Basic Information

Insect: Drosophila tanythrix
Gene Symbol: -
Assembly: GCA_035043275.1
Location: JAWNNC010000522.1:4390115-4394656[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00055 0.038 14.6 0.9 1 23 214 236 214 236 0.97

2 25 0.55 39 5.1 0.4 2 10 243 251 242 256 0.86

3 25 0.012 0.82 10.4 0.9 2 23 281 302 280 302 0.96

4 25 0.00064 0.045 14.4 0.7 1 23 377 400 377 400 0.94

5 25 2 1.4e+02 3.4 0.7 2 22 410 430 410 430 0.95

6 25 2.6 1.8e+02 3.0 0.8 1 22 439 460 439 463 0.88

7 25 0.0048 0.34 11.6 0.5 1 23 581 604 581 604 0.96

8 25 0.0093 0.65 10.7 0.1 1 22 613 634 613 634 0.95

9 25 0.0033 0.23 12.1 4.3 1 23 643 666 643 666 0.97

10 25 6.8e-05 0.0047 17.4 0.4 2 23 680 701 679 701 0.97

11 25 2.2e-05 0.0015 19.0 5.4 1 23 707 729 707 729 0.98

12 25 0.075 5.3 7.8 0.5 1 23 869 892 869 892 0.95

13 25 0.029 2.1 9.1 2.2 1 22 899 920 899 920 0.95

14 25 0.42 30 5.5 0.4 1 20 929 948 929 952 0.86

15 25 6.2e-05 0.0043 17.6 1.6 1 23 976 998 976 998 0.97

16 25 0.00047 0.033 14.8 0.7 1 23 1005 1027 1005 1027 0.98

17 25 0.13 8.9 7.1 0.0 2 21 1054 1073 1053 1074 0.94

18 25 0.041 2.9 8.7 4.0 1 23 1119 1142 1119 1142 0.96

19 25 0.007 0.49 11.1 1.5 1 23 1179 1202 1179 1202 0.96

20 25 0.015 1 10.1 3.1 1 23 1229 1252 1229 1252 0.97

21 25 1.4e-05 0.00099 19.6 0.1 2 23 1273 1294 1272 1294 0.95

22 25 4.8e-05 0.0034 17.9 2.9 1 23 1300 1322 1300 1322 0.99

23 25 4.4e-06 0.00031 21.2 2.3 1 23 1328 1350 1328 1350 0.97

24 25 3e-07 2.1e-05 24.8 2.6 1 23 1356 1378 1356 1378 0.99

25 25 0.00052 0.036 14.7 0.3 1 22 1384 1405 1384 1408 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00055	0.038	14.6	0.9	1	23	214	236	214	236	0.97
2	25	0.55	39	5.1	0.4	2	10	243	251	242	256	0.86
3	25	0.012	0.82	10.4	0.9	2	23	281	302	280	302	0.96
4	25	0.00064	0.045	14.4	0.7	1	23	377	400	377	400	0.94
5	25	2	1.4e+02	3.4	0.7	2	22	410	430	410	430	0.95
6	25	2.6	1.8e+02	3.0	0.8	1	22	439	460	439	463	0.88
7	25	0.0048	0.34	11.6	0.5	1	23	581	604	581	604	0.96
8	25	0.0093	0.65	10.7	0.1	1	22	613	634	613	634	0.95
9	25	0.0033	0.23	12.1	4.3	1	23	643	666	643	666	0.97
10	25	6.8e-05	0.0047	17.4	0.4	2	23	680	701	679	701	0.97
11	25	2.2e-05	0.0015	19.0	5.4	1	23	707	729	707	729	0.98
12	25	0.075	5.3	7.8	0.5	1	23	869	892	869	892	0.95
13	25	0.029	2.1	9.1	2.2	1	22	899	920	899	920	0.95
14	25	0.42	30	5.5	0.4	1	20	929	948	929	952	0.86
15	25	6.2e-05	0.0043	17.6	1.6	1	23	976	998	976	998	0.97
16	25	0.00047	0.033	14.8	0.7	1	23	1005	1027	1005	1027	0.98
17	25	0.13	8.9	7.1	0.0	2	21	1054	1073	1053	1074	0.94
18	25	0.041	2.9	8.7	4.0	1	23	1119	1142	1119	1142	0.96
19	25	0.007	0.49	11.1	1.5	1	23	1179	1202	1179	1202	0.96
20	25	0.015	1	10.1	3.1	1	23	1229	1252	1229	1252	0.97
21	25	1.4e-05	0.00099	19.6	0.1	2	23	1273	1294	1272	1294	0.95
22	25	4.8e-05	0.0034	17.9	2.9	1	23	1300	1322	1300	1322	0.99
23	25	4.4e-06	0.00031	21.2	2.3	1	23	1328	1350	1328	1350	0.97
24	25	3e-07	2.1e-05	24.8	2.6	1	23	1356	1378	1356	1378	0.99
