Basic Information

Insect: Drosophila tanythrix
Gene Symbol: BCL11A
Assembly: GCA_035043275.1
Location: JAWNNC010000508.1:2305595-2315361[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.028 2 9.2 2.4 1 23 309 332 309 332 0.95

2 6 1.1e-06 7.7e-05 23.1 1.6 1 23 776 798 776 798 0.98

3 6 0.013 0.92 10.2 4.7 1 23 804 826 804 826 0.99

4 6 1.2e-06 8.6e-05 22.9 3.2 2 23 1103 1124 1102 1124 0.97

5 6 1.6e-05 0.0011 19.4 3.3 1 23 1130 1152 1130 1152 0.99

6 6 2.9e-05 0.0021 18.6 0.4 1 22 1160 1181 1160 1181 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.028	2	9.2	2.4	1	23	309	332	309	332	0.95
2	6	1.1e-06	7.7e-05	23.1	1.6	1	23	776	798	776	798	0.98
3	6	0.013	0.92	10.2	4.7	1	23	804	826	804	826	0.99
4	6	1.2e-06	8.6e-05	22.9	3.2	2	23	1103	1124	1102	1124	0.97
5	6	1.6e-05	0.0011	19.4	3.3	1	23	1130	1152	1130	1152	0.99
6	6	2.9e-05	0.0021	18.6	0.4	1	22	1160	1181	1160	1181	0.97

