Basic Information

Insect: Drosophila teissieri
Gene Symbol: ush
Assembly: GCA_016746235.1
Location: CM028594.1:574814-579434[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0047 0.41 11.1 0.0 1 20 246 265 246 267 0.90

2 8 0.079 6.8 7.2 2.4 2 21 359 378 359 379 0.92

3 8 0.13 11 6.5 2.2 2 21 744 763 743 764 0.93

4 8 0.0066 0.57 10.6 0.0 3 21 816 834 814 835 0.91

5 8 0.0043 0.37 11.2 0.0 2 23 900 921 899 921 0.98

6 8 0.0019 0.17 12.3 1.2 1 23 927 949 927 949 0.99

7 8 0.00034 0.029 14.7 1.0 1 23 1000 1023 1000 1023 0.96

8 8 0.3 26 5.4 0.5 2 20 1137 1155 1136 1157 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0047	0.41	11.1	0.0	1	20	246	265	246	267	0.90
2	8	0.079	6.8	7.2	2.4	2	21	359	378	359	379	0.92
3	8	0.13	11	6.5	2.2	2	21	744	763	743	764	0.93
4	8	0.0066	0.57	10.6	0.0	3	21	816	834	814	835	0.91
5	8	0.0043	0.37	11.2	0.0	2	23	900	921	899	921	0.98
6	8	0.0019	0.17	12.3	1.2	1	23	927	949	927	949	0.99
7	8	0.00034	0.029	14.7	1.0	1	23	1000	1023	1000	1023	0.96
8	8	0.3	26	5.4	0.5	2	20	1137	1155	1136	1157	0.91

