Basic Information

Insect: Drosophila testacea
Gene Symbol: Znf574
Assembly: GCA_035043265.1
Location: JAWNND010000737.1:540718-542982[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.9 2.2e+02 2.8 2.6 2 23 335 357 334 357 0.94

2 10 0.063 4.8 8.1 0.1 6 23 367 384 367 384 0.98

3 10 0.0011 0.087 13.5 2.4 1 23 390 412 390 412 0.96

4 10 0.45 35 5.4 0.6 1 14 418 431 418 441 0.74

5 10 0.0001 0.0076 16.9 1.3 1 23 449 472 449 472 0.96

6 10 0.17 13 6.7 0.4 3 23 480 501 478 501 0.92

7 10 0.53 40 5.2 0.2 2 23 513 535 512 535 0.93

8 10 0.0085 0.65 10.8 4.1 1 23 542 565 542 565 0.93

9 10 5.6e-07 4.3e-05 23.9 1.4 1 23 571 593 571 593 0.98

10 10 0.043 3.3 8.6 3.3 1 23 599 622 599 622 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.9	2.2e+02	2.8	2.6	2	23	335	357	334	357	0.94
2	10	0.063	4.8	8.1	0.1	6	23	367	384	367	384	0.98
3	10	0.0011	0.087	13.5	2.4	1	23	390	412	390	412	0.96
4	10	0.45	35	5.4	0.6	1	14	418	431	418	441	0.74
5	10	0.0001	0.0076	16.9	1.3	1	23	449	472	449	472	0.96
6	10	0.17	13	6.7	0.4	3	23	480	501	478	501	0.92
7	10	0.53	40	5.2	0.2	2	23	513	535	512	535	0.93
8	10	0.0085	0.65	10.8	4.1	1	23	542	565	542	565	0.93
9	10	5.6e-07	4.3e-05	23.9	1.4	1	23	571	593	571	593	0.98
10	10	0.043	3.3	8.6	3.3	1	23	599	622	599	622	0.97

