Basic Information

Insect: Drosophila tristis
Gene Symbol: -
Assembly: GCA_018150885.1
Location: JAECWT010000189.1:6016390-6018849[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.75 50 4.4 0.0 1 15 233 247 233 250 0.81

2 8 4.5e-05 0.003 17.7 1.9 1 23 420 442 420 442 0.97

3 8 0.00019 0.013 15.7 0.7 1 23 448 471 448 471 0.97

4 8 0.023 1.5 9.2 0.3 1 23 477 500 477 500 0.93

5 8 1e-05 0.00068 19.7 0.6 1 23 523 545 523 545 0.98

6 8 2.7e-06 0.00018 21.5 0.8 1 23 551 573 551 573 0.98

7 8 0.0041 0.27 11.5 0.5 2 23 579 600 578 600 0.96

8 8 5.2e-05 0.0035 17.5 1.8 1 23 606 630 606 630 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.75	50	4.4	0.0	1	15	233	247	233	250	0.81
2	8	4.5e-05	0.003	17.7	1.9	1	23	420	442	420	442	0.97
3	8	0.00019	0.013	15.7	0.7	1	23	448	471	448	471	0.97
4	8	0.023	1.5	9.2	0.3	1	23	477	500	477	500	0.93
5	8	1e-05	0.00068	19.7	0.6	1	23	523	545	523	545	0.98
6	8	2.7e-06	0.00018	21.5	0.8	1	23	551	573	551	573	0.98
7	8	0.0041	0.27	11.5	0.5	2	23	579	600	578	600	0.96
8	8	5.2e-05	0.0035	17.5	1.8	1	23	606	630	606	630	0.92

Sequence Information

Coding Sequence: ATGAGATGCGCAGTGCAAAATTGCAAGAATGCCAAAACGGCCTCTGATAAAAATCCACAACTATGTTTCTTCAAGTTTCCGAGGAACGCTGATTTGGCCAAACGTTGGCTCTCATTTTGCGGCAATAAAGACGCCCAGATTATGAAGAATGGCAGTGTTTGTATGAAACATTTCAAAGACGACGATATCGTGGGCGCTCTAAAGTTCGAATTGGGATTGGCTAAGAAGAGGACATTGCGGCCGGGCGCAGTGCCGTGCTTAAACCGGAAAAACGAAAGCAAGTCGGAAAAGGCACGCAAAGAGCGCAACCAAAAGCGAGAGAACCAGAAACTGGTGGCCGAGCTTCTGGCGGATGCCGAGGCAAAGGAAATGGCTCAGGATGATATTGAACCCACTCCTAGCTATGTACGATATAATACTGGAATTGCATCGGCCCCGACCTTCGTCACTCCGTCGCCGCCCACTGATGGAAATGTGTGCCTGCAGACCATGTTACATGAAGTGGACCAAGACCCCCTCACAGCTGATGAAAACCACGTGAGCCTGACGCAGTTTAATAAGTGTCGTACTTGCTTTCGGGACTTTGAGTTTGATTCGAATGCCGAAGATCCCTTCGACAATGCCAACAGCGTTTTGCTTTTTCGCATTGAAGTCATTTGCGGAGTGTGGCTCAGCAATATCGAAGGTGGACCACATTACATGTGTCCGGATTGTCAGTGGGCCCTGAACACTGCGATCGAATTCCGTGAGAAGGTCATAAGTACCGAGGTGATGCTAACACAGGGGATGCCCGTGTGTGATAAGCCAGTAATCGAAATGGAGTTGGTCGCAACAGAGACTGATCAAAAGTGGACACCAGAATTGGCATCCATTGATTTGGAAGACGACGACGACAACGAGGAAGATGTACAGCATGAAGAAATTTATGATGAATCATATAGCCCTATCCATAGCCCCAATAAGGTGGATCAAATCGAAATATTAGAGCCAAGTGAGGAAAATGTCGAAGCTGCCCCAGCAGATCCACTCAGCGTTGCACGTGGGGCCAAAATCCTTAAGGAACTGATAAGCGAATTCACATGTCAGGATAAACCCAAAACGGAACGGGTAAAGAAAGAAACAGAAGCCGAGAAACCAGACATGGAACAGGCTCAGCCAAGGAAACCAAAAATTCGGGCAAGACGCCAGGCGAACCCCAAATCTAAAACGGAGCGAAATCGTATACGCCGCGCTCAGCTCAGAGACAAGCCTCCCTCCCATGTATGTGATCAATGCGGGCAGATCTTCCGCATGGTACACAATTTGCAAATTCATATGCTCCGTCACACACGCACTAAGAACTTCCATTGTCCAGAATGCCCAATGACATTCTACGATGCCTACATGAGAAACATTCATATACGCGTTCGTCACAAGGGCGAGAATCCCTTCGCCTGCCGATATTGCCCCGAGAAATTTGCATATGCGGGGAAGCGTCAGAAGCACGAAGCCAAAGTACATTGGGCACCTCCTCGTCTAAAAGTGAAGCGTATCAATCCTGCACCAATGCCAAGAGCTCAGACGCGCTACTTTTGCAAACTTTGCGATAAGAACTATGTATCGAAGTACGCTTTGGCCTGGCACATTAAATCGCATGGAGATGCGAACGCTTTCAAGTGCAATCTCTGCGACAAGAGCTACTCCGAGCCAGCGAAGCTGAAGCGGCACGAATTAACCCACGGGGAGAGGCCACTGCAATGCGATGTCTGTTTGAAAGGATTTTTTCAGCGCACCAAGCTCAAGGACCATGAGCTCATACACACCGGAGAGCGTCCTTTTAGGTGTGAAATTTGCAACGTTAATTTCCGGTACAAAACTAATTTAAAAACGCATGCAAACACAAAAATGCACCAGGAGAATCTACTGAAGACGGGGAAGAATGAACATATTGATAGTGACTAG
Protein Sequence: MRCAVQNCKNAKTASDKNPQLCFFKFPRNADLAKRWLSFCGNKDAQIMKNGSVCMKHFKDDDIVGALKFELGLAKKRTLRPGAVPCLNRKNESKSEKARKERNQKRENQKLVAELLADAEAKEMAQDDIEPTPSYVRYNTGIASAPTFVTPSPPTDGNVCLQTMLHEVDQDPLTADENHVSLTQFNKCRTCFRDFEFDSNAEDPFDNANSVLLFRIEVICGVWLSNIEGGPHYMCPDCQWALNTAIEFREKVISTEVMLTQGMPVCDKPVIEMELVATETDQKWTPELASIDLEDDDDNEEDVQHEEIYDESYSPIHSPNKVDQIEILEPSEENVEAAPADPLSVARGAKILKELISEFTCQDKPKTERVKKETEAEKPDMEQAQPRKPKIRARRQANPKSKTERNRIRRAQLRDKPPSHVCDQCGQIFRMVHNLQIHMLRHTRTKNFHCPECPMTFYDAYMRNIHIRVRHKGENPFACRYCPEKFAYAGKRQKHEAKVHWAPPRLKVKRINPAPMPRAQTRYFCKLCDKNYVSKYALAWHIKSHGDANAFKCNLCDKSYSEPAKLKRHELTHGERPLQCDVCLKGFFQRTKLKDHELIHTGERPFRCEICNVNFRYKTNLKTHANTKMHQENLLKTGKNEHIDSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487326;
90% Identity: iTF_00474531;
80% Identity: iTF_00611381;