Dtan007954.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tanythrix
Gene Symbol
-
Assembly
GCA_035043275.1
Location
JAWNNC010000508.1:19713097-19716461[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0079 0.55 10.9 0.6 2 23 126 148 125 148 0.90
2 11 0.38 26 5.6 8.8 2 23 440 461 440 461 0.97
3 11 1.3e-06 8.8e-05 22.9 2.8 1 23 467 490 467 490 0.96
4 11 0.00057 0.04 14.5 0.7 1 23 495 518 495 518 0.96
5 11 6.5e-05 0.0045 17.5 5.5 1 23 536 558 536 558 0.96
6 11 0.00013 0.0091 16.5 1.6 1 23 563 585 563 585 0.98
7 11 3.4e-05 0.0024 18.4 1.7 1 23 591 613 591 613 0.95
8 11 2.4e-05 0.0017 18.8 0.7 1 23 619 641 619 641 0.98
9 11 3.5e-07 2.5e-05 24.6 2.7 3 23 649 669 648 669 0.99
10 11 2.4e-08 1.7e-06 28.3 1.0 1 23 675 697 675 697 0.99
11 11 1.8 1.2e+02 3.5 5.3 1 19 702 720 702 725 0.88

Sequence Information

Coding Sequence
ATGCCAGACACTTATGGTCAGTTCGATGCCGATCGCGTCTGTCGTGTTTGCCTGCGCGAAGTGGGCGATTTTTACTTTATCTACGATGAAGCACCAGTGGAGCAGGCGTTACGACAAATGCCGCATCACATGTGTGACACCTGCATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCGGGACGCTGAAAAGGCATATCGCTCGCTTGTGGACATACTGGGCCGCACACCCGTTAGCAAGCCGAACAGTAGCGATATGTGCACCCAGACCGAACAGCTTCCCATGCTGCCGTGCGGCATCTGCAACGATAAGTTCTTAAGCATTATTGAAGTGCGTCTGCATCGGAATCGCCAGCACAAGAACATGTCGGAGCTCAAGTGCAAACTGTGCGACGAACAGTTCCAGCAATTGCGCCAGTTGCTTAACCATCTCGTGGAGCGACATGATCCCAAGTCGGCCACATCGTTTTTGCGTCGCCGTCGCGAATGCTGTGCACAATGTGGAGGGCCGGGGCCGGGTCGGCGCCGGACGCTGGCCGCGGAGCAGGAGGTGCAATCTGAAACGTGGCCGCCTATCGACGAGGCAACCATGCACAGCGCCGACGAATTGGTTTCGGCTGCCGTCTTATTTAATGATCCAGCTGCGTGCTCCGATGACGAGAACGACAACGATAATAACGAGATGGGCTATCAATGCCATACGAATCCCATATCAAGCAACGAGGACACTGAAGATGGAGAGATCCATGCGGAAGCTAAGCAATCCCTGTGGCTGCACATCAAGCCAGAGCCGGAGGCGGACCTCGATCCATATCCGGAGTCATTTGTGGCACCTGCAAATCGCGTGATGCGccgcaaaaaaacaaatctagAACGTGTCCAGACTGGCACAGAGGACGAGAATCAAGGCCTGAACAACCAGAAAAATGTTACCAGTGTTTTGGCAGCAGAGGTTAAAGAGGAGCCACTGGTCACCGGCAGCGAGCAAGAGTTACCGATTAAGCTGGAACGCCAGCGGTCTGATAGCGTCAATGAGGATGGTGAGTATGAGATAGACGCCGCATCAGCCAACATTTATCACAGCGCAGATGAGGAGGACGGCGAAGAAGAGTTTGTCAATGACGAGAGTGACATTGATGAATACGACGACGAAGATGAGGATGAACCGGATGCCGAGCAAAAGCCGCAATCTGAGGACAAGGCCAAGCAGACCCAAGTGAAAACTGTGCGCGATTATCTGCAGAAGCCGACAGCTGGCAAGCAGCGACGTCGTCGCCGCAAAAAGCAAAGTGATCCGGCGGCACCGAATCCGGAGAACCGATGCGATGTCTGCATGCGCACATTTTCCCGCCACTGTCATTTGTTGCGCCACAAATTGTCGCATTTGGAAAAGAAGCCGCACAGCTGTCCGCACTGTCCCAAGGCGTTTGCGCGCAGCGATCATTTGAAGGCGCACGTGCAGAGTCTGCATGGCAACAAGGAGCACAAGTGCGTGCTGTGCGAGGCAGCGTTTTCCCGCCTCGATGCCCTCGAGCGGCACAAGATGAGCAAGCACAACGGCGAGGGCCTGGACGCCAGCAGCGAGCTCAAACTTCAGATGAGCGAGCATACGTGCGAGTACTGCTCCAAGCGATTCTCAAGCAAGACCTACCTGCGCAAGCACACGCTGCTCCACACGGACTTCCTTTACGCGTGCAAGAGCTGCGACGAGACATTCAAGGAGCGCCAGCAGCTGCGCAGCCACGAAAAGACGCACACTGGACAACGCAATTTCCTCTGCTGCATTTGCGGCGACAGTTTTGCGCGCAACGATTATCTGCGTGTCCACATGCGGCGACACAATGGCGAAAAGCCATACAAGTGCCGTTATTGCGTCAAGGCCTTTCCACGCGCCACGGATCTCAAGGTACATGAGCGATATCACACCGGCACAAAGCCCAACCTGTGCAATACTTGCGGCAAGAGTTTCCATCGCGCATACAATCTGACCATACACATGCGCACCCATACTGGCGAGCGTCCGTACAAGTGTGACCAGTGCCCGAAGAGCTTCAGCCAGAGCAACGACTTGAAGGCGCATATACGACGGCATACCGGGGAGCGCTACAAGTGCCCGCATTGCGATGCCTACTTTCTGCAGCTTTACCATATGCGCAACCATTGCCTCAGTGTCCATAACAAGCATATTGAGACGAAAACTGGTCGGCTACAGCGCACTGGTCTGTTGGACGAGTCTAATCACACGCATCTTACCACTGTGGTCATGCCCGCAACACGTTCGCATCCATCAACGGCAGATCCGTCAGCGATAGTTAGCACACAATTGCCCGCATCGTCGACAGCGCCTGCGACAATTGCAACGCCAATTATGCATTCCCCGGTGACATACAATATAGCATCACCAGCATCAGGGTCGGTGCCAGTGCCGGAAGTCGCCGGATTTGTGGGTGTAGCGAACAATGCAAGGGCGACGTCAACGGCAACGACAGCGACATCCTTTGGGGCATTTAATATACCTCCCGTGATTATGGCGCACTTAATGTACAATCATAGCGGCAACAGTCAGCAGAACAATGCCAGCGGCAACGAGACCGGAAAATAA
Protein Sequence
MPDTYGQFDADRVCRVCLREVGDFYFIYDEAPVEQALRQMPHHMCDTCIKAACQAYRFKRDAEKAYRSLVDILGRTPVSKPNSSDMCTQTEQLPMLPCGICNDKFLSIIEVRLHRNRQHKNMSELKCKLCDEQFQQLRQLLNHLVERHDPKSATSFLRRRRECCAQCGGPGPGRRRTLAAEQEVQSETWPPIDEATMHSADELVSAAVLFNDPAACSDDENDNDNNEMGYQCHTNPISSNEDTEDGEIHAEAKQSLWLHIKPEPEADLDPYPESFVAPANRVMRRKKTNLERVQTGTEDENQGLNNQKNVTSVLAAEVKEEPLVTGSEQELPIKLERQRSDSVNEDGEYEIDAASANIYHSADEEDGEEEFVNDESDIDEYDDEDEDEPDAEQKPQSEDKAKQTQVKTVRDYLQKPTAGKQRRRRRKKQSDPAAPNPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCEAAFSRLDALERHKMSKHNGEGLDASSELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSVHNKHIETKTGRLQRTGLLDESNHTHLTTVVMPATRSHPSTADPSAIVSTQLPASSTAPATIATPIMHSPVTYNIASPASGSVPVPEVAGFVGVANNARATSTATTATSFGAFNIPPVIMAHLMYNHSGNSQQNNASGNETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00620004;
90% Identity
iTF_00511432;
80% Identity
-