Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: Bcl11b
Assembly: GCA_035043205.1
Location: JAWNNE010000299.1:210427-211769[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0013 0.088 13.3 1.8 5 23 236 254 235 254 0.97

2 6 1.8e-06 0.00012 22.3 0.7 1 23 260 283 260 283 0.98

3 6 6.8e-06 0.00045 20.5 2.1 1 23 289 312 289 312 0.98

4 6 3.9e-05 0.0026 18.1 0.4 2 23 319 340 318 340 0.97

5 6 1.5e-05 0.001 19.4 0.8 1 23 346 368 346 368 0.97

6 6 3.9e-05 0.0026 18.1 0.2 1 23 374 398 374 398 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0013	0.088	13.3	1.8	5	23	236	254	235	254	0.97
2	6	1.8e-06	0.00012	22.3	0.7	1	23	260	283	260	283	0.98
3	6	6.8e-06	0.00045	20.5	2.1	1	23	289	312	289	312	0.98
4	6	3.9e-05	0.0026	18.1	0.4	2	23	319	340	318	340	0.97
5	6	1.5e-05	0.001	19.4	0.8	1	23	346	368	346	368	0.97
6	6	3.9e-05	0.0026	18.1	0.2	1	23	374	398	374	398	0.91

Sequence Information

Coding Sequence: ATGAGCGGAGGGAAAGGCAAGGCAAATACCAAAGAGCATTGCTACGTATGCGACAGCAGCATCGAGGAGAATTATCTCGAAAATATGTTTGAGAAGCGATTTACGCCCAATGGCAATGAAGTCAATTGCATGGGCTCCATTTTAAGCCAGATTTTGGGTCACGAACTGAATATGGAGCAATTGCATTCCACGCAtttgtgccgctgctgcaagACAGATTTGCTTAAAATTGAAACACTTTACGATGAGCTCGTTGCGACATGCTCGATTGTAAGAAAACGGCACACAGAAACCCTGAAATTGTATGAACCTAAAGAGGGAATAGAAGATACCCCCAGTGAAATGGCCACAACGGATGTCAATTTGATTGAGGAGTGCGATGTGGACGTAGACGACCTGATCGAAGAGTGTTCCGAAAACTCCTACAATATAAATCATCCGGCCGAGGAATACTCTAATTATGTTGATGATTTGATTGTGGAGTGCGATGAGGACGTAGACGACCTGATCGAAGAGTGTTCCGAAAGCATCGATTATGTTGATGATTTCATTGAGAAGTGCTCCTATGGCGGCGGCTACGATAATAATAGTACGGTGGAGCAGCCGTTAAAGACGAGCCCACGTGCCAGCCGCAATCATCCTCTCATAGAGATTCCAATTCACACTGTAGAtgccaagcaaaacaaaagcaaaagttccATCTGCCACTGTGGGCAGAAGTTTGAAAGGCGTCAGTGGCTGGAGGATCACCAGCGCATCCATACGGGCGAGCGGCCTTTCAAGTGTGAGCTGTGCGATGCCCGCTTTGCGCAACGTTCCAATTGGCGCACCCATATGCTGACCACGCACGAGAACAAGGCCAACTTTAAATGCGACCAATGCGACAGGCAGTACAAGCGTCGGCGTCTGCTCAACAATCACATCAAGTCTGTGCACACCAAGGTGCGGGATTTACGCTGCACCCAATGCGATGCCACGTTCGGGAACCCGACGTACTTAAGCCAACATATGCTGCGCCACACGGATGAGAAGCGATACAGCTGCCTGATCTGTGACAAGCGATTCACTCGCCCCGAGAATCGAAATGCCCATTATTTTGTGCATAGCATACGCAAACCGTATGCCTGTGCCGTCTGCAACAAGGAATTCATGCGGaaacagcagctccagcagcacATTGCGACCAGCGTGCATCACAATCCGAAAATTGTGCGCCGCGAGCCTATGTTTAGCGAGGCCAACAATAAGAAGATACAGATGATTACTCTCGCCGCAGCCAAAAAATCTTGA
Protein Sequence: MSGGKGKANTKEHCYVCDSSIEENYLENMFEKRFTPNGNEVNCMGSILSQILGHELNMEQLHSTHLCRCCKTDLLKIETLYDELVATCSIVRKRHTETLKLYEPKEGIEDTPSEMATTDVNLIEECDVDVDDLIEECSENSYNINHPAEEYSNYVDDLIVECDEDVDDLIEECSESIDYVDDFIEKCSYGGGYDNNSTVEQPLKTSPRASRNHPLIEIPIHTVDAKQNKSKSSICHCGQKFERRQWLEDHQRIHTGERPFKCELCDARFAQRSNWRTHMLTTHENKANFKCDQCDRQYKRRRLLNNHIKSVHTKVRDLRCTQCDATFGNPTYLSQHMLRHTDEKRYSCLICDKRFTRPENRNAHYFVHSIRKPYACAVCNKEFMRKQQLQQHIATSVHHNPKIVRREPMFSEANNKKIQMITLAAAKKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00521631;
90% Identity: iTF_00574267;
80% Identity: -