Basic Information

Insect: Drosophila tristis
Gene Symbol: zfh2_2
Assembly: GCA_018150885.1
Location: JAECWT010000174.1:617997-633386[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.33 22 5.5 0.5 3 23 2 23 1 23 0.96

2 14 0.00011 0.0076 16.4 1.4 2 23 240 262 239 262 0.96

3 14 2.8e-05 0.0019 18.3 0.7 1 23 294 318 294 318 0.92

4 14 0.0079 0.53 10.6 0.1 1 21 410 430 410 431 0.95

5 14 2.4 1.6e+02 2.8 0.1 1 21 494 515 494 516 0.92

6 14 1.1 75 3.9 1.9 1 23 537 561 537 561 0.91

7 14 0.054 3.6 8.0 0.5 1 23 815 838 815 838 0.98

8 14 3.9 2.6e+02 2.1 0.1 3 23 953 975 951 975 0.81

9 14 0.041 2.7 8.4 0.9 2 21 1057 1076 1056 1080 0.89

10 14 5.6 3.7e+02 1.7 0.5 6 23 1100 1118 1100 1118 0.91

11 14 5.4e-05 0.0036 17.4 2.3 1 23 1131 1153 1131 1153 0.98

12 14 0.00077 0.051 13.8 1.9 2 23 1160 1182 1159 1182 0.94

13 14 0.00027 0.018 15.2 1.7 1 23 1723 1745 1723 1745 0.97

14 14 0.00096 0.064 13.5 1.4 1 23 1860 1882 1860 1882 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.33	22	5.5	0.5	3	23	2	23	1	23	0.96
2	14	0.00011	0.0076	16.4	1.4	2	23	240	262	239	262	0.96
3	14	2.8e-05	0.0019	18.3	0.7	1	23	294	318	294	318	0.92
4	14	0.0079	0.53	10.6	0.1	1	21	410	430	410	431	0.95
5	14	2.4	1.6e+02	2.8	0.1	1	21	494	515	494	516	0.92
6	14	1.1	75	3.9	1.9	1	23	537	561	537	561	0.91
7	14	0.054	3.6	8.0	0.5	1	23	815	838	815	838	0.98
8	14	3.9	2.6e+02	2.1	0.1	3	23	953	975	951	975	0.81
9	14	0.041	2.7	8.4	0.9	2	21	1057	1076	1056	1080	0.89
10	14	5.6	3.7e+02	1.7	0.5	6	23	1100	1118	1100	1118	0.91
11	14	5.4e-05	0.0036	17.4	2.3	1	23	1131	1153	1131	1153	0.98
12	14	0.00077	0.051	13.8	1.9	2	23	1160	1182	1159	1182	0.94
13	14	0.00027	0.018	15.2	1.7	1	23	1723	1745	1723	1745	0.97
14	14	0.00096	0.064	13.5	1.4	1	23	1860	1882	1860	1882	0.97