Sequence Information

Coding Sequence: ATGGAGCTGTTCGTTAGCTGTGCAGGTGGTGTCCCAGTTACAGTTACTAATCATGAGCATTCTCACATTGCAGATTCCGACTCGACAGAGAACGATGCGGTCGCAGCGCAGGACATCCTCACGTGTGGCGCCTGCCAGAAGACCTTCGCACTGTCGGACATTGTCCGCTTCATTCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGTCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGTCGACCACTCAGTCTGGTCAATCGCCGTCCATCAATTTCGGCGCCAATCACAGGCCGTAAATCGGCGCCAGTTGCTGGCAGTGGTGCCACAGTTGCTGCCAATGCAATTGCCAGTGcggctgctgccactgctgccgctgcagcggcggcaacagcagcggctgcCGCAGCCGCAGTTGCAAGCAGCGCTGCAAGCGGctcacgcatacacacaccgCCGCCGAGTCCAGCGGATCTGCTCGCCGATGGCGCCAGCAGCACTCCCAAACGCCTCGTCGATGAGAATGACAATACGACGCCCAAGGCGGACAGTGATGCGCTGACCACCGCCACAGGCGCAGCGGGACTGGAGTCGAGCATCGCTCACAGTCCACGCGCACAGTTGGCGCAGGGGCAGCTGATTGGTCGCGAGGAGTGTGCTCTGCACGATGACAAGCCAAAGGTCAAGCAGGAGCCCTATGCCGACGACGAGCAGCTCGACGAGGAACTGCATCTGGAGCAGGCTCccgagcaggagcaggagcggGAGCAGGAACGGGAACTGAATGCGCAACTGCTGACACAGGCGACCGACAGAGACGAGTGCCAACAGCCGCTGGCCAAGCGACCCAAAATGGAGCTCGTCGATGCCGAGGCGAACACAGTGCACACAGAACCCAGCAATTACACATGTTCGACGTGCAAGACCCGTTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATTTACGTGGAGACGGGCGGCTGTGGCGCCACCTTGACTGTGGCCACACCCGCCGCTCTTAATgctgcggcaacagcagcagcagcacaagccaCCGGCGTCAGCGTCAGTCCAAATCGTTGTCCCAGTcccgcagcagcaactgttggtAGCGTCTCCCTGTCGTTGCCGCTGCACGCGCTAATGGCGCAGTCACCGGCGCCTaagcggagcagcagcaacagcagcgccgccgccgcagcagcagcagcagccgcaattTCTGCAGGCTCGGCCAatacgagcagcagcagcagcagcaatgtcagcagcagtagcaacaacgcCAATTCACCCacacagcaactgttgcagcagcgtgtacatcagcaacagcaacaacagcagcagcaacagcaacaacaacagcagcagcagcagcaacagcagcagcaacagagtcTAGTGCTGGCAGCAGGCATGCGTCATCATGCGCTTCTGGCGCCACCAGATTCGCTGCATGCGAACCCCTTCCAGCTGCTGCGCATGCCACTGCCACCTGCGCTGTCGCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTGTTTGGTCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTTAGCGAGCAGTTCCGGCATCATGGCTTCAGTCtggccgccgccgctgccgccgcccaGGCGCAATTCAATGccaacacacagcaacaacagcagcagcagcagctgcaacctGCTCAGCCCATTGCTGTCAATGTTCCTAATCCCGTCGAGCAGCGACCGCCATCGAGCAATAGCAGCCAGCGTGGCTCAGTACCGCCCGCTGCACTGCCGCCTCCGTCGCTCAgctcacagcagcaacagcaacaacaacagcagcagcaacagcagcaacagcagcagcaacagcagcaacaacagcaacaacagcaacaacaacaacagcagcagcagcagcaacaagtggctgcagcggctgctgctgctgcagctgcactgaGTCCAGCTGCTAGTCTAAATTTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAACAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCTGCCGCGCTTTCGGTTGCCGCTGCAACAACGCCGCCAGAGAAAGGTATCGAGAATGGACAGGTTACATCGACGCCCCGTTCCGCCAGCACGCCCACACCCACCAAGCCAGATACGGAACGGGAATCCGAGCTGGAATCGAGCTGCTTTTCGTGCGGCTACTGCGACAAGAAGTTCCGCTATGAGAACAACTTGATTATCCACCAGCGGACGCACACCGGCGAGAAGCCGTATAAGTGCACCGCCTGCGATTTTGAGTGCTCGCACATACAGAAGCTAATGAAGCATATGCGGGTGCATCGCAGTCCAGCCGATCAGGGACACGATGGTGGCGATAATCAGGATGGTCACGATGGCGGCAGCAATGCCGATTCGCTGGAAACGAATGAGGCGGACAACGATGACGATCCCAATCCCGATGAGTCCGACGAAGAACTAAACGACGAGGATGCCGACGCGGATGCCGATGGCGAGGATGATGACGAGGATGAGCTAGACGATTGCGATGATGTTGACTACGAGGCCGAAGATCTGAGCGTCAACAATCGCATTGATGGCAAAAGTCAAAGCCCCAAGACGACCAGCTCCGGTGCCACATCGCTGGTGGGTGAGCTGATGGACAAGTTCGGGCTCTCCAATATTGCCCAATATTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCCGGACGCAAGGAAGCAGccgctgtggcagctgccgctgctgcggccGCCGCTGttgtcgacaacaacaatcgcgGTTCGGCGGCCGGTGTGGCTAATCCAGGCGCTGGCAGCGGCGTCGCCTCCACCCAGCCACTGGGTGACAAGCTTAACGGTTTGCCGGTGGCAGCGTTGCGACTACGCGATGAATTCGCCAAGAACTGTAATATGTTCCAACCACAGCCGCAGGATGCGCCGTCGCAGGTGCCGCTCTTCAATCCGTTTCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAGATCGATGGCGGTGATTGGTGGGGCATGTCCGCCCTGCATCGTAACGAGGCGCTCTTCGAGAACCTCAAGCTGAAGCCGTTGGGTTTGGGCGGTGCGAATTCGCTGTTGCAAGGACCGCTGCTCAAAAAGGAGAGCCGGCAGCGCAACGATACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGTTCCAATCTAACGGTGCATCGTCGCAGCCACACCGGCGAGAAGCCATACAAGTGTGAACTGTGCTCCTATGCTTGCGCCCAGAGCTCCAAGCTCACGCGCCATATGAAGACGCACGGGCGCACCGGTAAGGATGTGTATCGCTGTCGTTTCTGCGACATGCCCTTTAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAaggcggctgcagctgctgcaaatgcagccAATGCAGTTGCCGCTGCCCAAGCCGCCGCTGCCGCACAGCAACTGCAGGCTGCTGCTCaggcacagcaacagcagcagcagcagcaacagcagcaacaacagcagcaacagttgccatcGCAATCGCAGCTATCGCCGCCTTGTGCAATGGGGGTGGCAGTCGGCTATCCGCCGCAATTCGGACATAATCTGTCGCTGGCGGGCAGCGTGAGTGGCGACAATGATTCGAATGCATCCTCCAGCCTGCCAGCGCACTCCTCCATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MELFVSCAGGVPVTVTNHEHSHIADSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVAGSGATVAANAIASAAAATAAAAAAATAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSDALTTATGAAGLESSIAHSPRAQLAQGQLIGREECALHDDKPKVKQEPYADDEQLDEELHLEQAPEQEQEREQERELNAQLLTQATDRDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVETGGCGATLTVATPAALNAAATAAAAQATGVSVSPNRCPSPAAATVGSVSLSLPLHALMAQSPAPKRSSSNSSAAAAAAAAAAISAGSANTSSSSSSNVSSSSNNANSPTQQLLQQRVHQQQQQQQQQQQQQQQQQQQQQQQQSLVLAAGMRHHALLAPPDSLHANPFQLLRMPLPPALSQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFSLAAAAAAAQAQFNANTQQQQQQQQLQPAQPIAVNVPNPVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAAAAAAALSPAASLNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAALSVAAATTPPEKGIENGQVTSTPRSASTPTPTKPDTERESELESSCFSCGYCDKKFRYENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADQGHDGGDNQDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDADADADGEDDDEDELDDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVVDNNNRGSAAGVANPGAGSGVASTQPLGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPSQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQLPSQSQLSPPCAMGVAVGYPPQFGHNLSLAGSVSGDNDSNASSSLPAHSSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00616427;
90% Identity: iTF_00558986;
80% Identity: -