Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: BCL11A
Assembly: GCA_035043205.1
Location: JAWNNE010000290.1:214708-232579[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.027 1.8 9.2 2.4 1 23 305 328 305 328 0.95

2 6 7.5e-07 5e-05 23.5 1.5 1 23 769 791 769 791 0.99

3 6 0.012 0.82 10.2 4.7 1 23 797 819 797 819 0.99

4 6 1.2e-06 7.7e-05 22.9 3.2 2 23 1096 1117 1095 1117 0.97

5 6 1.5e-05 0.001 19.4 3.3 1 23 1123 1145 1123 1145 0.99

6 6 2.8e-05 0.0018 18.6 0.4 1 22 1153 1174 1153 1174 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.027	1.8	9.2	2.4	1	23	305	328	305	328	0.95
2	6	7.5e-07	5e-05	23.5	1.5	1	23	769	791	769	791	0.99
3	6	0.012	0.82	10.2	4.7	1	23	797	819	797	819	0.99
4	6	1.2e-06	7.7e-05	22.9	3.2	2	23	1096	1117	1095	1117	0.97
5	6	1.5e-05	0.001	19.4	3.3	1	23	1123	1145	1123	1145	0.99
6	6	2.8e-05	0.0018	18.6	0.4	1	22	1153	1174	1153	1174	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCGACAGAGAACGATGCGGTCGCAGCGCAGGACATTCTCACGTGTGGCGCCTGTCAGAAGACCTTCGCACTGTCGGACATTGTCCGCTTCATTCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGTCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGTCGACCACTCAGTCTGGTCAATCGCCGTCCATCAATTTCGGCGCCAATCACAGGCCGCAAATCGGCGCCAGTTGCTGGCAGTGGTGCCACAGTTGCTGCCAATGCTATTGCCAGTgcggctgctgccactgctgccgctgcagcggcggcaacagcagcggctgccGCAGCCGCAGTTGCAAGCAGCGCTGCAAGCGGCTCACGAATACACACACCGCCGCCGAGTCCAGCGGATCTGCTCGCCGATGGCGCCAGCAGCACTCCCAAGCGCCTCGTCGATGAGAATGACAATACGACGCCCAAGGCGGACAGCGATGCGCTGACCACCGCCACAGGCGCAGCGGGATTGGAGTCGAGCATCGCTCACAGTCCACGCACACAGTTGGCGCAGGGGCAGCTGATTGGTCGCGAGGAGTGCGCTCTGCACGATGACAAGCCAAAGGTCAAGCAGGAGCCCTATGCCGACGATGAGCAGCTCGATGAGGAACTGCAGCTGGATCAGGCTCccgagcaggagcaggagcaggagcgaGAGCAGGAGCGGGAACTGAATGCGCAACTGCTGACACAGGCGACCGACAGAGACGAGTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCGAACACAGTGCACACAGAACCCAGCAATTACACATGTTCGACGTGCAAGACCCGTTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGACGGGCGGCTGTGGCGCCACCTTGACTGTGGCCACACCCGCCGCTCTTAATgctgcggcaacagcagcagcagcacaagccaCCGGCATCAGCGTCAGTCCAAATCGTTGTCCCAGTcccgcagcagcaactgttggtAGCGTCTccctgccactgccgctgcacGCGCTAATGGCGCAGTCGCCGGCGCCTaagcggagcagcagcaacagcagcgccgccgccgcagcagcagcagcagccgcaattTCTGCAGGCTCGGCCAatacgagcagcagcagcagcaatgtcagcagcagtagcaacagcgcCAATTCACCCacacagcaactgttgcagcagcgtgtacatcaccaacagcaacaacagcagcagcaacaggaacaacaacagcagcagcagcagcaacagcagcagcaacagagtcTAGTGCTAGCAGCAGGCATGCGTCATCATGCGCTTCTGGCGCCACCAGATTCGCTGCACGCGAACCCCTTCCAGCTGCTGCGCATGCCACTGCCACCTGCGCTGTCGCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTGTTTGGCCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTTAGCGAGCAGTTCCGGCATCATGGCTTCAGTCtggccgccgctgctgccgccgcccaGGCGCAATTCAATGccaacacacagcaacaacagcaacagctgcaacctGCTCAGCCCATTGCTGTCAATGTTCCTAATCCCGTCGAGCAGCGACCGCCATCGAGCAATAGCAGTCAGCGTGGCTCAGTACCGCCCGCTGCACTGCCGCCTCCGTCGCTCAGctcacagcagcaacagcaacaacaacagcagcaacagcagcagcaacagcagcagcaacagcagcaacagcagcaacaacagcaacaacaacaacagcagcagcagcagcaacaagtggctgcagcggctgctgctgctgcagctgcactgaGTCCAGCTGCTAGTCTAAATTTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAACAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCTGCCGCGCTTTCGGTTGCCGCTGCAACAACGCCTCCAGAGAAAGGTATCGAGAATGGACAGGTTACATCGACGCCCCGTTCCGCCAGTACGCCCACACCCACCAAGCCAGATACGGAACGGGAATCCGAGCTGGAATCGAGCTGCTATTCGTGCGGCTACTGCGACAAGAAGTTCCGCTATGAGAACAACTTGATTATCCACCAGCGGACGCACACCGGCGAGAAGCCGTATAAGTGCACCGCCTGCGATTTTGAGTGCTCGCACATACAGAAGCTAATGAAGCATATGCGGGTGCATCGCAGTCCAGCCGATCAGGGACACGATGGTGGCGATAATCATGATGGTCATGATGGCGGCAGCAATGCCGATTCGCTGGAAACGAATGAGGCGGACAACGATGACGATCCCAATCCCGATGAGTCCGACGAAGAGCTAAACGACGAGGATGCCGACGCGGATGCCGATGGCgaggatgatgacgatgatgagctGGACGATTGCGATGATGTTGACTACGAGGCCGAAGATCTGAGCGTCAACAATCGCATCGACGGCAAAAGTCAAAGCCCCAAGACGACCAGCTCCGGTGCCACATCGCTGGTGGGTGAGCTGATGGACAAGTTCGGGCTCTCCAATATTGCCCAATATTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCCGGACGCAAGGAAGCAgccgctgtggcagctgccgctgctgcggccgCCGCTGTTGTCGATAACAACAATCGCGGCTCGGCGGCCGGTGTAGTCAATCCAGGCGCTGGCAGCGGCGTCGCCTCCACCCAGCCACTGGGTGACAAGCTTAACGGTTTGCCGGTGGCAGCGTTGCGACTACGCGATGAATTCGCCAAGAACTGTAATATGTTTCAGCCACAGCCGCAGGATGCGCCGTCGCAGGTGCCGCTCTTCAATCCGTTTCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAGATCGATGGCGGTGATTGGTGGGGCATGTCCGCCCTGCATCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCGCTGGGCTTGGGCGGTGCCAATTCGCTGTTGCAAGGACCGCTGCTCAAAAAGGAGAGCCGGCAGCGCAACGATACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGTTCCAATCTAACGGTGCATCGTCGCAGCCACACCGGCGAGAAGCCATACAAGTGTGAACTGTGCTCCTATGCCTGCGCCCAGAGCTCCAAGCTCACGCGCCACATGAAGACGCACGGCCGCACCGGTAAGGATGTGTATCGCTGTCGTTTCTGCGACATGCCCTTTAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTGAACCAGGGCAaggcggctgcagctgctgcaaatgcagctaatgcagttgccgctgcccaagccgccgctgccgcccaGCAACTGCAGGCCGCTGCAcaggcacagcaacaacagcagcagcagcagcagcaacaacagcagcaacagttgccatcGCAATCGCAACTATCGCCGCCTTGTGCAATGGGCGTGGCTGTCGGCTATCCGCCGCAATTCGGGCATAATCTGTCGCTGGCGGGCAGCGTGAGTGGCGACAATGATTCGAATGCATCCTCCAGCCTGCCAGCGCACTCCTCCATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVAGSGATVAANAIASAAAATAAAAAAATAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSDALTTATGAAGLESSIAHSPRTQLAQGQLIGREECALHDDKPKVKQEPYADDEQLDEELQLDQAPEQEQEQEREQERELNAQLLTQATDRDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVETGGCGATLTVATPAALNAAATAAAAQATGISVSPNRCPSPAAATVGSVSLPLPLHALMAQSPAPKRSSSNSSAAAAAAAAAAISAGSANTSSSSSNVSSSSNSANSPTQQLLQQRVHHQQQQQQQQQEQQQQQQQQQQQQQSLVLAAGMRHHALLAPPDSLHANPFQLLRMPLPPALSQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFSLAAAAAAAQAQFNANTQQQQQQLQPAQPIAVNVPNPVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAAAAAAALSPAASLNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAALSVAAATTPPEKGIENGQVTSTPRSASTPTPTKPDTERESELESSCYSCGYCDKKFRYENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADQGHDGGDNHDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDADADADGEDDDDDELDDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVVDNNNRGSAAGVVNPGAGSGVASTQPLGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPSQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQLPSQSQLSPPCAMGVAVGYPPQFGHNLSLAGSVSGDNDSNASSSLPAHSSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00616427;
90% Identity: iTF_00558986;
80% Identity: -