Dtes003736.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila testacea
Gene Symbol
ZNF526
Assembly
GCA_035043265.1
Location
JAWNND010000286.1:33143-35084[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.13 9.9 7.1 0.3 1 21 294 314 294 315 0.95
2 10 3.8e-06 0.00029 21.3 1.3 1 23 323 345 323 345 0.99
3 10 0.0035 0.27 12.0 2.3 1 23 348 371 348 371 0.93
4 10 7.3e-07 5.5e-05 23.6 0.8 2 23 378 399 377 399 0.98
5 10 2.3e-07 1.7e-05 25.2 0.6 1 23 405 427 405 427 0.98
6 10 4.8e-06 0.00037 21.0 0.7 1 23 433 455 433 455 0.99
7 10 0.0005 0.038 14.7 4.0 1 23 461 483 461 483 0.99
8 10 0.00057 0.044 14.5 0.3 1 23 489 511 489 511 0.98
9 10 0.00011 0.0086 16.7 3.7 1 23 517 539 517 539 0.98
10 10 0.00077 0.059 14.1 0.2 1 23 545 567 545 567 0.97

Sequence Information

Coding Sequence
ATGGATGTGGAGAATATTTGTCGCACTTGTTTAGGCCTTTCAGGACCATTTCTGTCCATCTATGATGGCGGGTCACGCTTGGTCGACATGCTGAGCGAATTCACTAGGATGAAGCCGCGTCGCGAGGATAATTTACCAGCCAGAGTCTGCCTCAGTTGCATCAGTGAAATTAATCATTGCTACTCATTTAAGCGCAAATGTGAGAACTCTAATCGAACACTGAGACAGCTGTTGCCCAATGCCCTTCCCGAGGAGCCAGAGTTCGTAGCTACAACAGCCAAGGCTACCACAGATTCATCGGTCCAAACAAACGCTATCACAACATGCTCAACTGAAGTTCAAACCGATGAGGAGACCAGCATAAAGAAGCCACTGACACTCACTGAGGAGCCCGAGGGTGTGGAAGAGTTTGACTATGAATTTACTGATGAGCAGGAGAGCGATGAGACGCCGTCCAAAGACATTATACTGCACATGGAAAAAGACGACATCAAATATGAAACGGAGataatttacaacaaaaacactgGCGAGCTGCACGAACAGCAAGGACAGAAGGAGTACAAATATCGACTTGTCAGCAATGGCATTGGCGACACATATATAGCGACGCCTCCTCAGGTGACAACACGCAACAGTGCTGcaaagttgttgcaacaacaacagcagcagcaggagcaacaacaccagcaacagccacaTGAAGATAAGCAAGAAGAATCACAATCAACGTCCAAGCGCATCACAAGACGTCGCCCTGCAACACAACTGGACGAGGAGCAGCAGAATTCCGCGAAGCAACCAAAAATTAGTATACCCAGCAAATCCATCAATGCCAATGGGGCCCAAACAACAGAGCCAGAAGACCCTAAGGCAAATTTCCATTGCGATCGCTGCAATGCGGGATTTGTCCTGGAGAAATCATTGATTATCCACCGCCGACAAAACGGATGCACCAATCGCAGTTTCAAGTGCAACGAATGCGAGCGAGTTTTTGTCTCATTGAATCATTTGACAGAGCATCAGGCCACACATGCTGCCCACAAGTGTCAGGAATGTGGAGTGCAATGTGAGTCCAAGGAGCAGCTAGGCAGGCACATGGTCCAGACACACAAACGCAATCTACGAAATCAGTGCAACATATGCCAGAAGGTATTTACGATGCTTTCAACGTTACGGGATCACATGCGGATCCACACCGGTGAGAAACCATTTGTGTGCAACGTATGTGGCAAGGGATTTACCCAGAATGCCAATCTTCGTCAGCACAAGCTTAGACATTCGGACATTAAGCGATTCAAGTGCGAGCTGTGTAATAATTCATTTGTGACCAAAGCGGAACTGACATCGCATGCACGAACACACACTGGTGTCAAGCCTTATGAGTGTGATGTGTGCTCCTCCAGATTTACCACCAGTTGCTCATTGGCCAAGCACAAGCGTAAACACACTGGCGAACGACCCTATCCCTGTGATCTGTGTCCCATGCGCTTTACAGCACTCAATGTCCTAAAGAACCATCGTCGTACCCACACGGGAGAACGTCCATTTGTTTGTCCCTTCTGCTCCAAGAGTTTCACACAGCGTGGCGATTGCCAGATGCATCAGCGAACGCATCAGGGGGACAAAATCTACATTTGTCCAGTGTGTAGTGAAGAGTTCAAATCCATGAATGATATGCGATCACATTTGACGATGCATGAGCAGCAGGACAAGAGATTGGTGCACTTCACCCTTCTAAGCAACAAGGAGAACGGAAATGCGTCGTTGGAGGAACGAGACGAGGAGTCAGATACGGCTGACACAGACTTGATGTAG
Protein Sequence
MDVENICRTCLGLSGPFLSIYDGGSRLVDMLSEFTRMKPRREDNLPARVCLSCISEINHCYSFKRKCENSNRTLRQLLPNALPEEPEFVATTAKATTDSSVQTNAITTCSTEVQTDEETSIKKPLTLTEEPEGVEEFDYEFTDEQESDETPSKDIILHMEKDDIKYETEIIYNKNTGELHEQQGQKEYKYRLVSNGIGDTYIATPPQVTTRNSAAKLLQQQQQQQEQQHQQQPHEDKQEESQSTSKRITRRRPATQLDEEQQNSAKQPKISIPSKSINANGAQTTEPEDPKANFHCDRCNAGFVLEKSLIIHRRQNGCTNRSFKCNECERVFVSLNHLTEHQATHAAHKCQECGVQCESKEQLGRHMVQTHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKLRHSDIKRFKCELCNNSFVTKAELTSHARTHTGVKPYECDVCSSRFTTSCSLAKHKRKHTGERPYPCDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKSMNDMRSHLTMHEQQDKRLVHFTLLSNKENGNASLEERDEESDTADTDLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00537661;
90% Identity
iTF_00558072;
80% Identity
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