Basic Information

Insect: Drosophila tropicalis
Gene Symbol: -
Assembly: GCA_018151085.1
Location: JAECWH010000555.1:1580947-1591737[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00062 0.048 14.2 2.0 1 23 804 826 804 826 0.98

2 8 0.0001 0.0081 16.6 1.4 1 23 858 880 858 880 0.97

3 8 0.15 11 6.7 0.4 1 19 888 905 888 911 0.81

4 8 0.026 2 9.1 0.0 3 23 918 939 917 939 0.96

5 8 0.0002 0.016 15.7 3.5 1 23 945 967 945 967 0.97

6 8 0.028 2.2 9.0 0.2 1 23 974 997 974 997 0.95

7 8 0.00026 0.02 15.4 2.2 2 20 1004 1022 1003 1025 0.91

8 8 0.052 4 8.1 8.7 1 23 1031 1054 1031 1054 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00062	0.048	14.2	2.0	1	23	804	826	804	826	0.98
2	8	0.0001	0.0081	16.6	1.4	1	23	858	880	858	880	0.97
3	8	0.15	11	6.7	0.4	1	19	888	905	888	911	0.81
4	8	0.026	2	9.1	0.0	3	23	918	939	917	939	0.96
5	8	0.0002	0.016	15.7	3.5	1	23	945	967	945	967	0.97
6	8	0.028	2.2	9.0	0.2	1	23	974	997	974	997	0.95
7	8	0.00026	0.02	15.4	2.2	2	20	1004	1022	1003	1025	0.91
8	8	0.052	4	8.1	8.7	1	23	1031	1054	1031	1054	0.96

