Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: Hivep2
Assembly: GCA_035043205.1
Location: JAWNNE010000078.1:135752-143976[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0016 0.1 13.1 0.4 2 23 266 287 266 287 0.98

2 8 0.00024 0.016 15.6 3.2 1 21 293 313 293 317 0.90

3 8 0.011 0.7 10.5 0.2 1 19 959 977 959 980 0.93

4 8 2.9e-06 0.0002 21.6 2.0 1 23 1737 1759 1737 1759 0.99

5 8 1.2e-05 0.00083 19.7 5.3 1 23 1765 1789 1765 1789 0.92

6 8 0.00056 0.037 14.5 3.5 2 23 2271 2292 2271 2292 0.97

7 8 0.00085 0.056 13.9 1.2 1 23 2298 2322 2298 2322 0.91

8 8 0.0027 0.18 12.3 2.7 1 23 2343 2367 2343 2367 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0016	0.1	13.1	0.4	2	23	266	287	266	287	0.98
2	8	0.00024	0.016	15.6	3.2	1	21	293	313	293	317	0.90
3	8	0.011	0.7	10.5	0.2	1	19	959	977	959	980	0.93
4	8	2.9e-06	0.0002	21.6	2.0	1	23	1737	1759	1737	1759	0.99
5	8	1.2e-05	0.00083	19.7	5.3	1	23	1765	1789	1765	1789	0.92
6	8	0.00056	0.037	14.5	3.5	2	23	2271	2292	2271	2292	0.97
7	8	0.00085	0.056	13.9	1.2	1	23	2298	2322	2298	2322	0.91
8	8	0.0027	0.18	12.3	2.7	1	23	2343	2367	2343	2367	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAACGAGCaaggtggcaacaacaacaacaataataccagccacagccaacaccacaagcaacaacaaccagaacaacaacaacaacaacaacagcaccagcaacaaccacaatgtgttggccaacaacaacaacagcagcagcgatgatccaacaacagcggcagcaataaATGTCGACGGCTGGACGAGCTCAACCACTTTGcgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAACCGGAGTCGGTCGTTACAATGGCGGCGGCGCGCACCACATCGCTGTCATCGAATAGCTCGTTGTCGCCACCGCTGCCAGTTGCGGCTGCTCCTCTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATTTAGAATTCAGTGCCAATTTCGTAAATgccaacgacaacatcaacaacaataacaacagtcaTGATGAGAGCAAGAATGGCaatgttggtgttgctggtgcGCCTCGAACACGCACGCCGCTCAGCAACAGtaattgcaacagcaatattAACTATGCCAGCAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagcagccgtcgTTGCAACAttagcagcaccaacaacaacaacaacaataacaacaacaacaatagcagcagcagcaacaacaacaaatatacaaacagcagcagcaacagttgcaggaTTAGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCGTCGGTGCTGGAGAAGCACATTCGTGCCCACACCAATGAGCGACCGTATCCGTGCAACAACTGCGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGCTCCCGTTCCCATTTGGCGCGCATGCGCGGCCTCGATGTACCAGCCAATGAGACGGACGGACTCTCCGACCAGGATGGCGATGGGGagctgagcaacagcagctccgAGCTGCTAAGCGTTGAAATTTTGAGTCGCACAGATTCGCCTTATGATGAGGCCATGGCCTCGCCCacgccatcgccatcgacGCTGTCGGCGGCAAAGAGTACGTATCTGCAACAGccgcaattgcaacagcatatgctgcaacagttgccgctgGGCTCGCCTGCCGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTGCACTCGGCAACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCATCCCTCTATGCGCCCGGCACGctcaaggagcagcagcagcagcaggtactgcaacagcagcagacgctgctgcaaccacaacagcagccacataaACTgtcagcgcagcagcagcagcaaccatcGTTGGCCCATCCAACGCTCTCGCCCAGCACCCAGTTGAAGCTTAACAATCACATAAACTCGCatcagttgcaattgcagcttcagcatcagcaccaacagcagcagcagcatctgcatgCCCAGCAATCCCTGCTgttggcagcggcagcaaccaATCCGGTTGCATTGTCAGCcttgccaccgccgccgccgggcGTTTATTATTTGGGACAGCCGCAGTATTATAAcccaactgcagctgcaatgcATCAGCATGCGCTGGCCATTCAgcagatgcagttgcagcagcactttcagctgcaacaacagcagcaacagcatcaccaacagcagcaacagcatcagcatcagcaacaccagcagcagcagcagcaacagcagcagcagcaacagcagcagcagcaacaacagcagcaacagcagcagcagcaacattcgCCGCTGCTGAAggcgccacagcagcaacagcagcagCTGTTGCGCTCCAATAGCCAACAACAGGCGGCAGTCATTGCAACGACAGCATCGCTGCCCGCACCTGCTACACCCAACCCGCCTACCAATCTGAGCAGCTTTGCCAGCTCAAGCGGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTGATCTCACAGAACGAGGCCATTGTCGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaacaatagcagcaatggcagcaacatcaacagcagcagtataCCAACAACAGCGCACGCCAACacccacagcagcaacaacaacagcaatcaacaGCTGGGCGAGACTAAAGTGAACCTGGCACAGGCCATAgtacaaaaacagcagcagcagcaacagcatatgcaacaacagctgcagcagcaacaataccaattatatgtgcagcagcagcaacagcaactggagcCGCCGGTTAATGGTCTTCtgaagcgcagcagcagcagctctgcGTGCAGTTCAGCCAGCAGCGGCTATGCCAGCCTTAAGGGCACAGCAACCCCAACACCCGCCGCACCCACGGCAAGTGTgaaacagttgcaacagttaCCGCCGCCGCCATCGCCGTTGCCATTGCAACAGTTACAGTACCGCCAGGATCCGTCAACGCCAGTGCCcaagctggagcagcagctgcagttgcagcaacccTTGGCACCCAATCATGCCCAGCCTTTGAATTTGTCTGCCAAGCCCAAGCCACTAGCAATGCCAtcaaaaccaacagcaacagcagccgcagcaacaactgttggcaagatggcaacagcagcgcaggCGGCTACACCGAATATATCCATTATCAAGAATCTGCTGTTGAATGCACGTGGCTTGGCAGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCCTGCCCCATTTGCGCCAACGAGTTTCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTACTGTCAGGATGCGAACAGCAGTGCTCCCATCAGTCCCGCCTCATCGCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTTAGCCTGCCGGAGCTGCAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTCGCCAAGCTTGCCAAGGTCGCCTGGTCGCAGCTAAAAACCAAGCCAAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCTCAATCTCCCGCACGCACCTCAACCGTCACAGCagccaccaacagcagcagcagcagcaacaacaacataaacagcaacaacagcaacatcatcaatcacaacagcagcagcaatcacataccaacagcagcggcagcaactgttgtCATCCCGCCCAGCATTGATGCTTCCAGCGTTGCTTTGCGTTTTGTGGATGCACCGCTGCCATCGCCGGGTCCACTGCTCGGCAAGACACCGCTGGTCGATTATGCGGCGCCGCGCAAGGCTCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCTTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAACTGAGCAGTGGCGAGACAGCGTTCACTCATTTTGCTGGCAATCCGGATTTGCAGTTCAGTGCCAAGGAGGAGCGTCTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCTGAGTGTCCCGAGCTGAACGAGAGTCCCAAAATGATACGCACTCCGCTTTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCACGTCTCAGCGACGTCAAGGAGCGCAAACTTCTcgctgcaaacaacaacaacaacaacaacaacaataataataataataatggtttTCTGCTCAGCGCCTCAAATGCGCCgcatcattttcaatttcccaTCAATTCGATAACGGCCTTCAATCCGCTCACGCTGCCACCcatgagcaacagcagcggcaccaccagcagcagcagcatcaacaccAGCAATCTTGTGGATAAGGCAATACCCTATGTGCCGGGCATACCCGGTCCGGGCAGTTTATCGTTGCTGCCACCgccactgcagctgcagcgtgGACGCAGTCCCAATCGCAAACAGCCCAGTCCCAATTCGAATCCCAATCTCAATCTTAATCTCAATCCGCTGCTGGCAGCCGAGGGCCCGCTCAAGGCACTCTCGCCCTTCGGTGGCGTTCAGAACTTGCCCAGCGAATTCAGTCGACAGCCACCAACGCCAGCGCAGCGCAATGCGCTCCAAtggaccaacaacaacaacagcagcagcagcaacagcagcaataagtTGCCAGTGATTGTGGCTGACAAGAAGCCACCATTCAATTTTCTACGCATGGCGGATAATGTGAAGAGCTCCACTgtgcaggagcaacagccCCCGTCTCAATCTCAATCCCAGGCAATGGGTATGCCAGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCACGTGGACACACCCGACGAGGCgactgcaacagcagtagctgcagcaggagcaatCAAAACATCAATAGCAGCAACTTCTAttctggcagcagcagcaacaaccacaacgagcAGTGCCAAGTCGAAGTTCTTGCGACCCACCAGTCTGCCTCTGAAGCCGGGCACCTTTACGCCGAAGCGACATCATGGCATCACACCGACTGCGAATACACTGCCCCTAATCTCACCGGAAACGCCAAGACCCTCCAAGTCGTGCGTGCAACTGTATCTGAATGGTCACGCGTACACCTATCTGGGGCTCAAGTCCAGCACAAAGATGTTTTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTCGCCGGCATGCACAAACTGTCGATGTACAGCGTGTGGCAGGTATGCGAGGAGAATCAGCCGCATCCGCTCGGCTTCAAGCCCAAACAGGTGATGGCTCTGTACGATTCCCGGCAGAAGATGCTCGGCACTGGCTGCACCACAGCGATGGCGGGTGCCGGCAAACTGCAGTACTCCGTCTTCTGTTCACAGGAAACGGTCAGCACGAGCTCCACAACGGCCAACGGGCAGAGCAAGTTCTACCAGCACCAGCTGAAGCAGCCGCCGGCAATTGGCGCGCTCAGCGAGGCGAATGTGGCCGCCAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAGTCGAGCCAACTATTGGTCGGCGGTTACGAGTCGCATGAGGATTACACGTATATTCGCGGACGAGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCCTCCATGCTCAAGAAGCACATACGCACCCACACAGATGTGCGGCCCTTCACCTGCAGTCACTGCAACTTCAGCTTCAAGACCAAGGGCAATCTTACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGTGGACTTTGATCAGCAATCCTCGACATCAGCAGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCGGCTCGTGgtctgctgtcgctgtcgatGACGCCGCCGATACCGCAGAGTGTTTCACCGTATCCGGCACTGGTGCATGACACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCGTCGGCGGGCAGCGCAGCTGGCGGCTCGCAGCCAAAGCGGCAGGTGTGCTCGTTTACGTCGCCCAAGCCGCCGTTTGACTaccagaagcaggagcagtaTTACTCTAATCCCGAGGAGTCTAAACCCAAGCGCGGTGTGCCCAACGACGAGAGCAGTGCACCCATGGATCTGACCAAGCCACGCCCAATGCCCAGCATTTCAGTTGCCGCCTCTTCGCCCGTGCCggagcagctgcagatgcAGACGCCCAAATCGCAGGCACAGCAGATGCGCGACGTCATTTTTGGTGCGGGCAACAACGAGTGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGATAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCGAAGCGCGAAAGCGAAGGCGAGGATGTCCTCCTGCAGACTTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGCCGCAGCTACCTGGTGACCTCCACcaccaattccaattccaactgCATCTCCGCAAGCTCCAGCTACACCTCCATCTCTACCACGAGCAGCATTAGCTGCATCAGTAGCAGCTGTGTTGTGGCCACGCCCCTTGTTAATAGCAAACCACAGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAGGACACCAGAGTCGCCAACGCCATCGCCGGCTCTTGGGCATGCTGCCATCAAATCCGCCGAGGAGAGTGAGGAAAGCGAGACGCAATCGGATCAGGAGAAGCCAACCATAAAGTCCATTCCTGTAACTGTAACAGTGTCTGCTTCAGTCACTGTGCCCGTTTCCAGCGCGGAGATTCAGCAGCCGCACAATGCCAATTTGCctgctgcagtgcagcagccCGATGCCACCGATTTTAGCGGCgtactcagcagcagcagcaacaaaaatagcagcagcagtggagcAACTGCACCCACACGTATTGTGGTCGCCGGAGAGGATGGCTTCAAGACAACTCCAACCAGTGCCAGCAACGAATTGCAGTCTGGAGGAGCACAAGCTGGAGCAACTTATACGAATCGTGTggtgccaccgccaccgccgccaatTGCAAGTGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGTTGTCGCTGCACATGAACATCCACTACATGGAACGGAAGTTCAAGTGCGAGCCGTGCAGCATATCGTTCCGCACACAGGGCCATCTGCAGAAGCACGAGCGGAGCGAGGCTCACAGGAACAAGGTGATGATGACGTCGACATTTGGTGTGCCCACCACTTCCAATCCGCGTCCGTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAAACGCATGTCCAGAAGCTGGAGTGCTTGCAGAAGCTGCCATTTGGCACCTATGCTGAGATCGAACGTGCTGGCATCAGTCTGACAGAGATCGACACCAGCGATTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCGCAAAAGCTGCTCGAGAAGGATCCCAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTGTCGGCAGATGCACCTGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCCAAGCGGGCCAGCTCCATGTCCGAGGATGACACGCTGACCAACGGACTCGGActcagtcacagtcacagccatGGCCACAGTCTGAAGCGGCGTCTGCAGCacagcagcttcagcagcaATGGCGATGAGAGCGACAACCCAACAGATGCCACGGCAGCGGGCACTGGCTCTGGCACTGGCAGTGGCACTGGCAGTGgcactggcagtggcagcagcgagAAGCGTGCGAGAAGCAACACAAATGAGATCACACTGCCGACCCCGGTGGCTGTGTCAACGGCAACAGCCAGCAACTGa
Protein Sequence: MTLQQVASSATSKVATTTTIIPATANTTSNNNQNNNNNNNSTSNNHNVLANNNNSSSDDPTTAAAINVDGWTSSTTLRYLHKKFKRLASTTEPESVVTMAAARTTSLSSNSSLSPPLPVAAAPLLNGHVTVKVAPLLPARNLEFSANFVNANDNINNNNNSHDESKNGNVGVAGAPRTRTPLSNSNCNSNINYASNATLSPATFAQHQQQTQPTPAATAAVVATLAAPTTTTTITTTTIAAAATTTNIQTAAATVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEILSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQHRQSLDYKPYKPKFHNASLYAPGTLKEQQQQQVLQQQQTLLQPQQQPHKLSAQQQQQPSLAHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQHHQQQQQHQHQQHQQQQQQQQQQQQQQQQQQQQQQQQQHSPLLKAPQQQQQQLLRSNSQQQAAVIATTASLPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSSNGSNINSSSIPTTAHANTHSSNNNSNQQLGETKVNLAQAIVQKQQQQQQHMQQQLQQQQYQLYVQQQQQQLEPPVNGLLKRSSSSSACSSASSGYASLKGTATPTPAAPTASVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQLQLQQPLAPNHAQPLNLSAKPKPLAMPSKPTATAAAATTVGKMATAAQAATPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSAPISPASSPSSKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAATNSSSSSNNNINSNNSNIINHNSSSNHIPTAAAATVVIPPSIDASSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSGETAFTHFAGNPDLQFSAKEERLRRFTSSGGTMIPISECPELNESPKMIRTPLLSGGSFQEMSPRLSDVKERKLLAANNNNNNNNNNNNNNGFLLSASNAPHHFQFPINSITAFNPLTLPPMSNSSGTTSSSSINTSNLVDKAIPYVPGIPGPGSLSLLPPPLQLQRGRSPNRKQPSPNSNPNLNLNLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNNNNSSSSNSSNKLPVIVADKKPPFNFLRMADNVKSSTVQEQQPPSQSQSQAMGMPEVRHFNFDNVNKSQEALAPLHVDTPDEATATAVAAAGAIKTSIAATSILAAAATTTTSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKSSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFCSQETVSTSSTTANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLESSQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVHDTPAASPANSIGSSAGSAAGGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVPEQLQMQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTTNSNSNCISASSSYTSISTTSSISCISSSCVVATPLVNSKPQLNIAELPSIEVHEVRTPESPTPSPALGHAAIKSAEESEESETQSDQEKPTIKSIPVTVTVSASVTVPVSSAEIQQPHNANLPAAVQQPDATDFSGVLSSSSNKNSSSSGATAPTRIVVAGEDGFKTTPTSASNELQSGGAQAGATYTNRVVPPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDDTLTNGLGLSHSHSHGHSLKRRLQHSSFSSNGDESDNPTDATAAGTGSGTGSGTGSGTGSGSSEKRARSNTNEITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00482470;
80% Identity: -