Basic Information

Insect: Drosophila testacea
Gene Symbol: pita
Assembly: GCA_035043265.1
Location: JAWNND010000858.1:369393-371557[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.011 0.88 10.4 0.2 1 23 247 269 247 269 0.91

2 9 7.6e-06 0.00058 20.4 3.3 1 23 275 297 275 297 0.94

3 9 7.6e-05 0.0058 17.2 1.9 1 23 303 325 303 325 0.99

4 9 0.00049 0.037 14.7 0.2 1 23 331 353 331 353 0.96

5 9 4.8e-05 0.0037 17.9 0.3 1 23 359 381 359 381 0.95

6 9 1.1e-05 0.00087 19.8 0.2 1 23 387 409 387 409 0.97

7 9 0.0015 0.12 13.1 5.8 1 23 415 437 415 437 0.98

8 9 0.0019 0.14 12.9 0.0 2 23 473 494 472 494 0.96

9 9 0.012 0.95 10.3 0.6 1 23 500 523 500 523 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.011	0.88	10.4	0.2	1	23	247	269	247	269	0.91
2	9	7.6e-06	0.00058	20.4	3.3	1	23	275	297	275	297	0.94
3	9	7.6e-05	0.0058	17.2	1.9	1	23	303	325	303	325	0.99
4	9	0.00049	0.037	14.7	0.2	1	23	331	353	331	353	0.96
5	9	4.8e-05	0.0037	17.9	0.3	1	23	359	381	359	381	0.95
6	9	1.1e-05	0.00087	19.8	0.2	1	23	387	409	387	409	0.97
7	9	0.0015	0.12	13.1	5.8	1	23	415	437	415	437	0.98
8	9	0.0019	0.14	12.9	0.0	2	23	473	494	472	494	0.96
9	9	0.012	0.95	10.3	0.6	1	23	500	523	500	523	0.91

