Dtru008142.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila truncata
Gene Symbol
-
Assembly
GCA_008042515.1
Location
VNJQ01001885.1:55250-58326[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.4 35 5.2 4.2 1 23 171 194 171 194 0.96
2 9 1.3 1.2e+02 3.6 1.4 3 23 248 269 247 269 0.90
3 9 0.00019 0.016 15.7 5.2 1 23 659 681 659 681 0.97
4 9 0.00026 0.023 15.2 0.3 1 23 687 709 687 709 0.98
5 9 0.00047 0.041 14.4 0.9 1 23 715 737 715 737 0.98
6 9 2e-07 1.8e-05 25.0 0.5 1 23 743 765 743 765 0.99
7 9 6.7e-06 0.00058 20.2 0.6 1 23 771 793 771 793 0.99
8 9 2.4e-06 0.00021 21.6 0.6 2 23 800 821 799 821 0.97
9 9 0.00096 0.084 13.4 0.2 1 23 827 850 827 850 0.97

Sequence Information

Coding Sequence
ATGCTGAAAATGACAAATGTTGCTGGGCCGGTGCAAACAATGAAGAAAAACGCAAACGGCAACGACAACGATGACTCCGAGGAGTCCGACATAGACATGgatgaagaggaggaggaggaggaagaggaggacgATCTGCCCGACGATGTGGTGCTACAGATCGACAGCGAGGACGAGGCGGAGCTGGAGGCGCAGCGCATTCGCTTGGTGCgcgaagaagaggaagaggccaaggccaagataacaacaacaaagcagGAGGCGAGAGAAGCGCAGGTCAGTAACGGTAGAGCGAATGGAGTGGTGAagaaggaggtggaggagaagTTCGAGATCGGAACAACGAAATCCGGAAAGGCGGCTACCAAGCGCAAGGTTCGCGGCAAACCCGTACGCCGGACCTCGGTGAGTTCTCAGGCCTCCAGTGTCGGCTCCGTTGCGTCCAGCGCAAGCGCTGCCTCTTTGGTGGCCGCCCAGGTTCTGGCCGACGAGAAGGCGCGCAGCTTCATTTACAGCTGCACGCAATGCAGTCATCACTACGCCGACCGTGTGGTCCTCTCACGGCACTTCCAGAAGGAGCATGCCGAAAAGCCCAAGCGAAAGCGTGGCCGAAGCAAGCTCGTCAGCCCTGAAGAGGATACACCTGCGGTTTCTAGTCCTCTAAACCTCCGAGCAGAGGAGATCAGCCTACTTAAGCCCTGCGCCCAGTTGCTCATGCAGGGCGAGTCCCTGCTGCAACTGTGTCTTGCCTGCAACTCACAGTTTGTGGACCAGCAGCACTTCCAAGAGCATCTTAGCCAGCAGCATGGTTACTtcaagctgctgctggtgcccAAGGAAGAGCCTAGCGATCTACCGCCATTGGCCATGGTCACCATTCCGGGGGCCCTGGCCTTAGGCAAGTCCAACCAGCAGCTTCAGCTTCCCATTCCGGCCCCAGAGACCCCGCCTCCCGAGCAGGATGCCAAGGAACCAGCAACGACTACCCAATCCAATGGCAGTGTGGTGGCGTCTAACGATAAGGAAGGCCTCCATATGATAAGCGCCATGGTGGCAGAGATTGCGGCCGAGAGGGTCAAGAAAACCAGCAGCCCCAAGGTCAGCAAAATGATCATCAAGCTGCCAACGGCAGCCACCAAAAGGGGCAGAAAACGCGCCAAGCCCGAGAAGACAAAGAGAAGGGATATTGCTGaaatgctgccgctgcagccgGTGAAATCAGAGAACAATCAGCCTAGGTCGGAGCAACCACACCCAATGAGAATTGCTGAGGGACCGCAGGAGACAAAGAAACCCGAACAAGATGATAATCAGCAGTCGCTGAAGGAAGCTGCAGAGGATAAGAGAGCTGTTGAGATTCCTCAGCTGTTAGAGAACGCTGATAAACATCCtctaaaaaatgttgctcttGGGGACAAATCGGAGAAAATGGCAGAGGATCCTCAACAGCCAAAGGAAATTGAAGAGCCAAAGCTGCCAGAAATCAAGGAGCCGTTACCTGAAATAGTTGAGGAAACTCAGCAGCCAAAGGGAGTTAAGGAGCCTCTCCAGCCAGGAAAATTGAAGAAGTCTCAGCAGCCAGAGAAATCAAATACGGGTGAGCAGCCGAAACCAACCGGAACACaagagaaggagcagcagccatcACCCCAGCCAAATCTTAATCCATCCAAGCGCAAGCGCGGCCGCAAAGAGCAAAAGTCGCCAACGCCGCCAACCGTCCCGTTGGAagacaaagaaattaaagaggaGTCTGAGACCACAGAGCGACGCATGCGCAAAAGCCGAAACCTTGTGGATTATGTAGTGGAAATTAAAGATGAAGAGGACCCCGATGAAGGGGAGGAAGCAGAGCTGGATGAGGATTGCTCCGAAACAGTCTCACCAAACACCAGCTCCACGGACGACAGTTTCACCTCGATCAAGCGTGAATCATCAGAGGAGTCGCAACGCAATGAACCTGGAGGCAGTATACACACGTGTAATTTCTGCGGCAAGACGTTCAAACGCTTCTCCCGTATGCAGGATCATCTGCGTCTCCATACCGGCGAGAAGCCCTATGTTTGCGGACAGTGCGGCAAGGCATTCCGCTTGAAGATGCGTCTCGTTGAGCACCAACTGCGCCATCGTACCGAAAAGGCCTTCAAATGCGAGATCTGTTCAATGCCGCTGGCCACCAAGCAGGATCTGTCGCTGCATATGCGTCACCACAAGAACGACAAGCGTTACAAGTGCGACAAGTGCAACAAGGCATTCGTTCGCAGCTCCGATTTGTCCATCCACGTCCGGATTCACACGGGTGAAAAGCCGTACAGCTGTGACATCTGCAGCAAGGCATTCCGGGCGCGCCAGAATCTTGTAGTCCATCGACGCACTCATCTCGGCGACAAGCCCATTCAGTGTGAGCTGTGCGACAAGCGCTTCGCCAGAAAGATCGATATGCGGGTGCACATGCGCAGGCATACTGGGGAAAAGCCCTACCAATGTGATGCTTGCCTGCGCGGCTATTCCTCCCGAGTGAATCTGGCGCGTCACCAGGAGCGTGAGCACGACAAAGAGGAGGAAAAGAGCTCTGGATCTGGTTCTGCCAAAGCTGAGAAGAAAAAGTCGGAAAAGGAGCAGGCGAAGGTGCAGGAGAAGCAACCGCAACCCAAAGCCAAATCAGCGCCACGTCGTCCCCGACGTGAGAAGCTGCAGAAGAAGATCGCGGCCCAGGAGAAGCTACTGGACGATTTGAAGCGCAGCTTGGGCACATTGCCGGAAATACCCGAGGAAGAGTCATCATCTCAGATTAAGTTGGATGCCGGAAAAGTGCCAGCTGATGCCGGAGCAGGGCTTGCTCAAGTTCAAGTCACGGTGTCCATGCAGATGGAGCCCGCTTCCAGCcacgatgacgatgaggagATCACGCCGGAGAAAGAGAACGCACTGTCCAGCTCGACTGTGTCGACGACCGACAAGACAAAGGCAAATCGCAAGATCACCAGCTACTTCACAGTCGTGGGTCAGCAGGCGGAAATCTAA
Protein Sequence
MLKMTNVAGPVQTMKKNANGNDNDDSEESDIDMDEEEEEEEEEDDLPDDVVLQIDSEDEAELEAQRIRLVREEEEEAKAKITTTKQEAREAQVSNGRANGVVKKEVEEKFEIGTTKSGKAATKRKVRGKPVRRTSVSSQASSVGSVASSASAASLVAAQVLADEKARSFIYSCTQCSHHYADRVVLSRHFQKEHAEKPKRKRGRSKLVSPEEDTPAVSSPLNLRAEEISLLKPCAQLLMQGESLLQLCLACNSQFVDQQHFQEHLSQQHGYFKLLLVPKEEPSDLPPLAMVTIPGALALGKSNQQLQLPIPAPETPPPEQDAKEPATTTQSNGSVVASNDKEGLHMISAMVAEIAAERVKKTSSPKVSKMIIKLPTAATKRGRKRAKPEKTKRRDIAEMLPLQPVKSENNQPRSEQPHPMRIAEGPQETKKPEQDDNQQSLKEAAEDKRAVEIPQLLENADKHPLKNVALGDKSEKMAEDPQQPKEIEEPKLPEIKEPLPEIVEETQQPKGVKEPLQPGKLKKSQQPEKSNTGEQPKPTGTQEKEQQPSPQPNLNPSKRKRGRKEQKSPTPPTVPLEDKEIKEESETTERRMRKSRNLVDYVVEIKDEEDPDEGEEAELDEDCSETVSPNTSSTDDSFTSIKRESSEESQRNEPGGSIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGKAFRLKMRLVEHQLRHRTEKAFKCEICSMPLATKQDLSLHMRHHKNDKRYKCDKCNKAFVRSSDLSIHVRIHTGEKPYSCDICSKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYQCDACLRGYSSRVNLARHQEREHDKEEEKSSGSGSAKAEKKKSEKEQAKVQEKQPQPKAKSAPRRPRREKLQKKIAAQEKLLDDLKRSLGTLPEIPEEESSSQIKLDAGKVPADAGAGLAQVQVTVSMQMEPASSHDDDEEITPEKENALSSSTVSTTDKTKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00492416;
90% Identity
-
80% Identity
-