Sequence Information

Coding Sequence: ATGGGATCGCGGATCATGCATATGAGAATTCACAAACTTATCATTGATTCGCACTTTCCCTCTGAGAATATGGATTCGGACATGTTGATCAAGGTGGAGCCCAGAGTAGAGGTGGATCAGTCACTAAATCTACTGGACAGCCTCAATACGGCATTGCGGTGCGATGCTATACAATTTTTGCTGCAGACGCTTAGGTGCAAATATCCAGAGGCCTGCGACCAAGTCGTTAGGAATCTCTTCAGTCACATAATAAAGGATAATGGATCGGGAGGAAAACTGGAGGGAGGAGGTGGGTCAGGTGGAGGAGATGTGGCGGAGCTAGCGAAGAGTCAGCAACTTCAGCTGTTGTTGGCCACGAAAAAAGAAATGAAGATGGAGCCGACGGCAACAGAGATAAAGCGTGAGAGTAATGCTGAAACGACAGCTGGCTCAACAACGGATTTAAATCAAAATTTTGAGAAAATTCTTTGCAAGGAGGAATTTATGTGCCTCGATGAGGAGGAGGAAGAGGAATTCAATGATGATAACGATACGGAAAATTCATCATCCCAGCAATATCCTGCTCGTCGGAACAACAACAATAACAATGTGGATGCTATTGGTCCTGGTGATCCTCTCGATCTGATACAAACGAATGCAAGTGGCGGCGGATCTGTATTGGTGAAGAGAAAATATGCGGCCAGTTTTGGTAATCCTGATGAGTTGAAACACGACCAGGAACAGGAGGAGATCGATGGCAAATTAATGATTAAAAGAAAACGCATTAATCACGTGGCTGTGGCTAGTACTCTGGCCACCGCCACATCGCTGAAGCGAAGGTTAGACAATCGTCTGGGCGTGGGTGTGGGCGAGGGCTATGTAATTCAGGAGGATAACCAGTACACGATAAGGTATCATCACAGCTCAGGGCAGTTCAGTGAGCGGGCCTTTAAGGCCCAGTTTCGAGAATTGTTGAGATTGGCGCTGAGTCAGCACCACAAACCCTTCCTCAAGCAGTTCTACGAGAATTTTGTCATCAATGGACGATTGCTGGGTACCACTCCGTCGACGAAGATACTGAAAGCGTTGCGTGAGGAGCGATTGGAAGAGTGGAGGAGGCAGAGGGAACAGCGGACGCTCTTGGTGAGCTTATTAAAACAAGAACGAGAGCTGGACACGGAACGTGTCCAGATGCAGGAACATGAGCAGGAACAGGAGCAAGAGCTAGAGCAGGAACAGGATGAGCAAAAGCAGGAGCTGCATTTGCCAACCATCTCGTTTGGTGATTCCGAATTGGAATCGGAGACTGAGTCGCAATTATCTTCGGCCGCCCAAGAGATTATGAAATTCGAGGAGTTTATTGACGAGGGCGTAGGCGCTGGACGTCTAATTGATGGCCTGGAAATGGAGCCGGAGATTGATGAAATGCTAATAACTGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTAAACCATGATAATGGACATCATATGAACAGCAGTGCAAATCTTGTGATTAATGGCCTTACATCAAGCAATAGCAACAACAATGGTCAGCAGCTAGCCCTGTCGGATGAGCACCAGCAGCCAGTTAGCAAGCCATTGTCATCGCATCATCATCCGCATTCTCTCCAGTTACCTAACCCCTCGATGGAAAACCATGTGATGAAAGGAACTCAACCCCCGCCACCAGGGCATAATATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTTTCTCCCATGATGAACAATCGCCAATTGCCATCATTGGCTGCCTTGTCGAACCTGAGTGGAGCTGGAGGAAATCCTCAACATCCCCCTCATCCACACCCGCTTTCGCACTCGCATCCCCATCCCCATTCGCATCCGCATCCACACGCTGGCATGCCCTCAAATGCCAGTCAGTTAAACTCCTCTTTGGATTTAGATGACAATGAGTTATCTCCCGACGAGGATGATGATGACTTGGACCAAGAGTTAGACGAGTTGGAGGCAGCTAAACAACAATTAATCGATGGCGGCAGTAGCAGTAGCACATCACTTCAAGCTCCACCTTCGCAGCAGGGTAGTGCGGGAAGCGGCGGGGCTGGTGGTAGTCACACGCCTGGCATTAAAAAGGATAAGCCCAGCTATAATTGCCTATTGTGCCCGAAATCTTATCGCAAAAGGAAATCCCTGTTGGATCATTATAAAATGCATCCAGGCTATTGTCACGATTGTGGACAGCCAAATGGGAATACGCTAGAGGAAATCATTCAGCACAATCGCACGATGCATGTGAAGGAGTTCCCATTTGTGTGTGAGACCTGTGGCGAGTCCTATTCGCGAAAGCAACAGTTCCATGCCCACGTCGAGTCCCATAACAAGAAGGAATTCAAAACCTTTCCTTGCGGTGAATGCGGCTTAAAGTTTCCTCAAAAGAAGTTACAACAACATTTCGAGGAGACCGGTCATAAGGCCGATGGGGCCATCTGTGAGGTGTGCGGCGACGAGTTTCCATCAAAGAATGCCCTCTACCAGCATATCATTCGTGTCCACAAGCGGGATAATTTCTTTGAATGCCACATTTGCCATAATCGTTTCACCCTCAAGGCCAATCTGGAGCGTCATGTCCAGCTGCATACGGAAGTGAAGCGCACATATGTATGCGATCTATGCGGCTCCTCGTATTTCACATATCCCGCACTCAAGGAGCATTACAGCAATGCCCACGTGGATGTCTCCGAATGCAAGTGTACGCTTTGTGGCAAGCGTTTTGGTTCAGCCAAATCACTGCAGAGGCATTTGCCATCCCACTCCGAAGAGAGGCCACATTGTTGCAACTACTGCGATCAGACCTTTAAATGGAAAACGCATTTGGTGCGTCACAAGCAGACAATGCATGGCAATCAACCGCCACCGCCCAAAAAGGCCAAGCAGCGCTTTCCCAAGACCAATGAAGAAGCTGAATTGGCTGCCTTGACAGATATGCCGGGACCGCCACCTGTCAAAGCCACTAAAAAGTCTAATGCCAGCAAGACCAAAACCCAGACAGGAGCTGGAGTTGAACTTAAGGATAATAAATTCTATATAGTCGACTCGGCTGAATTTCTAGGGCTTCCAATGAATGTGCCCGCTGCCCAGCAGCAGCAGCAACAGCAACCTGTAGTCAAACCCCAGCCACCACAACAACAACAGCAACCACCCCAACAACAAGATCCAGCTCTGGCTGGTGATCTATTGAGCTTCCAGCATATGTGGCCGGCGCAAGGCTTTAATCAGGCCGCACCTCAACAGCCACATCAACCGCATCAACCGCAGCAACCCCAGCAGCAACAGCCTCAGGCCCAACCCAATCCGAGTGATCCACATAATTACAATAATATAGGCAGCATACTCACGAATCTCATTGACACAAATCCACAGCCAATGGAATACAATTTTGATTTAATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGATGCGAGCGGGTCCTGTCTACGGAGGATCACCGGCAGTGGCCTATGAACAACATTTGGGCGATCAATTGCAGGTGGCCTCTGAGCAACAGAAGCAAAATAGCTTCCAGCCATATCATTCCCATGGATTGCAGCCTCCACCGCAGCAGCAGCCACAACAACAAGCAATGCATCCCCATCTGTTGCCACCACCAGGACCTCATGGAAGTCTCTATGAGCGAACCGGGGGAGTTGGTGTGGGCGTGGGTGTAATAGGCGTTGGCGGCTATCCAATGCTCGGTGATGAATCCAAGCCCATCCTGCCACCTATGATGGGTGGAATGATGCAGCAAATTCCCCATGGGCAGCCGGATTTATTGTACTATCCAGTGAAGAACGATTGA
Protein Sequence: MGSRIMHMRIHKLIIDSHFPSENMDSDMLIKVEPRVEVDQSLNLLDSLNTALRCDAIQFLLQTLRCKYPEACDQVVRNLFSHIIKDNGSGGKLEGGGGSGGGDVAELAKSQQLQLLLATKKEMKMEPTATEIKRESNAETTAGSTTDLNQNFEKILCKEEFMCLDEEEEEEFNDDNDTENSSSQQYPARRNNNNNNVDAIGPGDPLDLIQTNASGGGSVLVKRKYAASFGNPDELKHDQEQEEIDGKLMIKRKRINHVAVASTLATATSLKRRLDNRLGVGVGEGYVIQEDNQYTIRYHHSSGQFSERAFKAQFRELLRLALSQHHKPFLKQFYENFVINGRLLGTTPSTKILKALREERLEEWRRQREQRTLLVSLLKQERELDTERVQMQEHEQEQEQELEQEQDEQKQELHLPTISFGDSELESETESQLSSAAQEIMKFEEFIDEGVGAGRLIDGLEMEPEIDEMLITGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNHDNGHHMNSSANLVINGLTSSNSNNNGQQLALSDEHQQPVSKPLSSHHHPHSLQLPNPSMENHVMKGTQPPPPGHNIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSPMMNNRQLPSLAALSNLSGAGGNPQHPPHPHPLSHSHPHPHSHPHPHAGMPSNASQLNSSLDLDDNELSPDEDDDDLDQELDELEAAKQQLIDGGSSSSTSLQAPPSQQGSAGSGGAGGSHTPGIKKDKPSYNCLLCPKSYRKRKSLLDHYKMHPGYCHDCGQPNGNTLEEIIQHNRTMHVKEFPFVCETCGESYSRKQQFHAHVESHNKKEFKTFPCGECGLKFPQKKLQQHFEETGHKADGAICEVCGDEFPSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRTYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTFKWKTHLVRHKQTMHGNQPPPPKKAKQRFPKTNEEAELAALTDMPGPPPVKATKKSNASKTKTQTGAGVELKDNKFYIVDSAEFLGLPMNVPAAQQQQQQQPVVKPQPPQQQQQPPQQQDPALAGDLLSFQHMWPAQGFNQAAPQQPHQPHQPQQPQQQQPQAQPNPSDPHNYNNIGSILTNLIDTNPQPMEYNFDLMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRAGPVYGGSPAVAYEQHLGDQLQVASEQQKQNSFQPYHSHGLQPPPQQQPQQQAMHPHLLPPPGPHGSLYERTGGVGVGVGVIGVGGYPMLGDESKPILPPMMGGMMQQIPHGQPDLLYYPVKND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523971;
90% Identity: -
80% Identity: -