Dtrs014745.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tristis
Gene Symbol
-
Assembly
GCA_018150885.1
Location
JAECWT010000207.1:237178-240367[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.036 2.4 8.5 0.9 1 22 355 376 355 379 0.84
2 8 0.00072 0.048 13.9 0.6 1 23 753 776 753 776 0.96
3 8 5.4e-05 0.0036 17.4 1.3 2 23 808 829 808 829 0.97
4 8 1.2e-05 0.00083 19.4 2.2 1 23 835 857 835 857 0.97
5 8 3.4e-05 0.0023 18.0 0.9 1 23 863 885 863 885 0.98
6 8 0.00031 0.021 15.0 1.2 1 23 891 913 891 913 0.97
7 8 0.015 1 9.7 0.3 2 23 920 941 919 941 0.96
8 8 0.00041 0.027 14.7 2.2 1 23 947 971 947 971 0.93

Sequence Information

Coding Sequence
ATGCGTCAGAAATGCGGCACCGTTTACACCTGGAACTGTGCTGGCGAACTGTATGCCATCGAGTGCGCCCTCTGCGAGGAGCGGCCCCTTTGCACGCTAAATGAGTTCACCACGCATATGGTGGTCTGGCACTCCGACTGGGGGGCCGAGGCGGCAGGAGCTTCCACGGATGACGAGGCAAGTTCAACTGCACCTGGAGCCGCCGTAGATGAGCTGATGCAGGAGGTGCTGGCAGAGCAGCGTACCAGCGAAGCCGACAATGAGTTAAAGCAGCAGCTGGTCCAGCAGTTAAATGCCATGGATCAGCCAGTGGCAGAAACAGAGGCAGAGGCAGCAGCAGCAGAAGAACCGATCGTTGTCAGTGAGCAAATGAAGTTCGCCCTTGAGAATCCAGCGCCCGTGCCTGAGGGCCAGCGGCTGACCACTCAGCATGTCAACCAGCTTATCGAGCTGTACCGCGCGGAGCCACGTCTCTGGAACCAATCGCATGCGGAGTTCCACGATACGGACCTGTGTCGCAAGTCCTGGCGTCGTATAACGGACACCTGGAGCGTGCACTGCGGCCGCCGCTTCACTGTCACCGATGTGCGCATACGAGTATCCACCCTGTGCCAGCGCTTCATCAAACAGCGCGAGCGCCTCGAAGCTGACGGCGAGCTCGACGACGCTGTCAAGTTCGTCCACTACGACCAGCTGGGATTTCTCTGCAAGCAGCAGGCGCTGCTCAAGCGTCAGCAGCACTTCATTCGCGAGAACCGCAAGCTGATCGAGCTCTATGAGCATTACCCGATCTTTTGGCACAATGTCCACAAGCGGCTGCGCTGTGCGGACATCGTGAGGGGGCGCCATGAGGCACTCCGTGATCTTCAGCTGGCCCTGCGCCTTTCTGGTATTAATCTGTCCTCGCTGGTTATTAAGCGGCGGCTGCAGTCTCTGAGGAAACGATATCGCCTGGAGAAGATCCGCTATCTGCACTGCGTGGTGGAGGGCAAGCAAGCGGAGTTCGTCGCCGGCTTTGAGCACTACGAGGAGATGGAGTTCCTTCATATTCACATTGATCCATATGTGTGCGCTGTCTGCGGCAAGATCTTTGAGAATTTGGCGAGTCACCAGGCGCACGTGCAAAGCAACTGCCATGTCCAGACGGAAATGGATGTTGGCCCAGAGAAAGAGAAAGAAGCCGAAGAGGGGGAGGGGGTGGATGAGAAGGGGGAGCGGGCAGAACTACAGGATCTTCAGCACGTTGAGTACCCGCATCAGGTGGAACAGAACTTTCAGCAGGTGGAGAATCTCCCACCTGCAGCGGACCTTCACACGACGATAATCTTCCAGCAGCTTCCAGATACCCCACAAGTGCAGAATAATGAAGATCTCCAAAAGGTGGAAGATATCCCGCAAAGGATTAACCTTATGGGAGATCTCCGGGTGGTGGATGCGGATAATCGTACATCTGTCGTGGAGAGGACAGTAAGGTCTGCGCCTGACCGCGAGCGGGAAACCTCTCTATCCAGTCTGTCCGAGGCCGGCTCCGCCAACAATCTGGAAGCTTTGCCATCCGTGGTGCAATCCGAGTCGGAGCACAGGGAGGGCTCGCCCGTCCGCCTCAGCCGGCAACAGACAATAAAGCTGATCAAGCTGTACCGAGCAAACATGTGCCTGTGGGATCCCAACCACCTGGACTACCATACACGCAAGCAGCGCCGCCTGGCTTGGCAGAGAGTCACGGAAGAGTTAAACAGGAGCGAGGGCACAGACACGGGCCAGAGATACAGCTGGCAGATGCTACACCGAAAGATCACGGATTACACAAAGTATTACCGCCGGGAGCGACAAAGGGATCAGGAAAAGAAGCTCGGGGAGGAGACCACCAGATGGAGCTTCTACGAAGAATTCCGCTTCCTGGACGACGTGCTTCCCATCAGCTGTGTAGTACAGAAGACGCTTAACCAGCGGGACAGTACCCTCAAGATCATCGACGTATACCAAAGCTATGCCCAGCTCTGGTGCACCGACCACCCGGACTACACGAAGCGGCGGCAGCGCCAGCGCCAATTGGAGTCTCTCTGCACGCGCCTGCAGGAGGAGTGCAACCTGCAGATTACTGTGGAGCGACTCAAGGGCCGGCTTATCGATTTTCGGTGCCAGTATAGGCAGTGCAAGGAAGCGCGGATAGCGGCCCTCAAGAAGGCCGAACCCTGGACTCCGGAGTACGAGTACTACGAGCAACTCCGCTTCCTCGAGCTGCACGTGTCGCCCTTCGTTTGCCCCCGATGCACGGCAGCATTCAAGCGTCGAACAGACTTCTTGCAGCACGAGCGCAACGTTCACCTGGATCAGGAAAAGGCCCTGAACGGCGAATATGGATTCGTGAGGCGACGCAGATGTCGAACGGACAAAGACAGCCCCAATGACCTATCCAATGTCTGCCACATTTGCGGCCTAAAGTTTTCGCTACGCAACAGTCTACTGGCTCATCTGCGGCGGCATCTCGGCCAGCGCACTCACATCTGCTCGGAGTGTCCCAAGAAGTTCTTCAACTCGACGGCCCTGCGCGTTCACCAGCGCAGTCACAGCAAGGAGTTGCCTTATGTGTGCGAGCACTGCGCTCGGGGCTTCGTCAACGCCAGCAAGCTAAACCAGCACGTGAAGCGGCACCGCAACCAACGCGATTTCCCCTGCAACCGGTGCGACAAGGCGTTCTACACTGCCCACGAGCGCGACCGACATATTCGCGCCCACCTTAACATACGCGACAAGGTCTGCCCCCACTGTTCGCGGGCCTTTGTCGTGGGCAGCGCTTATTACTCCCACCTTAACCTCCACCGCAGCGAGAAGCGCTACTCCTGCGCCAACTGCGGTCGCCGCTTTGCGCAGTACGCTGGCCTGTACAAGCACCGCCGACGCTGTATTCACACTGATGTACAGGCCGAGGATTAA
Protein Sequence
MRQKCGTVYTWNCAGELYAIECALCEERPLCTLNEFTTHMVVWHSDWGAEAAGASTDDEASSTAPGAAVDELMQEVLAEQRTSEADNELKQQLVQQLNAMDQPVAETEAEAAAAEEPIVVSEQMKFALENPAPVPEGQRLTTQHVNQLIELYRAEPRLWNQSHAEFHDTDLCRKSWRRITDTWSVHCGRRFTVTDVRIRVSTLCQRFIKQRERLEADGELDDAVKFVHYDQLGFLCKQQALLKRQQHFIRENRKLIELYEHYPIFWHNVHKRLRCADIVRGRHEALRDLQLALRLSGINLSSLVIKRRLQSLRKRYRLEKIRYLHCVVEGKQAEFVAGFEHYEEMEFLHIHIDPYVCAVCGKIFENLASHQAHVQSNCHVQTEMDVGPEKEKEAEEGEGVDEKGERAELQDLQHVEYPHQVEQNFQQVENLPPAADLHTTIIFQQLPDTPQVQNNEDLQKVEDIPQRINLMGDLRVVDADNRTSVVERTVRSAPDRERETSLSSLSEAGSANNLEALPSVVQSESEHREGSPVRLSRQQTIKLIKLYRANMCLWDPNHLDYHTRKQRRLAWQRVTEELNRSEGTDTGQRYSWQMLHRKITDYTKYYRRERQRDQEKKLGEETTRWSFYEEFRFLDDVLPISCVVQKTLNQRDSTLKIIDVYQSYAQLWCTDHPDYTKRRQRQRQLESLCTRLQEECNLQITVERLKGRLIDFRCQYRQCKEARIAALKKAEPWTPEYEYYEQLRFLELHVSPFVCPRCTAAFKRRTDFLQHERNVHLDQEKALNGEYGFVRRRRCRTDKDSPNDLSNVCHICGLKFSLRNSLLAHLRRHLGQRTHICSECPKKFFNSTALRVHQRSHSKELPYVCEHCARGFVNASKLNQHVKRHRNQRDFPCNRCDKAFYTAHERDRHIRAHLNIRDKVCPHCSRAFVVGSAYYSHLNLHRSEKRYSCANCGRRFAQYAGLYKHRRRCIHTDVQAED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00471878;
90% Identity
iTF_00564175;
80% Identity
-