Basic Information

Insect: Drosophila takahashii
Gene Symbol: -
Assembly: GCA_018152695.1
Location: JAECXN010000118.1:9414379-9416261[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00022 0.013 15.7 0.1 3 23 229 249 228 249 0.98

2 12 1.4e-05 0.00088 19.4 3.2 3 23 261 281 259 281 0.96

3 12 7.6e-06 0.00047 20.3 0.6 1 23 287 309 287 309 0.99

4 12 2.6e-08 1.6e-06 28.0 2.3 1 23 315 337 315 337 0.98

5 12 3.2e-06 0.0002 21.4 1.3 1 23 343 365 343 365 0.98

6 12 3e-07 1.8e-05 24.7 1.1 1 23 371 393 371 393 0.99

7 12 1.3e-07 7.8e-06 25.8 2.9 1 23 399 421 399 421 0.99

8 12 1.9e-06 0.00012 22.1 5.5 1 23 427 449 427 449 0.99

9 12 1.4e-05 0.00087 19.4 0.8 1 23 455 477 455 477 0.98

10 12 0.00041 0.026 14.8 0.9 1 19 485 503 485 507 0.93

11 12 0.00017 0.01 16.0 2.3 1 23 517 539 517 539 0.98

12 12 0.00034 0.021 15.1 3.0 1 23 544 566 544 566 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00022	0.013	15.7	0.1	3	23	229	249	228	249	0.98
2	12	1.4e-05	0.00088	19.4	3.2	3	23	261	281	259	281	0.96
3	12	7.6e-06	0.00047	20.3	0.6	1	23	287	309	287	309	0.99
4	12	2.6e-08	1.6e-06	28.0	2.3	1	23	315	337	315	337	0.98
5	12	3.2e-06	0.0002	21.4	1.3	1	23	343	365	343	365	0.98
6	12	3e-07	1.8e-05	24.7	1.1	1	23	371	393	371	393	0.99
7	12	1.3e-07	7.8e-06	25.8	2.9	1	23	399	421	399	421	0.99
8	12	1.9e-06	0.00012	22.1	5.5	1	23	427	449	427	449	0.99
9	12	1.4e-05	0.00087	19.4	0.8	1	23	455	477	455	477	0.98
10	12	0.00041	0.026	14.8	0.9	1	19	485	503	485	507	0.93
11	12	0.00017	0.01	16.0	2.3	1	23	517	539	517	539	0.98
12	12	0.00034	0.021	15.1	3.0	1	23	544	566	544	566	0.97

Sequence Information

Coding Sequence: ATGGAAAAATCGTCGGACGCCATCGCGGGAAAGAACTGCCGAGCGTGCGCCGAACACTCGGCAATTCTGGTGGACCTCTTCTCAACGGACATTTCCGATCCGCCTATTTGGGAAATGCTGAACTCCTTTCTCCCCGAGAACTGCCGCGTCAACCGGGATGCAATGCCGCAGAAGATCTGTCCAACCTGCCTGGTGGCCGCCCAAAATGCCTTTTACTTCAAGAACAAGTGCGAGCAGAGTTTCCAGTACTTTACGCACCTCCTCTCGCTGGACAAATCCGCCACAAATCATGGTAAAACTCGGGGCAGAAGAGGTGACAAGAATCCACTGAAAACTTTCGAAATGGTCGGCTGCGAGGATCCGCTGGACACTAATGTTTCTGGAAAGGAGGTGGATCGGCTTGATCTGAAAACGGGTAATGATTCCGAGCTGGCAGATGGATTGCTAACTACAGAACAGGAAACCCAACCGTTGCATGAAGTATTTGAAATAACTTTGGGAGATATAAAAACAGAAGAAGAAATTTCCAACGATGAGACATTCGAAGATGCTTTCGCAGAGGACTATAATAATGATGATGAATCTGAGAGTGAGTCTGATGAATGGTCAGAGGACGAAGACGAGCCCTGGATGACAGGCAAAGGAGAGCCAAAAACGGATGGCGACGAGAATCAATCGCTGCTGTGCACCGAGTGTGGGGTGACCTATCCGACAGAGAAGTCGTTGGCGAAGCACATTGCCAGGCACCGGGCGCAGGATGATCCACAAAAGCCGCACCTGTGCGACTTCTGTGGCAGAGGATTCCGGACGAACGCCCAGCTGACAACCCACAGGCGCAAGCACACCGGAGAGCGTCCATTTCAATGCCCCCTCTGCCCGAAAGCGTATACGCACGGTCCAACTCTCAAGTCGCACATGCTCACCCACGACGAGCAGAAGGCCCATAAGTGTCCGGAATGCGACAAAACCTTTTACACTAGGGGCAACCTGAGGGCCCACATAAAGCGGCACTCAGGCGAAAGACCATATAAGTGTCCTGATTGTTCACAGACCTTCACGAAGAACTCGGGCCTTAAACTGCACAGTCGGCTGCATAAGGAGGAGCGTCCCTTTAAGTGCGACCTGTGCGGCAAGGGATTTGTCCAGAACCAGCATTTAATCACGCACTTGCGGGTCCACAACGGGGACCGCCAGTTCAAGTGCCCCGACTGCGACAAGCGCTTCTTCGAGAAATCCAACATGATGAAGCATCAGCGCACGCACTCGGGCATAAAGCCATTTAAATGCGCCGAGTGCGGCCAAGCATTCTCGCACAACCATCATCTGAAGAGTCACCTGCGCATCCACACCGGAGAAAAGCCCTACAAATGCGACCAGTGCGGCAAGGGTTTCTGCGCGAATCAGTCTCTTGCCAAACATATCCTCTGGCATGTGGAGAACAACGATCGGCCCTTCAAATGCACCAAATGCCCCAAAGCCTTTGACTCACAGCAGAGTTTACGGGGCCACGACAAGGCGCACAGAAAGCCAGAAGGACCGAAAACACTGCACCAATGCCCACACTGCGACGTCAGCTTTGCCATAAAGAAAACATTGGACAAGCATATTAGTAGTCATAAGATTCGGCCCCACCCTTGCCCGCATTGTAGCGAAGGATTTTTCTCCCTGAAGAGCTTAGACAGACACCTTAAAACGCACAAAACGAAGGAATAA
Protein Sequence: MEKSSDAIAGKNCRACAEHSAILVDLFSTDISDPPIWEMLNSFLPENCRVNRDAMPQKICPTCLVAAQNAFYFKNKCEQSFQYFTHLLSLDKSATNHGKTRGRRGDKNPLKTFEMVGCEDPLDTNVSGKEVDRLDLKTGNDSELADGLLTTEQETQPLHEVFEITLGDIKTEEEISNDETFEDAFAEDYNNDDESESESDEWSEDEDEPWMTGKGEPKTDGDENQSLLCTECGVTYPTEKSLAKHIARHRAQDDPQKPHLCDFCGRGFRTNAQLTTHRRKHTGERPFQCPLCPKAYTHGPTLKSHMLTHDEQKAHKCPECDKTFYTRGNLRAHIKRHSGERPYKCPDCSQTFTKNSGLKLHSRLHKEERPFKCDLCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKRFFEKSNMMKHQRTHSGIKPFKCAECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFCANQSLAKHILWHVENNDRPFKCTKCPKAFDSQQSLRGHDKAHRKPEGPKTLHQCPHCDVSFAIKKTLDKHISSHKIRPHPCPHCSEGFFSLKSLDRHLKTHKTKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536909;
90% Identity: iTF_00536909;
80% Identity: -