Sequence Information

Coding Sequence: ATGTGCTTTATATGCAAACTATCCTTCGGCAACGTGAAGTCATTTAGCCTGCATGCGAACACAGAGCACAGACTCAATCTGGAAGAGCTCGAGCAGCAGCTACTGAATCGCGAGTACTCCAGTGCCATTATCCAGCGTAATATGGATGAGAAGCCGCAGATATCCTTCCTGCAGCCCCTGGACATAAATGCCACTTGTGCTGTCGAGAAGCTCATACTGGCCCCCGATGCAAATTGTACTCCACTGGCTTCAGAGCCAGAGCCAGAGCTAGATCATCATGATCATTATGAGCCGGATCAAGATCGGAGTCAGGATAAAGGAGTAGCACAAGCGATGGAGCAAGACTCAGAGCATGATCAGGTTCAGGATCCGGATCCGGATCCGGATCAGGATCAGGATCAGGAATCGCCGCCTCCATCGCAACAGCATCTGGCTCTGGCTCAATCTCAATCTCAGGCCCTGCCTTTGTCGCAGCCTCAGCCACATCGCTCTCCTAACAGCAACAGTGGCAATCTTGCGATATCGCCCAGCTCCTCATCGGTGACCAGCGTAGGAAATGCGTCTGGTGCTGCTTCCAGCTTCACAATCGGCGCGTGTTCCGAACACATCAATGGGCGACCCCAAGGAATAGACTGTGCCCGCTGCGAAATGCTGCTAAACTCGGCTCGACTCAATAGCGGGGTCCAGATGTCCACCCGCAACTCGTGCAAGACGCTTAAATGTCCCCAATGCAATTGGCACTACAAATATCAGGAGACGCTGGAGATCCATATGCGTGAAAAGCATCCTGATGGGGAAAGCGCCTGTGGTTATTGCCTAGCAGGACAACAGCATCCTCGGCTGGCCCGTGGCGAGTCGTACTCATGCGGCTATAAGCCATACAGATGTGAGATATGCAACTACTCCACGACTACAAAGGGTAACCTCTCGATACATATGCAGTCTGACAAACACTTGAACAACATGCAGGAGCTGAATAGTTCCCAAAATATGGTTGCTGCTGCGGCGGCAGCGGCTGCGAGTGGGAAGTTGCTGCTGTCCAGCTCATCGCCACAAGGATCCGGTGCCGGCCAACAAACTGTGCTGGGCTCAAGCGGCAGCGCGAGCGCGAGCACCGCTATCATCTCTAACAGCGTTGGGGGCAATGCAGCTATGGTTGCGACGCCAACGCCTGGATGCACGGGGGTAGGAGGCGTGGCCAGCGGCAGCGTCAAACCGAAGCCCTCGTTTCGGTGCGACATCTGCAGCTACGAGACTTCCGTTGCCCGCAATCTGCGTATCCACATGACCATTAGCGCTACGGATCAGTTTTCATATTCCCCAAAGCCCATGAAGCATGGCCATGGAATGGGAATGGGCTTGGGGCTGGGGCTGGGGTTGGGAATGCCACAGGGAATCGGCCACTCAAATGAAGCATCTGGTGAATCGGGGAGCGATTCTCAACCACTGGCGAAGCCAGATATGTGGCCCACGGCGCTCTACAGTTGCCTAATCTGCGACTCCTTCAGCACAAACAATTTGGACGATCTTAACCAGCATCTGTTGGTGGATCGATCCCGACAGTCCTCGAGCGCATCCGCCGACATAATGGTCATACACAACAACAACTACATATGCCGGCTCTGCAACTACAAAACGAACCTAAAGGCCAACTTCCAGCTGCACAGTAAGACGGACAAGCACTTGCAAAAACTGAACTTTATAAACCACATAAGGGAGGGCGGAGCCCGCAATGAGTACAAACTGCAGTATCAGCCCCAGCTCAGTGCCAATGTGGTGCAACTGATGTGCAACTGTTGCGACTTTCACACCAATTCCATACAGAAGCTCTCCATGCACACCCAGCAAATGCGACATGACACGATGCGGATGATTTTCCAGCATTTGTTGTACATTACGCAGCAGAGTCGAATGCACAAGGAGTCGTCGCCGTGCACGGCATCTGAAGATGCCCAATGTCCTTGTCCGGACGAAGATCAACAATCGATGGCAATGGCAACGATCGAGAAGGTTCTCATTTGCCAGCTGTGCAGCTTTGCCGCCAAAAATCTGTATGAAATGGTTCAGCATGTGAAGGGCATAAGGCACATGCAGGTGGAGCAATTCATTTGTCTGCAGCGTCGTAGTGAGAACCAGGAGATGCCCGGACTGAGTGAGGTGTACAAAGTGACTGAACGGATCCGTGGTAGCGAAGATATCATTTTTGAAGCTGGGTTCAATATGGCAACAACCGCACCCGTTGGGGGATCATCGGAGCTTGGCTTTGCAGCAGCAACAGCTGGCTCGTCGGGGGCTGCCGCTGCAGCTGCAGATAGCAACATATTATCTCCAAAGTCCACCTCGAGTTGCTCGACATCGTGTGGCAAGAGTATCGGTCGCATCGCGTCTCCAAGCATGAATGACTTTAGTCTGAGTGCTTCAAACAGCATTCCCACCACGGTTTTCAAGTGCAATTTGTGCGAGTACTTTGTGCAATCGAAGAAGGACATGGCCAGCCATATTGAAACGGTGCACCCGGGGGCAGAGGGTGACGACTTCATGAGTATACCAACGAACACGGCGGCTCTGCAAGCCTTCCAAACCGCTGTTGCAGCCGCAGCCATAGCGGCGGTCCAACAACGCTGCAGTGCCATCAACATGCCTAGAGAAGCAGACACGGAAATGGATCCTTGCATAGACATTAAGCGTGAGCGTCTCGAAGAGCAGGACGATCCAATGACGGGCATAGAGGAAAGAAAACCAACAGCCAATATAGATGTGGATTCGCCAGGAGCTACGGCTACAGCTACAACTACAACAGAATCAAAAACAACAGCAACCGCAACAACAGCAGCAACAACAACACCTGGAGTGCAGTGTCCCCTTTGTTTAGAAAATGGCTTCCGGGAGAAATCATTGCTCGAGACCCATTTGACGAGCGTGCACAGCGTCACCAAAGATGGCCTCGCCAGGCTTTTGCAACTGGTCGACAGTAAGGCCTGGAGTGATTCCCCATCCCCATGCCCATCGGTAACCGCAACAACGAGGACAGCTTCCAATTGCCATTCGAAACCGGAAGACTGTGCGACAACCACGGGGAGTGTAAGTACCGAAGACTGTGTGTCGACTGTGTTCCCTGCTGCCGCAGCAACCAGCTCCACCGCAAGCTCGGCGGGAATGCAAGGACTCTCCTGCCAGCAATGTGAGGCCAGCTTCAAGCACGAGGAACAGCTGTTGCAGCATGCTCAGCAGACGCAACACTTTCCAGAGCAGAATGGAGAGTACATCTGCCTCGCGACCAGTCACATCAGCCGTCCCTGCTTTACGAGCTTCAGCACACTCTCGGCCATGATCAGCCACTTTAAGGACTCGCACATGAGTCTGGTTATCTCGGAGCGCCACGTCTACAAATATCGATGCAAGCAGTGCTCACTAGCATTCAAAACACAGGAGAAGCTTACCACGCATATGCTCTATCATACAATGCGCGACGCCACCAAGTGCTCCTTGTGCCAGCGCAATTTTCGTAGTACACAGGCCCTGCAGAGGCACATGGAGCAGACGCACTCCAACGATGGAGCGGGAGCTGGAGTCGCGGCTGGCATTACCAGTACCAATACCAATAGTCCTCGACCGCCGACACCAACACCAAGCTACGGCGAGATGGAAAAATTGTCATCGGGGGAACGAGATCCCTCGATTGCTAGTGAAGCAGGGCCCAAATCGAATAACACCTCAAGACGTTCACTGTCACCGCTGAGACTAGAGTTGCAATACTCTAAGGAGACGGCGCAACTGTCGCCCAGCCCCAGCCCGCACACGCTTGACACGAACCAAACCCAGCAGCAGCAGCACCACCAACACCTGGCCACACTGACTGCGGCGTTGCTCAAGCAGCAGCAACAGTGTCACCCAGATGCTGGCATTCTGTCGGCAGATCCTCTATCGTTGTCCGCTGCCGACTTTTCTCAGCAGCTGCAGGGCCTGCAGAATCTCCAAAACCTGCAGCACATGCAGCAGCAATTTAGTGCTGTTGCTGCCTCTTCGGGAATGCCTATTAACCCGGTGGACATGCTCAACCTCATGCAGTTCCATCATTTAATGTCTCTTAACTTCATGAATCTGGCCCCTCCACTCATATTTGGCGCGAATGCCGCCAGCGGCAGTACAGGCTCAACAGCCGCGGCCCAAAACAACGGCATGACCTCCGCTTCCTTATCAGCACCAGCTTCCCAAGCGGGCGAAATGCAGATTGGGAGCGGAGCAAGTAACTTGACGGGAGAATCCACCAACGCGAACAATCCCACGGCCCAGCACAGCATCAATAGTAACTCTCAGATGAACAACAACCAAAAGCGAGCTCGCACACGCATCACAGACGATCAGTTGAAAATACTGCGTGCCCATTTCGACATAAATAACTCGCCCAGCGAGGAGAGCATTATGGAAATGTCGCAGAAGGCGAATCTGCCAATGAAGGTGGTTAAGCACTGGTTCCGAAACACTCTGTTTAAAGAACGGCAACGCAACAAGGACTCACCCTACAACTTCAATAACCCACCGTCAACTACCCTAAACTTGGAGGAGTACGAGCGCACAGGCTCATCGCTTGCAGTTCACTGTCACAACCAGCAGCAACTGCAACAGCAACAGCACGCACAATCAAATAGCTTCGAAACCAAATCAGAGAGCGGAAGCTCTGATGTAATGTCGCGTCCACCAACTCCAAATAGTGTGGCTGCTAGCAATTTGTATGGCAGCATGAATGACCTGCTGAGCCATCAGCTAGAAAGCATGGGGAGCAACATGGGTCCACCGAAAAAACTGCAAATAGCTGGCAAAACATTCGACAAAGGCACGGCCACCGTCTCCAGCTCGGCAACAGCATGCAATCAGTTTGAGAGCAATTCCTCCAGCTCGTCAAATTCATCGTCGACGTCGGGAGGAAAACGGGCGAACAGAACACGTTTCACGGACTATCAAATTAAGGTCTTGCAGGAGTTCTTCGAGAACAATTCATATCCAAAGGACAGTGATCTAGAGTATTTAAGCAAGCTGCTGCTATTGTCACCCCGCGTCATAGTGGTGTGGTTTCAGAATGCCAGGCAGAAGCAACGCAAGATCTACGAAAATCAGCCAAATAACTCACTGTTCGAGAATGAAGAGACCAAGAAGCAAAACATTAACTATGCGTGCAAGAAGTGCAGTCTGGTGTTCCAGCGCTACTACGAGCTAATACGTCACCAGAAGAACCACTGCTTCAAGGAGGAGAACAACAAAAAGTCGGCTAAAGCTCAGATTGCTGCTGCGCAAATTGCCCAAAATCTAAGTTCTGAAGACTCGAACTCTTCCATGGATATACATCATGCTGGCATCTGTCCCCCGGGTCCTCTAGGTCCACAGACTGTTTCAGCCCCTGTGTCTATCGTAACCCCATCCGGGCACGCAGGGTCCCAGCCATTTGGTGCTTCGCCCTCGCCACAGCATATATTTAGCAAGTCGTCGTCACTCACTGACTTCAGCCCATCCACGACTCCAACGCCTCCCCAGCGGGAACGAAGCAATAGTTTGGATCAGCCGCAACGAACCGTATCGAAGTTTGACTGCGACAAATGTGAGCTGCAGTTCAGCCACCTGGAGCTATTGCGTGAACACCAAATGATGCATCTGATGAATCCAGCAGCACTCTTGGCCGCCGCCGGCCAACACCCCAATCCAGAGGCGAGCTATGGTCCTTTCGGTAGCATACTGCAAAGTCTGCAGCATGCAGCGGCTCAACAGCAACAGCATCAACAGCCTCCAACAAAAAAGCGCAAATACTCGGATAGCTCATCCAACGCAGATGACATAACATCCGTGGGGGAGATGGAGACACCGCAGAAGAAATATGAATTTCTATATCAGTACTTTATGCAGCATGAAACGAACTCTGAGCTGAAACAGCAGTTCCTGATGCAGCACCAGCAGCACCAACAACAGCAGCAGCAGGGAAATGAAACGGATTTTGAATTGGAGTTTTTAACTAATTTCTATCAACAGAGCGAGCTAAAAAAAGTCAGCAACTATGACTTTTTGTTACAATATTATCGCAAATGTGAAGCAATATCCTTGAACACGAAGCCGCCTCAGCAGACTTTCAGCTCCAGCAAGAAGCCAACCATTGAGTTCCTTTTGCAATACTATCAGCTTAATGAGTCGAAAAAGTTTTTTCAGTTAGTTGCCTCGCCCCAAACGATGCCTGATGGGCAAGGGTACCAACCGTCGTCGCAGTTGCCGAACGCGACGGCGGATGAAACCATGAACGTTATCGGCGAACCGGAAGAGGGGCAGCAATTGCAGGAGCAATCACAGAATCATCAGGAACACCCTAACGTCGAGAGTAGACGACTTGGAAAAGAGCTGGCGCTGGCCGACGACAAGAAGGAACAGGAAAGGCTGAATAACAACAGCATTAATATCAACTCGAGCTCATCTGAATCAGCTCAGTTCCCCTCAGCTAGAGTTGAGGCATGCGAGACGCAATCAATTGAAATCAGAGACCATCAGCAGCCGGCAGCGACACCCACTTCAATGTCGATCACTGAGGATGAAAAATCTTTATTTGGCAGGTCACTACAAAAAAACGACAAAGAGAAGTCCCAGTTCTTTCAAAACCTTGAGGACTTTTTGGATGCCACCATGATTGAAAACAACTCACAGACTCTAACTTTTAACGATGACGACACTGCTAGCCAGAAAGATGATGCTAAAATATCCTCAACGCTCAAGGTCCATGAAGTGGAAAATGTAACTTCGGTGTCTCCGGTCAATGCCCCATCGAAGCAGAACAAGCGTCTACGCACGACAATACTTCCAGAGCAATTAAACTTTTTGTACGAATGCTATCAATCCGAGTCGAATCCCAGTCGAAAAATGCTCGAGGAGATATCCAAGAAAGTAAACCTCAAGAAGCGTGTAGTACAGTGA