Sequence Information

Coding Sequence: ATGTTCGCTCCGGTCGAGATGTCGAATTTCTGGCGAAGCGAGATGCAAACTGCAAACTGCGACGCTTATCCGGCGACTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACGTCCACTTCCACTTCCACTGTCCGCCGCCATAATCTCGGCCAGCATCGCCATTCCAAAGATCTGAGCGCTCAGGAAATGGGCGAGCAGAAGCAGCAGCAAATGGAGGACCACCTGGAGGATCAGTTGGACAATTCCAGAGACCCCCAGAACAACAATAACAATATCGACGAAGACGACGATGAAGACGCTGACTTTGAGCAGCCAGAAAACGCCAATCCCCAACAGGATCAGGACTTGGGAGAGACAGAGATGGAGCAGGACCATGATCTGCAGCAGGAGGAGCAGCAGGAACTGCCTGCAAACAGCCCAAGCACTCCGCCCAGGAGTCCCAGCTCTCCCCCGCTGATTCCCAAGCTGGAGCAGCCAGCCACGCCGCCCTCGGAGGCGGAAGCCTCTCCGTGCCCCTCACCCTCGCCATCGCCATCGCCCTCGCCATGTCCCACGCCCAAGTATCCCAAAGTGCGTCTGAATGCGCTCCTGGCCTCAGACCCTGCCCTCAAGCCAGATGCCAAGGAGCTGACTCTGCCGGACGCCCGTCTCCTGGCTCCGCCGCCGCTCGTCAAGCCGGAGACACAGGCGCAACCGGATGTAGCGGAACCTCTGCTGAAGCCAGCCAGATTTATGTGCCTGCCCTGTGGGATCGCATTCAGTTCGCCCTCAACTCTGGAGGCCCATCAAGCCTACTACTGCTCTCATAGGATTAAGGACACGGACGAGGCTGGCAGTGATAAGTCAGGGGCAGGAGGATCGGCAGCCGCAGCTGGCGAGGCAGCGGGACTAGCAGGGGGCTCCTCCGAGCCACCAGCCAAAATGGCCAGGACAGGAAAGCAGTATGGCTGCACCCAGTGCTCCTACAGCGCGGACAAAAGTTTGCCCAGCCTCCTCCAGAACGGAATAGCTCCTCCGGGAGTCACGCCCAATCCGATGGAGGATAGCTCTAGTCAACAAACCGATCGCTACTGCAGCCACTGTGATATCCGGTTCAACAACATCAAGACCTATCGAGCGCACAAACAGCACTACTGCAGTTCGCGGCGACCGGAGGGACAGCTCACGCCCAAGCCAGCCGCTTCTCCAGGAGCAGGATCCGGACCGGGTTCCTCCGGCGCATCCATGGGAGTATCTGCCCAGGCGGCTGCACCCGGCAAGATGAGCCCGCAGGCCAGGAACAAGACCCCGACTCCCGCGATGGTGGCCGTCGCAGCTGCAGCGGCGGCTGCTGCGGCCTCCCTCCAGGCCACGCCTCATTCGCATCCACCTTTCCTGGCCCTGCCCACCCACCCGATCATTATTGTGCCCTGCTCGCTGATCCGTGCAGCCAGCTTCATTCCAGGCCCACTGCCCACACCAAACTCGGGGATCGTGAATCCAGAAACCACCTGTTTTACCGTGGACAACGGGACGATTAAGCCACTGGCCACTGCCCTAATTGGCGCCTCCTTGGAGCCCGAACGCCCTTCAGCTCCATCATCTGCTGCCGAGGCCACAGAAGCCAAGAGCAGTCCTCCAGAGCCCAAGCGAAAAGAAGCAGGGCAAACTAGAGAGTCTGCGCCTCTCGATCTCTCGCTGCGTCGATCGCCCATCACCCTGAACTCGCTGAGCTTGCGGCAGCGCCAACTGCGCAATGCCCTTTTGGATGTGGAGGAAGTACTCCTTGCCGGGGCAGGAACTAGCAAGGAGAATGCGGAGACTCCGAGAGGAGGAGGGAGTGTGACTCCCGAGCAGATCGTTTGCGCTCCCTCCCTGCCGAGCAGTCCTTCGATGAGCCCCTCTCCCAAAAGACGAGCCATCAGTCCACGCAGTTCCGGGGCTGGAAGTGCCTCCTCCATGTCGCCACCTGGTCTCAATGTGGCTGTTCCCCATCTGCTGGACATGCGCTCCATGCTACCCGCGGACTTTGGACTCTCCGAATCGCTGTTGGCCAAGACCAACCCGGAACTGGCTCTGAAACTGGCGGCGGCAGCGGCCGCAGCTGCTGTGGCGGGCAGTAGTGGAGCAGCAGCCTTTCCGCCCTCTCCTCTTCCTGCCCAAGCTAGTAGCGGGAATCCTGGAAGTGGAGGACCGGCAGGTGGCGCCCAGCAGCCTCAGATCTATGTGAAAAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTCTGCAAGTATGAGAACTACCTGGCGCACAAGCAGCATTATTGCTCGGCCAGGAGCCAGGAGGGTGCTAGTGAAGTGGATGTCAAGTCGGCCGTTTCACCATCCATCGCCGGAGCTGGAGGACTGGGAAGCGGAGGGGCAGAAGCTGCTTCGTCTGTGGAAACCACTCCGGTGGCATATCAGCAGTTGATCTGCGCCGCCTGCGGAATTAAGTACACTTCCCTGGACAACCTGCGCGCCCATCAGAACTACTATTGTCCCAAGGGAGGAGCAGCTGCTGCCCCCGCCGCGGCGCCCACTGATCCCGGCCAGCTGGCCATGGCAAAGGAGAAGTGCGGAAAGTGCAAGACACTGCATGAAATTGGCCTGCCTTGTCCACCCCCCGTCGCCAATCACCTCGCAGCGCCACCAGCCAATCCACAACCCGCCTCCAATAGTCTGAACAAGTGTCCCGTTTGCGGGGTGGTGAGTCCCACCGCGGCACTGGCCAAGAAACACATGGAGATGCACGGAACAGTAAAGGCCTACCGCTGCAGCATCTGCCAGTACAAGGGAAACACTCTTCGCGGCATGCGCACCCACATTCGAACCCATTTCGACAAGAAGACTAGCGACGTGAACGAGGAGCTCTACATGACCTGCATCTTTGAGGAGGATGTGACCGCGCTGAGTCAGGAGCTGGTTCCTTCAACGGCGGCATCTGCCACAAGTGTACACGATTCCATGGATCATCCCTCGCAGACGTTCAACTGTGATTACTGCAACTATGTTTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGATGCATCCCCATGTGGCCATCAACTCACCCTCCATTTCCCCCGACACCAGAGACCAGGATGTGAATTCCAACCCCACTCCCAACCAACACTCGAATTCCGATGGATCCAACGGAGAGGCAGCCAGTTTCCACATTAAATCGGAGCCCCTGGATCCACCCCCGACTGTGAATCTGGTGCACGAGAACAACAACTCGCCGATCGCCACGCCACATATTAAGGCTGAGCCAATCGAGGTCGGAGCGGATGCTGCGGCCGGCGGGCTGGTTCCGCCGATGACTTCTCCGCTGGGAAACAGCAGCAGCATGGCTGCCGCAGCAGCTGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCGACCTGTGACATATCCTTCAACTACGTGAAGACCTACCTGGCTCACAAGCAGTTCTACTGCAAAAACAAGCCGATTCGCCCCGAGGCCAGCGACAGCCCCAGTCCGAATCACCTGGGCGGGGGCGTTGCCGTGGGCCTGGGCCTTGGCGGCCTGGTCGGTGGACACGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MFAPVEMSNFWRSEMQTANCDAYPATPSACHVCAMSTSTSTSTSTVRRHNLGQHRHSKDLSAQEMGEQKQQQMEDHLEDQLDNSRDPQNNNNNIDEDDDEDADFEQPENANPQQDQDLGETEMEQDHDLQQEEQQELPANSPSTPPRSPSSPPLIPKLEQPATPPSEAEASPCPSPSPSPSPSPCPTPKYPKVRLNALLASDPALKPDAKELTLPDARLLAPPPLVKPETQAQPDVAEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKDTDEAGSDKSGAGGSAAAAGEAAGLAGGSSEPPAKMARTGKQYGCTQCSYSADKSLPSLLQNGIAPPGVTPNPMEDSSSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPAASPGAGSGPGSSGASMGVSAQAAAPGKMSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALIGASLEPERPSAPSSAAEATEAKSSPPEPKRKEAGQTRESAPLDLSLRRSPITLNSLSLRQRQLRNALLDVEEVLLAGAGTSKENAETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPSPLPAQASSGNPGSGGPAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDVKSAVSPSIAGAGGLGSGGAEAASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAAAPAAAPTDPGQLAMAKEKCGKCKTLHEIGLPCPPPVANHLAAPPANPQPASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEELYMTCIFEEDVTALSQELVPSTAASATSVHDSMDHPSQTFNCDYCNYVSTYKGNVLRHMKLMHPHVAINSPSISPDTRDQDVNSNPTPNQHSNSDGSNGEAASFHIKSEPLDPPPTVNLVHENNNSPIATPHIKAEPIEVGADAAAGGLVPPMTSPLGNSSSMAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGVAVGLGLGGLVGGHGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00543306;
80% Identity: -