Dtri010631.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila triauraria
Gene Symbol
-
Assembly
GCA_014170255.2
Location
CM024336.1:6675570-6678134[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.3 1e+02 3.6 6.2 1 23 297 319 297 319 0.98
2 11 3.1e-06 0.00024 21.4 0.8 1 23 325 347 325 347 0.99
3 11 0.00025 0.019 15.4 3.3 1 23 353 376 353 376 0.97
4 11 0.33 25 5.5 3.8 1 20 382 401 382 404 0.95
5 11 0.012 0.89 10.1 1.8 1 23 410 432 410 432 0.97
6 11 3.7e-05 0.0029 18.0 1.2 1 23 438 460 438 460 0.98
7 11 0.00047 0.036 14.5 2.9 1 23 468 491 468 491 0.97
8 11 0.19 15 6.3 0.9 2 23 498 519 497 519 0.96
9 11 0.0012 0.096 13.2 1.3 1 23 525 547 525 547 0.98
10 11 3.6e-06 0.00028 21.2 1.5 1 23 553 576 553 576 0.96
11 11 5.8e-07 4.5e-05 23.6 2.5 1 23 590 612 590 612 0.97

Sequence Information

Coding Sequence
ATGCCGAGGAAAGCAAAAAAAAACCAGGATGGAGAGAACCTGAAGACGTTCTTCAATAATTTCCACAAGGAAATAGGTGAGGGCAGCGATGACAAGGTGGTGAACAGGATCATGAAGGCCATTGACGCAGAGGACGGCGACTTGGACTACGAAGATGACTCGGATCAGGAGGCAGAGCAGCCTTCGGCTGAAGGAGAAGGCGCAGATGAGGAGGATGAGGAGGAGTTTGATGAGGACAAGTACTTCATAGATGACGAGGGAAATTGTTACATCAAAACGACGCCCAAAAAGCGAAAGGAGTTGCAGAAGAAGCTGAAAGAGAAGACGGAAAAACCCGGAAAGAACACACGATCGGCGACCAGCAAGGCCACCAACAAAGCCATTAATCTGCGGCCTGCCAAGTCGCCACCAAAGGGCGCCGCTGCCAAGAGCACACCGGAACCGAAGCCCATCAGCGTCCGTCCGGCGCGAGCAGCGGCAGCAGCAGCTAAGCCAAAGCAAGTGGATATGCCCCCGCCTCCAGCACCTGTACCGGCGCCCTCACCCGCAGTCCCGCCCAAAAGGGGCAGACCCAGGAAAACGCCACATGTGCCGAAACCTGAACCCATAGACCTGGAGCGGGAGATTGAGGAGCTGGTGGATGACCCCGAAATCAGTGCAGCGGACTTGAGTGATCTCGCAGACTATACAGTGGACAGTGCTGCCGTTGAAGCAGACAACTCGGTGCTGAGACCCAACGAGGATGAGGTATACGAGTTCGAGGACAACGCCGCGGTGGAGTCGGCTGGGGAGGCAGACGACAAGCAGGACTTGGACTTTGTGCTGACCGGCAAGCAGTTGAAGCTTAAGTCGGATGCGACTCCCGCCAAGAAGGCGGGAGCTAAGCAGTACTCCTGCTCGCAGTGCTCGTACACGTCCAGCAAGAAGTTTCTCATCACCCGCCACTGCCGGACGCACGACGTGGAGCCGGCCTTCAAGTGCTCCATATGCGAGCGCTCGTTCCGGACGAACGTCGGTCTGGTCAACCACACAAACACTCATCTGGGCAAGAAGCCGCACAAGTGCAAGTTCTGCGAGAACGCCTTCACGACCAGCGGCGAACTGATCAGGCACACACGCTACAAGCACACCAAGGAGAAGCCACACAAGTGCACGGAGTGCAGCTACGCCAGCGTGGAGCTGACCAAGCTGCGTCGCCACATGACTTGTCACACGGGCGAGCGGCCGTTCCAATGCCCGCACTGCACGTACGCCTCCCAGGACATGTTCAAGCTGAAGCGTCACCTGGTGATCCACACGGGCGAGAAGAAGTACCAGTGCGACATATGCAAGTCGCGATTCACACAGTCCAACTCTCTGAAGGCCCACAAGCTCATCCACAGCGTCGTGGACAAGCCCGTCTTTCAGTGCACCCTCTGTCCCACAACCTGCGGACGCAAGGCGGACCTGCGCATCCACATCAAGCACATGCACACCTCGGAGAAGCCGCTGACGTGTCGCCGTTGTAGCCAGGAGCTGCCCGATCGTTACCAGTACAAGCTGCACGTCAAGTCGCACGAGGGCGAGAAGTGCTACCGCTGCAGCCTCTGCAGCTACGCCTCGGTGACCCAGCGTCACCTGGACTCGCACATGCTCATCCACCTCGACGAAAAGCCGTTCCAGTGCGAGCACTGCCCGATGGCCTTCCGCCAGCGACAGCTTCTGCGCCGCCACATTAATCTATTGCACGATGCTCAGTACCAGCCGCCGGAGCCACGCGCCAAGGTGCACCAATGTCCCAGCTGTCCGAGGAGCTTCACGCACAAGGGCAATCTTATACGACACATGGAGCTGCACGACGATTCGGTGAACATCCGCGAGAAGCAGCTGCGCCTGAAGATGGGCAGGAATCTGCGCATAAAGAAGGATGGAACTATCATCAAGCTGGTCAAGGAGACGGACTTTCAAAACAAGGAGGATAACGTTGAGGAAGACAACCCAGAGACCTATGACCTGGCCGAAATCTTAAACTCTGACGAGGAGGACGGCGACGTGGAGATCGTTCCCAGCAATGTCATCAAGCCTACGGCGGCCAAGCCAAAGCCCGTCATCATCAACAAGCAGGCCGGCAAGTCTGCCTCCGACAAACAGCCCGTGATCATCAACAAACGCCTTCGAACGCAAGGCGGCACTAAGACGTTCCACATCAAGGAAGAGCCGGACAACTCGGATTTCACCCTCGAACTGCAAGGCGACGATGGCCAGTTGATGGTCGTGGAGCTGGTTAACGGCGACGAGGATGTTGTGGTCAAGCGAGAGCCGAGTGCGACCAATAAGATAAGTGCCACCAACTGCTTTGGATTCGAGGAGGATGACGATTACGAAGACTATGATCCGGCGGATGAAGTGGACGACGCTTCGCAGGAGTTTCTGCAGCTGATGGATATGATTGAGCAGGATACTTAG
Protein Sequence
MPRKAKKNQDGENLKTFFNNFHKEIGEGSDDKVVNRIMKAIDAEDGDLDYEDDSDQEAEQPSAEGEGADEEDEEEFDEDKYFIDDEGNCYIKTTPKKRKELQKKLKEKTEKPGKNTRSATSKATNKAINLRPAKSPPKGAAAKSTPEPKPISVRPARAAAAAAKPKQVDMPPPPAPVPAPSPAVPPKRGRPRKTPHVPKPEPIDLEREIEELVDDPEISAADLSDLADYTVDSAAVEADNSVLRPNEDEVYEFEDNAAVESAGEADDKQDLDFVLTGKQLKLKSDATPAKKAGAKQYSCSQCSYTSSKKFLITRHCRTHDVEPAFKCSICERSFRTNVGLVNHTNTHLGKKPHKCKFCENAFTTSGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPFQCPHCTYASQDMFKLKRHLVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCTLCPTTCGRKADLRIHIKHMHTSEKPLTCRRCSQELPDRYQYKLHVKSHEGEKCYRCSLCSYASVTQRHLDSHMLIHLDEKPFQCEHCPMAFRQRQLLRRHINLLHDAQYQPPEPRAKVHQCPSCPRSFTHKGNLIRHMELHDDSVNIREKQLRLKMGRNLRIKKDGTIIKLVKETDFQNKEDNVEEDNPETYDLAEILNSDEEDGDVEIVPSNVIKPTAAKPKPVIINKQAGKSASDKQPVIINKRLRTQGGTKTFHIKEEPDNSDFTLELQGDDGQLMVVELVNGDEDVVVKREPSATNKISATNCFGFEEDDDYEDYDPADEVDDASQEFLQLMDMIEQDT