Dtri016416.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila triauraria
Gene Symbol
zfh1
Assembly
GCA_014170255.2
Location
CM024337.1:34467920-34472224[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.5e-05 0.0019 18.5 1.0 1 23 151 173 151 173 0.97
2 15 0.00077 0.059 13.8 1.2 3 23 181 201 179 201 0.94
3 15 0.00025 0.02 15.3 0.2 1 23 369 391 369 391 0.98
4 15 0.00013 0.0096 16.3 0.8 1 23 397 419 397 419 0.98
5 15 1.3e-05 0.001 19.4 2.3 1 23 451 473 451 473 0.97
6 15 0.00054 0.041 14.3 3.1 1 23 508 530 508 530 0.95
7 15 0.01 0.77 10.3 1.3 1 23 536 559 536 559 0.97
8 15 0.025 1.9 9.1 0.4 3 19 568 584 567 585 0.95
9 15 0.00015 0.011 16.1 5.6 1 23 594 616 594 616 0.97
10 15 0.043 3.3 8.3 0.4 2 23 622 643 621 643 0.96
11 15 8.5e-06 0.00066 20.0 1.0 1 23 652 674 652 674 0.98
12 15 0.00097 0.074 13.5 0.1 3 23 682 702 680 702 0.97
13 15 5.2e-05 0.004 17.5 0.5 1 23 708 730 708 731 0.95
14 15 0.034 2.6 8.6 0.3 1 23 741 763 741 763 0.97
15 15 0.0052 0.4 11.2 0.2 1 23 1311 1333 1311 1333 0.97

Sequence Information

Coding Sequence
ATGAACAACCAGGGCTATGGCGGCATCCAGTGGATACAGCACCACCCCGCCGCGGGCGACTCTTCCGAGACGGACATCCTGGAGCACGATGACGCCGACGGCGACGATATGGTGAGCGGAGCGGACGCTGACCCTGATGGCGATGGGGATGCTGACCTGGACCATATGGCCGCCGAGAACCTGATCTTTATGGCGCGCGACGGCCAGCTGGGAGAGATTATCGCCGCCAACGAAGGAACTGTCCTGGTGACCGCCGATGGCACTACGGTGGCCTATGCAGAGTCCTTTGACGACGACGCCCAGGTGGTCACCGAGGAGGTTATCACCGACGACTGGGTGCAGCACCAAGGAGCCGAGCGCGTGGAAATCGCCGCCGAGCAGATAGCTGGCATCAGCAGCTCTCAGGAACTACTGGACATGGAGCAGGATGAGTACACGGCCCTGCGACCCTATCCCTGCGACTTTTGCAGCCGACGCTTTCGGAAGAAGGCCAGCTTGAACAACCATATGCTGGCCCACCAGAACGACAGACCTCATCTCTGCAAGCTGTGCGGGGCGCGCTTCTCACGCCGGGCGGAGCTCATTAGCCACTTTAAGGCCCACGCCGAGGCCCAGGATGCTGCGGATGCCGAGGAAGCAGCTGCCGCCGCCGCTGTTTCGGCCTCTTCCTCCATTAAATTCGAGCACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCCTCCCCCTGCTCCATCGCGCGGGAGAATTAGCAGGCTGAAGCCCAAGGAGGAGAGCAGCCAGTTCATCGTGATTACCGATAAGCCGGGCTCCAACGAGCTGCAGGACTACATAAACAGCGAGCCGGCGGCTCAAACAGTGGTGCCAACATCGCAGCCAATGGCCATCGATCCTCCGCCTCCGCCGCAGCCAAACTTCCCGGTGCTGGACGACAGCAAGCCCTTTGTGTGTCAGCAGTGCGGACTGGCTTTTGCACGGGAAAAGGCTCTAGTCTCACACACTAAGAACCATCGCGTGGATTCCCCCTTCGAGTGCAACCAGTGTCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCACCAGTTTGAGGAGAGCAACTCGGAGTATGATCCCGCCTCCGGCGATGATAGCGCAAGCGAAACGACGGAGCCGGAGGAGCAGCTCTACGGGGAGTTCTACTGCAACGAGTGCGGCATTTCCTTCCATCGCCAGGATCTGCTACGTCGCCATGCCAAGCAGCATTTTAAGCAGCAGGATCATCAGACGGCGGCAGGAGATGGGAGCTGCTCGGATATCACTGCTAGCGGGGATCATGCGGCGCATGCCAAAGATGGCAACGGCGGCCACTGTTGTCATACGTGCGGTAAATCATTTCCCAGCGCTTCGGAGATGCTTTCCCATGCCGAAATCCATGCAAGGTTTCCCCCCTTCAAATGCGTCCTTTGCGGCATAAGTTTCTACGAGGAGCAGGCCATCAAGCGACACCTGCACACCCGCCATCCCAACGAACTGAAGGCCAACTCTTGCGTGCTCTGCGGCAAGGAGTGTCGCGACCGCAAGGCCCTGATCAAGCACGCCTGGGACCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCTCGTCTGAAGAGGCACATGGCCTCCCACCGGGACAAGTCGGTGGTGTGCGAGGTGTGCCAGGAGGAGTTCCCCGACGGACGGACCTTGTCCAACCACCGGCACTCGCACAGCACCACGTCGCCGGGCAAGCTCTTTCCCTGCCATGAGTGCGGCAAGACATTCGGATCGCGCAGCTCCCAGCAGATCCATGTGCGCATCCACACGGGCGAACGGCCCTACGGCTGTCGCTACTGCTGGAAGGCCTTCGCTGATGGCGGGACGTTGCGCAAGCACGAGCGGATCCATACGGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGCTCCCACCACTCGGGGCTGGATGCGGTGCGGAATACGTACCACTGCACGGTCTGCTCCGAGGATCTGGCCTCTTCCAACGACCTCATACAGCACCTCATCCAGCACAGTGACTCAAACACCGCCAAGCAGCGTCAACCGGTCACGGGACCGCGAAAGTACAAGCGTCGGCGCAAGCTGCAGCCTCACGAGATTGCGCACATGCGGGCGGAGCACAAGGATGCCAACGGCGACGAGGAGGAGGAGATCCTCGGCGGCGAAGGGGAAGGCGAGGGAGATGAGTACGCCAGCGATTTGGACATCTGCGACTTTGACGTAGAGAATGTGGACGACATTTTTGAAATGGCCGAGTCGTCGCCCAGAAAGGAGAAGCGCAAGCGAGCATCGGCGGCAACCACGAAGACAGAACCCAAACCTGTTGCCAACGGCGGCGGATCGGTGGTGAAGCCTGTCCAGGAACAGAAGATCAAAGCCAAGCTGCGCTATGACTCCACCAGCAGTCAGCAGTCGGATCGCATCTGGGAGGAGAAGTTCCTGCAGGACAGTCAGGCGGCGCTCTTCCAAATCGATTCGCTGGTGGTGGTCAACGATACCCATCTGCAGCCCGCGAGCTCAGCGGCCATGTCCAAGACGAGAGGTGGAGCCAAGCAGCAGCAGGGAAAAGCAGGGCAGGCCAAGCAGCCCGTTGAAAGAGCAGGAAACTCCAATCCCTCTGCTGCAACCTCGGTTACTACATCTTCAGCCTCCACCTCCGCCTACACTTCCACTTCCAGCAGTCGCAGCAGGAAGAAGACGGCCGCCAACAAAGCACCCCCTGCCAGCAGCAGCTCCTCGCGACCCCGGATGATTCACACGGAGAAGGCCAAGGTGCCGACCAGGGGAGTAGCTGGCGGAGAGTTGGCCAAGAAGACACGCTCCAAGACCTACATCACCCGCACGGAGACGACCAATCTCACCAGTCTGGACAAGTCGCGCAGCAGCAGAGCCTCCAACATCGTGGACGACTACGAAATCATTTCGCCAGCCACCCATCCACCGAACCAGATCAGCTCCAGTCCCCTGCACATCAAGCAGGAGCAGGAGCAGCAGCACCGTGTCCAGATGGTGTACGACGACAATCTCCTGATAGACGCTGCTCTGCTGCGGGAGAAGACATACGAGAAGTTCAACCCGAGCATTGTAAACGATCTGGAGGAGATCCTCCGCTCGCCGCTCAAGCACGAGCGAAATTCCCGCCTGCGATTCACCAGCGAATCCTCGAACACGCCACAGTTCCTGCCCGAGGAAGAACAGAATCTGATCAAGATCGAACCCACGTCTCCGGACTTGCGGGAGATGGTGGAGAGTCAAAGTCAAAGGGTCAGAGTGCCAAGTGGAAACACACCGTCGCCCTCTTCTTCCTCCGCCGCCAGAACTTCGCGTCATCGTCCGATCACTGCCAATGGACCAAGGGCAGGGAGCAAGAGGTCCGGCGGAGGCATAAGTGGCGGCGCTAGCAAGTCCTCACCTGCCTCCGGAGTGGCGGCCAAGAAAGTGAGCACTGCTGCCAGTAAGGTCAGCGGCAGCAGCTCGTCCTCGTACCTCAATTACGGGGTGGATGCCTACAATGTGAACGTACCTGCCAGCGCCAGCACTGCCGATGTGGGCAGCGGATTCTTCTCCATCTCAGAGGTCGTATCCGCCGCCGATGCCGCTGATGCGGCGGCAAAGGCGGCGGCGGCCGGGAAACCGGAGCGGAAAACGCGCAGTTTCGAGTGTGAAATGTGCTCGGCAATCTTTTATGACCGAGCCCAGCTACTGGACCATGTGCACATCCACATCTAG
Protein Sequence
MNNQGYGGIQWIQHHPAAGDSSETDILEHDDADGDDMVSGADADPDGDGDADLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEEAAAAAAVSASSSIKFEHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPPAPSRGRISRLKPKEESSQFIVITDKPGSNELQDYINSEPAAQTVVPTSQPMAIDPPPPPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETTEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDHQTAAGDGSCSDITASGDHAAHAKDGNGGHCCHTCGKSFPSASEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDANGDEEEEILGGEGEGEGDEYASDLDICDFDVENVDDIFEMAESSPRKEKRKRASAATTKTEPKPVANGGGSVVKPVQEQKIKAKLRYDSTSSQQSDRIWEEKFLQDSQAALFQIDSLVVVNDTHLQPASSAAMSKTRGGAKQQQGKAGQAKQPVERAGNSNPSAATSVTTSSASTSAYTSTSSSRSRKKTAANKAPPASSSSSRPRMIHTEKAKVPTRGVAGGELAKKTRSKTYITRTETTNLTSLDKSRSSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVQMVYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNSRLRFTSESSNTPQFLPEEEQNLIKIEPTSPDLREMVESQSQRVRVPSGNTPSPSSSSAARTSRHRPITANGPRAGSKRSGGGISGGASKSSPASGVAAKKVSTAASKVSGSSSSSYLNYGVDAYNVNVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00480304;
90% Identity
iTF_00483109;
80% Identity
-