Sequence Information

Coding Sequence: ATGGATCAAACAGTGCCTGAGACTTGCATACTCTGTCTGGAGGACAATCCTCTGACTCTGGAGCAATATGTGGATATTTACTCCGCAAAGGGAGAGGAACTGAATGTGGTGGAGATAATCAACAAACACTTGCCAATACAGTTAGCTCCAAGCAATGCGAAAGCTCGTAAAGTATGCTCGCAATGCTGGAAAACAGTTTCCGCTTTCCACGCGCTTTATGACTTTGTTAGCACTGCGCAGAGTTCGTTGCGTGGTGAGACGAAAGTGTTGCTgatggaggaggaggaggaggatgatcCGTTGACACAGGGAAACTTCAGTGAAACAACTGCCAAACAGTGTCCAGATAATGCAAATCAAGAACTTAATGGTCGCAATTTCTTCTATCCTGAGGTTAAGATTGAGGAGCACGAGTTGGAACAGTTGCCCAAGATTGAGGTGCTTGAAAGTACAACAAACCTGGATCCATCACCGGCAAGACGTTTACGAAAGCGCTTCAAGGCAGAAGTTGAAACTCCAAATTCCAGCGAATTGGTTAATAATGAAACTCCCGCTGAAGCTGCGCCAAAGAAACGTCGCGGAAGACCAAGAAAAACTGAAGTCCTCAAGGAAGTCCCTGAAGAAATCTCTCAAGTCAATACATCCAATGAGCTAGCTGCAGATTTAAAAACGGAAAATCCTGCTGATGAGCAGATTAGCGATGATGATCATGAATTCATCTGCAATTTCGAGGAAGCTGGCGATCGCAGTGATGACAGCAGCGATACCCTGGACTCCCCAGAAAGCGATGATGATTCCGACTTTGACTTTAAAGTTGACAGGCCAAGCGAAGTAGCGTTTGCTGTGATACCAAAGCGAACTCCAGTGCGGCCCAAGAAATACAAGAAGCGAGCGAAACCCACAGAACCGAAAGTACGCATGTCTCGGGAACTATTGGATCAGCGCAAGAAGCAGCAAGAGGAATATGATGGAATCATTGCCAAGTTCTTCAGTGATGTGCTGCCCTGCTCCATATGCAACTTGTTGGTGCATAACTTTACGGAAATGCAACGCCATCATCGCCTCACACATCAGGTTGATCCAGGCTATATGATCTGCTGTGGTCGCAAGTTTACCCAACGTAAAGTGCTCGCTGAACATGTGCTGGTACACTGGAATCCCGAGCACTTTAAATGTATAACATGCGAGAAGGCATTCCAAAACTCACGGCATCTAGAGTCACATCAACAGGTGCATGTATCAAAGATTTCCTTTCAGTGCGATCTATGCTCTAAGGTATTCCTCAGCAAGACGGCTATTGACTATCATAAGCTCAACAAACATGTGCCCAAATCAGAGTTCAAGTTCGCATGCACCGAGTGCGGcaaaaaATTCCTGACTGAGCGGAAACTCAAAAACCACATGAATTCAATGCACGATCCGGAAAGCATCATTATTTGCGACAAATGTGGCAAACAGATGCGTACCAAGATCATTTTAAAGAAACATCAGGAACTTATGCATTCAAACACACCGCGCCCAGAGCCCGAATTGAAGCAGTGCCAAATCTGCGGTGCCTGGCTTAAGGGCATGACTGGACTAAAGCAGCACATGAAGAGCATTCATGTGGAAAGTGCAGGAGAACATCGTTGTCATGTTTGCAGCAAGATTTCACCAAATGCTCGTGCCCTACGTCGACATATCTATCACAATCACGAATGCGAGCGCAAGTTCAAGTGTACCATGTGTGATAAGGCTTTTAAACGACCCCAAGAACTAAAGgaacacacatccacacacacaggcGAAGTGTTGTACACTTGTCCAAATTGCCCGATGACATTCTTCTGCAGCGCCAATATGTACAAGCATCGACAACGCTTACATCGTGCTCAATATATGGCAGACAAGAATCAGCCAAAGCCTCCAAATATATTGCAACAGGCGGTAGGTGCAACGGCGGCCATGAAAATCAAACTAATGCAAAACTCGAGTGCAGCTAGCATAGAATCCGACTTGAAGCATTTCTAG
Protein Sequence: MDQTVPETCILCLEDNPLTLEQYVDIYSAKGEELNVVEIINKHLPIQLAPSNAKARKVCSQCWKTVSAFHALYDFVSTAQSSLRGETKVLLMEEEEEDDPLTQGNFSETTAKQCPDNANQELNGRNFFYPEVKIEEHELEQLPKIEVLESTTNLDPSPARRLRKRFKAEVETPNSSELVNNETPAEAAPKKRRGRPRKTEVLKEVPEEISQVNTSNELAADLKTENPADEQISDDDHEFICNFEEAGDRSDDSSDTLDSPESDDDSDFDFKVDRPSEVAFAVIPKRTPVRPKKYKKRAKPTEPKVRMSRELLDQRKKQQEEYDGIIAKFFSDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYMICCGRKFTQRKVLAEHVLVHWNPEHFKCITCEKAFQNSRHLESHQQVHVSKISFQCDLCSKVFLSKTAIDYHKLNKHVPKSEFKFACTECGKKFLTERKLKNHMNSMHDPESIIICDKCGKQMRTKIILKKHQELMHSNTPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHVCSKISPNARALRRHIYHNHECERKFKCTMCDKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYMADKNQPKPPNILQQAVGATAAMKIKLMQNSSAASIESDLKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586244;
90% Identity: iTF_00583991;
80% Identity: -