Basic Information

Insect: Drosophila triauraria
Gene Symbol: ush
Assembly: GCA_014170255.2
Location: CM024334.1:931086-935778[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.44 11.1 0.0 1 20 247 266 247 268 0.90

2 9 0.00028 0.022 15.2 0.7 1 23 324 346 324 346 0.98

3 9 0.096 7.4 7.2 2.4 2 21 388 407 388 408 0.92

4 9 0.043 3.3 8.3 2.9 2 21 783 802 782 803 0.93

5 9 0.008 0.61 10.6 0.0 3 21 825 843 823 844 0.91

6 9 0.0052 0.4 11.2 0.0 2 23 912 933 911 933 0.98

7 9 0.0024 0.18 12.3 1.2 1 23 939 961 939 961 0.99

8 9 0.00061 0.047 14.1 0.8 1 23 988 1011 988 1011 0.96

9 9 0.36 28 5.4 0.5 2 20 1135 1153 1134 1155 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.44	11.1	0.0	1	20	247	266	247	268	0.90
2	9	0.00028	0.022	15.2	0.7	1	23	324	346	324	346	0.98
3	9	0.096	7.4	7.2	2.4	2	21	388	407	388	408	0.92
4	9	0.043	3.3	8.3	2.9	2	21	783	802	782	803	0.93
5	9	0.008	0.61	10.6	0.0	3	21	825	843	823	844	0.91
6	9	0.0052	0.4	11.2	0.0	2	23	912	933	911	933	0.98
7	9	0.0024	0.18	12.3	1.2	1	23	939	961	939	961	0.99
8	9	0.00061	0.047	14.1	0.8	1	23	988	1011	988	1011	0.96
9	9	0.36	28	5.4	0.5	2	20	1135	1153	1134	1155	0.91

Sequence Information

Coding Sequence: ATGTGTTCGCTGCCACGCTGCCACGAGATGTCGAATTTCTGGCGAAGCCAGGAGATGCAAAGCTGCAAGCTGGGCCGCTGCTGCTGCTGCTTATCCGGCGACTCCATCTCCATTCCATGTGTGTGCCATGTCCACGTCCACTTGCGGTCCGCCATAATCTCGGCCAGCATCGCCGTTGATTCCAAAGATTTAACCGCTCAAGAGATGGGCAGCGAGGAGAAGCAGCAGCAGCAGCTGGAGGATCAGCTGGATGATGAGTCCAGCGACCACCAGGAGGCCACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTGTGTTCGAGCAGCCAGAAGAGACTAATACCGAGCCCGATCAGGATTTGGGCGAGACCGATCCGCGGCAGCAGGATGTTGAGGATGAGCTGCCGGTCAACAGTCCCAGCACTCCGCCCAGGAGCAGCCCCTCCTCGCCCCAACTGATACCCAAGCTAGAGCAGCCCTCCACGCCTCCATCAGAGGCGGAGCCGGAGCCATCGCCCTGTCCCTCGCCCTCGCCCTGTCCACCCACCACGCCCAAGCTGCCTAAGCTGCGTTGCAATGCGCTCCTGGCCTCCGATCCCGCTCTCAAGCCCGACGCCAAGGAGCTGAATCTGCTGGCACCTCCTCCCCTCTCCCTCTCCATTAAGCCGGAGGCGCCACCGCAGGCGGAGAGCCTCGGAGAGCCGCTGATGAAGCCGGCCAGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCCCCCTCGACGCTGGAGGCCCACCAGGCCTACTACTGCTCGCACCGGAACAAGGAGACGGACGAGGACCAGGCGGGCAGTGACAAGTCGGGAGCAGGGGGCGGAACAGGCTCTGCTGGGGCAGCAGGAGCGGGAGGAGCAGGCTCATCCGGAGGCTCGTCGGAACCCCCGGCCAAAATGGCCAGGACGGGCAAGCAGTACGCCTGCTCCCAGTGCTCGTACAGTGCGGACAAGAAGGTGTCCCTGAACCGGCACATGCGGATGCACCAGACCTCCCCGGCGGCGCCCACCCTGGTCAGCCTGCCCAGTCTCATCCAGAACGGAATCCCACCGCCGGGCGTCACGCCCAACTCGCTGGAGGAGGGCTCTAGTCAACAGCAGACGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAGCACTACTGCAGCTCCCGGCGACCCGACGGCCAGCTCACCCCCAAGCCGGACACCTCTCCTGGCGGCCCCGCTGGCGGCGGCGTCGGACAGGGGCCGGCATCCTCCTCCTCGGCCTCGGGCGGAGTCGGTGCTTCCTCGCTGTCAGCGGCTCCCGGCAAGCTGAGTCCGCAGCAGGCCAGGAACAACAAGACGCCAACGCCCGCCATGGTCGCCTTGGGGCATGCGGCAGCGGCAGCGGCGGCGGCAGCAGCAGCGGCCGCTTCTCTCCAGGCGCCGCCCCATCCTCTGCCGCCCTTCCTGGCCCTGCCCACGCACCCGATCATCATTGTGCCCTGCTCGCTGATACGGGCGGCCAGCATCATCCCAGGACCACTGCCCACTCCCAACTCGGGCATTGTGAATCCGGAGAACACCTGCTTCACCGTGGACAACGGAACGATCAAGCCGCTGGCCACTGCCCTGCTGGGCACTAGCCTGGAGCCAGAGCGACCCTCGGCGCCCTCGTCGGCAGCTGAGGTGCCGGAGCCGAAGAGCAGTCCTCCGGAACCCAAGCGCAAGGAGGCGGGCGGAAGTCGTGAGTCCGCGCCCTTGGATCTCTCGCTACGCCGATCGCCGATCTCTCTGAACTCGCTGAGCCTGCGGCAGCGACACCTGCGCACTGCTCTCCTGGACGTGGAGGAAGCGCTCCTCGGCTCTGTCGGCAAAGAGATCGTGGAAACCTCCTCCTCCGCCGGTGGCGGCGGTGGAAGTGTCACTCCCGAGCAGATCGTGTGTGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGCCGCACCATCAGTCCCAGGAGCTCGGGGGCCGGCAGCAATGCCTCCATGTCGCCACCCGGGCTGAGTGTGGTGCCCAGCCTGCTGGACATGCGCTCCATGCTGCCGGCGGACTTTGGCCTGCCCGAATCGCTGCTGGCCAAGACCAACCCGGAGTTGGCCCTCAAGCTGGCGGCGGCAGCAGCTGCAGCGGCTGCGGTGGCCGGAGGCGGACCTTCGCCGGCTCAGACTAGTGCCGGAAATCCAGGGGGAACAGCTGCTGCCGGACAGCAGCAGCCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAATATCGTGTTCTGCAAATACGAGAACTACCTGGCGCACAAGCAGCACTACTGCTCCGCCAGGAACCAGGAGGGAGCTGCCGACGGGGATGTCAAGTCCGCTCAACTCATCTGCGCCGCCTGCGGCATCAAGTACACCTCCCTGGACAACCTGCGAGCCCACCAGAACTACTACTGCCCCAAGGGAGGCGCCACACCAGCAGGGACGCCCACAGATCCGGGCCAGATGGCCCTGGTGGTGAAGGAGAAGTGTGGCAAGTGCAAGACCCTGCATGAACTGGGACTGCCTTGTCCGGCGCCGCTCTCAAGCGCCCTCGCCGCACCCACATCCAACGCCTCCAACTCCTCGCAGCCCGCCTCCAACAGCCTGAACAAGTGTCCCGTCTGCGGAGTGGTCAGTCCCACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCACGGGACGGTGAAGGCCTATCGCTGCAGCATCTGCCAGTACAAGGGCAACACCCTGCGAGGGATGCGCACCCACATCCGCACCCACTTCGACAAGAAGACGACCAGCGACGTGAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGAGGAGGGTCGACTGTTCAACTGCGATTACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCACGTGGCCATCATCAGCTCCCCCTCGATTTCGCCGGAGACCAGGGATCAGGATCAGGTGATCTCGAGCTCCACGGCCAGCAACCAGCACTCGAGCACTTCCGATGGCTCCAATGGCGAGGCAGCGAGCTTCCACATCAAGTCGGAGCCCATGGATCCACCCTCGGCGACGCTGAGCCTGGTGCAGGAGAACAACAACTCCTCGCCCCTACCCACCCTGACGCCACACATCAAGGCCGAGCCGATGGACATTGGCCTGGACAGCCTGACCCTGCCTCCGCCGACGGTGGCTTCGCCGCTGGGCAACAGCAGCTTGGCCGCCGCCGCTGCAGCCGCATCGGTGGCTGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGCCCGGAGGCCAGCGACAGTCCCAGTCCGAACCTGGGAATCGGGAGCATTGGGAGCATCGGTGTGGTGGGCGGCGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MCSLPRCHEMSNFWRSQEMQSCKLGRCCCCLSGDSISIPCVCHVHVHLRSAIISASIAVDSKDLTAQEMGSEEKQQQQLEDQLDDESSDHQEATXXXXXXXXXXXXXXXAVFEQPEETNTEPDQDLGETDPRQQDVEDELPVNSPSTPPRSSPSSPQLIPKLEQPSTPPSEAEPEPSPCPSPSPCPPTTPKLPKLRCNALLASDPALKPDAKELNLLAPPPLSLSIKPEAPPQAESLGEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKETDEDQAGSDKSGAGGGTGSAGAAGAGGAGSSGGSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPAAPTLVSLPSLIQNGIPPPGVTPNSLEEGSSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGPAGGGVGQGPASSSSASGGVGASSLSAAPGKLSPQQARNNKTPTPAMVALGHAAAAAAAAAAAAASLQAPPHPLPPFLALPTHPIIIVPCSLIRAASIIPGPLPTPNSGIVNPENTCFTVDNGTIKPLATALLGTSLEPERPSAPSSAAEVPEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQRHLRTALLDVEEALLGSVGKEIVETSSSAGGGGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLSVVPSLLDMRSMLPADFGLPESLLAKTNPELALKLAAAAAAAAAVAGGGPSPAQTSAGNPGGTAAAGQQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGAADGDVKSAQLICAACGIKYTSLDNLRAHQNYYCPKGGATPAGTPTDPGQMALVVKEKCGKCKTLHELGLPCPAPLSSALAAPTSNASNSSQPASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSDVNEEHYMTCIFEEEEGRLFNCDYCNYASTYKGNVLRHMKLLHPHVAIISSPSISPETRDQDQVISSSTASNQHSSTSDGSNGEAASFHIKSEPMDPPSATLSLVQENNNSSPLPTLTPHIKAEPMDIGLDSLTLPPPTVASPLGNSSLAAAAAAASVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEASDSPSPNLGIGSIGSIGVVGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00480437;
80% Identity: -