Sequence Information

Coding Sequence: ATGAATGCATGCAGCGTTGCCACCGCGTTCACGGTGAACAGCAATGATGGCATGCCccgttttatttgtttggatTGTCGACTGCTTTTCGAGCATTGCTACCGCTTCAAGCAGATGTGCAAAAATGCGGAGACACTCTTACGACAATATCCACTTACTGGAAAGTGGCCAGAGCCTTTGGAGAAGCCACGGGCTCCTTTGGTGGCCAATCAAGCGATTAAGAAGGAGGTGCCGACTGAAGTGCAGCCCAAGAAACTACTGAATTCAATGGCCAAGTCCAACAATGTGACAATTGAAAGTGTGCAGGTCTTGGAAACCAGCGCATTGACCAGAAAACTCCTCAATGTGGCTGCTGTGAGCACGGCGGAGCCACCTGTTCCTCCACGGTCATCGGCAGCAAAACGTCCTCATTCGCATTCTTATCAGGTAAAGTTGGAGAACAACCAGGAACTTTCTATGGATGATGTGCACAATTTGATAGCTGACATGGAGGAACTTGACAATTCAACGACATCGCCTTCAAAGTCAGTGTCTGGGAAACCAAAGGTACTCAACAAATCTTCGATGCGTCTACTGAACAAAGGCAGCACTGCGTCGGTGGAGCCACGTCTTGCTACTCCTCAGATAAAGCACTACGAGGATGGAAATGTGGCTCTTGTAACTGAAATTCTCGATCCCAATGAAATTGATGCGGCTGCAGATCCTGTAAAAAATACAGCACCTGTGGCAACTAATGTGTTTCCTTGTCCCCATTGCGAAAGATCATTTCCACTGATGCAGCTGCTGGACATACATCTGGTTAACCACACACGTGAACGAAGTTTCCAATGCAAAGAGTGTGACAAGAGCTTCTTTTCCAAATACGATCTGCAGAAGCATAACTTTATACATACCGGTGAGCGTCCCTACAAGTGTAGTGTTTGCTCCTCTGCCTTCACTCGTCGAGCCTTGTTGCACCGTCATGAACGTGTTCACACGGATGTGCCCAAGTTTATTTGTCTCTACTGTGAAAAGCCGTTTATCTCTCGGGAGGAAATGGAGAAGCACGCAGAGCGGCATACAAAGAAGCGACCTTTCCAGTGTGGCATATGCCAAAAGTCGTTTGCCTTCAAGCAAGGATTGGAACGACACGAGGTTATTCACAGCTCAAATTTGCCCTTCCCTTGCCAATACTGTAGTCGCAGCTTTGTGACAGCTGGCAAGTTAGCACGTCATCTCCAGGCACACGCTGGAAAGCGTGCTTATCCCTGCAAATATTGCAACAAATCGTATCTTTTGTCGCATCATCTGTCGCGGCATTTGCGAATGCATAAGCAGGCACCGGCTGCATCATTCATCTGCAGCATTTGCAAGGACACGCATCAAACTTACGATAGTCTGGTGGATCACTCGATGATACACGCCAGTGTCTCGATGGTATGTCCACTGTGCAAGGCGAGCACCGCTGACTATGACAGCTTGGAGTCGCACATGCAAGCTCACAAGGAGAGCGAGAGGCATGCCTGTGAATTTTGCGACTTTATATTCCTTAGTTCAGATCAACTGCAGAAGCATATCGAGGATGATCATGTGGTAGACATGGTGCCTTATCAGAATGAGGGCGAATACGCTGTGAAGGAGGAGTCCGATTTGATGGAGGAACTACTTGGCGAAGAGTCACAGCCATTAAGTGAGTCTCCATCGCCACCTAAAGCTAAAGTACGCAAATTGAATGCAAGCCCAAAAACGGAAGCTACCACAAAAAAAGGAGCTAGTCCAGAGCAGAAGACCATTAAAAAGACGATACCTTCACAGAGTAGTTTAAAGAAAGTTAGCACCTCAAGGTCTAGTGCTGCATCTTCATCCGTCTCCCCTGAAAGCAAACGTCTAACACGCAGTAAAGATATCAAAGATAGGACGTCAAAACCAAGTGATTCGGTTAAAAAAGTGACCAAATCTGTTGAAGATCAGACGAAACTGGGAAGCAAACAAAAGAACGGCAAGATGACAAGAAATCCAAGCTTAAAGTGA
Protein Sequence: MNACSVATAFTVNSNDGMPRFICLDCRLLFEHCYRFKQMCKNAETLLRQYPLTGKWPEPLEKPRAPLVANQAIKKEVPTEVQPKKLLNSMAKSNNVTIESVQVLETSALTRKLLNVAAVSTAEPPVPPRSSAAKRPHSHSYQVKLENNQELSMDDVHNLIADMEELDNSTTSPSKSVSGKPKVLNKSSMRLLNKGSTASVEPRLATPQIKHYEDGNVALVTEILDPNEIDAAADPVKNTAPVATNVFPCPHCERSFPLMQLLDIHLVNHTRERSFQCKECDKSFFSKYDLQKHNFIHTGERPYKCSVCSSAFTRRALLHRHERVHTDVPKFICLYCEKPFISREEMEKHAERHTKKRPFQCGICQKSFAFKQGLERHEVIHSSNLPFPCQYCSRSFVTAGKLARHLQAHAGKRAYPCKYCNKSYLLSHHLSRHLRMHKQAPAASFICSICKDTHQTYDSLVDHSMIHASVSMVCPLCKASTADYDSLESHMQAHKESERHACEFCDFIFLSSDQLQKHIEDDHVVDMVPYQNEGEYAVKEESDLMEELLGEESQPLSESPSPPKAKVRKLNASPKTEATTKKGASPEQKTIKKTIPSQSSLKKVSTSRSSAASSSVSPESKRLTRSKDIKDRTSKPSDSVKKVTKSVEDQTKLGSKQKNGKMTRNPSLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523157;
90% Identity: iTF_00558126;
80% Identity: -