Basic Information

Insect: Drosophila tropicalis
Gene Symbol: BCL11B
Assembly: GCA_018151085.1
Location: JAECWH010000150.1:7466473-7481722[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.023 1.8 9.2 2.4 1 23 297 320 297 320 0.95

2 6 1.2e-06 9.5e-05 22.7 1.5 1 23 753 775 753 775 0.98

3 6 0.011 0.83 10.3 4.7 1 23 781 803 781 803 0.99

4 6 1e-06 7.7e-05 23.0 3.2 2 23 1068 1089 1067 1089 0.97

5 6 1.3e-05 0.001 19.5 3.3 1 23 1095 1117 1095 1117 0.99

6 6 2.4e-05 0.0019 18.6 0.4 1 22 1125 1146 1125 1146 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.023	1.8	9.2	2.4	1	23	297	320	297	320	0.95
2	6	1.2e-06	9.5e-05	22.7	1.5	1	23	753	775	753	775	0.98
3	6	0.011	0.83	10.3	4.7	1	23	781	803	781	803	0.99
4	6	1e-06	7.7e-05	23.0	3.2	2	23	1068	1089	1067	1089	0.97
5	6	1.3e-05	0.001	19.5	3.3	1	23	1095	1117	1095	1117	0.99
6	6	2.4e-05	0.0019	18.6	0.4	1	22	1125	1146	1125	1146	0.97

Sequence Information

Coding Sequence: ATGTATAACAAAATGCTGTCGATCAGTGAAGATCATGGATTCCGTTCGCTGAGTCATTCCGACTCCACAGTGAACGATGCCGTGGCCGCACAGGACATACTCACGTGCGGTGCCTGCCAAAAGACTTTCGCCCTCTCCGACATTGTCAAGTTCATCCAGCACAAGGTGCTGCAGTGCAACAAAGAGAACTATGGCCAATGCACGACACAGGGTCCAACCATGGATCGTGATGCCGAAGAAGGACGTCCCTTGAGTTTGGTCAATCGACGACCCTCCATATCGGCGCCCATCACAGGCCGCAAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCATCCAGGATACACACACCGCCACCCAGTCCGGCTGATCTGTTGGCCGATGGAGCCAGCAGTACACCCAAACGTCTCGTAGATGAGAATGACAATACGACACCAAAAGACAGTGAAGCCGCCGCCGCCGCCGGCGCTGGCGTCACTTTAGAATCCACCACAGTTAGTGGCAACAGTCCAAAAAGTTGTACCACCAGCAACCATCCAGTAAATAAGGCAGACAGCAGGGACAGCAGTTGTGAGCTGGATGATGAGGATGATGAAGATGATGATATGGACACAGATAGGGCCACCAAGGTTAAGGAGGAGCCATTCGGCGACGATGATGACGATGAGGTGAATGCGGCCGATGAGCGGGTTCATTCGGTTGGATTGGATTGCCCACCACTGGCCAAGCGACCCAAAATGGAGCTTGTCGATGCTGAAGCCAATACAGTGCATACAGAGCCCAGCAACTACACCTGCTCCACATGCAAGACCCGCTACACATCCGCCTGGCGTCTGATCCAACATGTCCAGCACTCGCATGGCGTGAAAATCTATGTGGAGGCCACTGGAGGAGCCACATTGACGGTGGCCACACCGGCCAGCCTCAATAGCAATGCATTGGCTGTGGCCGCCGCCGCTGCTGCAGCAGCTGCCGCCGCGGCTGCCGAATCCCCCACAAGGAGTTGCAGTCCCGTCCCAGTTAATCCTGTGTCAGCGGCAGCAGCCGTGGCAGCCCAATCCCTGCATTCCCTCAAGCGTAGCAGTCCGGCGGCATTGTGTTCCAGCTCCTCACTGTCTTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCCATTGTTGCCCCCACCAGAGGCCATGCATGCCAATCCCTTCCAGCTGCTGCGTATGCCATTGCCGCCGGCATTGGCCCAAGGTAATGTAGTTCCTAGTGTGTCGCCTCTGTTCGGTCGTCCGACGCCAGCGGATCACTATCGCATGGAGCAGCTGGTTACCGAGCAGTTCCGTCATCATGGCTTCAATTTGGCAGCAGCCGCTGCTGCCGCCCAGGCCCAGTTCAATGCAAATGGCAATGTCAATGTCAATGTTCCTAATCCCGCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACACCGGGTCTAGCCGGAGCCGGTGGCAATGCATTGAAATTGGAATCACAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCCCGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCCCGAGAAGGCCAGTGAGACGGGCTCGGAGAATGGGGGTCTGGGTACACCGAGATCGGCCAGCACACCGCCATCGAAGCCCGGATCGGGTAACGATCAGGCCAGCTGTTATGCCTGTAGCTATTGCGACAAGAAGTTCCGTTTCGAAAACAATCTGATCATCCATCAGCGGACGCACACTGGCGAGAAGCCGTACAAGTGCACGGCCTGTGACTTTGAGTGCTCGCACATACAGAAGCTGATGAAGCACATGCGTGTCCATCGCAGTCCCGCCGAAAGCCAAGATGGCCAGGATGGTCCCGACAATCAGGACGGCGGCAGCAATGCCGACTCCCTGGAAACGAACGAGGCCGATCACGATGAGGATCCCAACCCTGAGGAGTCCGAAGAGGATGAGGATGCCGATGGTGATGTGGATGCCGATGCAGATCTGGATGAGGACGATGACGAAGAGCTCGAAGATTGCGACGATATGAAATACGAGGCCGAAGACCTGAGTGTCAACAATCGCATCGATGGCAAGAGCCAGAGCCCCAAGACCACCAGCTCGGGTGCCACCTCGCTGGTGGGTGAGCTGATGGATAAATTTGGTTTGTCCAACATTGCCCAGTACAGTGAGGCCTATAAGCAGGCTCTGCAAGAGTCCGGCCGTAAGGATGCCTCTGCCGTGGCAGCTGCAGCCGCCGCTGCAGCCGTCGCTGCGGACAACAATAATCGTGTGTCGGGATCAGGTTCCGTTGCTGGATCAACACCAAATGGCCTGCCCGCGGCGGCGCTTCGTCTGCGGGATGAGTTCGCCAAGAACTGCAATATGTTCCAGCAACCGCAGGAGGCTACCGGACCAGCTCAGGTGCCGCTTTTCAATCCCTTCTCCAATCCCTTCGAGCTGTCCAAGCGCATGAAAATGGATGGCGGCGATTGGTGGGGCATGTCGGCTCTCCATCGCAACGAGACCCTCTTCGAGAACCTCAAGCTAAAGCCCCTGGGTCTGGGAGGGGCCAACTCATTGCTGCAGGGCCCCCTGCTGAAGAAGGAGAGTCGCCAGCGGAACGACACTTGCGAATTCTGCGGCAAGGTCTTCAAGAATTGCTCCAACCTGACGGTCCATCGACGCAGTCACACTGGTGAGAAGCCCTACAAGTGTGAGCTTTGCTCCTATGCCTGCGCCCAGAGCTCCAAGCTGACCCGCCACATGAAGACCCACGGACGGACGGGCAAGGATGTGTATCGCTGCCGGTTCTGCGATATGCCATTCAGTGTGCCCTCCACTCTGGAGAAGCATATGCGGAAATGTGTGGTCAATCAGGGTAAGGCGGCGGCGGCAAATGCTGTGGCGGCGGCCCAAGCAGCCCAGGCGGCTGCCCAACAGATTCAGGCGGCGGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCAAGCTCAGCTCTCACCCCCCTGCCCGCCCATGGGCGTCGGCTATCCACCGCAATTTGTGGCCGGACTCTCGCTGCCCGGCAGTGTGAGCGGTGACAATGACTCGAATGCCTCGTCCAGCCTGAATGCCCATCCCATATCGCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTVNDAVAAQDILTCGACQKTFALSDIVKFIQHKVLQCNKENYGQCTTQGPTMDRDAEEGRPLSLVNRRPSISAPITGRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSEAAAAAGAGVTLESTTVSGNSPKSCTTSNHPVNKADSRDSSCELDDEDDEDDDMDTDRATKVKEEPFGDDDDDEVNAADERVHSVGLDCPPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEATGGATLTVATPASLNSNALAVAAAAAAAAAAAAAESPTRSCSPVPVNPVSAAAAVAAQSLHSLKRSSPAALCSSSSLSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLLPPPEAMHANPFQLLRMPLPPALAQGNVVPSVSPLFGRPTPADHYRMEQLVTEQFRHHGFNLAAAAAAAQAQFNANGNVNVNVPNPAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPGLAGAGGNALKLESQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPEKASETGSENGGLGTPRSASTPPSKPGSGNDQASCYACSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAESQDGQDGPDNQDGGSNADSLETNEADHDEDPNPEESEEDEDADGDVDADADLDEDDDEELEDCDDMKYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKDASAVAAAAAAAAVAADNNNRVSGSGSVAGSTPNGLPAAALRLRDEFAKNCNMFQQPQEATGPAQVPLFNPFSNPFELSKRMKMDGGDWWGMSALHRNETLFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAANAVAAAQAAQAAAQQIQAAAXXXXXXXXXXXXXXXXXXXQAQLSPPCPPMGVGYPPQFVAGLSLPGSVSGDNDSNASSSLNAHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556079;
90% Identity: iTF_00571409;
80% Identity: -