Basic Information

Insect: Drosophila tani
Gene Symbol: esg
Assembly: GCA_008042535.1
Location: VNJO01000992.1:30274-32394[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 7.2e-06 0.00063 20.3 3.7 1 23 275 297 275 297 0.99

2 6 7.3e-06 0.00064 20.3 3.7 1 23 352 374 352 374 0.97

3 6 1e-06 9e-05 23.0 0.6 1 23 387 409 387 409 0.98

4 6 3.2e-08 2.8e-06 27.7 0.4 1 23 413 435 413 435 0.97

5 6 3.6e-08 3.2e-06 27.6 2.1 1 23 441 463 441 463 0.98

6 6 4.8e-06 0.00042 20.9 0.4 1 21 469 489 469 490 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	7.2e-06	0.00063	20.3	3.7	1	23	275	297	275	297	0.99
2	6	7.3e-06	0.00064	20.3	3.7	1	23	352	374	352	374	0.97
3	6	1e-06	9e-05	23.0	0.6	1	23	387	409	387	409	0.98
4	6	3.2e-08	2.8e-06	27.7	0.4	1	23	413	435	413	435	0.97
5	6	3.6e-08	3.2e-06	27.6	2.1	1	23	441	463	441	463	0.98
6	6	4.8e-06	0.00042	20.9	0.4	1	21	469	489	469	490	0.95

Sequence Information

Coding Sequence: ATGGATAAACTTAAGTACAGCCGCTGTCCGCTCAAGAAGCGTCCGATAATGGTGGAGGAGTCCTGTCAGGAGGATCACTTAAGTCACGACGAAGGACCCGTGGACTTGAGTGTAGCCTCGGCAGCTGTTCCCCTGGAACCGCATTGGTCGGCGAAAGCGGAACCGGAACCGCAGGCCGTGCCCACGGAGCTGAGGCGTCGCTTCGACGCGGCCATGAATCAGACCAAAGAGCAGCTGGCCCGCCGCATTTGGGAGGAGACCCGGGAGATAGCGCGTGCCTTTCCCGACGTCTTTACCCGCGAAGAGATCGCCAAGAGCCTGGCCCGCCTGGGTTACGGCGAGTTCGAGCTGCCCCCCGAGGAGGAGGTAATggaacccgaacccgagccAGAACCTcaaccagagccagagcagcaAATTCCGCTGAGCTATGCCAGAGAGCCTGGCCAGACCATCATCAAGGTAGAGCCCACGGAGCAGGACTTTCCCCTGCGGAACTACAACAATAATCTGCTCAAGAGCATAGCCGAGTACGAGGACTGCATGAAGATGCAGCCCAtcaaggaggagctggtgcCTGTGCCCCAGCCGCCGATGTACTATCCGCCGCCCACGCCGCTGGCCGAGCCCGAGGATCTCTCGGTGACCCAGAGGCGGGTGCTCAACGAGAACATGAATCTGCAGAACGTGGCCAGGGCTCTGCTCAGCATGCAGCACATGgccccgcagcagcagcacccggTGCCCCCGCAGGACATGGAGGAGGACCAGGAGAACCAGGACCTCAATCCGCTGAAGATCAAGAGCAGCAACGACCTGTACTACCAGTGCCAGCAGTGCAACAAGTGCTACTCCACCTACGCCGGCCTGGTGAAGCACCAGCAGACCCACGCTTACGAGAGCACCGAGTACAAGATCATCCGGAGTCAGCCGGGCGGATCGGGTCCCATCGTGGACCAGACGGAGTTCTGCACGGACCAGGCATCGGCCCTGATCCAGGCGGCCAACGCCGCCTCGGCCCAGAGCATGCAGAAGCCGGTGGGAGTGCCGAGGTACCACTGCCAGGACTGCGGCAAGAGCTACTCCACCTACTCCGGCCTGTCCAAGCACCAGCAGTTCCACTGCCCCTCGGCGGAGGGCAACCAGGTGAAGAAGGTGTTCAGCTGCAAGAACTGCGACAAGACCTACGTCTCGCTCGGGGCCCTCAAGATGCACATCCGCACCCACACGCTGCCCTGCAAGTGCCCCATCTGCGGCAAGGCCTTCTCGCGGCCCTGGCTCCTTCAGGGACACATCCGCACCCACACGGGCGAGAAGCCCTTCAGCTGCCAGCACTGCAACCGAGCTTTTGCGGATCGCTCCAACCTCCGGGCTCACATGCAGACCCACTCGGACGTGAAGAAGTACTCCTGCCCCACCTGCACCAAGTCCTTCTCCCGGATGTCCCTGCTGGCCAAGCACCTGCAGAGCGGCTGCCAGAGCGAGCAGATCGGAGGTCCCGGTGGCTCATCTGGCGGTGGCttcgaccagcagcagctgcagcagcacctccAAGGATACGAGGAGGGCCACAGCCCCCACCAGGTCTACTATGCCGGCAGCGtgggcagcagcaacggcgacgaggaggaggccggAGACTTCCACATGCCGCCACCAACCACCTTATATTAA
Protein Sequence: MDKLKYSRCPLKKRPIMVEESCQEDHLSHDEGPVDLSVASAAVPLEPHWSAKAEPEPQAVPTELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEPEPEPQPEPEQQIPLSYAREPGQTIIKVEPTEQDFPLRNYNNNLLKSIAEYEDCMKMQPIKEELVPVPQPPMYYPPPTPLAEPEDLSVTQRRVLNENMNLQNVARALLSMQHMAPQQQHPVPPQDMEEDQENQDLNPLKIKSSNDLYYQCQQCNKCYSTYAGLVKHQQTHAYESTEYKIIRSQPGGSGPIVDQTEFCTDQASALIQAANAASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQSEQIGGPGGSSGGGFDQQQLQQHLQGYEEGHSPHQVYYAGSVGSSNGDEEEAGDFHMPPPTTLY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486734;
90% Identity: iTF_00602776;
80% Identity: -