Basic Information

Insect: Drosophila tropicalis
Gene Symbol: -
Assembly: GCA_018151085.1
Location: JAECWH010000574.1:4685423-4687274[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.31 24 5.7 0.2 2 23 384 406 383 406 0.93

2 7 0.00012 0.0092 16.4 0.5 1 23 413 436 413 436 0.97

3 7 8.8e-08 6.8e-06 26.3 1.9 1 23 441 463 441 463 0.98

4 7 3.9e-06 0.0003 21.1 0.8 1 23 469 492 469 492 0.91

5 7 0.00083 0.064 13.8 2.1 1 23 498 520 498 520 0.99

6 7 6.3e-05 0.0048 17.3 4.3 3 23 528 548 527 548 0.97

7 7 0.00058 0.045 14.3 0.7 1 23 554 577 554 577 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.31	24	5.7	0.2	2	23	384	406	383	406	0.93
2	7	0.00012	0.0092	16.4	0.5	1	23	413	436	413	436	0.97
3	7	8.8e-08	6.8e-06	26.3	1.9	1	23	441	463	441	463	0.98
4	7	3.9e-06	0.0003	21.1	0.8	1	23	469	492	469	492	0.91
5	7	0.00083	0.064	13.8	2.1	1	23	498	520	498	520	0.99
6	7	6.3e-05	0.0048	17.3	4.3	3	23	528	548	527	548	0.97
7	7	0.00058	0.045	14.3	0.7	1	23	554	577	554	577	0.97

Sequence Information

Coding Sequence: ATGGAAACTTGCGGCTATATTTGCGCTAGCAAGGACTATGAGAATTTCTATATGCGTTGTTCCCTCTGTTCCATTGACTTGGAGGCGTCAAGATGGCAGGAGTTTGTCTCGCATTTCCGAAACCTTCATATCGTGGTGGAATCGCCTCCATCTGAACCAGAAATTGAATCTAAAACGGAGGACCAGGATGCTCCTGTAAATGAAATTCATGTGGAGGTGGTTAGTTTGGAGGAAATTAATGAACTTGAGGAATTAATGAACGAGAATGTTACCTATGCAAATTTGATTGAGACAGATGAAGAAGAGGAGCAAATTCAGGTTGTCGAAATAGACGAACCAAAACAGGAGGAAGACGATGTAAGTGAATTGGAATTTGAGTCAATAGCTGAGGAAGACGAAGAAGAGGATGATGACGAGGATGGCGACTATGAACCAGATGCCGACGCCGATGCCAATCCTGTAACAGATAACTCTCCATTATACAAGTTCAATCCGTCATTCTTTCGCCGTGATCCACGTACTTTGACATTTATTGAGTTATATGAAGCGCATCCGTGTCTTTGGGACTCCGCCCACTCTGACTACAAAGAGACAAGTGTCTGTAAAGTGGCCTACCAGGAAATGATTCGAGACTTGAAGGAAAAGGCGTCTATTATTCTTACTGAACATTCCCTGATTGCAGCCATTAAGAAGCTACACCTGCAGTATAATACAGTGGAGAGGAGAGTACTTTGTGGCCAGATTAAAGACAATTCAGTGGCCTATACCCATTATACCAGTTGCGCCTATCTCAAAGCTAGCATGGATCAGCTAGAAGAGCAGAGAAACGGAAAGATACAGCTCGAATTTTTACAAAAAAATAGACTGACCACAGAACTGATTGATCTTTATGCCGGATTTCCGCAATTATACGATCCCCAGCATAGTGAATTCTCGAATATGAACTCTCGAAAACAAGCCTATGAAAGCATGGCCAACGATTTGACGGTGCCGGAGAATTTGGATATTAATTGCGATGATATCTTTCGGGCGATTCAATGTCTACGAAAATGGTATTATAAGCGTACTAAACAACCCATCAATGCGTCCGAAAAGTTCTATCAGGGCCTGTGCTCTTTCCTGCCGCCGAAACAATTCAAACAGCGATTAGTGTGCGAGATTTGTCAGCATGTCACCTACTCGGATAATGTTCTGCAGGCGCATATTTTTAAGGTGCACAATATTGGTGAATTGCCCTTTAAATGTCAGTTGTGTGATCGAAGTTTCATGGGACGAGGCGAACTAGCTACCCATGTCAAGAGATCCCACATTGGCAAGACACACGAGTGCTCATACTGTGATCGGACTTTTGCTGTACAATCTGATCTGAAGCTTCATATGCGGACACATACCAACACGAAACCTTATATTTGTGAGCATTGTGGCAAAGCTTTTCGACTAAGATCTCAACTAAAGCAGCATGTTACGGCAATTCATACCAAAATTAGGGCTTTCAAGTGTACCATGTGTCCAAAGGACTTTCTCAAGAAGGTTCATCTGGTGGATCACATTAAGAGTCATTTGAATATACGCGATAAGATCTGTACCACCTGTGGCAAAGGTTTCACAAGTTGTCATTCGCTCATTCGACACCGACAAATCCATGCGGAAGTCAAGAAATTTGCATGCAAACTATGCGATTCCCGATTTGCCCAATTCGTTGGACTCAATTCGCACATGAAACGAACACACAACTTGTTACGAAACCCTAAAGCCGATGTAACTGCAGAAGATGGGGAAGATGTGGATATTGAGTAA
Protein Sequence: METCGYICASKDYENFYMRCSLCSIDLEASRWQEFVSHFRNLHIVVESPPSEPEIESKTEDQDAPVNEIHVEVVSLEEINELEELMNENVTYANLIETDEEEEQIQVVEIDEPKQEEDDVSELEFESIAEEDEEEDDDEDGDYEPDADADANPVTDNSPLYKFNPSFFRRDPRTLTFIELYEAHPCLWDSAHSDYKETSVCKVAYQEMIRDLKEKASIILTEHSLIAAIKKLHLQYNTVERRVLCGQIKDNSVAYTHYTSCAYLKASMDQLEEQRNGKIQLEFLQKNRLTTELIDLYAGFPQLYDPQHSEFSNMNSRKQAYESMANDLTVPENLDINCDDIFRAIQCLRKWYYKRTKQPINASEKFYQGLCSFLPPKQFKQRLVCEICQHVTYSDNVLQAHIFKVHNIGELPFKCQLCDRSFMGRGELATHVKRSHIGKTHECSYCDRTFAVQSDLKLHMRTHTNTKPYICEHCGKAFRLRSQLKQHVTAIHTKIRAFKCTMCPKDFLKKVHLVDHIKSHLNIRDKICTTCGKGFTSCHSLIRHRQIHAEVKKFACKLCDSRFAQFVGLNSHMKRTHNLLRNPKADVTAEDGEDVDIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503498; iTF_00571402; iTF_00523927; iTF_00618652; iTF_00555322; iTF_00604324;
90% Identity: iTF_00503498;
80% Identity: -