Basic Information

Insect: Drosophila tristis
Gene Symbol: ham
Assembly: GCA_018150885.1
Location: JAECWT010000003.1:1400207-1441586[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.2 79 3.8 0.0 2 12 435 445 434 447 0.87

2 9 0.00075 0.05 13.8 0.3 1 23 497 520 497 520 0.93

3 9 1.8e-07 1.2e-05 25.3 1.7 1 23 526 549 526 549 0.96

4 9 1.1e-06 7.4e-05 22.8 1.6 1 23 555 577 555 577 0.97

5 9 8.5e-05 0.0057 16.8 3.8 1 23 583 605 583 605 0.97

6 9 0.0021 0.14 12.4 1.7 2 21 613 632 612 633 0.94

7 9 6.6e-09 4.4e-07 29.8 1.3 1 23 1079 1101 1079 1101 0.99

8 9 5.3e-07 3.5e-05 23.8 0.9 1 23 1107 1130 1107 1130 0.97

9 9 3.2e-05 0.0022 18.1 3.4 1 23 1136 1158 1136 1158 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.2	79	3.8	0.0	2	12	435	445	434	447	0.87
2	9	0.00075	0.05	13.8	0.3	1	23	497	520	497	520	0.93
3	9	1.8e-07	1.2e-05	25.3	1.7	1	23	526	549	526	549	0.96
4	9	1.1e-06	7.4e-05	22.8	1.6	1	23	555	577	555	577	0.97
5	9	8.5e-05	0.0057	16.8	3.8	1	23	583	605	583	605	0.97
6	9	0.0021	0.14	12.4	1.7	2	21	613	632	612	633	0.94
7	9	6.6e-09	4.4e-07	29.8	1.3	1	23	1079	1101	1079	1101	0.99
8	9	5.3e-07	3.5e-05	23.8	0.9	1	23	1107	1130	1107	1130	0.97
9	9	3.2e-05	0.0022	18.1	3.4	1	23	1136	1158	1136	1158	0.98

