Basic Information

Insect: Drosophila tropicalis
Gene Symbol: -
Assembly: GCA_018151085.1
Location: JAECWH010000848.1:9389442-9391545[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00028 0.022 15.3 4.3 2 23 150 171 149 171 0.97

2 9 1.1e-06 8.4e-05 22.9 3.9 1 23 177 199 177 199 0.99

3 9 4.2e-07 3.2e-05 24.2 1.0 1 23 205 227 205 227 0.99

4 9 1.3e-05 0.001 19.4 2.5 1 23 292 314 292 314 0.99

5 9 2.3e-06 0.00018 21.8 1.5 1 23 320 342 320 342 0.98

6 9 5.2e-06 0.00041 20.7 5.2 1 23 348 370 348 370 0.99

7 9 1.1e-05 0.00086 19.7 1.2 3 23 529 549 527 549 0.98

8 9 1.9e-06 0.00014 22.1 0.6 1 23 555 577 555 577 0.99

9 9 1.2e-07 9.5e-06 25.8 2.2 1 23 583 605 583 605 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00028	0.022	15.3	4.3	2	23	150	171	149	171	0.97
2	9	1.1e-06	8.4e-05	22.9	3.9	1	23	177	199	177	199	0.99
3	9	4.2e-07	3.2e-05	24.2	1.0	1	23	205	227	205	227	0.99
4	9	1.3e-05	0.001	19.4	2.5	1	23	292	314	292	314	0.99
5	9	2.3e-06	0.00018	21.8	1.5	1	23	320	342	320	342	0.98
6	9	5.2e-06	0.00041	20.7	5.2	1	23	348	370	348	370	0.99
7	9	1.1e-05	0.00086	19.7	1.2	3	23	529	549	527	549	0.98
8	9	1.9e-06	0.00014	22.1	0.6	1	23	555	577	555	577	0.99
9	9	1.2e-07	9.5e-06	25.8	2.2	1	23	583	605	583	605	0.98

Sequence Information

Coding Sequence: ATGCATCTAAATCATGCCACTGCTGCATCGGCAGCCATGGCAGCTAATGCATATCAACACTATGCACCTGCCCAGTTAGCCACACATGGTGGTGGAGCAGGAAGCGGCGGCGGGGGCGGAGGAGGTAGTGGTGGAGGCGGCGGTGGAGGTTCTGCTGCTAATAGCCTGCAACAGTCTACCACATTAGCTAGTCTGCAGCAGACACCGTTTGCCCTGCATCAGTTGACCGCTGTCCAGGCCATTCAGCATCCCACCCACCAGGCCATGTTGCATCAGCAACATCCATTGGTACACCTGCTCGATATCTCAACAACGTCAGCGAATAGCGGAGGCATTGGGGGTCTTGGTGTTGGTAATCATGCGCCCATGTCGCCCATGAAACAGGAGGTAAAGAGCGTCATCAGCGAGGAGGACGCGTCGGCAATCGATGATCCGCGCAAGAAGAAGGAGTGCCACGTGTGCAAGAATAAGTTCCGCCAGTTGACCACATTACGCAATCACATGAAAATCCACACAGACGAGCGACCCTACAAATGCAAGCACTGTGATCGCTCCTTCCGCCAAATCTCGACGCTCACCAATCACGTCAAGATCCATACGGGCGAGAAGCCGTTCACCTGTAATATTTGCGCCAAGGATTTTCGCCAGCAAAGCACACTAATTAATCACATCAAGACGCACAAGGCGGCAGAGTCGAGTACGCCGACATCGCTCCTCAACTATCAGCCTCAACAGCCGTCCACTGCTACGGGCAAGCGCAAATCCTTGGCAAGTCAAATGCTTTACCAGCAGCATCAACAGCGCGTACTAATCTCAAAGACCCTATATTCGGGTAGCTACACCTCACCGCAGGCGGCGGAGTTGGTTAAACCATATCAATGTGGCGTCTGCAAGCGACGATTCCCTCAGCTAAGTACGCTGCATAATCACGAACGAACCCACATTGATCCCAAGCCCTACAAGTGTGAGACTTGCGAGAAATCCTTTAGCCAACTGGCCACGCTTACCAATCACAAGAAGATCCATACGGGCGATAAGCCATACACGTGTTCCTACTGTCACATGCAGTTCCGTCAGCAGAGCACCCTCACCAACCACGTGAAGACGCACACGCATCTGCATGCCAGTTCAGCATCCGGTTCCGGAGCACAACCGGGTGCCGGAGTTGGCCCAATTACAGTGAATCATACGATGTCCGCACCCTTGGCACCAGGCACACAACAGCTGACCGGAGGAGGATTGCTGCCCAATAATCTTAACCTGCACGGCACAACGCCCAATATAATCCAGTTGGATCATCATCCGCTTTTGCATTTCCTTGATGGCAGCACCACGGTTAGCTCAGTAGTGGCAGCAGCGGCAGCCAACACCAAATTGGAACAATTTCACAACTCTTCATCGCCGGGAGGAATGGGCATGGCATCGGGGACACCAGGAACGGCGGGTGTACCAGGTGGCGCTAATACAACCAAGCTGGAACAATTTCAGAACTCTTCACCCTCACCGAACACAAATAGCGGCGTAATGACTATGGTGGGCACCATTAGTATGCTGAAATGTGAGAATCCGGATAAACCGTTTGGCTGCAGTGTCTGTCGACGATTCTTCTCCCAGCAGAGCACACTGGTCAATCACATCAAGACGCATACGGGAGAAAAGCCATATAAATGCAAGATCTGTGATGTCAATTTCCGGCAAGTGGCCACGCTCAATAATCACATGAAGATCCATACGGGAGAGAAGCCATATAACTGTTCCTATTGCCCCAAACAGTTCCGGCAAAAGAGCACGCTACAGAATCATCTTAGGGTGCACACGTGTTAG
Protein Sequence: MHLNHATAASAAMAANAYQHYAPAQLATHGGGAGSGGGGGGGSGGGGGGGSAANSLQQSTTLASLQQTPFALHQLTAVQAIQHPTHQAMLHQQHPLVHLLDISTTSANSGGIGGLGVGNHAPMSPMKQEVKSVISEEDASAIDDPRKKKECHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDRSFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQQPSTATGKRKSLASQMLYQQHQQRVLISKTLYSGSYTSPQAAELVKPYQCGVCKRRFPQLSTLHNHERTHIDPKPYKCETCEKSFSQLATLTNHKKIHTGDKPYTCSYCHMQFRQQSTLTNHVKTHTHLHASSASGSGAQPGAGVGPITVNHTMSAPLAPGTQQLTGGGLLPNNLNLHGTTPNIIQLDHHPLLHFLDGSTTVSSVVAAAAANTKLEQFHNSSSPGGMGMASGTPGTAGVPGGANTTKLEQFQNSSPSPNTNSGVMTMVGTISMLKCENPDKPFGCSVCRRFFSQQSTLVNHIKTHTGEKPYKCKICDVNFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523846;
90% Identity: iTF_00591115;
80% Identity: -