Basic Information

Insect: Drosophila tanythrix
Gene Symbol: kipf
Assembly: GCA_035043275.1
Location: JAWNNC010000351.1:9886504-9888066[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00014 0.01 16.4 5.5 1 23 216 238 216 238 0.95

2 10 1.3e-05 0.00092 19.7 3.1 1 23 244 266 244 266 0.99

3 10 4.1e-07 2.9e-05 24.4 0.4 1 23 272 294 272 294 0.98

4 10 4.2e-06 0.00029 21.2 2.3 1 23 300 322 300 322 0.98

5 10 3.1e-07 2.2e-05 24.8 1.0 1 23 328 350 328 350 0.99

6 10 2.3e-06 0.00016 22.1 4.7 1 23 356 378 356 378 0.98

7 10 2.5e-06 0.00018 21.9 1.0 1 23 384 406 384 406 0.99

8 10 7e-06 0.00049 20.5 4.7 1 23 412 434 412 434 0.98

9 10 2.7e-05 0.0019 18.7 0.1 1 23 440 462 440 462 0.98

10 10 0.07 4.9 7.9 0.4 1 11 468 478 468 480 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00014	0.01	16.4	5.5	1	23	216	238	216	238	0.95
2	10	1.3e-05	0.00092	19.7	3.1	1	23	244	266	244	266	0.99
3	10	4.1e-07	2.9e-05	24.4	0.4	1	23	272	294	272	294	0.98
4	10	4.2e-06	0.00029	21.2	2.3	1	23	300	322	300	322	0.98
5	10	3.1e-07	2.2e-05	24.8	1.0	1	23	328	350	328	350	0.99
6	10	2.3e-06	0.00016	22.1	4.7	1	23	356	378	356	378	0.98
7	10	2.5e-06	0.00018	21.9	1.0	1	23	384	406	384	406	0.99
8	10	7e-06	0.00049	20.5	4.7	1	23	412	434	412	434	0.98
9	10	2.7e-05	0.0019	18.7	0.1	1	23	440	462	440	462	0.98
10	10	0.07	4.9	7.9	0.4	1	11	468	478	468	480	0.93

Sequence Information

Coding Sequence: ATGGAGCAAATTTGCCGTGCATGCAAAATCAGCTCCTGCAGCCTGGTGAATATATTCACAGAGGGGCAGCCCAGTCTGGCAGAGATGTTGAGCGAGAGCGCTGCCTGTGAAATCAATCGAAATGATGCACTTCCTCAGCAGCTGTGCCACTCCTGCGTCATCGCTGTACAAAATGCGTTTCGATTGAAGTGCAACTGCAGacagaaagaaacaaaaacagatgTTTGccgcatttgcagcagcagctcaactaCGCTAATTAAGATCAATGCCAAGCGGCAGCAGCCACGGGACGAACCTAGTCTAGCGGAAATGATAAAAGAGTGCATTAACTGTCGGACAAATCCCAGGGATCAGATATGCCTGACCTGCATTCTGAGTGTTGTAAACGCTTTTCAATTCAAGCGCAGATGTGAGCAGAGTCAGAAGCAGATTAAAGCTGAAATTCAAGAAAGTGATGCAGTTGAACATGTGCTGTCCGAGAACAGCTTAGAAATGGACCAACAAGAATATAGCATTAAAATCGAAGTCACCGAAAATGAAGAAGACTTTGAATGCGAGGAGACTCACATTATGTTGGAGGAGTCGAATACGcctgttaataataatatcctAGCAGAGATTGAAGTGGATGCAAAGAAGAAACACGCGTGTGAGAAGTGTGGCAAACGGTTTTCGAACACTTGTAACCTTCTCGTGCACAGACGCTTCCATTCCGGGGAACGTCCGTTCAAGTGTTGCGAGTGTCCAAAGGATTTCACAAGTCGCAAAGTTCTTAAGGATCACATGCGCATCCACACCGGCGAACGGCCATTTCAGTGTGACCAGTGCCCCAAGGCCTTTGGCCGCAATAGTGCTCTGGTTAAGCACATGTTCACGCATACGGGCGAACGGCCCTTCAAGTGCAGCCAATGCCCTAAAGCCTTCTATCAGAGTGGACATTTGAAGATCCATAATCGCATTCATACTGGGGAGCAACCATACAAGTGTCCCCATTGCCCCCGGGCCTTTCCACGCAAGGAGTATCTAGTGACGCACCTGCGACTGCATACGGGCGAGCATCCACACCAGTGTCCCCACTGTCCCAAGTACTTTTCCCGTAGCAAAAACTTGGAGATGCACTTGACCACGCATACGGGTCAGCAACCCTATCGGTGTCCCCATTGCATCAAGGCGTTCACCGCCAATTCCAATCTACAAATCCATATCCGGAGTCATACGGGCGAACGTCCGCACAAGTGTCCCCATTGTGCGAAGGCATTCAGCCAGAGCGTCTGCCTCCAGAATCACATACGCATCCACACCGGCGAACGGCCGTTCCAATGTGCCCAATGCCCCAAGGCTTTCGCCAGCAAGGGGGGATTGTACAATCACAGTCGTGTCCACTCCGGCGAACGTCCCTTCCAGTGTCCCCAGTGCCCGAAAAATTTCCGCGCAACGAGAACCTGCGCAATCACATTGCCTCCATTCCGAGGATCGACCGTACAAGTGCATAATGTGTCCCAAGGACTTTACCCGGCGCGAGAGTCTGGCCCGGCACAAGCTGATTCATGCCAAAAATGA
Protein Sequence: MEQICRACKISSCSLVNIFTEGQPSLAEMLSESAACEINRNDALPQQLCHSCVIAVQNAFRLKCNCRQKETKTDVCRICSSSSTTLIKINAKRQQPRDEPSLAEMIKECINCRTNPRDQICLTCILSVVNAFQFKRRCEQSQKQIKAEIQESDAVEHVLSENSLEMDQQEYSIKIEVTENEEDFECEETHIMLEESNTPVNNNILAEIEVDAKKKHACEKCGKRFSNTCNLLVHRRFHSGERPFKCCECPKDFTSRKVLKDHMRIHTGERPFQCDQCPKAFGRNSALVKHMFTHTGERPFKCSQCPKAFYQSGHLKIHNRIHTGEQPYKCPHCPRAFPRKEYLVTHLRLHTGEHPHQCPHCPKYFSRSKNLEMHLTTHTGQQPYRCPHCIKAFTANSNLQIHIRSHTGERPHKCPHCAKAFSQSVCLQNHIRIHTGERPFQCAQCPKAFASKGGLYNHSRVHSGERPFQCPQCPKNFRATRTCAITLPPFRGSTVQVHNVSQGLYPARESGPAQADSCQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558881;
90% Identity: iTF_00610044;
80% Identity: -