Protein Sequence: MCFICKLSFGNVKSFSLHANTEHRLNLEELEQQLLNREYSSAIIQRNMDEKPQISFLQPLDINATCAVEKLILAPDANCTPLASEPEPELDHHDHYEPDQDRSQDKGVAQAMEQDSEHDQVQDPDPDPDQDQDQESPPPSQQHLALAQSQSQALPLSQPQPHRSPNSNSGNLAISPSSSSVTSVGNASGAASSFTIGACSEHINGRPQGIDCARCEMLLNSARLNSGVQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAAAAAAAASGKLLLSSSSPQGSGAGQQTVLGSSGSASASTAIISNSVGGNAAMVATPTPGCTGVGGVASGSVKPKPSFRCDICSYETSVARNLRIHMTISATDQFSYSPKPMKHGHGMGMGLGLGLGLGMPQGIGHSNEASGESGSDSQPLAKPDMWPTALYSCLICDSFSTNNLDDLNQHLLVDRSRQSSSASADIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGGARNEYKLQYQPQLSANVVQLMCNCCDFHTNSIQKLSMHTQQMRHDTMRMIFQHLLYITQQSRMHKESSPCTASEDAQCPCPDEDQQSMAMATIEKVLICQLCSFAAKNLYEMVQHVKGIRHMQVEQFICLQRRSENQEMPGLSEVYKVTERIRGSEDIIFEAGFNMATTAPVGGSSELGFAAATAGSSGAAAAAADSNILSPKSTSSCSTSCGKSIGRIASPSMNDFSLSASNSIPTTVFKCNLCEYFVQSKKDMASHIETVHPGAEGDDFMSIPTNTAALQAFQTAVAAAAIAAVQQRCSAINMPREADTEMDPCIDIKRERLEEQDDPMTGIEERKPTANIDVDSPGATATATTTTESKTTATATTAATTTPGVQCPLCLENGFREKSLLETHLTSVHSVTKDGLARLLQLVDSKAWSDSPSPCPSVTATTRTASNCHSKPEDCATTTGSVSTEDCVSTVFPAAAATSSTASSAGMQGLSCQQCEASFKHEEQLLQHAQQTQHFPEQNGEYICLATSHISRPCFTSFSTLSAMISHFKDSHMSLVISERHVYKYRCKQCSLAFKTQEKLTTHMLYHTMRDATKCSLCQRNFRSTQALQRHMEQTHSNDGAGAGVAAGITSTNTNSPRPPTPTPSYGEMEKLSSGERDPSIASEAGPKSNNTSRRSLSPLRLELQYSKETAQLSPSPSPHTLDTNQTQQQQHHQHLATLTAALLKQQQQCHPDAGILSADPLSLSAADFSQQLQGLQNLQNLQHMQQQFSAVAASSGMPINPVDMLNLMQFHHLMSLNFMNLAPPLIFGANAASGSTGSTAAAQNNGMTSASLSAPASQAGEMQIGSGASNLTGESTNANNPTAQHSINSNSQMNNNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGSSLAVHCHNQQQLQQQQHAQSNSFETKSESGSSDVMSRPPTPNSVAASNLYGSMNDLLSHQLESMGSNMGPPKKLQIAGKTFDKGTATVSSSATACNQFESNSSSSSNSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNSLFENEETKKQNINYACKKCSLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQNLSSEDSNSSMDIHHAGICPPGPLGPQTVSAPVSIVTPSGHAGSQPFGASPSPQHIFSKSSSLTDFSPSTTPTPPQRERSNSLDQPQRTVSKFDCDKCELQFSHLELLREHQMMHLMNPAALLAAAGQHPNPEASYGPFGSILQSLQHAAAQQQQHQQPPTKKRKYSDSSSNADDITSVGEMETPQKKYEFLYQYFMQHETNSELKQQFLMQHQQHQQQQQQGNETDFELEFLTNFYQQSELKKVSNYDFLLQYYRKCEAISLNTKPPQQTFSSSKKPTIEFLLQYYQLNESKKFFQLVASPQTMPDGQGYQPSSQLPNATADETMNVIGEPEEGQQLQEQSQNHQEHPNVESRRLGKELALADDKKEQERLNNNSININSSSSESAQFPSARVEACETQSIEIRDHQQPAATPTSMSITEDEKSLFGRSLQKNDKEKSQFFQNLEDFLDATMIENNSQTLTFNDDDTASQKDDAKISSTLKVHEVENVTSVSPVNAPSKQNKRLRTTILPEQLNFLYECYQSESNPSRKMLEEISKKVNLKKRVVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00611213;
90% Identity: iTF_00611213;
80% Identity: iTF_00611213;