Sequence Information

Coding Sequence: ATGGCAAGGACCCCGACCGGCGAACGGACTGACGCGCCCTCGACGGCTCGCACGGGACCGGTGCAACGCCAGGAGCAGGAGAGCAGCACAGCACTACGTGATCTCGGAAGAGAAATCACGCAGCTTGTGGAGATGCTCGAGGATGGGAAGAGGCGCTCTATACACCAGCCTATGCGGGACTCGATCGAGAGCATACGGGTGCTGTATGAGCTGGTAGCCATCCAGCTACATGACGAAGGAGCCAAGGCGGTGATCAGGACTCACCAGTCCTCTCAGACCTCCCCGTTCTTTAGAACGGCTCCGGAGCCAAAGAGGAAGCAGGCTGCAGGTGCGCCAACACCAAGGACAAAGAGAAGCAAGGCATCAGTCGAGGCACAGACCACGCCAGGCGTAGCATCTGGAAACGACGCCCCCATCGAAATGGAGAACGAAGCGCCCGCGGAGACTCCTTTCCGGACCGTGGCCAACCGACGCGGAAGGAAGAAGAGGGAAAAGCCGCCCGGAGCTCTCGTGGAGAAGATGCGGCCGGACGCCATAATAATCTCCACGAAAGGCGAATCCAGCTACGCGGAAATACTGCGAAAAGTGAAGACGGATGAAACCCTTCACGGACTCGGAGACGCGGTCGCCAGGATCAGGAGGACGCAAAAAGGAGAGCTCTTGCTGCAGCTCAACAAGTCGGGACAGGAGACCGAGACTTTCAAGAGTCTAGTAGTTGGGACGCTGGGTGAGCAGGCGGAAGTCCGTACCCTGACGCATCGGGTGAGTCTCGAATGCAGGGACCTCGACGAGATCACCACTAGGGATGATATAGTGGACGCAATGAGAAGCCAGGCCCATGCTGGACCCAACTTTAATGGCTGGCTCGAGCCCACATCGGACGTGTCGACGTGGCTGAAGAAAATCCGCTCCGTGAAGGACATCGAGTGCATCGAAGAGGCTAATTTACACAATTACATAATGGGCGGCTGTTTGTGGTACGAAACGAATCGGTATATCAATGCAGGCAGTGAAATGGTAGTGGATGGCCGTCCCAAGACACCGTACCAGATCAATGACAACTTTATGGCCGGCGGCGGTGTCCTGGCGGCAGCAGCGGCCGCCGCAGCAGCCGCAGCAGCGGCAGCAGTCGCCTCGGGTGCCACCAGTGGTGGGGGCAGTTCATTACCCAGCGATGATCGGAGCGATCGAGATAATGGTTCCCTGTACAGCGGTGACGAATTCTCCAAAGATAAGAAAAACTCATCGCTGATCAGTCAAGGCGATATTGACTTCACAGACGACGAGAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAGGTCTATCCGGATTTAGAACGTGCGGCCAATAAAAGTGCCATTAAAGCGCGACTCGAATCTGGCCTGGACCTGGACCTGCAACTGGAACTGGAACTGGGACTGGACACTCTGCACCGAAACCTGGACGATCACCTGGTGGGCGCCCATCACTTCAAGCAGGACGAGTTCCCATGCAAACTCTGCTCGCAGCGCTTCAGCAATCGTCCCTTGCTGATCAAGCACGAGGCAATATCCCACAATAATATACGGAAATATTCCTGCGAGAACTGTAGCAAGGTATTTTGTGACCCATCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCATCCGTGTCCGGAGTGCGGCAAGACATTTGGCACCTCGTCGGGGCTGAAGCAGCACCAGCACATCCACTCCTCGGTGAAGCCCTTCGCCTGCGAGGTGTGCTTCAAGGCGTACACGCAGTTCTCCAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGTCGCATGCAGATCAAGTGCTCCAAGTGCAACCAGAGCTTCAGCACCGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACTCCACGGGCTCGTACCGCAACCAGCCGTTGGGCCGCCACCAGCATCCGCTAAACGCCACCTCCACCTCCGGCCAGTCCCAGGGGCCAGCGGGCGACTCCCAGGGCGAATCGGCATCGTCTGCTGCTGCTGCTGCGGCCGCCGCTGCCGCTGCCATGACGACGCCACCAAATCCCTTCCTCATGTTCCGCCCAGGACCTCCGTTCTTCCCAGGCTTCCCGCCGTACGGTCTGCCTGGCATCTTCCCCTCGAGTCCCCTGCGGGCCACCAACTTCCCGCTCTTCTTTCCGAAGCCGCCGATGGACATGGGCTGCGGCATGCCGCCCATGAGCTCGCCCAATGCCGCCTTCCGCCACCATCCCTTCGCCCTGGACCTGGAGAGACAGCAGGGCGGCGAGTCGCCCCCCCAGGAGCACCATCAGGCGAAGGCGGAGCGCGGCTCCACGCCCGACGAGAAGCAGCTCAAGGCGGAGCCTCTGCTGCAGGTGTCCGAAGAGGACGAGGAGGAGGAGGAGCCCGTCCAGTCCAGGGATATGAAAGTGGAGCCAGCAGATCCGCAGAAGGACCTCCGGGCTGAGCAGCGCATGGAGCTCAAGCGGGAGAGCTCGCCCGATGAGCAGCAAATCGAAGACGACAGGAAATCCATCGACATCGTTAGCACGCCGCCGCCCACGGACTCGACGACGGAGAAGCCCACCACCGCGGAACTGCCACTCGATCTGTCCATTTGCCGCAAGCGCTTCTCCGCCTTCCGCGCCCTGCAGCCGCCAGCGTCGCCGGCATCGCCCGCGTGGCCGCTGATGCTGCTGCCCGACGAGGATGCCGAGCCGCCGACGAAGCAGAGCCGCAAGAGCCACAGCTCGGGCGAGTCCTCCACCTCGCGGCAGTCCTACAAGGGCAGCAGTCCCACGCCCAGTGCCTCGCCCGGACCCACCCCATCGCCGTCGCCGCCCACGAGTGCGGGCGGGGAGATGAGCAGCATGTCGGAGGGTGCTGTGGCAGCGGCGCAAGCGTCGGCTGTGGCCGCCGGAGCGGCTGAGGCTGCCACGGCGGCGGCCATGGCCTGTCCGCGGCCACTGCACCCGCTGCTGCTGGAGGAGATCTACCGATCGCGGGCCCTGGCCGGACTCTCACAGCGCACGTTTCCTTTTTTATGCCCAACGGGCGGACGGCCAAATATTGAGGCGATGCTGACAGCAGGAGCAGCCAATGGCAAGGGCTGCTCGACACCCTCGACCAGGCCGCTTCCGCCCGTGAACTTCCGCGAGGCTTTGCGCTACGCCACCAGTGCCAGTGGCCGCTCTCCGAGCGCCCTCAAGACCAAGGACCGCTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGCTCCGCGAACCTCACGCGCCACCTGCGCACCCACACGGGCGAGCAGCCGTACTCCTGCAAGTACTGCGACCGCGCCTTCAGCATCTCCTCGAACCTGCAGCGCCACGTGCGCAACATCCACAACAAGGAGCGGCCCTTCCGCTGCGACCTGTGCGATCGGTGCTTTGGCCAGCAAACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGACGCCAATGGCACCGGCGAGGGCTGTGGCGACTTCAGGGACTCGCCCAGCTCCGCGGAGGCCGAGCGGGACGAGTACTTCGAGGAGATCCGCACGTTCATGAACCGCATGTACACGCCCAACAGCTTGGGCGGCGCCGATGGCGACACGGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTGTCCACCCGCCATTGCGATCTCGAGGAGATTGTGGAGCCCCGGATCGCGGGCCCGGGCTGCAGACAACCAACCAACCAACCGACAGACAACGATGACGATGAGCCCAGGCTGCAGCGGCAGCAGCAGCAGGAGGAGCCGGGCCGATTGCAGCCGCCTGGGCGGGTGCCCACACCGCACGTAGCAGCAGACCACACCACCATCACCACCACCATCACCACCACCAGCATCAGCCCCACCACCATAAACGAGCTTTTGCGCTCGGTAATACGAGCCGAGATGGCTGTCGTGTGGCATGCGAGGCGTATGCGCAACGAATCCACTCGGACAGCGCTCATACGCACAGTGGTAGCGCTGCAGCAGATTATGATGCACAGCGATGTGGAGAGCTCAGAAATGGAAATGGGCAACAACTGA
Protein Sequence: MARTPTGERTDAPSTARTGPVQRQEQESSTALRDLGREITQLVEMLEDGKRRSIHQPMRDSIESIRVLYELVAIQLHDEGAKAVIRTHQSSQTSPFFRTAPEPKRKQAAGAPTPRTKRSKASVEAQTTPGVASGNDAPIEMENEAPAETPFRTVANRRGRKKREKPPGALVEKMRPDAIIISTKGESSYAEILRKVKTDETLHGLGDAVARIRRTQKGELLLQLNKSGQETETFKSLVVGTLGEQAEVRTLTHRVSLECRDLDEITTRDDIVDAMRSQAHAGPNFNGWLEPTSDVSTWLKKIRSVKDIECIEEANLHNYIMGGCLWYETNRYINAGSEMVVDGRPKTPYQINDNFMAGGGVLAAAAAAAAAAAAAAVASGATSGGGSSLPSDDRSDRDNGSLYSGDEFSKDKKNSSLISQGDIDFTDDENGFDIRCEVCDKVYPDLERAANKSAIKARLESGLDLDLQLELELGLDTLHRNLDDHLVGAHHFKQDEFPCKLCSQRFSNRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHATCRMQIKCSKCNQSFSTVTSLSKHKKFCDSTGSYRNQPLGRHQHPLNATSTSGQSQGPAGDSQGESASSAAAAAAAAAAAMTTPPNPFLMFRPGPPFFPGFPPYGLPGIFPSSPLRATNFPLFFPKPPMDMGCGMPPMSSPNAAFRHHPFALDLERQQGGESPPQEHHQAKAERGSTPDEKQLKAEPLLQVSEEDEEEEEPVQSRDMKVEPADPQKDLRAEQRMELKRESSPDEQQIEDDRKSIDIVSTPPPTDSTTEKPTTAELPLDLSICRKRFSAFRALQPPASPASPAWPLMLLPDEDAEPPTKQSRKSHSSGESSTSRQSYKGSSPTPSASPGPTPSPSPPTSAGGEMSSMSEGAVAAAQASAVAAGAAEAATAAAMACPRPLHPLLLEEIYRSRALAGLSQRTFPFLCPTGGRPNIEAMLTAGAANGKGCSTPSTRPLPPVNFREALRYATSASGRSPSALKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYSCKYCDRAFSISSNLQRHVRNIHNKERPFRCDLCDRCFGQQTNLDRHVKKHEADANGTGEGCGDFRDSPSSAEAERDEYFEEIRTFMNRMYTPNSLGGADGDTEEYAGSDDQLSVSTRHCDLEEIVEPRIAGPGCRQPTNQPTDNDDDEPRLQRQQQQEEPGRLQPPGRVPTPHVAADHTTITTTITTTSISPTTINELLRSVIRAEMAVVWHARRMRNESTRTALIRTVVALQQIMMHSDVESSEMEMGNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -