Basic Information

Insect: Drosophila truncata
Gene Symbol: zfh1
Assembly: GCA_008042515.1
Location: VNJQ01003364.1:7336-11588[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.3e-05 0.002 18.5 1.0 1 23 153 175 153 175 0.97

2 15 0.00072 0.063 13.8 1.2 3 23 183 203 181 203 0.94

3 15 0.00024 0.021 15.4 0.2 1 23 368 390 368 390 0.98

4 15 0.00012 0.01 16.3 0.8 1 23 396 418 396 418 0.98

5 15 1.2e-05 0.0011 19.4 2.3 1 23 450 472 450 472 0.97

6 15 0.0082 0.71 10.5 1.3 1 23 506 528 506 528 0.93

7 15 0.0094 0.82 10.3 1.3 1 23 534 557 534 557 0.97

8 15 0.023 2 9.1 0.4 3 19 566 582 565 583 0.95

9 15 0.00014 0.012 16.1 5.6 1 23 592 614 592 614 0.97

10 15 0.04 3.5 8.3 0.4 2 23 620 641 619 641 0.96

11 15 8e-06 0.00069 20.0 1.0 1 23 650 672 650 672 0.98

12 15 0.0009 0.079 13.5 0.1 3 23 680 700 678 700 0.97

13 15 4.8e-05 0.0042 17.5 0.5 1 23 706 728 706 729 0.95

14 15 0.032 2.8 8.6 0.3 1 23 739 761 739 761 0.97

15 15 0.0049 0.43 11.2 0.2 1 23 1297 1319 1297 1319 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.3e-05	0.002	18.5	1.0	1	23	153	175	153	175	0.97
2	15	0.00072	0.063	13.8	1.2	3	23	183	203	181	203	0.94
3	15	0.00024	0.021	15.4	0.2	1	23	368	390	368	390	0.98
4	15	0.00012	0.01	16.3	0.8	1	23	396	418	396	418	0.98
5	15	1.2e-05	0.0011	19.4	2.3	1	23	450	472	450	472	0.97
6	15	0.0082	0.71	10.5	1.3	1	23	506	528	506	528	0.93
7	15	0.0094	0.82	10.3	1.3	1	23	534	557	534	557	0.97
8	15	0.023	2	9.1	0.4	3	19	566	582	565	583	0.95
9	15	0.00014	0.012	16.1	5.6	1	23	592	614	592	614	0.97
10	15	0.04	3.5	8.3	0.4	2	23	620	641	619	641	0.96
11	15	8e-06	0.00069	20.0	1.0	1	23	650	672	650	672	0.98
12	15	0.0009	0.079	13.5	0.1	3	23	680	700	678	700	0.97
13	15	4.8e-05	0.0042	17.5	0.5	1	23	706	728	706	729	0.95
14	15	0.032	2.8	8.6	0.3	1	23	739	761	739	761	0.97
15	15	0.0049	0.43	11.2	0.2	1	23	1297	1319	1297	1319	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATTCAGTGGATACAGCACCATCCCGCTGCAGGCGACTCCTCCGAGACGGATATTTTGGAGCACGAAGACGCCGAGGGCGATGATATGGTGAGCGGCGCGGACGGTGACCCAGATGGGGACGGGGATGCAGATGCTGACCTGGACCATATGGCTGCCGAGAACCTGATCTTTATGGCGCGCGACGGCCACCTAGGCGAGATTATAGCCGCCAACGAGGGCACTGTCCTGGTTACCGCCGATGGCACTACGGTGGCCTATGCGGAATCCTTTGATGACGACGCCCAGGTGGTCACCGAGGAGGTCATCACCGACGATTGGGTGCAGCACCAAGGAGCTGAGCGCGTTGAAATCGCAGCTGAGCAGATAGCTGGCATTAGTAGCTCTCAGGAACTTTTGGACATGGAGCAGGATGAGTACACGGCACTGCGACCCTATCCCTGCGACTTTTGCAGCAGACGCTTTCGGAAGAAGGCCAGCTTAAACAATCACATGCTTGCCCACCAAAATGATCGACCTCATCTCTGCAAGCTGTGCGGAGCACGCTTCTCACGCAGGGCGGAGCTCATTAGCCATTTTAAGGCCCACGCTGAAGCCCAGGATGCTGCGGATGCCGAggcagccgccgccgttgccgttTCCTCTtcttccatcaaatttgagaatcAGGGCCACAGGCAGTTTGATGATCACTACTACGAGCAGGAATGGCCGCTgtatcagcagcaacagcagcagcaggaacaggatcAGGAACAAGTGCTAGTGCAACATGAACAGATGCTGCAACAGGAACAACAGCAATTAGTCTGCAACAGCGAGGTCCAGTTTGTGGCCAGCTACACAACATCggtggctcctcctcctgctccgtCGCGTGGAAGAATTAGCAGGCTGAAGCCCAAAGAGGAGAGCAGCCAGTTTATCGTAATTACCGATAAGCCAACGCCCAATGAGTTGAGGGATTACATGGCCAGTGAGCCGGTGCCTCAGCCAGAGATGTCCACGCCGCAACCCATGGCTATTGATCCGCCGCCAGCGCCGCAGCCAAACTTCCCGGTCCTGGACGACAGCAAGCCCTTTGTGTGTCAGCAATGCGGATTGGCTTTTGCTAGGGAAAAGGCGCTAGTCTCGCACACAAAGAACCATCGCGTGGACTCGCCCTTCGAGTGCAATCAGTGCCAGGAGATGTTCTGGGATAACAGCAGCCTGCAGGATCACCAAAAGACGCATCAGTTTGAGGAGAGCAACTCGGAATATGATCCCGCCTCCGGCGATGATAGCGCCAGCGAAACGTCAGAGCCGGAGGAGCAGCTCTACGGAGAGTTTTACTGTAACGAGTGCGGCATCTCCTTCCATCGCCAGGATCTACTGCGGCGACATGCCAAGCAACATTTCAAGCAGCAGGATCAGCATTCAACGGTGGCCGCAACCGACGGTAGTTCCTCGGACGTCTTAGCCAGCGGGGATCAGGCCAAAGACGGTAACGGTGGGCACTGTTGTCAAACGTGCGGTAAATCATTTCCCAGTGCCTTGGAGATGCTTACCCATGCCGAAATCCATGCAAGGTTTCCGCCCTTCAAGTGCGTTCTTTGCGGCATAAGTTTCTACGAGGAGCAGGCCATCAAGAGGCACCTGCACACCCGCCATCCCAACGAACTGAAGGCCAACTCCTGTGTGCTGTGCGGCAAGGAGTGTCGCGATCGAAAGGCCCTGATCAAGCATGCCTGGGATCACTCCCGAGAAAAGTGTCACTCGTGCTCCAAGTGCGGCAAAAACTTTCACAACAAGGCGCGCCTGAAGCGACATATGGCCTCGCATCGAGACAAATCCGTTGTGTGCGAGGTCTGCCAGGAGGAGTTCCCAGATGGACGTACATTGTCCAATCACCGTCACTCGCACAGCACCACGTCACCGGGTAAACTGTTTCCCTGCCACGAATGCGGCAAGACATTCGGATCACGCAGTTCCCAACAAATACACGTGCGCATCCACACGGGTGAGCGTCCTTACGGCTGTCGCTATTGCTGGAAAGCGTTCGCCGATGGCGGTACGTTGCGTAAGCACGAACGGATTCATACGGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCGCGCGCCTTCAATCAGCGGGTGGTGCTGCGTGAGCACATTCGCTCCCACCACTCGGGGCTGGACGTGGCGAGAAATACCTACCACTGCACGGTCTGCTCCGAGGATCTGGCCTCTTCGAATGACCTTATACAGCACCTCATCCAGCACAGTGATTCGAACACCGCCAAGCAGCGTCAACCAGTGACGGGACCGCGAAAGTACAAGCGTCGACGCAAGCTGCAGCCTCACGAGATTGCGCATATGCGGGCGGAACACAAGGATGCCAACGGCGGAGGCGAAGAAGAGGAAATTCTTGGTGGCGAAGGCGATGGCGATGTCGATGGAGAAGAGTATGCTAGCGATATTGACCTTTGCGACTTTGATGTGGAGAATGTGGACGATTTGTTCGATATGGCCGAGTCATCGcccaaaaaagagaagcgCAAGAGGACATCGGCAGCGGCATCCGTAAAGACCGAATCTAAGCCAGTTTCCAATGGCGGAGCATCGTCGGCGAAGCCTGTCCAGGAGAAGAATAAGGCTAAGCTGCGATATGACTCAACCAGCAGTCAGCAATCGGATCGTATTTGGGAGGAGAAGTTCCTGCAGGATAGTCAGGTGGCGCTTTTCCAAATCGATTCGCTGGTGGTCGTCAACGACACTCATCTTCAGCCCGCAAGCTCAACGGCCATAGGCAAGACGAGAGGTGgcgccaagcagcagcagcagcatcaggcgAAGCAGTCTGGCAACTCCAATCCCTCAGCTGCAAGCTCAGTTGCTACATCATCGGCTTCCGCCTCCACTTCTAGCAGTCGCAGCAGAAAGAAGACTGCAGCCGTAAAGACGCCGGCTGCCTCGCGACCCCGAATGATTCACACGGAAAAGGCCAAGGTGCCGTCTAGAGGAAATGCTGGCGGAGAACTGGCGAAGAAGACACGCTCCAAGACCTACATCACCCGCACGGAGACGAGCAATCTGAGCAGTCTGGAAAAATCGCGCAGCCGAGCCTCCAACATTGTGGATGATTACGAAATCATTTCACCGGCTACCCATCCTCCCAACCAGATCAGTTCCAGTCCCCTGCACatcaagcaggagcaggagcagcagcatcgggGTCAGATGATGTACGACGACAATCTCCTGATAGACGCTGCCCTGCTGCGGGAGAAGACCTACGAAAAGTTCAATCCGAGCATTGTGAACGATCTGGAGGATATCCTGCGCTCACCGCTCAAGCACGAACGCAATACCCGCCTGCGATTCACCAGTGAATCCTCGACCACGCCACAGTTTCTACCTGAAGAAGAGCAGAATCTGATTAAGATCGAACCCACGTCTCCGGATTTGCGGGAAATGGTGGAGAGTCAGAGTCAAAGGGTCAGGGTTCCAAGTGGCAACACACCGTCGCCCTCGTCTTTCTCCGCCGCCAGAACTTCTCGTCATCGTATGATCACTGCCAGTGGACCAAGGACAGGAAACAAGAGATccgcaggaggaggagaaagtGGTAGCAGCGCTAGCAAATCCTCATCTGCCCCAGGAGTGGAGGCCAAGAAAGTGAGCACTGCTGCCAGCAAGGTTGGCAGCTCGTCCTCGTACCTCAATTACGGGGTGGATGCCTACAATGTGAACGTACCTGCCAGTGCCAGCACTGCCGATGTGGGCAGCGGATTTTTCTCCATCTCTGAGGTCGTGTCGGCCGCCGATGCTGCTGATGCGGCGGCTAAGGCGGCGGCAGCCGGGAAACCGGAGCGGAAAACTCGCAGTTTCGAGTGCGAAATGTGCTCGGCCATTTTTTATGATCGAGCTCAGTTACTGGACCATGTGCACATTCACATCTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDILEHEDAEGDDMVSGADGDPDGDGDADADLDHMAAENLIFMARDGHLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAVAVSSSSIKFENQGHRQFDDHYYEQEWPLYQQQQQQQEQDQEQVLVQHEQMLQQEQQQLVCNSEVQFVASYTTSVAPPPAPSRGRISRLKPKEESSQFIVITDKPTPNELRDYMASEPVPQPEMSTPQPMAIDPPPAPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETSEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDQHSTVAATDGSSSDVLASGDQAKDGNGGHCCQTCGKSFPSALEMLTHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDANGGGEEEEILGGEGDGDVDGEEYASDIDLCDFDVENVDDLFDMAESSPKKEKRKRTSAAASVKTESKPVSNGGASSAKPVQEKNKAKLRYDSTSSQQSDRIWEEKFLQDSQVALFQIDSLVVVNDTHLQPASSTAIGKTRGGAKQQQQHQAKQSGNSNPSAASSVATSSASASTSSSRSRKKTAAVKTPAASRPRMIHTEKAKVPSRGNAGGELAKKTRSKTYITRTETSNLSSLEKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRGQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEDILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQSQRVRVPSGNTPSPSSFSAARTSRHRMITASGPRTGNKRSAGGGESGSSASKSSSAPGVEAKKVSTAASKVGSSSSYLNYGVDAYNVNVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -