGACGCAATCCGGCGCCTTCCAAATGAAGTGGACGGCCTATGAGCTGGAGCAGTTTCTGCGAGGCTTGGAGAAGCATGGCAAGGATTTTGGCAAGATAGCCAGCGAGCTGCTCACCAAGTCTTCTGGCGAGTGTGTGCAGATGTATTACTTCTGGAAGAAGCTGTGCGTGGACTACAAGGTGTCGCACCTGAAGATGGAGCCGGTGGTGGTGATCACACCCGCCGTGGAGAAGCCCTATGTGTGCGAGATTGCCGACTGCTCAGCGAGCTTCAGTTCGAAGGCGGCGCTGCACGGCCATTCGGAACAGGGAATTAACGCCATACCAGGTGCCGCCAAGGAGGGCGAGTTTCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTGAAGAGTCGCAGTGCGCATATGAAAACCCATCGTGTCCAGGAGGCGGATCAGAAGCATCAGCAGATAAGCCATCAGTCAGCAGCCGGAACAGCAGGATCAGGAGTGGCCCCTGTGGCATCAAGCATCACTACATCGTCGTAG
Protein Sequence: MCSASVGTEGSVTLQLRDANALEAASASTKTAGTASSGAATTSTNGAATASATTLDNALTIGYPDPEMLADVLGTIQTASLKNHNSNSITAVTSSNSSAKSNVGNHLSNPNKITITRRSSSGHGHSRHVPASGGVSTAAAVTSTNSSGIGIGIGGIISVEAPRKNRPKLSSPTRHGPQQCQTCCKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHAGGATTPTTTSQQSLSPTASSSGASSSSSSGVGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSSSSASTSASISSLSSATSGIGLTASSSPSGSGTVIATSSPAPTITLSDGMSLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTNSAPSQARPRTWNMQLLNNAQNVTVTVEDNTDLVAPSSSSPVEVKEEELSPQLVAAINPHLLNIVKLDKPVECNLCHRKFKNIPALNGHMRLHGGYYKKDPETKRSEKKDSSGPPLQTASIGVRALIEEKIISKRKDMTKGSFVVPAPPHSSGTTTTLRRSISDLESFLNPKSSSSGHTQTLTTGTGTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGQKQAKTLSLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTATNTDPKDSTLIELLKRGTRIAVTSKKAQAQCQTTSGVLMTSSSTATQSMGTLTELTTIGGSSVQTVGRQIITNNNRTVIIPSDVQVVSTKSKLSSLSSLVKSTSTSSSVTNTSCSSSNISLADGTPLSLTIAPSQEGSSGGVPSGTEGVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSMELLNDDEEEPQIKSEHSEDFALLSEAGESEHPQLVKLETESGQSGCSSVGGAGAAANTTPLPTFQQFHSKELIMQNSSQIQAIASMRASGNGAASGVLASPLHSPLAYPTPPSSHENMAQSSPFIEDAAAQFVDASNTFFGDKTDFSHIYFKTDEGQATIEQMNEHDNEKILKLKSVLEESSFDPSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSEDPLLSSSPREFGQQRQQMSSMQPLEQQLQQNGNLYQQQQQQQQQQQEQPQQQLQEQPQQEQPQQQQQQQYQQIILPQQASNQGESLPAVVQQQTDFMLPLVGGHGFTHVTSGQTQYVDNGQGNMQEMQPLNSLLQPLLYQGAVTSNGIAAGGHESLLPTDCQMNANQGQTTTTLDAGLLFACGNTTTITNSTATTMGNKSLLASGPLPGTVANLQPLSNQTNSILKRRLRSTAPQETHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCSVRKQLGLSQGLFDGFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPSCRPPEEAAQDPLLAELMWNPEVQEDEKILMRYIDLSKSSAVPMGSHSEEVALQTLLKARGNSAAAVLTLLQTQSGAFQMKWTAYELEQFLRGLEKHGKDFGKIASELLTKSSGECVQMYYFWKKLCVDYKVSHLKMEPVVVITPAVEKPYVCEIADCSASFSSKAALHGHSEQGINAIPGAAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEADQKHQQISHQSAAGTAGSGVAPVASSITTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00572137;
90% Identity: iTF_00612749;
80% Identity: iTF_00612749;