25	25	0.00052	0.036	14.7	0.3	1	22	1384	1405	1384	1408	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATGTTTGTCGCACGTGTGCGCTGCAAGATGACAACTTGTTGGCGCTGGCAACACGTAGTGAGAAATACGCAAAGAAAAGTATCTGCGACATGCTGCACGAATTAACACAAAACGATCCACTACTGGAGCATACAGATGATAAGCTACCGCAGCATTTGTGCGGCCAATGCTTGAGCCAGCTGGAAGCAGCCTATGCATTTGTGCTGCAAGCCCGCGAGGCGCAggagcaactgttgctgcagctaCGCAAAGGATTGCAGACACAGTGCCTGGACGAAACACCTATCGATATAAGCATAGAACACATCAAAATCGAAACAGACATTGACCTAGATGCGGACACGGCTGATGCAGTTGATGCTGAGTttgaggaggagcaggagaagCATGTTGTCTTAAAATGTCAGCCGGAAACTGATAGCGATAGCAGTCAGGATAATGTGAAGGACCATGACGTTGAGGTCCAAACCCTGCAGCTGCGGCGCAGTGCTCGACGAGCCAAAATGAGCACAGACAGCGAAAATGAGTCAATCTCCGAGCAGGTGAAGCCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCCGACGTGTGGCCAAGAGGGAGACGACCACCAACGAGGATGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACCTTCTCCTGGTATCGCGACATGCAGCGCCATGCACGCATCCACTTCGAGCAGGCGGGCATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGATAAACATATACTGCCACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTATACAGTTCCGGCAGATTAATGCGTGTGGAGTGCAAACTGTGCGGATTGAGTTGCCAGCGCATTCGGGAGTTGCGCAACCACCTGGCGAGTCATGTTCACATTGAGACATTGTGGAATCTCAGTCTGGACAACGATGTCATCCGGGAGCAATTTGGCAGCCAATCGGATTTGGAGCAAATCAAGGAACAGGTCTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACGGCGCCGTGGTGAATGCCTACGGTTATGAGTTGTGCCTCAGCGACtcggatgaggaggaggatgaggagctgTCTGGCAAATATCAGTGTCTGCGCTGCAATGTCAACTTTGCACGCAAGTATCAACTCGTGCGTCACACGCTCGAGGAGCACACGGACAGAAGTGAAACTCCTTTGGAACGCTGCAATGTCTGTCAAATTGGCTTTGTTTGCGTCAAGCTGCTGGAGCAGCATCAGCGCACGCAGTGCCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAGCATGCATGCAGCAGGCTGCACCATGATCTTCAGCAGGAACTGCAGCATCGGcatcaggagcagcagcaggcacctCATCGTCAGATCCAGTGTTGCCTGTGCAATGACCGACCCAGCAGCATGGCTGCCCTACGCTCTCATTTACTCACTCATCGCGATGGACACACGGACATCGATCCGCATCAGCAGTCTGCCTTCTTTCGTACCTATTACCAGGATGACGGCGTCAGCAGCCTGCCGGAGATCAGGGTACGCATCGCTGTCGACTTTGAGGCTCAGCTTTATGGAAGATATTTCAATGCGTGTACGGACAGCGGACAGGAACTGGACTTCAACGACTCCGACAAGGAGTGGAGCGATGCGCCAGCTCTGCATAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATTGAGCTGGCGGGCGGACTGCCTCACGTCTGCTCAGATTGTGGATTGGGCTATGTGGCCGagtcgctgctgcagcagcatcgtcGTCGCATCTGCGCCAAGCTGCTTGCCAAGTACCAGTGTCCACATTGCAGTCAGCGGTTCTATTGGCACTCTAACTACGAGCGGCACATTCAGGTGCAACATCCTGCGGAGAGGCAGCAGGGGCAGGAGAAGAGCAAGCTTCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCTAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTCCAGTTCGAATGCGTCCACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCACATGCGGATGCACGGCGAGCAGCCGACGTCATCGTCTCTCGgtgagcagctgcagcgcatGCCGATGGTCTTGAGCCAGCTGTGTCGCGCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACAAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTTGAGGCTGTGTTTGGCCGAGGAGCGAGGCATCGCAAACATTTGTCGAGCTCTCTATCCAGAGCTGAACACGCCATTGAATCAGCAGGCTTTGATCAAGCGCATCCAGCGAGATCTGGGCAatgaactggagctggagagATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGACTCGGATTGTGCAGCAGAAACCGAACAGAGCTCCATGGAACGCGGTTATAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAATATCAGCTTTATGCCCACCAGCTGGAGAAGCACACGTGGCACCAGACAACGCACGTCTGCAGCCACTGCCAGGCGAGATTTGTAAATGAGCAGCTGCTGGACCATCACTATCGGACCCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCGTTGCGCTTTCGCTGGCGCGATAATCTCAAGCTGCACAATGGTGTAGCGCATCAGGAGCGAGGGAATGTAAAGCAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCTGTGGTTAGCTACGACTGCGTCGAGTGCAAGCGTAgcttcaaaatgcaaaaggaTCTCACACGGCACACACTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCTCGACGCTTCTATCGCGAGGCGAACCTGCTGCAGCACATCGAGCGCCATGGCATCAGCGCTGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGTCGTCATCCGCACGGCCCGAAGTGCATCAAGTGTCGCGTGTGTGAATTATCCTTTGGAAGCATTGCTGCACTGCGCTCGCATCTGCAATCGTCGGCAGTTGGCACTCATCATCCGATTGAGTCCATGGCCAACTATTCGATCACGAATCAGCTGGGTTACGAGCTGCACCTGGACGACTCCGAAACGGATGAGGAAGCCAAGCCGGCGGGCACCCCGGCGCATTACACGTGCGGCATGTGCCAGCTGCGTTGTGTGCGCAAGTTTGagctgcatcagcatcagcaggccATGCATCGTCTGGAGCGCATAGCCGACGGCTGCGATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTCAAGTGCTCTAAATGCAGCTACAAGTTTATGTGGCAATCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGTCGACAACGAAAACATCAATGCCCATGGCCGTGCCCGACATTGCCAACGCTGAGTGCCACATCTTCCAATGTGGTCAATGTCCCAGTAAATACAATCGGAAGGATCGCCTCACCGCCCATGTAAAAAAGTGTCACACAGCTGGCGCAACTGCGTCAACAAAATCGCCAGCGGTTGCCAAGCAGCAGAAAAGTTTCCTATGCGCCTTCTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCATACCGGCGAGAAGCCGTTTAAGTGTGATTACTGCGACATGGCATTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGTCTGCAAGAAGGGATTCGCTCGCTCCTacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATACGGCGCCACACGGGCGAGCGACCTTATCAGTGCAATACGTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGAATGCAGAATGGCCACTATGAGACGGAAGTGGGTCAATCGAAAGTTGACTAA
Protein Sequence: MLPTNVCRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQAREAQEQLLLQLRKGLQTQCLDETPIDISIEHIKIETDIDLDADTADAVDAEFEEEQEKHVVLKCQPETDSDSSQDNVKDHDVEVQTLQLRRSARRAKMSTDSENESISEQVKPLPVKRGRGRPRRVAKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKHILPRSSEWRYAERLYSSGRLMRVECKLCGLSCQRIRELRNHLASHVHIETLWNLSLDNDVIREQFGSQSDLEQIKEQVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDEELSGKYQCLRCNVNFARKYQLVRHTLEEHTDRSETPLERCNVCQIGFVCVKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACSRLHHDLQQELQHRHQEQQQAPHRQIQCCLCNDRPSSMAALRSHLLTHRDGHTDIDPHQQSAFFRTYYQDDGVSSLPEIRVRIAVDFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPALHSCAVCGESRIRLDQLLQHQQSQHIELAGGLPHVCSDCGLGYVAESLLQQHRRRICAKLLAKYQCPHCSQRFYWHSNYERHIQVQHPAERQQGQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECVHCDRKFHRKDGLKSHMRMHGEQPTSSSLGEQLQRMPMVLSQLCRANGCKQIKCMICLSQHTKISDLRTHLTSHQLRLCLAEERGIANICRALYPELNTPLNQQALIKRIQRDLGNELELERFVSITNEAGIELSLDSSETDTDSDCAAETEQSSMERGYSCELCQVQVMRKYQLYAHQLEKHTWHQTTHVCSHCQARFVNEQLLDHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQERGNVKQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIKCRVCELSFGSIAALRSHLQSSAVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEESTTKTSMPMAVPDIANAECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGATASTKSPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQNGHYETEVGQSKVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -