Basic Information

Insect: Drosophila tani
Gene Symbol: Mtf1
Assembly: GCA_008042535.1
Location: VNJO01002599.1:77350-86141[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00018 0.016 15.9 1.8 1 23 356 380 356 380 0.98

2 6 0.00011 0.01 16.6 0.2 1 23 386 410 386 410 0.98

3 6 7.3e-05 0.0064 17.2 1.0 1 23 416 440 416 440 0.97

4 6 2e-06 0.00018 22.1 5.3 1 23 445 467 445 467 0.98

5 6 1.2e-06 0.00011 22.8 3.2 1 23 473 497 473 497 0.99

6 6 0.00015 0.013 16.2 3.7 1 23 503 527 503 527 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00018	0.016	15.9	1.8	1	23	356	380	356	380	0.98
2	6	0.00011	0.01	16.6	0.2	1	23	386	410	386	410	0.98
3	6	7.3e-05	0.0064	17.2	1.0	1	23	416	440	416	440	0.97
4	6	2e-06	0.00018	22.1	5.3	1	23	445	467	445	467	0.98
5	6	1.2e-06	0.00011	22.8	3.2	1	23	473	497	473	497	0.99
6	6	0.00015	0.013	16.2	3.7	1	23	503	527	503	527	0.95

Sequence Information

Coding Sequence: ATGAacgatcagcagcagcaacactacTACCACCAGGGCAGCTGGAAGACGTCGGCGGCGACGGTCAACAGCCATGGAAATTCGTTATCAGACAGCCGGGATTACGATACGAACTCGTCGCGCACCTCGCTCTCCGGCTCCCCGCCCGCCGgtgccgcctcctcctcgtcgggcGCGTCATCCGTTTCTCTGGACTTTGAGGGCGGTTTCGGTGGCGGCCGGCCGCTGGCGCAGCTGCTCACACCCAAGCTGGAGGGGGACGGGAGCATCATCCATGGCGACAGCTACAGCTTGTACGGCAACTCCACCAGCGGGGCGGAGCAACAGGTGCTGAACCTAGAGCTGGCGACCACCTACAATGCCCTGTTCACGCAGGATGCAGGATCACCTGCAGCAGCTCACACACATCCACCATTAGTAACTGCGGTGCCGGCGGAGGCGCCAGACGAAATCTTCATCCTACCGCCTCCCAACCCGACGCCCCTGCCCATCACTGTCATACCCATCACATACCATCATCacaccgccagcagcagcagcagtgctgCCGAGTCCCTCATCAGCACCAGCATCGGCGAGGTGCCGCTGATAGCCACCTTGAGCGaggccagcggcggcggcggcggcttgggCGACGGCCAGGTGTACAATTTGGATGACATCTGCTTCACGCTGGAGTACCAGTTCGAGAACCAGAAGCTCGTCCAGGTGCAGCCCCCAACCGTGGTGTCCCTCAGCATGATGAGCACCACCTCAGCGGAGGGGGAAGCTCCTCCAGAGGCAGgtgcctcctcctctgcctccGCCAACTGTGATAATGGTCAGGCCACCTCGGTGGTCACTTCTCCGGCGTACTTCACTATCGAGACGAGCTATGTGGATGAGTACGATCCGAATGAGCTGGATGAGGACGAGCAGCTCTCCCACTGCATTCAACCAGGTGTTCTCCATAGAGATGttgacgaggacgaggaagatgaggatgaggaagcCGGCAGGCAGCAAGACGAGAACGATCAGCTAATGGCGATGGCCTACGAGAGTTCGGACGAGGCTCTTAGCCGCTATAGATGCAACTACGAGAACTGTTATCGGAGCTATAGCACCATCGGAAATCTGCGAACGCATTTAAAGACCCATACGGGCGACTACAGCTTCAAATGTCCGGAAGACGGCTGCAACAAGGCCTTCCTCACATCGTACAGCCTGAAGATCCACGTCCGCGTCCACACGAAGGTGAAGCCCTACGAATGCGAAGTGACCGGCTGTGATAAGGCCTTCAACACGCGCTACAGATTGCACGCCCACCTGCGCCTCCACAATGGCGAGACGTTCAACTGCGAGCTGTGCCAGAAGTGCTTCACCACGCTGAGCGACCTGAAGAAGCACACGCGCACCCACACCCAGGAGCGACCGTACAAGTGTCCGGAAGACGACTGTGGCAAGGCCTTTACTGCCTCGCATCATTTGAAGACCCACCGGCGAACGCACACCGGCGAGAAGCCGTATCCCTGCCAGGAGGACAGTTGCCAGAAGTCGTTCAGTACTTCGCACAGCCTCAAGTCGCACAAGAAGACGCACCAGCGGCAACTGCTCAACAAGGGGCGAAAGAAGCGGCCCCTCAAGTCGCAAACGAGCAAGCAGTTCAAGGATCAGGACCAGGAAAACCAGCCGGAGGAAAGGGAAGAGCAGTCAGAGATGTTGGTGCTAAATCCAGGCAGTCACAGCTCGGAGACGACGACGAGTACGGACAGCGGAGTGGTGCTGCATACGCTGCATACGCAGGATCCGCAGGATCATCAGTTGTCCAATGTGTTTATCCTGCAATCCGATGAGCCACTGATCCTGCCGGAGACCTCACAGGCCTACCAGCTCTCGTACGCCGCCGAGGAGGAGATACCCAGCCCCTGGATCGATGCTGGTGTCCTCGTCTCCAAGCCCATCATTCCCATGGCCCCCTTGACAGATGCATGCGTGGCCCTGCCCACCGAGATGCCAAGTTTTGTGGACTTGAAGCCCACCTACGGCAATGCGGTGAGCGGCAACATGGGGGGTGGTGATAACCAAGTGGAGACCATGGATGTGGACGCCACAGTACCGCCGCTGCCTTCGCTGCCTTCGCTGCCCACTCCCACGTTGGAGCTAAACCAGCAAAACATCGAGGAGCTGCTCAAGCAGGACAGCTTCGACAACGAGGAGGACATGGAGACGGAGTCGCTGCTGAACGACATCCTCATGACCATCGACAACAACAGCGCCCTGCTGCAGGCCACCCTCCAACAGGCCTCCCAGGTGCCCAGTGACGCCTCCGGACTGGTGGAGCTGGACATCAGGGACAACAAGCCGACGCTTAAGCAGATCACAGCGGATGCGGGCATCTGCAATTGCACCAACTGCAAGTGCGATCAGACCAAGAGCTGTCACGGCGGCGACTGtggtgcggcggcggcagcggcggcgggggctACTTCCCAGAAGGGAACCACCAAGGCAACTATTACCACGACAACCATCCAGAATTCCAGCGGTGGCAAACGTAtttgcggcggcggcaaaaaAGTGAGTAAACGCGAGGCCGAAATGAACCAGAACATCGAGGATGTTGCTTTGCTGCTGCAAAACCTGGCTTCCATGGGCACCGGCAGTTCCtccggcggtggcggcggttgctgcggcggcggcggtgcagCTGCCAAGCCAGCGCCAGCGTCAactggcggcggctgctgtgcGGAGACGAAGACTCCTCCTGAGCCCGTGAAGAGCGGTTGCGGCTGTGCCCAGACCGTAACTGCTCCCTCCGGCGGTGGTTGCTGCGGTGGTAGtgcgcctcctccgccgcctaCAGGAGGCTGCTGCAAGCCatcacctcctcctcctcctcctgtctcaggcggctgctgctctggACAGGCCAAAGCTCAGCCACCCGCAGCACCCGCTGCCGCCGTCAAGGGCAACTCCTGTACCTGCAAGAGTCCAGCCGAGGGCGTGGCCAATGGCTGCTGCGTGGTGATCTGTATTAAAACGCTGCAAGCGCTCCGCAAAGTTCTGACGCGCCGGAATCTGAACCTAATGCTTTGTCCACAGCAGAACTAA
Protein Sequence: MNDQQQQHYYHQGSWKTSAATVNSHGNSLSDSRDYDTNSSRTSLSGSPPAGAASSSSGASSVSLDFEGGFGGGRPLAQLLTPKLEGDGSIIHGDSYSLYGNSTSGAEQQVLNLELATTYNALFTQDAGSPAAAHTHPPLVTAVPAEAPDEIFILPPPNPTPLPITVIPITYHHHTASSSSSAAESLISTSIGEVPLIATLSEASGGGGGLGDGQVYNLDDICFTLEYQFENQKLVQVQPPTVVSLSMMSTTSAEGEAPPEAGASSSASANCDNGQATSVVTSPAYFTIETSYVDEYDPNELDEDEQLSHCIQPGVLHRDVDEDEEDEDEEAGRQQDENDQLMAMAYESSDEALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCNKAFLTSYSLKIHVRVHTKVKPYECEVTGCDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHTRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLLNKGRKKRPLKSQTSKQFKDQDQENQPEEREEQSEMLVLNPGSHSSETTTSTDSGVVLHTLHTQDPQDHQLSNVFILQSDEPLILPETSQAYQLSYAAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALPTEMPSFVDLKPTYGNAVSGNMGGGDNQVETMDVDATVPPLPSLPSLPTPTLELNQQNIEELLKQDSFDNEEDMETESLLNDILMTIDNNSALLQATLQQASQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGAAAAAAAGATSQKGTTKATITTTTIQNSSGGKRICGGGKKVSKREAEMNQNIEDVALLLQNLASMGTGSSSGGGGGCCGGGGAAAKPAPASTGGGCCAETKTPPEPVKSGCGCAQTVTAPSGGGCCGGSAPPPPPTGGCCKPSPPPPPPVSGGCCSGQAKAQPPAAPAAAVKGNSCTCKSPAEGVANGCCVVICIKTLQALRKVLTRRNLNLMLCPQQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00485394;
90% Identity: iTF_00483195;
80% Identity: -